Wiley

International Journal of Eating Disorders

Published by Wiley

Online ISSN: 1098-108X

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Print ISSN: 0276-3478

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Top-read articles

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Effects of Childhood Emotional Abuse on Treatment Outcome in Adolescent Inpatients With Anorexia Nervosa

June 2025

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Objective Although childhood maltreatment, especially emotional abuse, is strongly linked to the psychopathology of anorexia nervosa (AN), the impact of such a traumatic experience on treatment outcome is not clear. This study aimed to explore how emotional abuse affects change in psychopathology during treatment. Method Adolescents with AN (n = 331) completed the Childhood Trauma Questionnaire at admission to inpatient treatment and the Eating Disorder Inventory‐2, Patient Health Questionnaire‐9, Patient Health Questionnaire‐15, and Generalized Anxiety Disorder‐7 both at admission and at discharge. Relationships of emotional abuse with body mass index (BMI) and questionnaire scores at admission and at discharge were examined with percentage bend correlation coefficients. Changes in BMI and questionnaire scores from admission to discharge and whether these changes were moderated by emotional abuse were tested with robust mixed models. Results Higher emotional abuse scores related to higher eating disorder, depressive, anxiety, and somatic symptoms but not to BMI at admission and at discharge. BMI increased and eating disorder, depressive, anxiety, and somatic symptoms decreased from admission to discharge but these changes were not moderated by emotional abuse scores. Discussion Emotional abuse did not affect treatment response during hospitalization for AN, but it was associated with heightened eating and general psychological symptom severity at both hospital admission and discharge. Clinicians are advised to investigate a history of emotional abuse in adolescents with AN and to consider emotional abuse not as a predictor of treatment resistance, but as a psychological scar that persists regardless of symptom severity.

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Dynamic structural equation model (DSEM) of overvaluation of shape and weight (OSW), dietary restraint (DR), and objective binge‐eating episodes (OBEs), adapted from Hamaker et al. (Hamaker et al. 2021). The left panel presents the decomposition into within‐patient and between‐patient components. The top right panel shows the within‐patient level model, including the random effects marked as black dots, and the bottom right panel shows the between‐patient level model.
Mean values of overvaluation of shape and weight (OSW), dietary restraint (DR), and objective binge‐eating episodes (OBEs) over 24 weeks of cognitive‐behavioral therapy. Data from weeks with < 5 patients were excluded. Missing data were handled using the last observation carried forward (LOCF) method. Error bars indicate the standard error of the mean.
Mechanisms of Change in Cognitive‐Behavioral Therapy for Adults With Binge‐Eating Disorder: A Dynamic Structural Equation Modeling Approach

May 2025

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32 Reads

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1 Citation

Aims and scope


With a mission to advance the scientific knowledge needed for understanding, treating, and preventing eating disorders, the International Journal of Eating Disorders publishes to an international readership of health professionals, clinicians and scientists. We also draw the interest of patient groups, advocates and mainstream media outlets. We welcome state-of-the-art scientific research on theory, methodology, etiology, clinical practice, and policy as well as contributions that facilitate scholarly critique and discussion of science and practice in the field.

Recent articles


Disordered Eating and Intentional Insulin Restriction Among Young Adults With Type 1 Diabetes: An Examination of Diabetes Distress and Appearance‐Related Perceptions as Correlates
  • Article
  • Publisher preview available

June 2025

Jayden M. Hartlaub

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Erin M. Hill

Purpose/Objectives Individuals with type 1 diabetes engage in disordered eating behaviors at twice the rate of the general population, including intentional insulin restriction to avoid weight gain. The present study examined possible correlates (diabetes distress, appearance‐related perceptions) of dietary restraint, diabetes‐specific disordered eating, and intentional insulin restriction. Method Participants were 199 individuals with type 1 diabetes aged 18–40 years recruited via Prolific. They completed a Qualtrics survey measuring diabetes distress, weight esteem, physical appearance comparisons on social media (PACSM) and an item focused on perceptions of BMI as an indicator of health. Participants also completed questionnaires focused on disordered eating—diabetes‐specific disordered eating and dietary restraint, as well as an item capturing intentional insulin restriction. Results Diabetes distress emerged as a correlate of all three indicator variables and was the strongest correlate of diabetes‐specific disordered eating and intentional insulin restriction. PACSM was the strongest correlate for dietary restraint, and weight esteem was significant in both disordered eating models (diabetes‐specific, dietary restraint). Discussion Diabetes distress and appearance‐related variables (weight esteem, PACSM) explained unique variance in disordered eating among young adults with type 1 diabetes. Future research should examine these variables in clinical settings.


Conceptual model. Abbreviations: T1, time 1; T2, time 2; T3, time 3; T4, time 4.
Longitudinal Associations of Childhood Emotional Maltreatment With Disordered Eating Behaviors: Linking Mechanisms of Repetitive Negative Thinking and Body Dissatisfaction

Qinglu Wu

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Peilian Chi

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Chuqian Chen

Objective The relationship between childhood emotional maltreatment and disordered eating behaviors (DEBs) has been well documented. However, the mechanisms that link these associations are underexplored, and most studies have focused on the roles of emotion‐related symptoms or processes. Based on the stress process model, the present study investigated how childhood emotional maltreatment exerts long‐term effects on DEBs in adulthood by examining the mediating roles of repetitive negative thinking (RNT) and body dissatisfaction. Method Four‐wave and self‐report survey data were collected from 668 Chinese young adults (66.8% female, Mage = 19.96 years, SD = 1.25) with a 6‐month between‐wave interval. Data were collected on childhood emotional maltreatment (i.e., emotional abuse and neglect), RNT (i.e., past‐oriented: rumination; future‐oriented: worry), body dissatisfaction, loss of control eating, and restrained eating. Results Childhood emotional abuse recalled at T1 was positively associated with loss of control eating at T4 via worry at T2 and with restrained eating at T4 via a serial mediating pathway from worry at T2 to body dissatisfaction at T3. No significant indirect effects emerged for childhood emotional neglect and rumination or indirect pathways involving body dissatisfaction alone. Discussion Negative cognitive processes toward the future and body dissatisfaction are important mechanisms in the associations of early emotional threat with DEBs. The type of childhood maltreatment and RNT are important in this transmission. Interventions aimed at reducing loss of control over eating and restrained eating could work on decreasing worry and alleviating body dissatisfaction, particularly for people with experiences of early emotional threat.


