Actas luso-españolas de neurología, psiquiatría y ciencias afines

Current impact factor: 0.00

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2016 Impact Factor Available summer 2017
2000 Impact Factor 0.302
1999 Impact Factor 0.146
1998 Impact Factor 0.013

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Other titles Actas luso-españolas de neurología, psiquiatría y ciencias afines
ISSN 0300-5062
OCLC 7533539
Material type Periodical
Document type Journal / Magazine / Newspaper

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: Use of BMT (bone marrow transplatation) has rapidly grown in the last few years. It extends to a variety of neoplastic illnesses and hematological malignancies. This procedure includes implicit appearance of many and important stressors, both physical and psychological, due to the illness and to chemotherapy treatments, among which the appearance and severe colateral effects during the stay in hospital has a special relevance. The need to consider the influency of predictive variables like, prior experiences, optimistic vs. pesimistic expectancies and the strategies of coping used in the adaptation through the treatment, are a central point in the study of the fluctuations of the different psychological responses and their interrelation with the physiology symtomatology which are present during the different phases of the process of BMT.
    No preview · Article · Sep 2013 · Actas luso-españolas de neurología, psiquiatría y ciencias afines

  • No preview · Article · Jan 2002 · Actas luso-españolas de neurología, psiquiatría y ciencias afines
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    ABSTRACT: The pharmacological treatment of serious mental disorders in the pregnancy, supposes a clinical dare by the possible repercussions on the fetus and the pregnancy: theratogenesis, perinatal syndrome or postnative sequels in the development. The electroconvulsive therapy (ECT) as much takes implicit a minimum risk for the mother as for the fetus and therefore, it must be located in the highest positions of the therapeutic decision trees. In the present article, are reviewed the consequences of the pharmacological treatment and the ECT in the serious mental disorders during the pregnancy. Is referenced to all of the pharmacological groups and with respect to the ECT: their indications, counterindications, complications and technical procedures advisables. Finally is reviewed the guide line for each syndromical group of psychiatric diseases.
    No preview · Article · Dec 2000 · Actas luso-españolas de neurología, psiquiatría y ciencias afines
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    ABSTRACT: This paper reviews preclinical research which demonstrates the involvement of the opioid system in the reinforcing effects of alcohol, and the effects of naltrexone, a long-acting, nonselective opioid receptor antagonist to reduce alcohol intake. Naltrexone (50 mg/day) may prevent the return to drinking by blocking the pleasurable effects or "high" associated with alcohol drinking, and relapse rates were reduced. The most common adverse effects reported include nausea and vomiting and it does not appear to be hepatotoxic in dosages recommend. Thus, naltrexone appears to offer significant therapeutic benefits, when used with behavioural treatment for alcohol dependent patients.
    No preview · Article · Dec 2000 · Actas luso-españolas de neurología, psiquiatría y ciencias afines
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    ABSTRACT: We present the use of risperidone as a potentiation strategy of the serotonergic antidepressants in four patients suffering from refractory obsessive-compulsive disorder. There were an important improvement in three patients. Adding risperidone to serotonergic antidepressants causes complex interactions between serotonergic, dopaminergic and noradrenergic systems, that could lay to the clinical improvement. These and other similar cases make necessary controlled studies. Adding risperidone to serotonergic antidepressants in patients suffering from refractory obsessive-compulsive disorder might be an effective strategy with low risk for secondary effects and without the presence of tics or psychotic symptoms.
    No preview · Article · Nov 1998 · Actas luso-españolas de neurología, psiquiatría y ciencias afines
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    ABSTRACT: A patient with Cushing's syndrome presented psyquiatric manifestations that were diagnosed and treated before diagnosis of Cushing's syndrome. These manifestations were unspecific, unstable and they responded to etiologic treatment but they didn't to syntomatic treatment. This case demonstrates the importance to make a through search for organic factors when there are changes in physical appearance and psyquiatric features are changing through the evolution.
    No preview · Article · Nov 1998 · Actas luso-españolas de neurología, psiquiatría y ciencias afines
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    ABSTRACT: The objective of this study was to compare, in a naturalistic setting, the efficacy and tolerability of currently available Selective Serotonin Re-uptake Inhibitors (SSRIs) and venlafaxine in out-patients from a primary psychiatric-care center. The sample was composed of 194 patients with mood disorders (major depressive disorder or dysthymic disorder according to the DSM-IV criteria) who initiated treatment either with a SSRI (fluoxetine, fluvoxamine, paroxetine, sertraline, and citalopram) or with venlafaxine. Baseline severity of the mood disorder was assessed using the Hamilton Depression Rating Scale and State-Trait Anxiety Inventory, and therapeutic response was measured with the Clinical Global Impression for Therapeutic Improvement. Tolerability was assessed by recording spontaneously reported adverse experiences. Patients were followed up for six months, with subjects made three o more intermediate visits. There were no significant differences in the efficacy of the antidepressants under study, but there were differences in the incidence and profiles of adverse events. Fluoxetine was associated with the lowest incidence of adverse effects in a logistical regression model. Particular events seemed to be associated with certain treatments; gastrointestinal discomfort (fluvoxamine), tremor (sertraline) and anticholinergic effects (venlafaxine).
