Clinical and experimental obstetrics & gynecology (CLIN EXP OBSTET GYN)

Publisher: Università di Padova. Clinica ostetrica ginecologica

Current impact factor: 0.42

Impact Factor Rankings

2016 Impact Factor Available summer 2017
2014 / 2015 Impact Factor 0.424
2013 Impact Factor 0.357
2012 Impact Factor 0.379
2011 Impact Factor 0.429
2010 Impact Factor 0.433
2009 Impact Factor 0.45

Impact factor over time

Impact factor
Year

Additional details

5-year impact 0.57
Cited half-life 6.10
Immediacy index 0.07
Eigenfactor 0.00
Article influence 0.13
Website Clinical & Experimental Obstetrics & Gynecology website
Other titles Clinical and experimental obstetrics & gynecology, Clinical and experimental obstetrics and gynecology
ISSN 0390-6663
OCLC 3995609
Material type Periodical
Document type Journal / Magazine / Newspaper

Publications in this journal


  • No preview · Article · Dec 2015 · Clinical and experimental obstetrics & gynecology
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    ABSTRACT: PURPOSE OF INVESTIGATION: To evaluate the effect of soy isoflavones and inulin (SII) on hot flushes (HF) and quality of life in a clinical setting, the authors conducted an observational study. MATERIALS AND METHODS: The authors performed an observational, prospective, multicentric study on women in peri-/post-menopause treated or untreated with a product present on the Italian market, consisting in a mixture of calcium (500 mg), vitamin D3 (300 IU), inulin (3 g) and soy isoflavones (40 mg). RESULTS: A total of 135 patients, 75 (55.6%) in the SII group and 60 (44.4%) in the untreated group entered the study. After three months, the mean number of HF declined of 2.8 (SD 3.7) in the SII group and 0.0 in the untreated one. The corresponding values after six months were -3.7 (SD 2.7) in the SII group and -0.9 (SD 5.3) in the control group (p = 0.02). CONCLUSION: This observational trial suggests a possible beneficial effect of a dietary soy supplement containing 40 mg of isoflavone/day plus inulin in the management of menopausal symptoms such as hot flashes.
    No preview · Article · Dec 2015 · Clinical and experimental obstetrics & gynecology
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    ABSTRACT: Endometriosis is characterized by the presence of histologically normal endometrial glands and stroma outside the uterine cavity. Endometriosis predominantly locates on peritoneal surfaces, but it also affects the vagina, vulva, and perineum, usually secondary to surgical or obstetric trauma. Endometriosis in an episiotomy scar is a fairly rare phenomenon. The authors present a case of endometriosis in an episiotomy scar.
    No preview · Article · Sep 2015 · Clinical and experimental obstetrics & gynecology
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    ABSTRACT: Aims: The objective of this study was to compare the frequencies of the presence of an embryonic pole and cardiac activity in miscarriages with normal and abnormal embryonic karyotypes. Materials and methods: From January 2008 to December 2012, 405 patients with early miscarriage were evaluated during pregnancy by regular ultrasound, and karyotyping was performed on chorionic villus tissue after curettage. The frequencies of the presence of an embryonic pole and cardiac activity were compared between patients with a normal embryonic karyotype and patients with an abnormal embryonic karyotype. Results: Of the 405 samples, 224 cases (55.3%) had an abnormal karyotype, and 181 cases (44.7%) had a normal karyotype. The frequencies of the presence of an embryonic pole and cardiac activity in miscarriages with normal embryonic chromosomes (71.8% and 57.5%, respectively) were similar to those of miscarriages with abnormal embryonic chromosomes (74.1% and 62.1%, respectively). The frequencies of the presence of an embryonic pole and cardiac activity were higher in miscarriages with viable autosomal trisomies (trisomies 21, 13, and 18), monosomy X, and triploidy than in miscarriages with a normal karyotype or other abnormal karyotypes. Conclusions: The frequencies of the presence of an embryonic pole and cardiac activity are higher in miscarriages with viable autosomal trisomies, monosomy X, and triploidy than in miscarriages with a normal karyotype or other abnormal karyotypes.
    No preview · Article · Sep 2015 · Clinical and experimental obstetrics & gynecology
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    ABSTRACT: Background: Monochorionic diamniotic (MCDA) twin pregnancy with gastroschisis cames a poor prognosis. Live birth and well development of both twins are extremely rare. Case: The authors report a rare case of discordant gastroschisis in MCDA twin. Both twins were followed up nine months after intrapartum fetal operation, and both are in good health until now. Conclusion: This report expands successful management of discordant gastroschisis in MCDA twins. Early diagnosis, intensive prenatal care, and multidisciplinary consultation are recommended in management of discordant gastroschisis in MCDA twin.
    No preview · Article · Sep 2015 · Clinical and experimental obstetrics & gynecology