PRISMA flowchart of study selection.
Quality assessment using the Cochrane risk of bias tool.
Smartphone Applications for Eating Disorders: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Objective Given the rising prevalence of eating disorders (EDs), smartphone applications (apps) have received growing clinical attention, but their overall effectiveness remains undetermined. This study aimed to conduct a meta‐analysis of randomized controlled trials (RCTs) evaluating the efficacy of app interventions for EDs and to identify the psychological approaches featured in these interventions. Method The online databases SCOPUS, PubMed, and EBSCO were searched for trials published up to February 2025. This review followed PRISMA guidelines, and meta‐analyses were conducted using post‐intervention assessment data. Pooled effect sizes were calculated with 95% confidence intervals. Results Seventeen studies met the inclusion criteria, and 14 were included in the quantitative synthesis. Trials involving not formally diagnosed samples indicated that app‐based interventions were more efficacious than controls in reducing global levels of ED symptomatology, shape and weight concerns, dietary restraint, binge eating, and compensatory behaviors. No significant effects were found for body dissatisfaction/disturbance or drive for thinness. Self‐help interventions showed generally comparable improvements. In formally diagnosed samples, only objective binge eating was analyzed, with a medium effect observed when the app was incorporated into guided self‐help. The use of an adjunctive app was not shown to have benefit above and beyond traditional therapy. Most interventions were based on cognitive‐behavioral therapy principles. Discussion This review supports the efficacy of app‐based interventions in reducing key ED symptoms, particularly within the binge‐eating spectrum and among at‐risk individuals. Nonetheless, given the limited number of studies, further research with high‐quality RCTs, larger samples, and proper follow‐ups is needed.


Steps for best practices in item writing and scale development: An iterative process. As represented by the arrows, item writing and scale development are iterative processes. This figure was adapted from Clark and Watson's (2019) detailed guide for item writing and scale development. The above steps were followed to develop the IDAS and IDAS‐II.
From Consensus to Innovation: Advancing the Science of Eating‐Disorder Measurement

This commentary is a response to the article written by Reilly et al. (2025). The authors discuss the Eating Disorder Examination (EDE), asserting that critiques of the EDE reflect a larger assessment issue within the field. Their solutions were centered on establishing consensus regarding assessment goals, guidelines, and decision‐making frameworks. We propose that to move the field forward, assessment efforts strive for the ambitious and necessary goal of creating an omnibus tool that comprehensively captures the full spectrum of eating‐disorder presentations. Our arguments are grounded in three key points: (1) there is a pressing need to apply evidence‐based approaches in scale development; (2) the EDE's widespread use does not warrant its continued endorsement; and (3) it is essential for the field to critically examine the consequences of continued reliance on the EDE. We provide illustrative examples from other fields in which newer measures were developed and widely adopted, leading to improvements in those fields. We call on the field to embrace curiosity and continuous learning in the pursuit of more rigorous measurement. Advancing scale development practices will enhance our understanding of what constitutes eating‐disorder psychopathology and also improve quality‐of‐care.


Analysis flowchart of text mining on free‐text responses to weight loss and compensatory behaviors questions from participants of the GLAD Study and EDGI UK.
The identified themes from respondents' weight loss behaviors.
Co‐occurrence network of weight loss behaviors identified in the study. Each node represents a specific behavior, with the node's size corresponding to the frequency of that behavior's occurrence. Edges (lines) between nodes indicate instances where two behaviors co‐occurred, with the thickness of each edge reflecting the strength of the co‐occurrence. This visualization provides insights into how different weight loss behaviors are interrelated, highlighting patterns of behavior combinations among participants.
Frequencies of weight loss behaviors by eating disorder: Anorexia nervosa (across subtypes; n = 691), bulimia nervosa (n = 903), and binge‐eating disorder (n = 81). If the bar is not displayed, the weight loss behavior was not endorsed.
Demographic characteristics of the GLAD and EDGI UK sample that answered the ED100K.V3 (n = 1675).
Beyond the Diagnostic Checklist: A Large‐Scale Analysis of Under‐Recognized Weight Loss Behaviors in Individuals With Eating Disorders

June 2025

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13 Reads

Objective This study aimed to explore the diverse range of weight loss behaviors that extend beyond traditional diagnostic criteria, highlighting the variability in symptom presentation. Method We text mined free‐text responses from 1675 participants with anorexia nervosa, bulimia nervosa, or binge‐eating disorder in the Genetic Links to Anxiety and Depression (GLAD) Study and the Eating Disorders Genetics Initiative UK (EDGI UK). In secondary analyses, we investigated differences by eating disorder and gender. Results Frequently endorsed behaviors included structured diets (619 endorsements) and calorie counting (422 endorsements), but also less commonly considered behaviors like compression garments (147 endorsements) and self‐harm (88 endorsements). We identified four overarching themes: restriction‐based approaches, medical intervention, body manipulation, and food avoidance. The most frequently reported weight loss behaviors and resultant themes did not differ among eating disorders or genders, closely resembling those in the broader sample. Notably, 81 participants with binge‐eating disorder, which typically lacks the endorsement of recurrent compensatory behaviors, reported weight loss and compensatory behaviors. Discussion Our findings identify a crucial gap in current diagnostic assessments, which may hamper recognition and lead to underdiagnosis of eating disorders. By incorporating our insights into an inclusive assessment process that expects and accommodates novel behaviors, clinicians could capture a broader spectrum of behaviors, thus improving diagnostic accuracy. However, our sample homogeneity implies the need for more diverse samples. Our study contributes essential insights for enhancing diagnostic criteria.