    No preview · Article · Nov 1998 · Actas luso-españolas de neurología, psiquiatría y ciencias afines
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    ABSTRACT: Since the introduction of benzodiacepines in the medical practice their use has been generalized to numerous clinical situations. One of them is schizophrenia. In this article we analize the main settings for its use and the possible mechanisms of action, trying to draw some recomendations applicable to the psychiatric practice.
    No preview · Article · Nov 1998 · Actas luso-españolas de neurología, psiquiatría y ciencias afines
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    ABSTRACT: History od separation anxiety was investigated in several psychiatryc disorders and in 150 patients with panic disorder following DSM III-R criteria. Separation anxiety was reported by 15.3% of patients with panic disorder, 3.3% of the healthy control group, 13.3% of patients with major depression, 16.7% with dystymia, 13.3% with generalized anxiety and 33.3% with social phobia (p < 0.001). Separation anxiety is thus considered a common predisposing factor of anxiety and depressive disorders. Panic disorder patients with a history of separation anxiety had an earlier age at panic onset and greater comorbidity with social phobia and agoraphobia.
    No preview · Article · Nov 1998 · Actas luso-españolas de neurología, psiquiatría y ciencias afines
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    ABSTRACT: Main studies which have shown an association between the variation in apolipoprotein genes and human neuropsychological impairement are reviewed in this work. Data from literature indicate a special relevance of apolipoprotein E (ApoE) in relation to Central Nervous System (CNS) functions, basically memory. ApoE epsilon 4 is a well documented risk factor for late-onset Alzheimer's Disease (AD). Memory changes in older adults and in AD are also associated with ApoE genotype. Furthermore, ApoE may play a role in formation or degeneration of some neural structures related to memory. In some studies a relation between ApoE's alleles and cerebral vascular disorders like ischemic, haemorrhagic, Vascular (VD) and Multi-infarct (MD) Dementias is also reported. The role of the remaining apolipoproteins in cognitive impairment is still unknown, and these molecules have been considered as risk factors associated with environmental factors in CNS pathologies, essentially the vascular ones.
    No preview · Article · Nov 1998 · Actas luso-españolas de neurología, psiquiatría y ciencias afines
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    ABSTRACT: Two cases of neuroleptic malignant syndrome presented in a psychiatry inpatient unit are commented, as well as their positive evolution.
    No preview · Article · Nov 1998 · Actas luso-españolas de neurología, psiquiatría y ciencias afines
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    ABSTRACT: There are many recent epidemiological studies that find that intravenous drug users' (IDU's) performance in several measures of neuropsychological function are not the same than that of the general population, whether they are seropositive to HIV-1 infection or not. Consequently, it has been stated the need to establish appropriate norms for this population. The purpose of this study is to provide normative data on a battery of neuropsychological tests from a IDU group. This report provide normative data from a group of 116 IDU, on a battery of neuropsychological tests stratified by age group (mean = 30.9; SD = 4.5), and educational level (mean = 8; SD = 2.4). Comparisons between the means of the different groups according to age and education, and also with respect to sex are made. The analysis includes estimation of partial correlations between neuropsychological test scores and age and education. The analysis demonstrates that education is an important determinant of performance for most of these tests, while there are no differences in performance between the two age-groups. With respect to sex, females out-performed men on a measure of motor speed and coordination. This report provides norms that may be of use as a reference for clinical evaluation and research in drug user populations. It also emphasizes the need to establish normative data controlling for variables like educational level, from a population with special characteristics such as IDU population.
    No preview · Article · Nov 1998 · Actas luso-españolas de neurología, psiquiatría y ciencias afines
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    ABSTRACT: Alimentary restraint, cognitive variable related to eating behavior and obesity, is reportedly a valuable predictor for the development of therapeutic strategies. This paper addresses the relationship between maternal restraint and several psychological variables in their daughters (alexithymia, neuroticism, extraversion). From the study of 35 mother-daughter dyads it can be concluded that daughters of highly restrained mothers tend to present high scores in the Restraint scale of the Three Factor Eating Questionnaire of Stunkard and Messick, translated into Spanish and validated as Cuestionario de Conducta Alimentaria. Daughters of highle restrained mothers present also higher scores in the Neuroticism scale of the revised version of the Eysenck Personality Questionnaire. Daughters of mothers with low Restraint scores are in average higher than those of their mothers, although lower than those belonging to daughters of highle restrained mothers. Previous observations on the positive correlation between Disinhibition and Hunger of the Three Factor Eating Questionnaire are confirmed. These results add an additional risk factor for obesity (mothers with high Restraint) and contribute to delineate a set of psychometric indicators which might be useful in the diagnosis and prognosis of eating and body weight disorders.
