Human Physiology

Published by MAIK Nauka/Interperiodica
Online ISSN: 1608-3164
Print ISSN: 0362-1197
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In this paper the results of investigations of the CSF obtained during pneumoencephalographic examination of patients in the interepisodic period are described. In some cases auras or major fits developed during the procedure. At these times the CSF was collected separately (before and during the fit), so that the dynamics of the amino-acid composition of the CSF could be studied and compared with clinical manifestations in the same patient. In the course of pneumoencephalography from 40 to 80 ml of CSF was withdrawn and it was therefore possible to study the amino-acid composition of the CSF from different levels of the CSF system (the first 20-30 ml from the spinal portion, the second 20-30 ml from the cerebral portion of the CSF system).
 
Disturbances of perception of motion of a subjective acoustic pattern (SAP) arising under the influence of acoustic stimulating motion of sound from the right or left ear toward the midline of the head were investigated in 30 patients with lesions of the left and right temporal lobes of the brain. In a high proportion of patients (57%) marked disturbances of perception of motion of the SAP were observed. These disturbances were manifested as a shift of the point from which motion of the SAP began, the point at which it ended, and, consequently, a decrease in the trajectory of motion of the SAP compared with healthy subjects. In some cases motion of the SAP could not be perceived. The character of the disturbances of perception of motion of the SAP was found to depend on the side of the temporal lobe lesion. In a lesion of the left temporal lobe disturbances of perception of motion of the SAP were observed both on the side of the pathological focus and on the opposite side. In patients with lesions of the right temporal lobe disturbances were observed only on the side contralateral to the pathological focus, whereas perception of motion of the SAP on the side of the lesion was virtually indistinguishable from its perception by healthy subjects.
 
Short auditory evoked potentials recorded in response to stimulation of the contralateral and ipsilateral ear differ from each other in both number and configuration as well as in the parameters of the individual waves. Medium auditory evoked potentials (MAEP) recorded in response to stimulation of the contralateral and ipsilateral ears contained equal number of waves and have the same configuration. The amplitude of MAEP is greater for stimulation of the contralateral ear. Long auditory evoked potentials (LAEP) recorded in response to stimulation of the contralateral ear have a higher amplitude and shorter peak latency than LAEP recorded in response to stimulation of the ipsilateral ear. The degree of bilateral asymmetry of LAEP is roughly the same for acoustic stimuli of different frequencies. LAEP arising in response to nonverbal acoustic stimuli have a higher amplitude and shorter peak latencies in the right hemisphere than the left. Interhemispheric asymmetry of LAEP is more marked during stimulation of the corresponding contralateral ear. The comparatively early and late components of LAEP are characterized by different degrees of bilateral and interhemispheric asymmetry.
 
Top-cited authors
Elena Tomilovskaya
  • RF SSC - Institute of Biomedical Problems of the RAS, Moscow, Russia
Tatyana Kukoba
  • National ESCA and Surface Analysis Center For Biomedical Problems
Liubov Amirova
Daniil Popov
  • Institute of Biomedical Problems of the Russian Academy of Sciences
Olga L Vinogradova
  • Institute of Bio-medical Problems, Russian Academy of Sciences, Moscow, Russia