Flowchart of study sample for AN‐OCD analyses. Note: Individuals were excluded if their subsequent disorder occurred within 2 years of the initial disorder. Parallel follow‐up of the study population was conducted for subsequent anxiety disorder, to identify unique risk factors for AN‐OCD comorbidity, rather than risk for nonspecific psychiatric comorbidity. AN = anorexia nervosa; OCD = obsessive‐compulsive disorder.
Predictors of Anorexia Nervosa and Obsessive‐Compulsive Disorder Comorbidity and Order of Diagnosis in a Danish National Cohort

June 2025

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9 Reads

Objective Anorexia nervosa (AN) and obsessive‐compulsive disorder (OCD) are highly comorbid; however, limited research has examined etiological pathways specific to individuals with AN developing OCD or individuals with OCD developing AN. This exploratory study aimed to identify factors influencing AN‐OCD comorbidity with a focus on the order of diagnosis. Method Using Danish national registers, 6449 individuals with AN and 9352 individuals with OCD were examined to assess the risk of subsequent OCD and AN. Explored predictors included parental characteristics, birth characteristics, childhood adversity, autoimmune and autoinflammatory diseases, psychiatric disorders, and prescriptions. Hazard ratios (HR) were calculated using Cox regression. Parallel analyses were conducted for the risk of subsequent anxiety disorder to determine predictors unique to AN‐OCD comorbidity. Results Among individuals with AN, high birth weight (HR = 3.06) was uniquely associated with increased risk of subsequent OCD. For individuals with OCD, a history of other eating disorders (HR = 7.47) was associated with elevated risk of developing AN, whereas anxiety disorders in first‐degree (HR = 0.32) and female first‐degree relatives (HR = 0.22) were uniquely protective against AN. Discussion These exploratory findings suggest that distinct pathways may be involved in the order of onset for AN‐OCD comorbidity. Specifically, for individuals with AN who subsequently developed OCD, high birth weight appeared to increase risk, whereas for individuals with OCD who later developed AN, familial anxiety disorders seemed to play a protective role. Findings could inform early screening and prevention efforts for individuals with AN at high risk for OCD, and vice versa.


Predictive Validity of Maladaptive Exercise Definitions: A 10‐Year Longitudinal Cohort Study

Objective Prior efforts to define maladaptive exercise indicate that compensatory and compulsive features and exercising for appearance are associated with disordered eating in cross‐sectional studies. However, the predictive validity of these definitions in adults requires examination. This study employs a 10‐year longitudinal cohort design to evaluate whether these established definitions of maladaptive exercise predict disordered eating and weight‐related outcomes. Methods Men (n = 592) and women (n = 1467) completed surveys of exercise and disordered eating in 2002, and 74% completed surveys at the 10‐year follow‐up. Exercise amount (duration and frequency), compensatory, appearance, and compulsive exercise were tested as prospective predictors of body mass index (BMI), Drive for Thinness, and Bulimia. Results Exercise for appearance prospectively predicted higher BMI, Drive for Thinness, and Bulimia at follow‐up. Compensatory exercise also uniquely predicted higher BMI at follow‐up, and compulsive exercise demonstrated no unique prospective associations with disordered eating or weight‐related outcomes. Discussion The unique effect of appearance exercise highlights the importance of addressing exercise motivations to reduce disordered eating risk. Such work may highlight that exercising for weight control or body definition predicts higher BMI and more disordered eating over the long term. Future studies should employ longitudinal designs, with multiple waves of follow‐up, to examine potential bidirectional influences between maladaptive exercise and disordered eating as well as the long‐term health consequences of maladaptive exercise.


Trial, Error, and Insight: Using the Pilot Study of the HOPE Program to Inform Next Steps for Digital Single‐Session Research for Eating Disorders

June 2025

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2 Reads

Digital single‐session interventions (D‐SSIs) are emerging as promising tools for bridging treatment gaps in youth mental health. Negi and Forbush's recent pilot study introduces “Help for Overcoming Problem Eating” (HOPE), a D‐SSI targeting binge‐spectrum eating disorders in university students. Their findings suggest preliminary acceptability, feasibility, and symptom improvements, contributing to the growing evidence‐base for D‐SSIs in disordered eating. This commentary outlines five key challenges that must be addressed to translate pilot findings into real‐world impact. First, the uptake of D‐SSIs is often low, likely due to help‐seeking barriers and septicism towards this approach. Peer‐led, promotional campaigns may boost engagement of D‐SSIs in young people. Second, despite their brevity, D‐SSI completion is not assured. Strategies such as automated reminders, peer or AI‐guided support, and youth co‐design may improve adherence. Third, economic evaluations are rare but critical for determining whether D‐SSIs offer cost‐effective support within resource‐limited student services. Fourth, trials should examine mechanisms and durability of change, with complementary D‐SSIs offering promising directions. Finally, meaningful integration into care pathways is critical. D‐SSIs may serve as stand‐alone supports, early engagement tools, or components of stepped‐care models. Lack of response could signal the need for intensive care, while successful use may increase openness to further help‐seeking. Addressing these challenges with informative, implementation‐ready trials will be key to realizing the full potential of D‐SSIs in addressing eating disorders in university students and advancing youth mental health care more broadly.