    No preview · Article · Sep 1998 · Actas luso-españolas de neurología, psiquiatría y ciencias afines
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    ABSTRACT: Despite heterogeneous phenotype, lack of pathognomonic symptoms and great variability of symptoms during the course of the illness, functional neuroimaging studies have showed specific patterns of activation associated to particular schizophrenic symptoms or symptom dimensions. Negative symptoms have been associated to hypofrontality; auditory hallucinations seem to be related to abnormalities in brain regions involved in language and, reality distortion dimension has been associated to left temporal lobe impairments.
    No preview · Article · Sep 1998 · Actas luso-españolas de neurología, psiquiatría y ciencias afines
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    ABSTRACT: Schizophrenia, a psychiatric disease that is highly prevalent among the general population, has polymorphic clinical manifestations at onset and during its evolution. The most frequent manifestations are an abrupt onset with positive symptoms, perception and thought disorders, which were included by Kurt Schneider in the first range symptoms. However, on other occasions the onset is insidious and the so-called negative symptoms are present, resulting in clinical manifestations that are similar to the state of absence and a less favorable patient prognosis. Since the last century when Kraepelin defined early dementia, various authors have tried to explain the nature of this disease, resulting in Bleauler's definition of the fundamental symptoms. A clinical case of hebephrenic schizophrenia is presented in which disorders in thought, affect and volition predominated. We discuss the psychopathological views of less well-known, but not for that reason less important, authors, such as Guirod and Dice, and the similarities and differences between their views and current classifications.
    No preview · Article · Sep 1998 · Actas luso-españolas de neurología, psiquiatría y ciencias afines
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    ABSTRACT: The concept of autism as a fundamental symptom of schizophrenia has been lacking of psychiatric eminence in the course of time, just because of its absence of univocal sense, and its extraordinary richness, hardly to be apprehended by deterministic procedures. However, the experience which it refers to, is still present in the daily clinical practice. In its attempt of apprehend this reference, the psychopathology has developed several concepts, as diverse and unspecific as "Praecoxfeeling", "self disorders", or "contact disturbances". In this paper, we start from "Intersubjectivity" as the viewpoint from which we try to comprehend the immediate experience of the Other as a whole. Finally, our purpose would be to offer an interpretation of autism that could serve as a comprehensive substrate for many of the manifestations of the schizophrenic condition.
    No preview · Article · Sep 1998 · Actas luso-españolas de neurología, psiquiatría y ciencias afines
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    ABSTRACT: The existence of panic disorder (PD) in old population is a source of debate. This study is aimed at studying the sociodemographic and clinical characteristics of panic disorder in patients over 60 years of age seen in two outpatient psychiatric clinics. All consecutive cases of PD (DSM-III-R) who contacted with two outpatient clinics in a three-year period were assessed by the same team. Those patients aged 60 or more at the time of interview were grouped and compared with a young and adult group. PASS and Marks-Matthews' Phobia Scale were administered to the sample. Fifty-three (15.6%) out of 341 PD patients were over 60 years of age. Elderly patients reported less frequency and severity of symptoms, less comorbidity with social phobia (p < 0.01) and alcoholism disorders (p < 0.01) and more with dysthymia (p < 0.05). The elderly patients with PD reported fewer family histories of alcoholism (p < 0.05), depression (p < 0.05) and PD (p < 0.05). The rate of PD patients over 60 years of age who get in touch with outpatient psychiatric clinics is variable but not uncommon. Some clinical characteristics of PD in the elderly such as medical comorbidity and less symptom severity may enhance misdiagnosis in clinical settings.
    No preview · Article · Sep 1998 · Actas luso-españolas de neurología, psiquiatría y ciencias afines
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    ABSTRACT: Selective serotonin reuptake inhibitors (SSRI) have demonstrated to be effective, well tolerated and relatively safe drugs in cases of overdosage. However, and related to the potentiation of the serotonergic transmission elicited by them, these drugs have been associated by some authors with the possibility of causing vascular complications. Serotonin is a vasoactive substance with complex actions on vessel wall as a result of its interaction with specific receptors existing at this level. We present the case of an adolescent girl who suffered a cerebral infarction after consuming a toxic dose of paroxetine and two other products, one of them containing caffedrine and theodrenaline, and the other one a phlebotonic agent. In connection with the possible pathophysiological mecanism the implied products as well as the serotonergic vascular receptors are briefly reviewed. Finally, a reference is made to Calls syndrome as a possible entity related to the unfortunate event suffered by the patient. As a conclusion risks of the combined pharmacotherapy, especially in cases of overdosage and in child and adolescent populations, are underlined.
    No preview · Article · Sep 1998 · Actas luso-españolas de neurología, psiquiatría y ciencias afines