Pediatric Neurology Briefs

Published by Pediatric Neurology Briefs Publishers

Online ISSN: 2166-6482

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Print ISSN: 1043-3155

Neurologic Sequelae of Enterovirus 17 Infection

April 2007

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21 Reads

J. Gordon Millichap

The long-term neurologic sequelae, neurodevelopment, and cognitive function of 142 children with a history of enterovirus (EV) 17 infection with CNS involvement were determined in a study at the National Taiwan University Hospital, Taipei; and Chang Gung Children's Hospital, Taoyuan, Taiwan.

Methylphenidate Usage for ADHD in the 1990s

January 1997

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12 Reads

J. Gordon Millichap

The usage and usage trends for methylphenidate (MPH) treatment of ADHD from 1990 through 1995 were estimated by the Departments of Psychiatry and Pediatrics, Johs Hopkins University School of Medicine, Baltimore County Health Department, and the Schools of Pharmacy and Medicine, University of Maryland, Baltimore, MD.

Hand Involvement in Charcot-Marie-Tooth Disease 1A

December 2008

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15 Reads

J. Gordon Millichap

Hand strength, function and disease-related symptoms were determined in 84 children, aged 2-16 years, with Charcot-Marie-Tooth disease type 1A (CMT1A) at University of Sydney, Children’s Hospital at Westmead, and Royal Children’s Hospital, Parkville, Australia.

Charcot-Marie-Tooth Disease Type 1A: Axonal Lesions

August 2000

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69 Reads

J. Gordon Millichap

The clinical and electrophysiological phenotype in 42 patients with Charcot-Marie-Tooth disease type 1A (CMT1A) were analysed at Wayne State University, Detroit, MI.

Ilae Revised Classification and Terminology of Seizures and Epilepsies, 2005-2009

May 2010

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51 Reads

J. Gordon Millichap

The International League Against Epilepsy (ILAE) Commission on Classification and Terminology has revised concepts, terminology, and approaches for classifying seizures and forms of epilepsy, last updated in 1981 for seizures and in 1989 for epilepsies.

Narcolepsy and 2009 H1N1 Pandemic in China

October 2011

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154 Reads

J. Gordon Millichap

Onset of narcolepsy in China (1998–2010) is seasonal, with a 6.7-fold increase from November (least frequent) to April (peak frequency).

Third Ventricle Enlargement in Neonates with Trisomy 21

May 2006

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4 Reads

J. Gordon Millichap

Measurements of routine head sonographic scans of 57 term infants with trisomy 21 born between 2000 and 2005 were performed within 7 days after birth and were compared with scans of 21 randomly selected, healthy, term infants without trisomy 21 at Shaare Zedek Medical Center, Jerusalem; Ben Gurion University of the Negev, Beer Sheva; and Hadassah University Hospital, Jerusalem, Israel.

Hypothyroidism and Chromosome 21 Deletion

September 1996

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11 Reads

J. Gordon Millichap

A 12-year-old mentally retarded girl with a large deletion of the long arm of chromosome 21 and congenital hypothyroidism is reported from the Department of Clinical Genetics and Pediatrics, University Hospital, Uppsala, Sweden.

Spinocerebellar Ataxia 21 with Retardation

November 2014

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22 Reads

J. Gordon Millichap

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John J Millichap

Investigators at Universite de Lille Nord de France, and other centers in France, report the identification of a novel causative gene for spinocerebellar ataxia 21, an autosomal dominant disorder, initially mapped to chromosome 7 and designated as SCA21.

Ring 22 Syndrome and Polyembolokoilomania

Article

February 1994

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6 Reads

J. Gordon Millichap

A 24 year-old severely retarded, hyperactive woman with a long history of foul smelling discharge from the nasal fossae, requiring removal under general anesthesia of foreign material (rocks, crayon, cotton, paper) on 9 separate occasions by an ENT surgeon, is reported from my own practice records in Chicago.

Neuropsychological and Language Deficits in 22q11.2 Deletion Syndrome

July 2014

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22 Reads

J. Gordon Millichap

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John J Millichap

Investigators at Bambino Genu Children's Hospital, Rome, and multiple additional centers in Italy conducted a retrospective and prospective study of clinical manifestations at diagnosis and during follow-up of 228 patients with 22q11.2 deletion syndrome.

Neurobehavior and MRI in 22ql3.3 Deletion Syndrome

September 2008

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6 Reads

J. Gordon Millichap

Neuromotor, sensory, language, communication and social development, and cerebral MRI and PET studies were performed in 8 children with 22ql3.3 deletion syndrome, at the National Institutes of Health, Necker-Enfants Malades Hospital, and other centers in Paris, France.