CONSORT flow diagram. Displayed is the patient flow from enrollment to follow‐up, specifying attrition (treatment discontinued or not received: 2/14 per arm, 4/28 total) and from those receiving treatment, early treatment dropout (attendance of < 4 sessions, SmartCBT: 1/13, CBT: 0/12), treatment completion (attendance of ≥ 8 sessions, SmartCBT: 9/13, CBT: 10/12), and assessment completion of the primary efficacy estimate at posttreatment (SmartCBT: 8/13, CBT: 11/12) and follow‐up (SmartCBT: 6/13, CBT: 9/12). CBT, cognitive‐behavioral therapy; SmartCBT, smartphone‐supported CBT.
Acceptance ratings at posttreatment. Displayed are M and SD. Patient evaluation of the utility of the trEATsmart app was determined in the SmartCBT patients for whom a specific trEATsmart module was activated (Regular eating: 7/10, Balanced eating: 7/9, Allow enjoyment: 7/8, Trigger identification: 7/8, Emotion regulation: 7/9, Impulse regulation: 6/8, Positive body image: 4/5, Regular physical activity: 6/6, Regular weighing: 7/8). Patient evaluation of the treatment overall, success and long‐term success expectation was assessed in 6, 7, and 7 of 13 SmartCBT patients and in 9, 8, and 8 of 12 CBT patients. CBT, cognitive‐behavioral therapy; SmartCBT, smartphone‐supported CBT.
Smartphone‐Supported Cognitive‐Behavioral Therapy in Binge‐Eating Disorder: An Exploratory Randomized Trial

June 2025

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9 Reads

Objective To assess the feasibility of a smartphone app delivering just‐in‐time adaptive interventions as an adjunct to cognitive‐behavioral therapy (CBT) adapted to binge‐eating disorder (BED), estimate its effects assuming superiority over CBT alone, and document safety and target engagement. Method A single‐center, assessor‐blinded, parallel feasibility study randomized adults aged 18–65 years with full‐syndrome or subthreshold BED to smartphone‐supported CBT (SmartCBT) or standard CBT (DRKS00024597). Both arms received 16 individual 50‐min CBT sessions over 4 months. Assessments were conducted at baseline (T0), midtreatment (T1), posttreatment (T2), and 3‐month follow‐up (T3). Feasibility was determined regarding recruitment, attrition, dropout, adherence, assessment completion, app use, and acceptance. Further, eating disorder symptoms, mental and physical health, weight management behavior, safety, and target engagement (i.e., skill use) were assessed. Results Over a 7‐month recruitment period, 28 of 50 eligible volunteers were included and randomized 1:1 to SmartCBT or CBT. In the modified intent‐to‐treat sample (N = 25; SmartCBT: 13, CBT: 12), the feasibility of SmartCBT was further supported regarding attrition, dropout, adherence, treatment completion, app use, and acceptance; however, assessment completion was moderate. Clinical improvements were found in both arms, but differential results were affected by baseline differences and moderate assessment completion in the SmartCBT arm. Safety was documented, and support for target engagement was found. Conclusions This exploratory study provides evidence for the feasibility of app‐supported CBT for BED. With few procedural refinements, the protocol can be used in a confirmatory randomized‐controlled trial with long‐term follow‐up to evaluate efficacy and determine treatment mechanisms. Trial Registration German Clinical Trials Register, https://www.drks.de, DRKS00024597


PRISMA flow diagram.
Forest plot of binge‐eating disorder diagnosed by clinical interview (DSM‐IV).
Forest plot of binge‐eating disorder diagnosed by clinical interview (DSM‐5).
Forest plot of moderate binge eating measured using the Binge Eating Scale (scores 17–26).
Forest plot of severe binge eating measured using the Binge Eating Scale (scores > 25).
The Prevalence of Eating Disorders and Disordered Eating in Adults Seeking Obesity Treatment: A Systematic Review With Meta‐Analyses

Objective To estimate the prevalence of eating disorders and disordered eating in adults seeking obesity treatment. Method Databases, MEDLINE, Embase, and PsycINFO, were searched to 20th March 2025. Studies reporting the prevalence of eating disorders or disordered eating at presentation to obesity treatment in adults (≥ 18 years) with overweight (BMI 25 to < 30 kg/m²) or obesity (BMI ≥ 30 kg/m²), with ≥ 325 participants to ensure a representative sample, were included. A random‐effects model was used to pool prevalence estimates of eating disorders and disordered eating. Results 85 studies were included (n = 94,295, 75.9% female, median (IQR) age 44 (5) years, BMI 46 (10) kg/m²). When assessed by clinical interview, the pooled prevalence of binge‐eating disorder (Diagnostic and Statistical Manual of Mental Disorders‐5) was 14% (95% CI: 7 to 22, prediction interval [PI]%: 0 to 43, k = 10, n = 8534), and bulimia nervosa 1% (95% CI: 0 to 1, PI%: 0 to 2, k = 9, n = 9448, τ² = 0). When assessed using the Binge Eating Scale, the prevalence of self‐reported moderate severity binge eating was 26% (95% CI: 23 to 28, PI%: 18 to 33, k = 12, n = 8113, τ² = 0.001) and severe binge eating was 12% (95% CI: 8 to 16, PI%: 0 to 31, k = 18, n = 12,136, τ² = 0.01). Discussion Obesity and eating disorders or disordered eating do co‐occur. There was variability between studies and between the prevalence of eating disorders and disordered eating in adults presenting for obesity treatment. It is critical that clinicians are well resourced to effectively identify individuals with eating disorders and disordered eating and provide appropriate treatment pathways.


Consort diagram.
Graphical representations of the primary outcomes at each timepoint (raw means/percentages with standard errors).
Randomized Controlled Trial of Weight Management Versus Weight Management With Concurrent Cognitive‐Behavioral Therapy for Binge‐Eating Disorder in US Veterans With High Weight

