Human vaccines (HUM VACCINES)

Publisher: Taylor & Francis

Journal description

Human Vaccines is a unique new peer-reviewed journal with an international audience that covers the following topics: discovery, research, enabling technologies, preclinical development, toxicology, product development, assays and quality control, process development, clinical studies, regulatory affairs, commercial, utilization, policy, safety, epidemiology, preventive vaccines, therapeutic vaccines, infectious disease targets, and non-infectious disease targets, e.g., cancer, allergy, autoimmunity.

Current impact factor: 3.64

Impact Factor Rankings

2016 Impact Factor Available summer 2017
2013 Impact Factor 3.643
2012 Impact Factor 3.136
2011 Impact Factor 3.577
2010 Impact Factor 2.042
2009 Impact Factor 1.94

Impact factor over time

Impact factor

Additional details

5-year impact 2.94
Cited half-life 2.70
Immediacy index 0.52
Eigenfactor 0.01
Article influence 0.87
Website Human Vaccines website
Other titles Human vaccines (Online), Human vaccines
ISSN 1554-8619
OCLC 57894614
Material type Document, Periodical, Internet resource
Document type Internet Resource, Computer File, Journal / Magazine / Newspaper

Publisher details

Taylor & Francis

  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author can archive a post-print version
  • Conditions
    • Some individual journals may have policies prohibiting pre-print archiving
    • On author's personal website or departmental website immediately
    • On institutional repository or subject-based repository after either 12 months embargo
    • Publisher's version/PDF cannot be used
    • On a non-profit server
    • Published source must be acknowledged
    • Must link to publisher version
    • Set statements to accompany deposits (see policy)
    • The publisher will deposit in on behalf of authors to a designated institutional repository including PubMed Central, where a deposit agreement exists with the repository
    • STM: Science, Technology and Medicine
    • Publisher last contacted on 25/03/2014
    • This policy is an exception to the default policies of 'Taylor & Francis'
  • Classification

Publications in this journal

  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: This special issue of Human Vaccines is based on the Seventh World Congress on Vaccines, Immunisation and Immunotherapy (WCVII), which was organized from 26 to 28 of May 2010 by the Infections Control World Organization (ICWO) in Berlin, Germany. The venue of the Congress at the elegant Kaiserin Friedrich Haus (previously harboring the Academy of Arts of East Germany) was located in the historic city center. The full three days of Congress with morning plenary sessions, afternoon symposia, and poster presentations were attended, from all continents, by medical specialists in immunisation, immunotherapy and scientists devoted to developing new immunogenic and safe vaccines. The Congress was held under the auspices and with the scientific cooperation of Medical Faculties of the University of Montreal, Charité-Universitätsmedizin Berlin, University of Genoa, University of Barcelona, University of Florence, University of Milan, Griffith University, Gold Coast, Robert-Koch-Institute, Berlin, Max-Planck-Institute for Infection Biology, Berlin, Karolinska Institutet, Stockholm, Fraunhofer USA Center for Molecular Biotechnology, and Netherlands Vaccine Institute, among others. The opening lecture of the Congress on new vaccination strategies against tuberculosis was delivered by Professor Dr Stefan H.E. Kaufmann, Director of the Max-Planck-Institute.
    Full-text · Article · Sep 2014 · Human vaccines
  • [Show abstract] [Hide abstract]
    ABSTRACT: Uterine cancer is the most common pelvic gynecological malignancy. Uterine sarcomas and relapsed uterine carcinomas have limited treatment options. The search for new therapies is urgent. Dendritic cell (DC) immunotherapy holds much promise, though has been poorly explored in uterine cancer. This commentary gives an insight in existing DC immunotherapy studies in uterine cancer and summarizes the possibilities and the importance of the loading of tumor antigens onto DC and their subsequent maturation. However, the sole application of DC immunotherapy to target uterine cancer will be insufficient because of tumor-induced immunosuppression, which will hamper the establishment of an effective anti-tumor immune response. The authors give an overview on the limited existing immunosuppressive data and propose a novel approach on DC immunotherapy in uterine cancer.
    No preview · Article · Apr 2014 · Human vaccines