Brain MRI Anatomical and Attention and Behavior Disorders With 22qll.2 Deletion Syndrome

May 2006

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5 Reads

J. Gordon Millichap

The brain anatomy of 39 children and adolescents with 22qDS (mean age 11 years; IQ 67) and 26 sibling controls (mean age 11 years; IQ 102) was compared using MRI and automated voxel-based morphometry, and behavioral differences were correlated with affected brain regions in a study at King’s College, Institute of Psychiatry, London, UK; Royal College of Surgeons, Dublin, Ireland; and Academic Medical Center, Amsterdam, Holland.

Recurrence Within 24 Hours of Unprovoked Seizures

September 2006

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14 Reads

J. Gordon Millichap

The incidence and risk factors of acute recurrence of unprovoked seizures within 24 hours of admission to an Emergency Department (ED) were analyzed by a retrospective chart review at Schneider Children’s Hospital, New York.

Genetics of Motor and Sensory Neuropathy Type 2C

May 2000

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14 Reads

J. Gordon Millichap

Thirty-three subjects in a large family with hereditary motor and sensory neuropathy (HMSN) type 2C were examined by linkage analysis at the Mayo Clinic, Rochester, MN.

Coenzyme Q10 Deficiency and Type 2C Muscle Fibers

December 2013

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23 Reads

J. Gordon Millichap

Investigators at Washington University School of Medicine, St Louis, MO, evaluated retrospectively clinical, laboratory, and muscle histochemistry and oxidative enzyme characteristics in 49 children with suspected mitochondrial disorders.

CytochromeP450 2D6 and Atomoxetine Metabolism

October 2010

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15 Reads

J. Gordon Millichap

The relation of cytochrome P450 2D6 (CYP2D6) activity to metabolism, response and adverse effects of atomoxetine was determined by CYP2D6 genotyping in 10 out of 100 children treated for attention deficit hyperactivity disorder at Amphia Hospital, Breda, The Netherlands.

Autosomal Dominant Epilepsy Syndrome Linked to 2p11

January 2002

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12 Reads

J. Gordon Millichap

A newly recognized autosomal dominant epilepsy syndrome with linkage to chromosome 2p11.1-q12.2 is described in an Italian pedigree of 8 patients reported from the Neurosciences Unit, Institute of Child Health and Great Ormond Street Hospital for Children, London, UK.

Phenotype of Mitochondrial DNA 3243A > G Mutation

October 2007

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17 Reads

J. Gordon Millichap

The prevalence and common clinical manifestations of the mitochondrial DNA 3243A > G mutation in children in a defined population in Finland were studied at the Universities of Oulu and Turku and other centers.

5,10-Methylenetetrahydrofolate Reductase Deficiency and Myoclonic Epilepsy

September 2014

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10 Reads

J. Gordon Millichap

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John J Millichap

Investigators from the Children's Hospital of Philadelphia, PA, and McGill University, Montreal, Quebec, CA, report an adolescent learning-disabled girl who presented at age 14 years with an epilepsy syndrome initially diagnosed as juvenile myoclonic epilepsy.

Role of HHV-6B Infection in Mesial Temporal Lobe Epilepsy

June 2015

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37 Reads

John J Millichap

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J. Gordon Millichap

Investigators from Fujita Health University, Toyoake, and National Epilepsy Center, Shizuoka, Japan, studied the pathogenic role of HHV-6B in patients with mesial temporal lobe epilepsy (MTLE). Of 75 intractable MTLE patients, 52 had mesial temporal sclerosis (MTS) and 23 were non-MTS patients.

Enterovirus 71 Brainstem Encephalitis and Cognitive and Motor Deficits

December 2006

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19 Reads

J. Gordon Millichap

Follow-up studies were conducted in 63 previously healthy children with enterovirus 71 brainstem encephalitis (49 stage II, 7 stage Ilia, and 7 stage Illb) at National Cheng Kung University Hospital, Tainan, Taiwan.

Neurologic Complications of Enterovirus 71 Infection

October 1999

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8 Reads

J. Gordon Millichap

The neurologic complications associated with the 1998 Taiwan enterovirus 71 epidemic are reported from National Cheng Kung University, Tainan; Chang Gung Children’s Hospital, Kaohsiung; and National Defense Medical Center, Taipei, Taiwan.

Enterovirus 71 CNS Infection and ADHD

September 2008

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30 Reads

J. Gordon Millichap

ADHD symptoms as long-term sequelae of virus-confirmed enterovirus 71 infection were evaluated in 86 children, aged 4 to 16 years, followed at National Taiwan University Hospital, Taipei, and Chang Gung Children’s Hospital, Taoyuan, Taiwan.

Enterovirus 71 Meningoencephalitis

February 1999

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8 Reads

J. Gordon Millichap

Seven cases of encephalitis and 5 of aseptic meningitis caused by an outbreak of enterovirus 71 (EV71) during the summer of 1997 are reported from the Otsu Municipal Hospital, Shiga, Japan.