Trends in Molecular Medicine (TRENDS MOL MED)
Trends in Molecular Medicine's objective is to facilitate communication between groups of highly trained professionals with distinct backgrounds and skills, whose common goals are to understand and explain the molecular basis of disease with a view to new clinical practice. Trends in Molecular Medicine is a resource for students and professionals alike, who have information needs that transcend the traditional clinical or scientific categorisation. Trends in Molecular Medicine includes review articles on the genetic basis of disease, but 'molecular' does not only mean DNA. The diagnostic role of genetic processes is clear, but major benefits in health and disease are also provided by other molecules: enzymes, antibiotics, hormones, metals, carbohydrates, lipids, vitamins, synthetic organic and inorganic polymers. Such benefits are discussed and evaluated by Trends in Molecular Medicine. Furthermore 'Medicine' involves a vital societal element; molecular intervention raises controversial ethical, legal and financial issues. All these issues are addressed in Trends in Molecular Medicine in a style that builds on 25 years' experience of publishing the Trends Journals.
Journal Impact: 7.09*
Journal impact history
|2016 Journal impact||Available summer 2017|
|2015 Journal impact||7.09|
|2011 Journal impact||16.77|
|2010 Journal impact||13.69|
|2009 Journal impact||14.28|
|2008 Journal impact||12.46|
|2007 Journal impact||8.17|
|2006 Journal impact||6.41|
|2005 Journal impact||6.43|
|2004 Journal impact||6.44|
|2003 Journal impact||3.62|
|2002 Journal impact||1.83|
Journal impact over time
|Website||Trends in Molecular Medicine website|
|Other titles||Trends in molecular medicine (Online)|
|Material type||Document, Periodical, Internet resource|
|Document type||Internet Resource, Computer File, Journal / Magazine / Newspaper|
Publications in this journal
- [Show abstract] [Hide abstract] ABSTRACT: Crowdsourcing presents a novel approach to solving complex problems within molecular medicine. By leveraging the expertise of fellow scientists across the globe, broadcasting to and engaging the public for idea generation, harnessing a scalable workforce for quick data management, and fundraising for research endeavors, crowdsourcing creates novel opportunities for accelerating scientific progress. Copyright © 2015 Elsevier Ltd. All rights reserved.
- [Show abstract] [Hide abstract] ABSTRACT: INPP4B acts as a tumor suppressor in various epithelial cancers by inhibiting PI3K/Akt signaling. Unexpectedly, tumor-promoting features of INPP4B in leukemia and breast cancer have been recently uncovered. In this spotlight, we discuss the seemingly paradoxical nature of INPP4B-mediated signaling in cancer. Copyright © 2015 Elsevier Ltd. All rights reserved.
- [Show abstract] [Hide abstract] ABSTRACT: Placebos are indispensable controls in randomized clinical trials (RCTs), and placebo responses significantly contribute to routine clinical outcomes. Recent neurophysiological studies reveal neurotransmitter pathways that mediate placebo effects. Evidence that genetic variations in these pathways can modify placebo effects raises the possibility of using genetic screening to identify placebo responders and thereby increase RCT efficacy and improve therapeutic care. Furthermore, the possibility of interaction between placebo and drug molecular pathways warrants consideration in RCT design. The study of genomic effects on placebo response, 'the placebome', is in its infancy. Here, we review evidence from placebo studies and RCTs to identify putative genes in the placebome, examine evidence for placebo-drug interactions, and discuss implications for RCTs and clinical care. Copyright © 2015 Elsevier Ltd. All rights reserved.
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