National Scientific Center "M.D. Strazhesko Institute of Cardiology"
Question
Asked 4 August 2017
Does increased magnesium intake decrease plasma cholesterol and triglyceride?
Several studies have demonstrated supplementing "at risk" high cholesterol groups with magnesium reduces bad cholesterol levels. In some studies the reduction of cholesterol is quite significant even with modest amounts of magnesium (400-800 mg per day) usually as a supplement.
Unfortunately, there have not been any long-term studies to see if supplementation with magnesium does reduce the risk of heart disease or stroke.
In this study magnesium use as the nutrient.
What about use magnesium for decrease Cholesterol in clinical practice?
Most recent answer
Additional information. I ask this question because:
cardiomagnyl included two active material: acetylsalicylic acid 75 mg and magnesium hydroxide 15.2 mg. Part of the cardiomagnyl - magnesium hydroxide protect the gastrointestinal mucosa against acetylsalicylic acid.
It is small dose of magnesium hydroxide, but if we have any relations between magnesium intake and level of colesterol (with or without statins).
All Answers (7)
Mexican Institute of Social Security
According to the present study only in nephropathies a beneficial effect was seen
We conclude that patients with chronic kidney disease undergoing MHD show positive correlation between serum Mg and serum HDL, LP-a and TG. The abnormalities of lipid metabolism, such as hyper-triglyceridemia, elevated LP-a and low HDL-c, could contribute to atherosclerosis and cardiovascular disease in these patients.
National Scientific Center "M.D. Strazhesko Institute of Cardiology"
Thanks a lot Luis for your answer!
Good work and interesting results.
Are you treatment those patients with statins?
Often patients with end stage renal dysfunction has high level of TCh and TG.
National Scientific Center "M.D. Strazhesko Institute of Cardiology"
Thanks a lot for your comment.
This data show no benefit magnesium intake in AMI patients. But my question not addressed to those patients.
If we talk about patients with AMI little data available about using magnesium additional to GIK. Unfortunately all those study no show limitations of infarct size and not improve clinical endpoint. In our country 15 years ago we use GIK+Mg, but after publications results CREATE-ECLA and DIGAMI 2 we stop to treatment (corrected by SK).
But I have no data to study cholesterol in RCT with medications like magnesium.
GUPTA MEDICAL CENTRE Migraine-Headache Institute
There are no such data. I have been at the forefront of magnesium-related research and therapy for over two decades.
Magnesium is not used as part of GIK infusion. Try to think hard and long before responding.
All I can say is, keep trying if you must????!!!!
National Scientific Center "M.D. Strazhesko Institute of Cardiology"
Thanks a lot Vinod for your comment. I agree that Mg not used in CREATE-ECLA and DIGAMI 2 study. But as I write in previous answer we have little experience to use Mg additional to GIK in AMI patients. Yes, we do not have benefit to infarct size benefit end clinical outcome.
But first of all my question was not about patients with AMI, please be careful to answer on main question. I do not planing any study with MG in AMI patients. As for me it is enough data according evidence based medicine no benefit Mg in AMI patients.
National Scientific Center "M.D. Strazhesko Institute of Cardiology"
Additional information. I ask this question because:
cardiomagnyl included two active material: acetylsalicylic acid 75 mg and magnesium hydroxide 15.2 mg. Part of the cardiomagnyl - magnesium hydroxide protect the gastrointestinal mucosa against acetylsalicylic acid.
It is small dose of magnesium hydroxide, but if we have any relations between magnesium intake and level of colesterol (with or without statins).
Similar questions and discussions
What is the effect of magnesium on health?
Tareq Abdhilkadhim Naser Alasadi
Magnesium is very important, st facts on magnesium
Here are some key points about magnesium. More detail and supporting information is in the main article.
- Magnesium is vital for the proper functioning of hundreds of enzymes.
- Consuming adequate magnesium might help reduce premenstrual symptoms.
- Sunflower seeds, almonds, and shrimp are some of the foods high in magnesium.
- Magnesium supplements can interact with different drugs, so it is best to check with a doctor before taking them.so why magnesium is still necessary?
Related Publications
Zinc, magnesium, and vitamin K are important nutrients for humans. There are various factors that contribute to the development of their deficiency, which might result in or exacerbate various diseases. These nutrients can also interact with vitamin D metabolism and activity. This review discusses the main aspects of zinc, magnesium and vitamin K m...