Neuroscience & Biobehavioral Reviews (NEUROSCI BIOBEHAV R)

Publisher: Elsevier

Journal description

The journal will publish original and significant review articles dealing with all aspects of neuroscience, where the relationship to the study of psychological processes and behavior is clearly established. Conversely, the journal will also publish articles whose primary focus deals with psychological processes and behavior, and which have relevance to one or more aspects of neuroscience. Submissions to the journal are actively encouraged which deal with topics not only in the more traditional areas, but also in the following areas, whenever the reviews bring new insights into brain-behavior relations: neuropsychology cognitive neuroscience brain imaging in vivo monitoring of the brain's electrical and biochemical activities molecular biology genetics neurocomputation Theoretical articles and mini-reviews, for which the scope and literature coverage are more restricted, will also be published. The table of contents for this journal is now available pre-publication, via e-mail, as part of the free ContentsDirect service from Elsevier Science. Please send an e-mail message to for further information about this service.

Journal Impact: 10.12*

*This value is calculated using ResearchGate data and is based on average citation counts from work published in this journal. The data used in the calculation may not be exhaustive.

Journal impact history

2016 Journal impact Available summer 2017
2015 Journal impact 10.12
2014 Journal impact 10.72
2013 Journal impact 11.10
2012 Journal impact 10.51
2011 Journal impact 11.81
2010 Journal impact 6.91
2009 Journal impact 4.91

Journal impact over time

Journal impact

Additional details

Cited half-life 6.40
Immediacy index 1.66
Eigenfactor 0.04
Article influence 3.59
Website Neuroscience & Biobehavioral Reviews website
Other titles Neuroscience and biobehavioral reviews, Neuroscience & biobehavioral reviews
ISSN 1873-7528
OCLC 3552135
Material type Periodical, Internet resource
Document type Journal / Magazine / Newspaper, Internet Resource

Publisher details

This journal may support self-archiving.
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Publications in this journal

