Asian Journal of Pharmaceutical and Clinical Research

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ISSN 0974-2441

Publications in this journal

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    ABSTRACT: Health and wellness are key drivers of new product development, globally. Obesity and excess calories are issues on one extreme, and lack of nutrients is an issue at the other extreme. Consumers are also seeking out new kinds of indulgence, driving demand for new ethnic and exotic flavors, and authentic regional products. The health benefits of super-fruits have made them successful as ingredients for food companies and as a source of exciting new flavors for consumers. The super-fruits deemed super by nutrition scientists are packed with antioxidants, fiber, vitamins, minerals, and other nutrients that improve health condition. The importance of super-fruits as a necessary part of the human diet and as cash crops is wellrecognized. They help to prevent a number of extremely chronic human diseases. In recent years, this term - originally used by the food industry to indicate fruit having an exceptional nutrient richness and nutritional qualities, including a high concentration of phytochemicals - has been increasingly and generically utilized, mainly for marketing purposes. In India, traditional fruits, such as bael, aonla, pomegranate, guava, pineapple, coconut, grapefruit, litchi, jackfruit, papaya, grape, and so many indigenous minor fruits, are rich in above-mentioned phytochemicals and antioxidant compound that include them in the list of super-fruit. In this present paper, we critically review the extraordinary-therapeutic characteristics of superfruit, mainly to aware the common people and to speed-up the super-fruit cultivation. © 2016, Asian Journal of Pharmaceutical and Clinical Research. All rights reserved.
    No preview · Article · Jan 2016 · Asian Journal of Pharmaceutical and Clinical Research

  • No preview · Article · Jan 2016 · Asian Journal of Pharmaceutical and Clinical Research

  • No preview · Article · Nov 2015 · Asian Journal of Pharmaceutical and Clinical Research

  • No preview · Article · Oct 2015 · Asian Journal of Pharmaceutical and Clinical Research
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    ABSTRACT: Objectives: Allicin is an organosulfur compound featuring thiosulfinate functional group. The compound is formed in garlic after tissue damage, by the action of enzyme alliinase on alliin. This study involves extraction of allicin from garlic using high-performance liquid chromatography (HPLC) and study of it is the genotoxic effect on human leukocytes. Methods: A simple and rapid reverse phase HPLC was used for the extraction of allicin. Quality allicin, in conjugation with chymosin, was used to study its genotoxic effect on leukocytes. Results: Garlic oil and garlic extract showed similar retention time, and we measured the products using genotoxic effects in human leukocyte culture and it shows statistically not significant. Conclusion: This study suggested that to take a lower concentration of garlic extracts benefits for health and these findings useful for further research. © 2015, Asian Journal of Pharmaceutical and Clinical Research. All rights reserved.
    No preview · Article · Sep 2015 · Asian Journal of Pharmaceutical and Clinical Research
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    ABSTRACT: Over the past 30 years, as the expense and complications involved in marketing new drug entities have increased, with concomitant recognition of the therapeutic advantages of controlled drug delivery, greater attention has been focused on development of sustained or controlled release drug delivery systems (DDS). For many disease states, a substantial number of therapeutically effective compounds already exist. The effectiveness of these drugs is often limited by side effects or necessity to administer the compound in an ethical setting. The goal in designing sustained drug delivery is to reduce the frequency of dosing or to increase the effectiveness of the drug by localization at the site of action, reducing the dose required or providing uniform drug delivery. The design of oral sustained release DDS depends on various factors such as, physicochemical properties of drug, type of delivery system, disease being treated, and patient condition, and treatment duration, presence of food, gastrointestinal motility, and coadministration of other drugs.
    No preview · Article · Sep 2015 · Asian Journal of Pharmaceutical and Clinical Research
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    ABSTRACT: Objective: To demonstrate whether clove oil enhances the antibacterial effect of intracanal medicaments. Methods: Materials used include clove oil, Enterococcus faecalis microorganism, intracanal medicaments (metronidazole, ciprofloxacin, clindamycin, and calcium hydroxide), agar plates, motor, pestle, weighing machine, propylene glycol, glass slab, scale. Agar well diffusion method is employed to study the antibacterial effects of intra canal medicaments with and without clove oil against E. faecalis. Results: From the obtained results it can be concluded that intra canal medicaments combined with clove oil showed greater antibacterial effects against the microorganism, E. faecalis, than those intracanal medicaments without clove oil. Conclusion: The ultimate goals of intracanal medicaments are complete elimination of bacteria, their by-products and pulpal remnants from infected root canals and the complete seal of disinfected root canals. Clove oil can be attributed to its antimicrobial, antifungal, antiseptic, antiviral, aphrodisiac, and stimulating properties. Eugenol in clove essential oil has an inhibitory effect on various bacteria and should be used in minimum inhibitory concentration for safe and effective results. It is used to treat patients with pain from a dry socket, as well as used in a number of temporary restorative materials. Intracanal medicaments when combined with other substances may produce additive or synergistic effects. In this study, the synergistic effect of clove oil when mixed with other intracanal medicaments is tested and found to be more effective. © 2015, Asian Journal of Pharmaceutical and Clinical Research. All Rights Reserved.
    No preview · Article · Sep 2015 · Asian Journal of Pharmaceutical and Clinical Research