Thérapie

Published by EDP Sciences
Online ISSN: 1958-5578
Publications
Article
This paper considers the prerequisites for gene therapy. This new field of therapeutics has not yet proved its efficacity nor its safety. Use, as a drug of DNA molecules which can modify host genome and environment as well requires specific prerequisites; among them, animal experimental models are essential despite their limitations. The different preclinical and clinical steps in the design of gene therapy studies are also discussed.
 
Top-cited authors
Bernard Begaud
  • University of Bordeaux
Ghada Miremont
  • University of Bordeaux
Hélène Théophile
  • Université Victor Segalen Bordeaux 2
Jean-Louis Montastruc
  • Faculte de médecine université de Toulouse France
Cécile Droz
  • Université Victor Segalen Bordeaux 2