Magnetic Resonance in Medicine (MAGN RESON MED)

Publisher: Society of Magnetic Resonance in Medicine (U.S.); International Society for Magnetic Resonance in Medicine, Wiley

Journal description

Magnetic Resonance in Medicine is an international journal devoted to the publication of original investigations concerned with all aspects of the development and use of nuclear magnetic resonance and electron paramagnetic resonance techniques for medical applications.

Current impact factor: 3.57

Impact Factor Rankings

2016 Impact Factor Available summer 2017
2014 / 2015 Impact Factor 3.571
2013 Impact Factor 3.398
2012 Impact Factor 3.267
2011 Impact Factor 2.964
2010 Impact Factor 3.267
2009 Impact Factor 3.225
2008 Impact Factor 3.449
2007 Impact Factor 3.131
2006 Impact Factor 3.427
2005 Impact Factor 3.508
2004 Impact Factor 3.468
2003 Impact Factor 3.313
2002 Impact Factor 3.25
2001 Impact Factor 3.437
2000 Impact Factor 3.121
1999 Impact Factor 3.757
1998 Impact Factor 2.962
1997 Impact Factor 3.012

Impact factor over time

Impact factor

Additional details

5-year impact 3.75
Cited half-life 9.80
Immediacy index 0.76
Eigenfactor 0.04
Article influence 1.21
Website Magnetic Resonance in Medicine website
Other titles Magnetic resonance in medicine (Online), Magnetic resonance in medicine
ISSN 0740-3194
OCLC 44077775
Material type Document, Periodical, Internet resource
Document type Internet Resource, Computer File, Journal / Magazine / Newspaper

Publisher details


  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author cannot archive a post-print version
  • Restrictions
    • 12 months embargo for scientific, technical and medicine titles
    • 2 years embargo for humanities and social science titles
  • Conditions
    • Some journals have separate policies, please check with each journal directly
    • On author's personal website, institutional repositories, arXiv, AgEcon, PhilPapers, PubMed Central, RePEc or Social Science Research Network
    • Author's pre-print may not be updated with Publisher's Version/PDF
    • Author's pre-print must acknowledge acceptance for publication
    • On a non-profit server
    • Publisher's version/PDF cannot be used
    • Publisher source must be acknowledged with citation
    • Must link to publisher version with set statement (see policy)
    • If OnlineOpen is available, BBSRC, EPSRC, MRC, NERC and STFC authors, may self-archive after 12 months
    • If OnlineOpen is not available, BBSRC, EPSRC, MRC, NERC and STFC authors, may self-archive after 6 months
    • If OnlineOpen is available, AHRC and ESRC authors, may self-archive after 24 months
    • If OnlineOpen is not available, AHRC and ESRC authors, may self-archive after 12 months
    • Reviewed 18/03/14
    • Please see former John Wiley & Sons and Blackwell Publishing policies for articles published prior to February 2007
  • Classification