  • No preview · Article · Mar 2012 · Human vaccines

  • No preview · Article · Jan 2012 · Human vaccines
  • [Show abstract] [Hide abstract]
    ABSTRACT: Generating protective immune responses in older adults (particularly ≥65 y) remains challenging for vaccines in general. This study examined the immune response engendered in older adults by RECOMBIVAX HB™ manufactured using a modified adjuvant (modified-process hepatitis B vaccine; mpHBV), RECOMBIVAX-HB™, and ENGERIX-B™. Randomized, double-blind, multicenter study enrolled healthy, seronegative subjects (N=538) to receive mpHBV (10 µg hepatitis B surface antigen [HBsAg]), RECOMBIVAX-HB™ (10 µg HBsAg), or ENGERIX-B™ (20 µg HBsAg) at Day 1, Month 1, and Month 6. Prespecified analysis of subpopulations 50-64 y and ≥65 y was conducted. Serum antibody to HBsAg (anti-HBs) was measured Predose 1 and 1 mo Postdose 3. For subjects ≥50 y, seroprotection rates (SPR, anti-HBs titer ≥10 mIU/mL) were 75.7% (95% CI: 68.0,82.2) for mpHBV, 68.0% (95% CI: 59.8,75.5) for RECOMBIVAX HB™, and 84.0% (95% CI: 77.0,89.6) for ENGERIX-B™. For subjects 50-64 y, SPRs were 82.1% (95% CI: 73.8,88.7) for mpHBV, 77.4% (95% CI: 68.7,84.7) for RECOMBIVAX-HB™, and 88.5% (95% CI: 81.1,93.7) for ENGERIX-B™. For subjects ≥65 y, SPRs were 57.5% (95% CI: 40.9,73.0) for mpHBV, 34.4% (95% CI: 18.6,53.2) for RECOMBIVAX-HB™, and 67.7% (95% CI: 48.6,83.3) for ENGERIX-B™. There were 6 non-vaccine related serious adverse events reported. The majority of subjects ≥50 y old achieved seroprotection. The sub-population ≥65 y had lower vaccination responses than the 50-64 y sub-population. For subjects ≥65 y, mpHBV and ENGERIX-B™ groups achieved higher seroprotection rates than the RECOMBIVAX-HB group. The safety profile of mpHBV was consistent with the other groups.
    No preview · Article · Dec 2011 · Human vaccines

  • No preview · Article · Dec 2011 · Human vaccines
  • [Show abstract] [Hide abstract]
    ABSTRACT: Dr. Yin started his research on infectious disease prevention in the 1980s. In 1985, Dr. Yin sucessfully isolated the hepatitis A virus, after which, in 2002, he developed the first proprietary inactivated hepatitis A vaccine in China and soon launched it into the China market. Led by Dr. Yin, Sinovac successfully developed the vaccine prducts against SARS, H5N1, H1N1, hepatitis A and B and infleunza. Currently, Sinovac is working on the R&D of EV71 vaccine against hand, foot and mouth disease, and pneumococcal conjugate vaccine. Sinovac aims to provide Chinese children with international quality vaccines, and provide children in the world with vaccines made in China.
    No preview · Article · Dec 2011 · Human vaccines
  • [Show abstract] [Hide abstract]
    ABSTRACT: In children treated with immunosuppressive medication such as methotrexate and tumor necrosis factor-alpha (TNF-α) inhibitors, additional immunizations are recommended because of increased susceptibility to infections. However, it is unclear if adequate antibody response to vaccinations can be established in children receiving methotrexate and/or TNF-α inhibitors. In a prospective open label study, we assessed seroprotection and seroconversion following influenza vaccination during 2 seasons (6 strains) in 36 children with autoimmune disease treated either with methotrexate (n=18), TNF-α inhibitors (n=10) or both (n=8) and a control group of 16 immunocompetent children. Influenza antibody titers were determined by hemagglutinin inhibition assay, before and 4-8 weeks after vaccination. Post-vaccination seroprotection (defined as a titer ≥1:40) did not significantly differ between immunosuppressed and immunocompetent subjects. Seroconversion, defined as the change from a nonprotective (< 1:40) to a protective titer (≥1:40) with at least a 4-fold titer increase, was less likely to occur in immunosuppressed patients, although no significant difference from the control group was established. Safety evaluation of vaccination showed no serious adverse events. Children receiving methotrexate and/or TNF-α inhibitors can be safely and effectively immunized against influenza, with a seroprotection after vaccination comparable to immunocompetent children.
    No preview · Article · Dec 2011 · Human vaccines