Objective To determine the effectiveness of adding a brief psychological eating‐disorder treatment (CBT) to weight management for addressing DSM‐5 binge‐eating disorder (BED) in US military Veterans with high weight. Method One hundred and nine Veterans, with DSM‐5 BED, seeking weight management services were randomly assigned to VA's Weight Management Program (MOVE!), or MOVE! plus a brief, clinician‐led cognitive‐behavioral therapy (MOVE! + CBT). Primary (eating disorder psychopathology and binge eating), secondary (mental health, quality of life, and eating‐ and appearance‐related), and exploratory (weight) outcomes were analyzed with mixed‐effects models for four timepoints (baseline, 3‐month [post‐treatment], and 9‐ and 15‐month follow‐ups). Results MOVE! + CBT reported significantly less overall eating disorder psychopathology compared to MOVE! at all post‐randomization timepoints: difference at 3 months −0.18 (−0.3, −0.06, p = 0.003), 9 months −0.15 (−0.3, 0, p = 0.05), and 15 months −0.27 (−0.42, −0.12, p < 0.001). There were no differences between groups in binge‐eating frequency. MOVE! + CBT remission rates were 28% at 3 months, 42% at 9 months, and 27% at 15 months. MOVE! remission rates were 22% at 3 months, 26% at 9 months, and 20% at 15 months. MOVE! + CBT was superior at post‐treatment through 15 months on eating‐, weight‐, and shape‐related (p's < 0.05), but few other, secondary outcomes. A 5% weight loss ranged from 26% to 38% for MOVE! + CBT, and 17% to 33% for MOVE!. Discussion Weight management alone and with concurrent CBT resulted in significant improvements in BED. The addition of CBT enhanced some specific outcomes but not weight loss. Findings provide evidence‐based clinical guidance and population‐level impact for addressing BED in the context of high weight, especially among Veteran populations. Trial Registration: Clinical Trial Registry Number: NCT03234881(Weight Loss Treatment for Veterans with Binge Eating)


Study selection flow chart.
Evidence of Altered Biobehavioral Threat Processes in Adolescents With Eating Disorders: A Scoping Review

Objective Etiological models of eating disorders (EDs) suggest there is considerable overlap between anxiety and EDs. In particular, shared clinical features across these psychiatric diagnoses suggest that common threat processes (i.e., changes in affect, cognition, and physiology, or behavior in response to a feared stimulus) underlie their maintenance. Compared to anxiety disorders, however, less is known about the neurobiological bases of threat that may give rise to and maintain ED symptoms, particularly among adolescents. Addressing this knowledge gap will aid in informing future research and interventional efforts. Methods We searched four online databases to review studies published through March 2025 comprising all potential types of assessment of biobehavioral activity associated with threat (e.g., neuroimaging, skin conductance) in clinical samples of adolescents with EDs. Results From 2546 articles identified, N = 19 studies met inclusion criteria. A majority of investigations employed functional neuroimaging to study adolescent girls with anorexia nervosa, compared with age‐matched controls. We classified and synthesized evidence within categories of non‐ED‐specific threat (harm avoidance) or ED‐specific threat (bodily‐ or food‐related threat, or their combination). Most studies demonstrated altered ED‐specific threat processing in adolescent girls with anorexia nervosa compared to controls, as well as associations between neural threat response and ED symptomology. The study focused on non‐ED‐specific threat found no noted differences in threat response in cases versus controls. Discussion Given the apparent relevance of threat processing in EDs, future inquiry is needed to resolve remaining questions and yield new insights with clinical relevance across transdiagnostic adolescent ED presentations.


Effects of Childhood Emotional Abuse on Treatment Outcome in Adolescent Inpatients With Anorexia Nervosa

June 2025

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52 Reads

Objective Although childhood maltreatment, especially emotional abuse, is strongly linked to the psychopathology of anorexia nervosa (AN), the impact of such a traumatic experience on treatment outcome is not clear. This study aimed to explore how emotional abuse affects change in psychopathology during treatment. Method Adolescents with AN (n = 331) completed the Childhood Trauma Questionnaire at admission to inpatient treatment and the Eating Disorder Inventory‐2, Patient Health Questionnaire‐9, Patient Health Questionnaire‐15, and Generalized Anxiety Disorder‐7 both at admission and at discharge. Relationships of emotional abuse with body mass index (BMI) and questionnaire scores at admission and at discharge were examined with percentage bend correlation coefficients. Changes in BMI and questionnaire scores from admission to discharge and whether these changes were moderated by emotional abuse were tested with robust mixed models. Results Higher emotional abuse scores related to higher eating disorder, depressive, anxiety, and somatic symptoms but not to BMI at admission and at discharge. BMI increased and eating disorder, depressive, anxiety, and somatic symptoms decreased from admission to discharge but these changes were not moderated by emotional abuse scores. Discussion Emotional abuse did not affect treatment response during hospitalization for AN, but it was associated with heightened eating and general psychological symptom severity at both hospital admission and discharge. Clinicians are advised to investigate a history of emotional abuse in adolescents with AN and to consider emotional abuse not as a predictor of treatment resistance, but as a psychological scar that persists regardless of symptom severity.


Contrasting weight trajectories, according to weight variability and net change. Figure 1A shows three different trajectories from Weeks 0 through 4. All patients have the same starting weight (119 lbs), and all gain 5 lbs by their fourth session. However, they accomplish their weight gain along varying weekly changes: in the left panel, the patient steadily gains 1.25 lb/wk.; in the middle panel, the patient alternates between gaining 3.5 lbs and losing 1 lb; and in the right panel, the patient gains 5 lbs in the first week, while plateauing from Weeks 2 through 4. In contrast, Figure 1B shows the same weight variability (i.e., 0 lbs; datapoints show no deviation from the weight trend line), but with different patterns of net weight change (i.e., weight gain, no weight change, weight loss) from Weeks 0 through 4.
Effects of Early Weight Trends on Residential Treatment Outcomes Among Adolescents With Anorexia Nervosa

Background Weight variability (WV), or daily‐to‐weekly fluctuations in weight, associates with increased eating pathology in adults with bulimia nervosa and greater weight gain across the developmental span in healthy controls, but few studies have explored these relations in adolescents with anorexia nervosa (AN). Given the importance of early weight gain during treatment for AN prognosis, WV could impact outcomes via effects on weight trends and related psychopathology. The current study examined whether WV and the slope of weight change predict eating disorder symptoms at the end of treatment (EOT) among adolescents with AN. Method Adolescents with AN (N = 284) receiving residential treatment completed the Eating Disorder Examination Questionnaire (EDE‐Q) at admission and EOT. WV was calculated using the root‐mean‐squared‐error of daily weights over the first 14 days of treatment. Linear regressions examined the effect of WV, slope of weight change over 14 days, and their interaction on percent expected body weight (%EBW) and EDE‐Q scores at EOT. Results WV positively predicted EDE‐Q Global Score (p = 0.033, sr² = 0.01), Shape Concern (p = 0.026, sr² = 0.01), and Weight Concern (p = 0.008, sr² = 0.02) at EOT. Neither WV nor the slope of weight change predicted %EBW at EOT (ps > 0.05). The slope of weight change did not predict EDE‐Q, nor did it moderate the relation between WV and any outcomes (ps > 0.05). Conclusions Patients who experience greater weight fluctuations early in treatment may be more susceptible to elevated psychopathology at discharge. In light of few significant effects and small effect sizes, more research is needed to determine the putative role of early weight trends in adolescent AN outcomes.