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: Purpose: Inhomogeneities of the main magnetic field cause line broadening and location-dependent frequency shifts in brain MRSI. These are often visible despite advanced B0 shimming. The purpose of this work is to propose an advanced B0 correction method that can easily be applied during postprocessing. Methods: A target-driven overdiscrete reconstruction method previously introduced for MRSI is modified by dividing it into two steps. In a first step, an intermediate spectroscopic image with arbitrarily high resolution is generated, on which B0 correction is performed as an additional processing step based on an additionally acquired B0 map. This frequency-aligns metabolite peaks and destroys noise correlations between neighboring subvoxels. Second, the voxel is shaped by application of the spatial response target. The method was tested with simulated spectroscopic imaging data as well as in a series of MRSI data sets obtained from four healthy volunteers at 7T. Results: A systematic gain in spectral signal-to-noise ratio is achieved, due to spatial averaging now occurring over peak aligned and noise decorrelated subvoxel spectra. At the same time, metabolite peak line widths are reduced. Conclusion: In the presence of B0 inhomogeneities across the field of view, the proposed method offers the potential to improve spectral quality with only a minimal additional effort during acquisition. Magn Reson Med, 2015. © 2015 Wiley Periodicals, Inc.
    No preview · Article · Feb 2016 · Magnetic Resonance in Medicine
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    ABSTRACT: Multifractal applications to resting state functional MRI (rs-fMRI) time series for diagnosing Alzheimer's disease (AD) are still limited. We aim to address two issues: (I) if and what multifractal features are sufficiently discriminative to detect AD from the healthy; (II) if AD classification could be further improved by combining multifractal features with traditional features in this field. Rs-fMRI data of 25 AD patients and 38 normal controls were analyzed. A set of multifractal features were systematically investigated. Traditional features in monofractal, linear, and network-based categories were also extracted for comparison and combination. Both support vector machines and multiple kernel learning (MKL) were used to perform classification with individual and combined features. We identified a multifractal feature, Δf, which has the strongest discriminative power among all the features in our study. Moreover, we found that the classification accuracy could be significantly improved from 69% (by Δf only) to up to 76%, when nonsparse MKL is used to combine Δf with the monofractal feature, Hurst. Finally, we showed that incorporating other multifractal features, α(0), Δα and Pc, could also improve traditional-feature-based AD classification. Our work demonstrated the potential usefulness of multifractal analysis for AD research, especially when combining with the traditional rs-fMRI features. It contributes to distinguishing AD from NC subjects. Magn Reson Med, 2015. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.
    No preview · Article · Jul 2015 · Magnetic Resonance in Medicine
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    ABSTRACT: Purpose: Compressed sensing methods with motion estimation and compensation techniques have been proposed for the reconstruction of accelerated dynamic MRI. However, artifacts that naturally arise in compressed sensing reconstruction procedures hinder the estimation of motion from reconstructed images, especially at high acceleration factors. This work introduces a robust groupwise nonrigid motion estimation technique applied to the compressed sensing reconstruction of dynamic cardiac cine MRI sequences. Theory and Methods: A spatio-temporal regularized, groupwise, nonrigid registration method based on a B-splines deformation model and a least squares metric is used to estimate and to compensate the movement of the heart in breath-hold cine acquisitions and to obtain a quasistatic sequence with highly sparse representation in temporally transformed domains. Results: Short axis in vivo datasets are used for validation, both original multicoil as well as DICOM data. Fully sampled data were retrospectively undersampled with various acceleration factors and reconstructions were compared with the two well-known methods k-t FOCUSS and MASTeR. The proposed method achieves higher signal to error ratio and structure similarity index for medium to high acceleration factors. Conclusions: Reconstruction methods based on groupwise registration show higher quality reconstructions for cardiac cine images than the pairwise counterparts tested.
    No preview · Article · May 2015 · Magnetic Resonance in Medicine
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    ABSTRACT: PurposeOne of the main safety concerns in MR is heating of the subject due to radiofrequency (RF) exposure. Recently was shown that local peak temperatures can reach dangerous values and the most prominent parameter for accurate temperature estimations is thermoregulation. Therefore, the goal of this research is testing the feasibility of measuring thermoregulation in vivo using MR methods.Theory and Methods The calves of 13 volunteers were scanned at 3 tesla. A Proton Resonance Frequency Shift method was used for temperature measurement. Arterial Spin Labeling and phase contrast scans were used for perfusion and flow measurements respectively. The calves were monitored during extreme RF exposure (20 W/kg, 16 min) and after physical exercise.ResultsTemperature increases due to RF absorption (range of the 90th percentile of all volunteers: 1.1-2.5°C) matched with the reference skin temperature changes. Increases in perfusion and flow were defined on the whole leg and normalized to baseline. Perfusion showed a significant increase due to RF heating (ratio compared with baseline: 1.28 ± 0.37; P < 0.05), the influence of exercise was much greater, however (2.97 ± 2.45, P < 0.01).Conclusion This study represents a first exploration of measuring thermoregulation, which will become essential when new safety guidelines are based on thermal dose. Magn Reson Med, 2015. © 2015 Wiley Periodicals, Inc.
