Cross-lagged design - adjusted for the presence of outcome at T1?

Efforts to develop integrated care should focus more on the integration of physical and mental health.

There is much that can be achieved within existing structures to bring together mental and physical care at the clinical level. But this needs to be supported by wider changes such as development and evaluation of new service models, changes to professional education and increased use of new payment systems and contracting models.

Treatment of Bipolar Depression

I have to run a pearson correlation analysis between HPA axis markers- cortisol , ACTH and inflammatory marker IL-6(analysed through ELISA) and Depression anxiety questionnaires which were recorded at baseline and post interventions. I also need check the data for normality before running the analysis. If someone can provide an appropriate suggestion.

The bio-markers could also be influenced by other disease patterns

I am especially interested in clarifying whether variables such as duration of illness, duration of medication, age at onset, hospitalization, number of depressive episodes etc. can be suggested as possible moderators for the relationship between depressiveness (BDI score) and different declarative memory functions in clinically depressed patients. Additionally, I am not quite sure whether to perform a moderation analysis instead of a mediation analysis and if it is a commonly accepted method of choise for this issue.

See above

Hello

I am trying to assess effectiveness of cognitive remediation therapy on schizophrenia and depression patients.

I divided both the groups (schizophrenia and depression) into 2 groups (experimental and control group) and took data from my patient three times (Pre intervention, post intervention and after follow up of 6 months). I have pre, post and follow up data of schizophrenic patients (Experimental group and control group) and depression patients (experimental group and control group).

Now I want to asses that this therapy was more effective for schizophrenia or for depression.

can you please suggest me which statistic should I use to evaluate its efficacy.

Is that ok with using high-risk suicide in MINI (mini international neuropsychiatric interview) as outcome in major depressive disorder ?

If no, is there any  clear or general definition for the outcome of high-risk suicide in major depressive disorder ? Such as suicide attempt ?

This is a very unfortunate argument that to this day may still come up when you talk to lay people and professionals as well. Do you think this is simply a defence mechanism put up in order as not too have to deal with one's own difficulties addressing the issue? Is there any other reason that this  is so deep routed that the statement for some has nearly proverbial character?