Lab

Ravi Kumar Reddy Juturi's Lab

Featured research (21)

Expedited approval processes push new drugs to the market faster than ever. Regulatory Authorities of the United States (US) and European Union (EU) are using different approval pathways to cut down the time it takes to conduct a clinical review. Conventional drug discovery is a costly and time-consuming process. A study found that pharmaceutical industries spend an average of $3 billion in R&D activities, and more than 10 years are required to develop and market one new drug. Patients can hardly wait 10 years for a lifesaving drug. For this reason, in the field of new drug discovery, Regulatory authorities and pharmaceutical companies are pursuing a strategy that expedites the approval of certain drugs that treat severe conditions and address unmet medical needs. Expedited approval processes could attract attention as a solution to dramatically reduce the time and cost required for the new drug discovery. In this article, it is pre-sented with different expedited approval processes in the US and EU with an illustration of these speedy approval processes by taking Crizotinib drug for a better understanding.
In Europe there are very high expectations regarding the quality, safety, and efficacy of medical devices. But in reality, it fails, due to many scandals that threatened the lives of thousands of people. So, the EU has introduced the new regulations in medical devices to meet the expectations. The old directives such as medical device directive (MDD) and active implantable medical device directive (AIMDD) are now replaced with medical device regulation (MDR), and in vitro diagnostic medical device directive (IVDD) is replaced with in vitro diagnostic regulation (IVDR). When compared to MDR there are more significant changes introduced in the IVDR. The New Regulations has a hard deadline for certifications and manufacturers cannot launch their product without certification, hence manufacturers have to meet the new regulations within the given time frame. The change in regulation brings a disturbance for the medical device industry. The manufacturers have to make strategic decisions to streamline their innovation pipeline and R&D processes in response to the increased cost of compliance and longer product certification time, so it is essential to conduct the SWOT analysis to evaluate the effect of new regulations. To bridge the gap between the new and old regulations, Gap analysis should be done. Gap analysis is used as a tool that helps to monitor the quality management system and is mainly useful where Standards and regulations are updated. This analysis may add value to reforming the portfolio. The regulatory authorities have to focus on the problems faced by manufacturers and try to resolve the issues as soon as possible.
In the most ancient Indian texts, in the Rigveda, one of the hymns famously known as ‘nasadiyasuktham’ says when there was neither existence nor nonexistence what existed? In profound depths what existed at the beginning from which everything else has emerged. Answers to these questions were found, in the most ancient times. In the Vedas and Upanishads, these answers are found. But the questions are asked again and again and answers are restated. It is the wisdom of the ancient philosophers but now stated in the language of modern scientists. As far as the macrocosm (the universe) concerns the ancients are contributed a lot, now our understanding is much deeper with modern physics and cosmology. As far as the microcosm (mind & consciousness) concerns Vedanta and other Indian systems of Philosophy have very valid and deep insights. This is much more than modern understanding given by consciousness studies. Modern science has an edge over ancient wisdom in describing the universe with the help of physics, chemistry and describes the body with the help of biology and physiology. But closer and closer it comes to ourselves; the ancient wisdom is better than modern science. A grand synthesis and profound understanding of Indian Ancient philosophy on macrocosm & microcosm, root cause of human suffering, ancient wisdom to remove suffering, “Law of Karma” and its implications are presented in detail in this article.
For thousands of years, human beings have been exploring the fundamental nature of the world and the self. In this process, modern science and Vedanta philosophy do not differ in conceiving the physical body as a material and mind also as a material. But now and then, the question is asked that so-called matter is not sentient, it cannot be aware or conscious, and how does matter suddenly become conscious/aware/sentient being? For this reason, consciousness studies have become very important in the last two to three decades and it has opened up. These studies are now turn out to be multidisciplinary by the interest of brain scientists, neuroscientists, psychologists, philosophers of mind, language, physicists, computer scientists, Artificial Intelligence. A lot of work has been done in this field of science to address what is this subjective conscious experience which a human being has internally. Consciousness studies are not new in the east, about two to three thousand years ago texts called Upanishads which are originated from Vedas are clearly stated about consciousness and its nature. In this article, the nature of consciousness is discussed and demonstrated according to Advaita Vedanta Philosophy. The article also encompasses the standpoint of modern science on consciousness. Finally, an attempt is made to answer the so-called hard problem of consciousness from the Advaita Vedanta perspective.
This article comprehends the actual goal, philosophy and practice of meditation prescribed in the ancient Yoga system of Patanjali and Vedanta. Meditation is very popular in present days, especially in the west becoming increasingly popular and rightly so as it offers lots of benefits, which is already researched and published. Many schools of Meditation have come to west from east, for instance Yogic Meditation (Hatha Yoga) at the beginning followed by Zen Meditation and transcendental meditation and many other forms of meditation. Presently Mindfulness is well acknowledged meditation in the west, which helps in controlling the wondering mind to calm down by anchoring the attention to the breath means paying attention to the rhythm of breathing cycles. Therefore, the focus of the mind can be attained by effort of meditation, it means the distracted mind can be transformed into concentrated mind by a process of meditation. According to Yoga and Vedanta objective of the meditation is 'self-realization', which means true recognition of the self as the 'witness consciousness' which is beyond the mind, it is not to be manufactured and it is not to be attained, it is always there and natural, which is the true nature of individual being, but it cannot be objectified, it is has to be recognised subjectively as the true self by which every objective experience is possible and to get this realization is the actual goal of meditation.

Lab head

Ravi Kumar Reddy Juturi
Department
  • Pharmaceutical Regulatory Affairs
About Ravi Kumar Reddy Juturi
  • Current Interests are: 1. Pharmaceutical Regulatory Affairs 2. Value Based Education and its implementation in higher studies 3. Universal Human Values 4. Ancient Indian Philosophy especially Sankara Vedanta Philosophy and understanding the greatness of Indian Rishis and Scriptures and its immense applications for the modern science, Ontological Ethics, Humanities and restoring the Values, happiness, prosperity and Peace in the Society.

Members (4)

Sita Priya Darsini Yallabandi
  • Shri Vishnu College of Pharmacy
Sujatha Katru
  • Shri Vishnu College of Pharmacy
Ruchitha Bandla
  • Master's Student
Naga Lakshmi Nandini
  • Shri Vishnu College of Pharmacy
Deepika Majety
Deepika Majety
  • Not confirmed yet
Lakshmi Sravanti
Lakshmi Sravanti
  • Not confirmed yet
Arathi Metta
Arathi Metta
  • Not confirmed yet