    No preview · Article · May 2015 · Magnetic Resonance in Medicine
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    ABSTRACT: PurposeDipole antennas in ultrahigh field MRI have demonstrated advantages over more conventional designs. In this study, the fractionated dipole antenna is presented: a dipole where the legs are split into segments that are interconnected by capacitors or inductors.MethodsA parameter study has been performed on dipole antenna length using numerical simulations. A subsequent simulation study investigates the optimal intersegment capacitor/inductor value. The resulting optimal design has been constructed and compared to a previous design, the single-side adapted dipole (SSAD) by simulations and measurements. An array of eight elements has been constructed for prostate imaging on four subjects (body mass index 20-27.5) using 8 × 2 kW amplifiers.ResultsFor prostate imaging at 7T, lowest peak local specific-absorption rate (SAR) levels are achieved if the antenna is 30 cm or longer. A fractionated dipole antenna design with inductors between segments has been chosen to achieve even lower SAR levels and more homogeneous receive sensitivities.Conclusion With the new design, good quality prostate images are acquired. SAR levels are reduced by 41% to 63% in comparison to the SSAD. Coupling levels are moderate (average nearest neighbor: −14.6 dB) for each subject and prostate levels range from 12 to 18 μT. Magn Reson Med, 2015. © 2015 Wiley Periodicals, Inc.
    No preview · Article · Apr 2015 · Magnetic Resonance in Medicine
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    ABSTRACT: Hyperpolarization of carbon-13 ((13) C) nuclei by dissolution dynamic nuclear polarization increases signal-to-noise ratio (SNR) by >10,000-fold for metabolic imaging, but care must be taken when transferring hyperpolarized (HP) samples from polarizer to MR scanner. Some (13) C substrates relax rapidly in low ambient magnetic fields. A handheld electromagnet carrier was designed and constructed to preserve polarization by maintaining a sufficient field during sample transfer. The device was constructed with a solenoidal electromagnet, powered by a nonmagnetic battery, holding the HP sample during transfer. A specially designed switch automated deactivation of the field once transfer was complete. Phantom and rat experiments were performed to compare MR signal enhancement with or without the device for HP [(13) C]urea and [1-(13) C]pyruvate. The magnetic field generated by this device was tested to be >50 G over a 6-cm central section. In phantom and rat experiments, [(13) C]urea transported via the device showed SNR improvement by a factor of 1.8-1.9 over samples transferred through the background field. A device was designed and built to provide a suitably high yet safe magnetic field to preserve hyperpolarization during sample transfer. Comparative testing demonstrated SNR improvements of approximately two-fold for [(13) C]urea while maintaining SNR for [1-(13) C]pyruvate. Magn Reson Med, 2015. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.
    No preview · Article · Mar 2015 · Magnetic Resonance in Medicine
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    ABSTRACT: MR safety at 7 Tesla relies on accurate numerical simulations of transmit electromagnetic fields to fully assess local specific absorption rate (SAR) safety. Numerical simulations for SAR safety are currently performed using models of healthy patients. These simulations might not be useful for estimating SAR in patients who have large lesions with potentially abnormal dielectric properties, e.g., brain tumors. In this study, brain tumor patient models are constructed based on scans of four patients with high grade brain tumors. Dielectric properties for the modeled tumors are assigned based on electrical properties tomography data for the same patients. Simulations were performed to determine SAR. Local SAR increases in the tumors by as much as 30%. However, the location of the maximum 10-gram averaged SAR typically occurs outside of the tumor, and thus does not increase. In the worst case, if the tumor model is moved to the location of maximum electric field intensity, then we do observe an increase in the estimated peak 10-gram SAR directly related to the tumor. Peak local SAR estimation made on the results of a healthy patient model simulation may underestimate the true peak local SAR in a brain tumor patient. Magn Reson Med, 2015. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.
    No preview · Article · Mar 2015 · Magnetic Resonance in Medicine
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    ABSTRACT: Purpose: A steady pulsed imaging and labeling (SPIL) scheme is proposed to obtain high-resolution multislice perfusion images of mice brain using standard preclinical MRI equipment. Theory and Methods: The SPIL scheme repeats a pulsed arterial spin labeling (PASL) module together with a short mixing time to extend the temporal duration of the generated PASL bolus to the total experimental time. Multislice image acquisition takes place during the mixing times. The mixing time is also used for magnetization recovery following image acquisition. The new scheme is able to yield multislice perfusion images rapidly. The perfusion kinetic curve can be measured by a multipulsed imaging and labeling (MPIL) scheme, i.e., acquiring single-slice ASL signals before reaching steady-state in the SPIL sequence. Results: When applying the SPIL method to normal mice, and to mice with unilateral ischemia, high-resolution multislice (five slices) CBF images could be obtained in 8 min. Perfusion data from ischemic mice showed clear CBF reductions in ischemic regions. The SPIL method was also applied to postmortem mice, showing that the method is free from magnetization transfer confounds. Conclusion: The new SPIL scheme provides for robust measurement of CBF with multislice imaging capability in small animals. Magn Reson Med, 2015. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.
    No preview · Article · Mar 2015 · Magnetic Resonance in Medicine