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    ABSTRACT: Purpose: To evaluate the impact of new legislation for assisted reproductive technology (ART) restricting the number of transferred embryos on neonatal prognosis of infants born after infertility treatments. Materials and methods: Neonatal records of all live born infants in Ege University Maternity Ward were reviewed for 2006 and 2012. Neonatal outcome measures such as birth weight (BW), gestational age (GA), preterm birth (PTB), very low birth weight (VLBW), and neonatal intensive care unit (NICU) admission were evaluated. Results: Compared to 2006 percentage of newborns conceived by medically assisted reproduction (MAR) decreased from 14.6% to 5% in all live births, from 23.8% to 8.2% in NICU patients in 2012. The number of fetuses in the last pregnancy, frequency of intrauterine reductions, spontaneous pregnancy losses, antenatal bleeding, and premature delivery decreased. Percentage of multiples among MAR newborns (31.7% vs. 55.7%), twins from 51.4% to 30.9%, triplets from 4.3% to 0.8% all decreased significantly. Mean BW and gestational age increased resulting in decreased frequency of PTB and VLBW. Consequently Level 3 NICU admission rate significantly decreased from 44.3% to 22%. Conclusion: The new ART legislation in Turkey resulted in decreased rate of multiple births, prematurity and related complications, and NICU admissions in MAR newborns. However the twin rates are still high. Since uncontrolled ovulation stimulation and intrauterine insemination techniques are also associated with multiple births and unfavorable neonatal outcomes, these procedures deserve close monitorization.
    No preview · Article · Sep 2015 · Clinical and experimental obstetrics & gynecology
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    ABSTRACT: Objective: To compare the effects of ultrasonography with laparoscopy on transcervical resection of septa (TCRS). Materials and methods: The study included 126 patients with uterine septum at the present hospital between January 2010 and August 2012 that were randomly divided into two groups. Seventy patients had TCRS monitored by ultrasound (ultrasound group) while 56 patients were monitored by laparoscope (laparoscope group). Both groups were followed up for six to 24 months. The intraoperative status, short-term and long-term complications after operation, and pregnancy outcome of two groups were compared. Results: The operations of both groups were successfully completed. The operating time, the first time to get out of bed, postoperative 24hNRS (numeric rating scale) values, postoperative hospital stay, and the incidence of postoperative septum residue of ultrasound group were significantly less than laparoscope group (p < 0.05). No statistical differences were observed in intraoperative complications and pregnancy ratio between the two groups. Conclusion: Both ultrasound and laparoscope monitored TCRS were safe and effective in the treatment of uterine septum. Ultrasound monitored TCRS was more simple, economical, accurate, and non-invasive. For patients without abnormal lesions in pelvic cavity, the present authors tend to choose the ultrasound monitored TCRS.
    No preview · Article · Sep 2015 · Clinical and experimental obstetrics & gynecology
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    ABSTRACT: Purpose: To present a diagnostic and treatment paradigm for infertility designed for the obstetrician gynecologist generalist. Materials and methods: Simple methods of tubal evaluation, e.g., the hysterosalpingogram (HSG) and post-coital test to evaluate both male and cervical factor are discussed. Treating paradigms will be discussed for ovulatory disorders and luteal phase defects. The role of the OB/GYN generalist on performing surgery in the modem era will be mentioned. Results: If an HSG shows a unilateral hydrosalpinx the generalist should consider performing the unilateral salpingectomy since the advent of in vitro fertilization-embryo transfer (IVF-ET) with a de-emphasis on surgery has made the reproductive endocrinologist/infertility specialist (REI) less skillful in laparoscopic surgery. The REI rarely performs tuboplasty today. Not only does the exclusive treatment in the luteal phase with progesterone save the women money and side effects (including multiple births), but may actually improve pregnancy rates compared to the usual technique of follicle stimulating drugs plus intrauterine insemination. Conclusions: Because the generalist will not be tempted to suggest therapies, e.g., IVF-ET because this effective therapy is the best option for the financial success of the REI, but at the expense of financial depletion of the patient, there is plenty of room for generalists taking over as the first line physicians for infertility rather than just a referral service. Reproductive endocrinologists/infertility will almost invariably perform IUI each month even if not doing IVF which is also profitable to the REI, but costly in time and money to the patient. In contrast, the generalist, aimed with the knowledge that IUI does not improve pregnancy rates if the post-coital test is normal, will save the patient and/or the insurance money if the woman conceives. Obviously certain circumstances, e.g., bilateral blocked fallopian tubes or very severe oligoasthenozoospermia (but not teratozoospermia) will prompt an immediate referral to an REI.
    No preview · Article · Sep 2015 · Clinical and experimental obstetrics & gynecology