EDE and EDE‐Q: A Call for Field Wide International Collaboration When Revisiting a Classic, Commentary on Reilly et al. (2025)

In their 2025 article in the International Journal of Eating Disorders, Reilly, Gorrell, Chapa, Drury, Stalvey, Goldschmidt, and le Grange examine the widespread use of the Eating Disorder Examination (EDE) and its self‐report version, the Eating Disorder Examination‐Questionnaire (EDE‐Q), in assessing eating disorder symptoms. While acknowledging the popularity of these instruments, the authors highlight important limitations—including restricted scope, psychometric shortcomings, and practical challenges such as inconsistent scoring practices and limited applicability across diverse populations. Rather than advocating for the development of entirely new measures, the authors propose building a field‐wide consensus to refine existing tools and promote their broader and more consistent use. Reilly et al.'s paper is a timely and valuable contribution to ongoing conversations about assessment practices in the field. In this commentary, we extend their perspective by drawing on previous experiences in the field that support their call to action and suggest that future consensus efforts should built on international experience and collaboration, and ensure that lived experience voices are integral to the process.


The Potential of Small Effects at the Right Time, on a Large Scale: Commentary on Linardon et al. (2025)

The meta‐analysis of self‐help intervention for eating disorders (ED) by Linardon and colleagues showed significant, albeit small, effects favoring self‐help over the control condition on depression, anxiety, distress, and self‐esteem. Despite modest effect sizes, pure self‐help offers the potential for high accessibility at low cost, which may lead to a meaningful impact on public health in terms of mental health symptoms that are often co‐occurring with ED. There are opportunities to present and package pure self‐help in more creative ways than what is currently available (e.g., by integrating brief instructional and experiential videos, infographics, storytelling, and compelling patient narratives). To fully harness the potential of pure self‐help, disruptive innovations are necessary in both the packaging and delivery methods. These innovations can help to accommodate various needs, learning styles, and preferred delivery formats. A consortium dedicated to pure self‐help for symptoms of ED and its prevention can play a vital role in testing, delivering, collecting big data, understanding moderators of outcomes, and facilitating adaptation and further development, thereby improving access to these interventions and leading to better mental health.


Moderating effect of threshold DSO symptoms and CPTSD at baseline on anxiety and depressive symptoms. CPTSD, complex post‐traumatic stress disorder; DSO, disturbances in self‐organization; DSO‐t, above DSO symptom threshold. Time 1, admission; 2, week 4 of treatment; 3, discharge; 4, 6‐months post‐discharge. Error bars represent standard error.
Moderating effect of threshold PTSD symptoms at baseline. PTSD, post‐traumatic stress disorder; PTSD‐t, above threshold for PTSD symptoms at baseline. Time 1, admission; 2, week 4 of treatment; 3, discharge; 4, 6‐months post‐discharge. Error bars represent standard error.
PTSD and Complex PTSD in Residential Treatment for Eating Disorders: Moderating Effects on Symptom Severity and Outcome Trajectory

May 2025

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30 Reads

Objective Eating disorders (EDs) and symptoms of trauma commonly co‐occur, yet research is limited on how trauma affects ED treatment outcomes. This is particularly true for complex post‐traumatic stress disorder (CPTSD). Differentiating between the treatment impacts of PTSD and CPTSD (which includes both PTSD symptoms and disturbances in self‐organization [DSO]) may help ED providers address this common comorbidity. Method The current study included 95 women (Mage = 26 years) with EDs (largely anorexia nervosa) who received residential treatment (M = 81 days). Participants completed measures of ED symptoms, anxiety, depression, body mass index (BMI), ED‐specific health‐related quality‐of‐life (ED‐HRQoL) impairment, functional disability, and trauma symptoms at admission, week 4 of treatment, discharge, and 6 months post‐discharge. Results All outcomes except BMI were more severe at admission and week 4 of treatment for individuals with comorbid trauma (based on probable CPTSD or exceeding the clinical threshold for PTSD and DSO symptom domains); however, these differences resolved by discharge and remained non‐significant at follow‐up. Some forms of comorbid trauma moderated outcome trajectories for anxiety, depression, and disability (but not ED symptoms), such that individuals with comorbid trauma showed slower improvement early in treatment, steeper improvement later in treatment, and greater resurgence after discharge. Discussion These findings highlight that PTSD and CPTSD symptom domains may be associated with more severe ED outcomes early in residential treatment that resolve by discharge, and may predict differential treatment response for secondary outcomes. Implications are discussed for clinical assessment and treatment of comorbid trauma‐related disorders in residential care. Trial Registration The study was prospectively registered on the Australian and New Zealand Clinical Trials Registry in November 2021, registration number ACTRN12621001651875


UP‐EE flow diagram of participants.
Adapting Barlow's Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Overweight Adults: A Nonrandomized Controlled Feasibility Study

Objective To evaluate the feasibility and potential effectiveness of the Unified Protocol for Emotional Eating (UP‐EE) in a group format. Method Fifty‐seven participants exhibiting high to severe emotional eating (EE) were assigned to an 8‐week group intervention or to a control group receiving treatment as usual (TAU). EE (measured with the Dutch Eating Behavior Questionnaire) was the primary outcome, while state anxiety (State–Trait Anxiety Inventory [STAI‐S]), depression (Beck Depression Inventory [BDI‐II]) and perceived stress (Perceived Stress Scale [PSS‐14]) were the secondary measures, assessed at baseline and post‐intervention, or 8 weeks later in the control group. Satisfaction was measured via the Client Satisfaction Questionnaire (CSQ‐8). Effectiveness was estimated using a linear mixed‐effects model. Results The UP‐EE received positive feedback and achieved an acceptable treatment retention. There were no significant differences regarding sociodemographic and clinical characteristics between groups. While both groups were not significantly different at the end of the intervention, the waitlist group worsened in anxiety, depression, and perceived stress, and showed only a slight improvement in EE. In contrast, the intervention group showed significant improvements across these variables, with a sharper decrease in EE. Results were consistent across both per‐protocol and intention‐to‐treat analyses. Conclusions A group UP‐EE intervention is a feasible intervention. Future research should focus on a larger sample with a randomized controlled trial design and utilize measures of disordered eating to more clearly identify the superiority of the intervention over a comparison condition.