  • [Show abstract] [Hide abstract] ABSTRACT: Synaptic connectivity forms the basis for neuronal communication and the storage of information. Experiences and learning of new abilities can drive remodelling of this connectivity and promotes the formation of spine clusters; dendritic segments with a higher spine density. Spines located within these segments are frequently co-activated, undergo different dynamics than synapses located outside of this dendritic compartment and have, in general, a longer lifetime. Several lines of evidence have shown that chemical synapses located close to each other share or compete for intracellular signalling molecules and structural resources. This sharing and competition directly influences spine dynamics. Spines can grow, shrink, increase or decrease the surface expression of receptors, channels and adhesion molecules or remain stable and unchanged over extended periods of time. Here we summarize recent discoveries and provide a closer look at spine clustering, dendritic segment-specific signalling and potential molecular mechanisms underlying associative and heterosynaptic plasticity.
    Article · Sep 2016 · Neuroscience & Biobehavioral Reviews
  • [Show abstract] [Hide abstract] ABSTRACT: Caffeine is consumed by over 80% of U.S. adults. This review examines the effects caffeine has on cognitive and physical function, since most real-world activities require complex decision making, motor processing and movement. Caffeine exerts its effects by blocking adenosine receptors. Following low (∼40mg or ∼0.5 mg·kg(-1)) to moderate (∼300mg or 4 mg·kg(-1)) caffeine doses, alertness, vigilance, attention, reaction time and attention improve, but less consistent effects are observed on memory and higher-order executive function, such as judgement and decision making. Effects on physical performance on a vast array of physical performance metrics such as time-to-exhaustion, time-trial, muscle strength and endurance, and high-intensity sprints typical of team sports are evident following doses that exceed about 200mg (∼3mg·kg(-1)). Many occupations, including military, first responders, transport workers and factory shift workers, require optimal physical and cognitive function to ensure success, workplace safety and productivity. In these circumstances, that may include restricted sleep, repeated administration of caffeine is an effective strategy to maintain physical and cognitive capabilities.
    Article · Sep 2016 · Neuroscience & Biobehavioral Reviews
  • [Show abstract] [Hide abstract] ABSTRACT: This paper describes the biolinguistic approach to language acquisition. We contrast the biolinguistic approach with a usage-based approach. We argue that the biolinguistic approach is superior because it provides more accurate and more extensive generalizations about the properties of human languages, as well as a better account of how children acquire human languages. To distinguish between these accounts, we focus on how child and adult language differ both in sentence production and in sentence understanding. We argue that the observed differences resist explanation using the cognitive mechanisms that are invoked by the usage-based approach. In contrast, the biolinguistic approach explains the qualitative parametric differences between child and adult language. Explaining how child and adult language differ and demonstrating that children perceive unity despite apparent diversity are two of the hallmarks of the biolinguistic approach to language acquisition.
    Article · Sep 2016 · Neuroscience & Biobehavioral Reviews
  • [Show abstract] [Hide abstract] ABSTRACT: Literature on the co-occurrence between Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) is strongly biased by a focus on childhood age. A review of the adolescent and adult literature was made on core and related symptoms of ADHD and ASD. In addition, an empirical approach was used including 17,173 ASD-ADHD symptom ratings from participants aged 0 to 84 years. Results indicate that ASD/ADHD constellations peak during adolescence and are lower in early childhood and old age. We hypothesize that on the border of the expected transition to independent adulthood, ASD and ADHD co-occur most because social adaptation and EF skills matter most. Lower correlations in childhood and older age may be due to more diffuse symptoms reflecting respectively still differentiating and de-differentiating EF functions. We plea for a strong research focus in adolescence which may −after early childhood- be a second crucial time window for catching-up pattern explaining more optimal outcomes. A full lifespan approach into old age.
    Article · Sep 2016 · Neuroscience & Biobehavioral Reviews
  • Gabriele Masi · Annarita Milone · Paola Brovedani · [...] · Pietro Muratori
    [Show abstract] [Hide abstract] ABSTRACT: Disruptive Behavior Disorders (DBDs) are stable and impairing disorders, heterogeneous in presentation, developmental pathways, and treatment needs. Disentangling subtypes according to psychopathological dimensions is helpful for timely diagnoses, precise prognoses and tailored interventions. Psychopathic traits are relevant in subtyping DBDs with severe antisocial and aggressive behaviors. Three psychopathy dimensions have been found: 1) an affective dimension, the callous-unemotional (CU) trait, with lack of empathy and remorse, and with short-lived emotions; 2) an interpersonal dimension, the narcissistic domain, with manipulative abilities, superficial charm, egocentricity and grandiosity; 3) a behavioral dimension, the impulsivity or impulsive-irresponsibility, with irresponsibility, proneness to boredom, and novelty seeking. Recently, research suggests that youth with CU traits, similarly to adults with psychopathy, can present a low-anxious ?primary? and high-anxious ?secondary? variants. Our aim is to critically review the main measures of psychopathic traits, including the three main dimensions (with specific emphasis on CU traits), and the ?primary/secondary? distinction, focusing on the assessment in clinical settings. An assessment procedure is proposed, based on previous literature and personal clinical experience.
    Article · Sep 2016 · Neuroscience & Biobehavioral Reviews
  • [Show abstract] [Hide abstract] ABSTRACT: This article investigates the processing of vestibular information by interpreting current experimental knowledge in the framework of predictive coding. We demonstrate that this theoretical framework give us insights into several important questions regarding specific properties of the vestibular system. Particularly, we discuss why the vestibular network is more spatially distributed than other sensory networks, why a mismatch in the vestibular system is more clinically disturbing than in other sensory systems, why the vestibular system is only marginally affected by most cerebral lesions, and whether there is a primary vestibular cortex. The use of predictive coding as a theoretical framework further points to some problems with the current interpretation of results that are gained from vestibular stimulation studies. In particular, we argue that cortical responses of vestibular stimuli cannot be interpreted in the same way as responses of other sensory modalities. Finally, we discuss the implications of the new insights, hypotheses and problems that were identified in this review on further directions of research of vestibular information processing.