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    ABSTRACT: Struma ovarii represents an ovarian mature teratoma with thyroid tissue comprising more than 50% of the ovarian tumor. It is a rare condition, representing approximately 1% of all ovarian tumors with a potential malignant transformation 5% to 10%. When it is combined with pregnancy, it renders its management in this circumstance is extreme challenging. The authors present a case of benign struma ovarii diagnosed as a right adnexal mass during first trimester of pregnancy with an uneventful clinical course.
    No preview · Article · Sep 2015 · Clinical and experimental obstetrics & gynecology
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    ABSTRACT: Purpose of investigation: To investigate the roles of adipokines, free fatty acid (FFA), and oxidative stress in obese and non-obese preeclamptic patients. Materials and methods: Gestational age-matched obese preeclamptic (n=32), non-obese preeclamptic (n=32), and non-obese normotensive healthy (n=32) pregnant women were included in the study. Serum insulin, insulin resistance, leptin, nesfatin, ghrelin, chemerin, FFA levels, total antioxidant status, total oxidant status, and oxidative stress index were determined. Results: Leptin and nesfatin levels were significantly lower and ghrelin levels were significantly higher in the normotensive group as compared to the preeclamptic groups, while no difference was observed between obese and non-obese preeclamptic groups. Chemerin and FFA levels were significantly higher in obese preeclamptics as compared to non-obese preeclamptics and normotensive group. Total antioxidant status (TAS) levels were significantly higher in the normotensive group as compared to the preeclamptic groups, while no difference was observed between obese and non-obese preeclamptics. Total oxidative status (TOS) and oxidative stress index (OSI) levels were significantly lower in the normotensive group as compared to the preeclamptic groups, while no difference was observed between obese and non-obese preeclamptics. Conclusion: Serum levels of adipokines, TOS, and FFAs were significantly higher in pregnants with preeclampsia as compared to non-obese normotensive controls. Chemerin and FFA levels were significantly higher in obese preeclamptics as compared to non-obese preeclamptics.
    No preview · Article · Sep 2015 · Clinical and experimental obstetrics & gynecology
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    ABSTRACT: Objectives: The aim of the present study was to evaluate the eticacy of microwave endometrial ablation after endometrial curettage, in selected patients with heavy menstrual bleeding. Material and methods: Thirty-two premenopausal women with heavy menstrual bleeding underwent microwave endometrial ablation at the Department of Obstetrics and Gynecology of the University of Patras Medical School. All patients did not respond to previous medical treatment, had completed their childbearing, and did not desire future fertility. The authors chose endometrial curettage rather than hormonal pretreatment (GnRH analogs, danazol) for endometrial preparation. Posttreatment follow up protocol included physical and ultrasonographic evaluation at three, six, nine, and 12 months for the first year and yearly after. Results: The authors had no cases of uterine perforation, thermal injury to adjacent organs, and infection or sepsis. During follow up, there was a gradual decrease in amenorrhea rate (90.6% - 68.8%) and in satisfaction rate (90.6% - 71.9%). Moreover during follow up, eight women underwent to total abdominal hysterectomy. Among them, seven women had uterine myomas and one woman had adenomyosis. Conclusions: Endometrial preparation with endometrial curettage seems to be a good alternative to hormonal pretreatment. It has the advantage of avoiding delays, side effects, and cost of hormonal pretreatment. Moreover, microwave endometrial ablation after endometrial curettage is successful and highly acceptable.
    No preview · Article · Sep 2015 · Clinical and experimental obstetrics & gynecology
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    ABSTRACT: Purpose: To describe a distinctive pharmacological treatment for chronic pelvic pain and sciatica after spinal surgery with a laminectomy and spinal fusion failed to provide relief. Materials and methods: Dextroamphetamine suflate was prescribed to a woman with a history of chronic back pain which was attributed to a ruptured disc. The pain was still unbearable after surgery. Results: After adjusting dosage, within three months of the correct dose, 25 mg twice a day, relief was provided and has persisted for ten months. Conclusions: Chronic pelvic pain and sciatica both may be symptoms of hypofunction of the sympathetic nervous system. In addition, with other pain symptoms, this can be effectively treated with sympathomimetic amines.
    No preview · Article · Sep 2015 · Clinical and experimental obstetrics & gynecology
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    ABSTRACT: Idiopathic intracranial hypertension (IIH) is a rare neurologic disorder. It is also known as pseudotumor cerebri. The incidence of HH is one to two per 100,000 population annually. The higher incidence is in obese women from 15 to 44 years. The main symptoms are headache and visual loss. It mostly affects women of childbearing age who are overweight or obese. There are many theories of pathogenesis of HH, but precise pathogenesis is unknown. One of the causes of IIH is intracranial venous sinus thrombosis. It can cause increased cerebrospinal fluid (CSF) pressure by obstruction of venous outflow and blocking of CSF absorption. In polycystic ovary syndrome (PCOS) patients, thrombogenic tendency is increased due to increased aromatization of testosterone to estradiol which could induce estrogen-mediated thrombophilia. The authors present a 14-year-old girl with PCOS stigma who presented with a severe headache and papilledema. These symptoms were not improved by standard medical therapy of HH and PCOS, but improved after laparoscopic ovarian drilling. The authors report it with a review of the literature.