“If There Are Restrictions Within the Restrictions, That's When You Can Probably Get Concerned”: Key Indicators for Untying Vegetarianism and Veganism From Eating Disorder Pathology

Objective Changes in eating patterns and/or food exclusion strategies, including the uptake of vegetarianism and veganism, may reflect disordered behaviors and attitudes in people with eating disorders. For this reason, health professionals often attempt to assess whether a client's vegetarianism or veganism is tied to, or driven by, their eating disorder. Yet this may be difficult considering a lack of formally recognized guidelines for the treatment of vegetarians and vegans with an eating disorder, meaning that often a one‐size‐fits‐all approach to treating these groups is employed. This study aimed to integrate lived eating disorder perspectives to qualitatively inform indicators of potential pathological vegetarian or vegan adherence in people with an eating disorder. Method Seventeen participants (aged 19–48, 76% [n = 13] female, 47.06% [n = 8] vegetarian) with a history of receiving eating disorder treatment were recruited. Results Five themes were identified: (1) Timing matters, (2) Explore motivations for dietary adherence, (3) Fear reaction causes for concern, (4) Flexibility within vegetarianism or veganism, and (5) Hold space for eating disorder deception. Discussion Our findings demonstrate several key indicators that may be useful areas of discussion in clinical practice when working with vegetarian and vegan clients. Being able to potentially quantify genuine vegetarian or vegan adherence from eating disorder‐driven behaviors and attitudes provides a valuable stepping stone to the future development of clinical guidelines for the treatment of people adhering to these dietary groups.


Ecological Momentary Assessment in Eating Disorders Research: A Qualitative Examination of Participant Experience and Recommendations for Future Studies

May 2025

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23 Reads

Objective Ecological momentary assessment (EMA) is a widely‐used research method for investigating temporal relationships among eating disorder (ED) symptoms. Though EMA has many methodological advantages (e.g., reducing retrospective recall bias), little is known about the experience and effects of participating in this type of study from the perspective of individuals with EDs. The present study aimed to examine the experience of participants with EDs after completing an EMA study, with the goal of elucidating potential positive and negative effects of EMA methodology. Method A heterogeneous sample of participants with EDs (N = 192) completed clinical interviews, questionnaires, and an EMA protocol (five surveys/day for 14 days). A subsample of these participants (n = 16) completed a qualitative interview exploring their experience participating in the study. A reflexive thematic analysis was conducted using Nvivo software. Results The following themes were identified: (1) Self‐awareness, mindfulness, and reflection; (2) Behavioral change; (3) Rewarding aspects of the study; (4) Challenging aspects of the study; (5) Study design (including facilitators and barriers to participating); and (6) Suggestions for future studies. Discussion Although participants reported some challenging aspects of the study, most described their experience as positive (or at least neutral), and many noted direct benefits of participating. Future EMA research may benefit from integrating the perspectives of those with lived experience into study design, potentially reducing participant burden, improving the quantity and quality of data collected, and increasing benefits for participants.


Commentary on "Next Steps in Use of the Eating Disorder Examination and Related Eating Disorder Assessments: A Call for Consensus" by Reilly et al

May 2025

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16 Reads

The purpose of this Commentary is to expand upon Reilly et al. 2025's critique of the Eating Disorder Examination (EDE) around a dialectic of its major strengths and its limitations. Although notable strengths of the EDE are its diagnostic case identification and detailed assessment of phenomenology, its resource intensity (training and administration) may explain why researchers and clinicians often prefer to use the EDE‐Q—the self‐report version of the EDE. An example of this is in the development of a national eating disorder assessment package for residential care in Australia, where the EDE‐Q (not the EDE) was recommended by a committee of eating disorder experts advising the Federal Government, and subsequently the EDE‐Q was used by researchers in the clinical evaluation of the first Australian residential program. The present and future need for multidimensional assessments beyond symptoms is presented. A proposal for a global consensus on harmonization of constructs in eating disorder assessment, matching a repertoire of relevant instruments suited to diverse times and places, is suggested.


Weight‐related (in yellow) and non‐weight‐related (in blue) areas of interest.
Visual depiction of the virtual setting and the virtual body.
Self‐Disgust, Body‐Related Attentional Bias and Body Dissatisfaction: A Virtual Reality and Eye‐Tracking Exploration

May 2025

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27 Reads

Objective This study examines the relationships between self‐disgust, body dissatisfaction (BD), and attentional biases (AB) toward weight‐related body areas, exploring whether self‐disgust predicts attentional avoidance and moderates the relationship between BD and AB. Method Using virtual reality and eye‐tracking technology, 78 female students viewed their virtual bodies in a mirror to assess gaze patterns as an indicator of attentional bias. Results BD was positively associated with both AB and self‐disgust. Contrary to expectations, self‐disgust correlated with increased attention to weight‐related areas rather than avoidance and did not moderate the BD–AB relationship. Discussion These findings suggest that self‐disgust may reinforce attention toward weight‐related areas, contributing to negative body image. Future research should explore these mechanisms in clinical populations to inform targeted interventions.