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    ABSTRACT: Purpose: Quantitative T2 -relaxation-based contrast has the potential to provide valuable clinical information. Practical T2 -mapping, however, is impaired either by prohibitively long acquisition times or by contamination of fast multiecho protocols by stimulated and indirect echoes. This work presents a novel postprocessing approach aiming to overcome the common penalties associated with multiecho protocols, and enabling rapid and accurate mapping of T2 relaxation values. Methods: Bloch simulations are used to estimate the actual echo-modulation curve (EMC) in a multi-spin-echo experiment. Simulations are repeated for a range of T2 values and transmit field scales, yielding a database of simulated EMCs, which is then used to identify the T2 value whose EMC most closely matches the experimentally measured data at each voxel. Results: T2 maps of both phantom and in vivo scans were successfully reconstructed, closely matching maps produced from single spin-echo data. Results were consistent over the physiological range of T2 values and across different experimental settings. Conclusion: The proposed technique allows accurate T2 mapping in clinically feasible scan times, free of user- and scanner-dependent variations, while providing a comprehensive framework that can be extended to model other parameters (e.g., T1 , B1 (+) , B0 , diffusion) and support arbitrary acquisition schemes.
    No preview · Article · Feb 2015 · Magnetic Resonance in Medicine
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    ABSTRACT: PurposeTo study how sensitivity encoding (SENSE) impacts periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) image quality, including signal-to-noise ratio (SNR), robustness to motion, precision of motion estimation, and image quality.Methods Five volunteers were imaged by three sets of scans. A rapid method for generating the g-factor map was proposed and validated via Monte Carlo simulations. Sensitivity maps were extrapolated to increase the area over which SENSE can be performed and therefore enhance the robustness to head motion. The precision of motion estimation of PROPELLER blades that are unfolded with these sensitivity maps was investigated. An interleaved R-factor PROPELLER sequence was used to acquire data with similar amounts of motion with and without SENSE acceleration. Two neuroradiologists independently and blindly compared 214 image pairs.ResultsThe proposed method of g-factor calculation was similar to that provided by the Monte Carlo methods. Extrapolation and rotation of the sensitivity maps allowed for continued robustness of SENSE unfolding in the presence of motion. SENSE-widened blades improved the precision of rotation and translation estimation. PROPELLER images with a SENSE factor of 3 outperformed the traditional PROPELLER images when reconstructing the same number of blades.ConclusionSENSE not only accelerates PROPELLER but can also improve robustness and precision of head motion correction, which improves overall image quality even when SNR is lost due to acceleration. The reduction of SNR, as a penalty of acceleration, is characterized by the proposed g-factor method. Magn Reson Med, 2014. © 2014 Wiley Periodicals, Inc.
    No preview · Article · Dec 2014 · Magnetic Resonance in Medicine
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    ABSTRACT: 1 PurposeRecent MRI studies have suggested that the magnetic susceptibility of white matter (WM) in the human brain is anisotropic, providing a new contrast mechanism for the visualization of fiber bundles and allowing the extraction of cellular compartment-specific information. This study provides an independent confirmation and quantification of this anisotropy.2 Methods Anisotropic magnetic susceptibility results in a torque exerted on WM when placed in a uniform magnetic field, tending to align the WM fibers with the field. To quantify the effect, excised spinal cord samples were placed in a torque balance inside the magnet of a 7 T MRI system and the magnetic torque was measured as function of orientation.3 ResultsAll tissue samples (n = 5) showed orienting effects, confirming the presence of anisotropic susceptibility. Analysis of the magnetic torque resulted in reproducible values for the WM volume anisotropy that ranged from 13.6 to 19.2 ppb.4 Conclusion The independently determined anisotropy values confirm estimates inferred from MRI experiments and validate the use of anisotropy to extract novel information about brain fiber structure and myelination. Magn Reson Med, 2014. © 2014 Wiley Periodicals, Inc.
    No preview · Article · Nov 2014 · Magnetic Resonance in Medicine
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    ABSTRACT: PurposeTo test the hypothesis that both coronary anatomy and ventricular function can be assessed simultaneously using a single four-dimensional (4D) acquisition. MethodsA free-running 4D whole-heart self-navigated acquisition incorporating a golden angle radial trajectory was implemented and tested in vivo in nine healthy adult human subjects. Coronary magnetic resonance angiography (MRA) datasets with retrospective selection of acquisition window width and position were extracted and quantitatively compared with baseline self-navigated electrocardiography (ECG) -triggered coronary MRA. From the 4D datasets, the left-ventricular end-systolic, end-diastolic volumes (ESV & EDV) and ejection fraction (EF) were computed and compared with values obtained from conventional 2D cine images. ResultsThe 4D datasets enabled dynamic assessment of the whole heart with isotropic spatial resolution of 1.15 mm(3). Coronary artery image quality was very similar to that of the ECG-triggered baseline scan despite some SNR penalty. A good agreement between 4D and 2D cine imaging was found for EDV, ESV, and EF. Conclusion The hypothesis that both coronary anatomy and ventricular function can be assessed simultaneously in vivo has been tested positive. Retrospective and flexible acquisition window selection allows to best visualize each coronary segment at its individual time point of quiescence. Magn Reson Med 74:1306-1316, 2015. (c) 2014 Wiley Periodicals, Inc.
    No preview · Article · Nov 2014 · Magnetic Resonance in Medicine