    Article · Sep 2016 · Neuroscience & Biobehavioral Reviews
  • Article · Sep 2016 · Neuroscience & Biobehavioral Reviews
  • [Show abstract] [Hide abstract] ABSTRACT: Down syndrome (DS; trisomy 21), the commonest genetic cause of mental disability, affects approximately 250,000 families in the United States alone. Despite milestones in understanding the specific genetic causes of the syndrome, the major symptoms of DS − not least those related to neurocognitive function − are incurable. DS phenotypes are highly variable, and gene expression patterns cannot be explained by trisomy alone, implicating epigenetics in DS pathophysiology. DNA and histone modifications appear to contribute to DS pathology and cognitive defects, and epigenomic, and genome editing research have very recently opened up novel therapeutic avenues for several diseases including DS. Here we discuss how epigenomic therapies might be used to ameliorate DS-related phenotypes with a particular focus on the CRISPR-Cas 9 system for targeted epigenomic engineering in DS. This approach is likely to reap rewards in terms of understanding the pathophysiology of DS, especially when combined with animal models, but significant technical and ethical challenges must be overcome for clinical translation.
    Article · Sep 2016 · Neuroscience & Biobehavioral Reviews
  • [Show abstract] [Hide abstract] ABSTRACT: Public opinion surrounding the recreational use and therapeutic potential of cannabis is shifting. This review describes new work examining the behavioural and neural effects of cannabis and the endocannabinoid system, highlighting key regions within corticolimbic brain circuits. First, we consider the role of human genetic factors and cannabis strain chemotypic differences in contributing to interindividual variation in the response to cannabinoids, such as THC, and review studies demonstrating that THC-induced impairments in decision-making processes are mediated by actions at prefrontal CB1 receptors. We further describe evidence that signalling through prefrontal or ventral hippocampal CB1 receptors modulates mesolimbic dopamine activity, aberrations of which may contribute to emotional processing deficits in schizophrenia. Lastly, we review studies suggesting that endocannabinoid tone in the amygdala is a critical regulator of anxiety, and report new data showing that FAAH activity is integral to this response. Together, these findings underscore the importance of cannabinoid signalling in the regulation of cognitive and affective behaviours, and encourage further research given their social, political, and therapeutic implications.
    Article · Sep 2016 · Neuroscience & Biobehavioral Reviews
  • [Show abstract] [Hide abstract] ABSTRACT: Huntington’s disease (HD) is a fatal neurodegenerative disease caused by an extended polyglutamine tract in the huntingtin protein. Circadian, sleep and hypothalamic-pituitary-adrenal (HPA) axis disturbances are observed in HD as early as 15 years before clinical disease onset. Disturbances in these key processes result in increased cortisol and altered melatonin release which may negatively impact on brain-derived neurotrophic factor (BDNF) expression and contribute to documented neuropathological and clinical disease features. This review describes the normal interactions between neurotrophic factors, the HPA-axis and circadian rhythm, as indicated by levels of BDNF, cortisol and melatonin, and the alterations in these intricately balanced networks in HD. We also discuss the implications of these alterations on the neurobiology of HD and the potential to result in hypothalamic, circadian, and sleep pathologies. Measurable alterations in these pathways provide targets that, if treated early, may reduce degeneration of brain structures. We therefore focus here on the means by which multidisciplinary therapy could be utilised as a non-pharmaceutical approach to restore the balance of these pathways.
    Article · Sep 2016 · Neuroscience & Biobehavioral Reviews
  • [Show abstract] [Hide abstract] ABSTRACT: Detecting and evaluating emotional information from facial expressions as a basis for behavioural adaption belong to the core social-cognitive abilities of mankind. Dysfunctions in emotional face processing are observed in several major psychiatric disorders like depression and schizophrenia. In search for psychiatric disease biomarkers using the imaging genetics approach, serotonergic gene polymorphisms have been associated with altered brain circuit activation during emotional face processing. Especially the 5-HTTLPR gene polymorphism has been extensively investigated in association with emotion regulation processes. In this article, imaging genetics literature on emotional face processing, reporting genetic effects of 5-HTTLPR in healthy volunteers is reviewed. Additionally, these results are regarded in relation to pharmacologic challenge (antidepressants, acute tryptophan depletion) imaging studies and discussed in light of recent neurobiological evidence with a focus on serotonin (5-HT1A, 5-HT2C, 5-HT2A) receptor findings.
    Article · Sep 2016 · Neuroscience & Biobehavioral Reviews
  • [Show abstract] [Hide abstract] ABSTRACT: The "affective" and "cognitive" neuroscience approaches to understanding emotion (AN and CN, respectively) represent potentially synergistic, but as yet unreconciled, theoretical perspectives, which may in part stem from the methods that these distinct perspectives routinely employ - one focusing on animal brain emotional systems (AN) and one on diverse human experimental approaches (CN). Here we present an exchange in which each approach (1) describes its own theoretical perspective, (2) offers a critique of the other perspective, and then (3) responds to each other's critique. We end with a summary of points of agreement and disagreement, and describe possible future experiments that could help resolve the remaining controversies. Future work should (i) further characterize the structure/function of subcortical circuitry with respect to its role in generating emotion, and (ii) further investigate whether sub-neocortical activations alone are sufficient (as opposed to merely necessary) for affective experiences, or whether subsequent cortical representation of an emotional response is also required.
    Article · Sep 2016 · Neuroscience & Biobehavioral Reviews