    No preview · Article · Sep 2015 · Clinical and experimental obstetrics & gynecology
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    ABSTRACT: Purpose: To evaluate and compare the morbidity and mortality of neonates born to pregnant women with positive and negative cervical cultures. Materials and methods: The demographic and clinical features of mothers included in this study, along with details of the microorganisms isolated on maternal cervical cultures and the number of days between a positive cervical culture and delivery were recorded. Neonates were stratified into two groups based on cervical culture results of their mothers--Group 1, positive cervical culture; Group 2, negative cervical culture. Results: A total of 216 women who delivered 242 infants were included in the study. Group 1 consisted of 90 neonates while Group 2 had 152 newborns. The difference between the groups with demographic characteristics was statistically insignificant. Mean levels of the acute phase reactants, CRP, and IL-6, obtained six hours after delivery were significantly higher in Group 1 compared to Group 2 (p < 0.05 for C-reactive protein (CRP) andp < 0.001 for IL-6). Although there was no difference between groups in terms of duration of respiratory support, mean duration of hospitalization, as well as mortality rate were significantly higher in Group 1 (p < 0.001, p < 0.05, respectively). Conclusions: Women diagnosed with a high-risk pregnancy should be treated with antibiotics immediately after a positive cervical culture result, and delivery should be delayed until the success of antibiotic treatment can be evaluated. Early initiation of maternal antibiotic therapy is associated with shorter durations of hospital stay for newborns. Close follow-up of mothers with high-risk pregnancies and extension of treatment duration are critical for determining prognosis in newborn infants.
    Preview · Article · Sep 2015 · Clinical and experimental obstetrics & gynecology
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    ABSTRACT: Purpose of investigation: Few studies have been conducted to investigate drug effects on spontaneous abortion risk. The objective of the present study was to evaluate the potential association between first trimester drug exposure and spontaneous abortion occurrence. Materials and methods: The authors performed a nested case-control study using data from TERAPPEL, a French medical database. Cases were the women who had a spontaneous abortion (before the 22nd week of amenorrhea) and controls were women who gave birth to a child. Analyzed variables were: maternal age, obstetric history, tobacco, and alcohol and drug consumption during the first trimester of pregnancy. For comparison of drug exposures between cases and controls, the authors calculated odds ratios (ORs) by means of multivariate logistic regressions adjusted on age and on other drug exposures. Results: The study included 838 cases and 4,508 controls that were identified in the database. In adjusted analyses, cases were more exposed than controls to "non-selective monoamine reuptake inhibitors" [OR=2.2 (CI 95% 1.5-3.3)], "antiprotozoals" [OR = 1.6 (CI 95% 1.1 - 2.5)] and "centrally acting antiobesity products" [OR = 3.4 (CI 95% 1.9 - 6.2)]. Conversely, controls were more exposed than cases to H1 antihistamines [OR = 0.6 (CI 95% 0.4 - 0.9)]. Conclusion: This exploratory study highlights some potential associations between first trimester drug exposure and risk of spontaneous abortion. Further studies have to be carried out to investigate these findings.
    No preview · Article · Sep 2015 · Clinical and experimental obstetrics & gynecology
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    ABSTRACT: Purpose: To establish serum YKL-40 concentrations in patients with endometriosis compared to age-matched healthy subjects. Materials and methods: This was a cross-sectional clinical study conducted in a tertiary care center. Demographics and serum YKL levels were determined and noted in a total of 63 cases (33 endometriosis patients, 30 healthy controls). Measurement of YKL-40 levels was made using a YKL-40 enzyme-linked immunosorbent assay (ELISA) kit according to the manufacturer's protocol. Results: The mean serum YKL-40 levels of the patient group was 106.0 +/- 15.9 (range 23.44 to 382.55) years, while the mean serum YKL-40 levels of the controls was 52.2 +/- 7.0 (range 22.35 to 160.0) years (p = 0.003). Conclusions: This is the first study evaluating serum YKL-40 levels in endometriosis. The present results indicate that YKL-40 levels were increased in patients with endometriosis compared to controls. The authors propose that circulating YKL-40 levels could be a novel biomarker for diagnosis and follow-up of endometriosis.
    No preview · Article · Sep 2015 · Clinical and experimental obstetrics & gynecology