Integrating Artificial Intelligence and Smartphone Technology to Enhance Personalized Assessment and Treatment for Eating Disorders

May 2025

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27 Reads

Objective Smartphone technology presents a promising path toward expanding access to evidence‐based eating disorder assessment and treatment. Despite rapid technological advances, research has yet to harness these systems in ways that make personalized digital health care a clinical reality. In this forum, we review extant research testing smartphone intervention and monitoring tools for eating disorders and explore innovative ways integrating this technology with AI can enhance assessment, symptom detection, and intervention efforts. Method We highlight three capabilities of smartphones that hold promise for delivering personalized and maximally effective digital health tools: (1) passive sensing and digital phenotyping; (2) natural language processing of reflections from in‐app homework tasks; and (3) closed‐loop adaptive interventions. We discuss how these capabilities can augment current assessment and treatment efforts and draw on literature from other fields to inform research questions for the eating disorder field. Results Evidence from other fields demonstrates the feasibility of constructing data‐driven models from smartphone sensor data and textual input from in‐app CBT activities to predict clinical outcomes. These models may inform closed‐loop interventions, enabling apps to deliver timely, personalized support in response to real‐time changes in a user's needs. Conclusion The eating disorder field can draw on lessons from other fields to evaluate smartphone technology that leverages AI to enhance personalization. Realizing the potential of these tools will require addressing challenges related to engagement, trust, data governance, and clinical integration. The testable research questions presented here offer a roadmap to guide future large‐scale, collaborative efforts aimed at transforming eating disorder care.


Dynamic structural equation model (DSEM) of overvaluation of shape and weight (OSW), dietary restraint (DR), and objective binge‐eating episodes (OBEs), adapted from Hamaker et al. (Hamaker et al. 2021). The left panel presents the decomposition into within‐patient and between‐patient components. The top right panel shows the within‐patient level model, including the random effects marked as black dots, and the bottom right panel shows the between‐patient level model.
Mean values of overvaluation of shape and weight (OSW), dietary restraint (DR), and objective binge‐eating episodes (OBEs) over 24 weeks of cognitive‐behavioral therapy. Data from weeks with < 5 patients were excluded. Missing data were handled using the last observation carried forward (LOCF) method. Error bars indicate the standard error of the mean.
Mechanisms of Change in Cognitive‐Behavioral Therapy for Adults With Binge‐Eating Disorder: A Dynamic Structural Equation Modeling Approach

May 2025

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32 Reads

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1 Citation

Objective Cognitive‐behavioral therapy (CBT) is the most well‐established treatment for binge‐eating disorder (BED), but the mechanisms of change remain poorly understood. This study investigated in CBT for BED the effects of overvaluation of shape and weight and dietary restraint on subsequent objective binge‐eating episodes (OBEs). Method In a multicenter randomized‐controlled trial, 84 patients diagnosed with full‐ or subsyndromal BED were offered 20 individual sessions of CBT over 4 months. Dynamic structural equation modeling (DSEM) was used to disentangle within‐ and between‐patient associations of overvaluation of shape and weight, dietary restraint, and OBEs. Results Between the first and last week of therapy, there were significant reductions in overvaluation of shape and weight, dietary restraint, and OBEs. DSEM showed significant within‐patient effects of overvaluation of shape and weight on the subsequent number of OBEs. Weeks with lower overvaluation of shape and weight levels were followed by weeks with fewer OBEs. Although no within‐patient effect of dietary restraint on OBEs was found, within‐patient dietary restraint levels positively predicted subsequent overvaluation of shape and weight levels. Discussion The findings suggest that reductions in overvaluation of shape and weight may precede improvements in binge eating during CBT for BED, supporting its role as a potential mechanism of change. While dietary restraint did not show a direct temporal link to binge eating, its association with overvaluation points to a potential indirect role. These results underscore the value of targeting cognitive features of BED in CBT and highlight the need for more temporally sensitive assessments in mechanisms research.


Maze-Out: A Serious Game to Enhance Treatment for Eating Disorders. A Randomized Controlled Trial

May 2025

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42 Reads

Objective This study evaluated the effectiveness of Maze Out, a serious game (SG) codesigned by patients with eating disorders (ED) and clinicians as an adjunct to treatment as usual (TAU) for improving self‐efficacy, self‐image, and engagement in individuals with ED. Effects on ineffectiveness, insecurity, and personal recovery were also examined. Method A randomized controlled trial (RCT) was conducted at 11 centers in Denmark between July 2022 and December 2023. A total of 133 adult participants (≥ 18 years) with a registered ICD‐10 ED diagnosis were randomized (1:1) to receive Maze Out plus TAU or TAU alone for 15 weeks. Assessments were conducted at baseline, 8 and 15 weeks. The primary outcome was self‐efficacy, while the secondary outcomes included self‐image, feelings of ineffectiveness and insecurity, and personal recovery. Data were analyzed using linear mixed‐effects models under both intention‐to‐treat (ITT) and complete‐case approaches. Results ITT analysis revealed no significant differences between the groups on primary or secondary outcomes. Complete‐case analysis, however, showed significant improvements in personal recovery (mean difference 5.81 [95% CI 0.25–11.37]; p = 0.040) and reductions in negative self‐image, including self‐blame (−13.06 [−24.18 to −1.95]; p = 0.021) and self‐neglect (−14.59 [−28.01 to −1.17]; p = 0.033), in the intervention group. Engagement was high, indicating meaningful interaction with the game. Discussion Although no overall effects were found in ITT analyses, improvements in personal recovery and self‐image support the potential of Maze Out as a feasible and acceptable adjunct to TAU. Further research should assess long‐term and subgroup‐specific effects. Trial Registration: ClinicalTrials.gov identifier: NCT05621018, and the protocol was published (Guala, Bikic, Bul, Clinton, Mejdal, et al. 2024).


Journal metrics


4.7 (2023)

Journal Impact Factor™


26%

Acceptance rate


10.0 (2023)

CiteScore™


3 days

Submission to first decision


1.672 (2023)

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$4,300.00 / £2,860.00 / €3,580.00

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