The American Journal of Drug and Alcohol Abuse (AM J DRUG ALCOHOL AB)

Publisher: American Academy of Psychiatrists in Alcoholism & Addictions, Informa Healthcare

Journal description

Where can you find timely discussions of topics such as... the characteristics of dually diagnosed patients drug use screening inventories the effects of age on perinatal substance abuse endogenous opiates and opiate and benzodiazepine receptors HIV infection risk behaviors and methadone treatment integrating substance abuse services with general medical care network therapy for addiction outreach engagement efforts physician unawareness of serious substance abuse sources of motivation in treatment programs substance abuse and organ transplantation transmission of parent/adult-child drinking patterns and much, much more! Focusing on the preclinical, clinical, pharmacological, administrative, and social aspects of substance misuse, this authoritative journal provides an important and stimulating exchange of ideas between the various modalities involved in the study and treatment of drug abuse and alcoholism. Comprehensive in scope, The American Journal of Drug and Alcohol Abuse deepens your understanding of subjects, including community approaches criminal laws cultural and ideological attitudes epidemiology funding sources pharmacology of misused drugs self-help techniques treatment methods and more! Interdisciplinary in its approach, The American Journal of Drug and Alcohol Abuse serves as an essential forum for established researchers and professionals in alcohol studies biostatistics criminology forensic medicine hematology law enforcement medicine neuropsychiatry nursing oncology pharmacology psychiatry psychology public health rehabilitation social and behavioral sciences social work sociology urban health policy, research, and education.

Current impact factor: 1.78

Impact Factor Rankings

2016 Impact Factor Available summer 2017
2014 / 2015 Impact Factor 1.779
2013 Impact Factor 1.47
2009 Impact Factor 1.335

Impact factor over time

Impact factor

Additional details

5-year impact 2.10
Cited half-life 7.40
Immediacy index 0.72
Eigenfactor 0.00
Article influence 0.67
Website American Journal of Drug and Alcohol Abuse, The website
Other titles The American journal of drug and alcohol abuse
ISSN 0095-2990
OCLC 1796465
Material type Periodical, Internet resource
Document type Journal / Magazine / Newspaper, Internet Resource

Publisher details

Informa Healthcare

  • Pre-print
    • Author can archive a pre-print version
  • Post-print
    • Author cannot archive a post-print version
  • Restrictions
    • 12 months embargo
  • Conditions
    • On author's personal website or institution website
    • Publisher copyright and source must be acknowledged
    • Non-commercial
    • Must link to publisher version
    • Publisher's version/PDF cannot be used
    • NIH funded authors may post articles to PubMed Central for release 12 months after publication
    • Wellcome Trust authors may deposit in Europe PMC after 6 months
  • Classification

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: Background: Characterizing methamphetamine use in relation to age, HIV serostatus and seroconversion is pertinent given the increasingly older age of the population with HIV and the intertwined epidemics of methamphetamine use and HIV. Objectives: Study aims were to investigate whether (i) methamphetamine use differs by age and HIV serostatus, and (ii) receiving an HIV diagnosis impacts methamphetamine use among younger and older persons with HIV. Methods: This study examined methamphetamine use characteristics among 217 individuals with a lifetime methamphetamine dependence diagnosis who completed an in-person study assessment. Results: Multivariable regressions revealed that HIV serostatus uniquely attenuates methamphetamine use, such that persons with HIV report a smaller cumulative quantity (β = -0.16, p = 0.01) and a fewer number of days (β = -0.18, p = 0.004) of methamphetamine use than persons without HIV. Among the HIV+ sample, all participants persisted in methamphetamine use after receiving an HIV diagnosis, with about 20% initiating use after seroconversion. Repeated measures analysis of variance indicated that density of methamphetamine use (i.e. grams per day used) was greater among the younger, relative to the older, HIV+ group (p = 0.02), and increased for both age groups following seroconversion (p < 0.001). Conclusion: These analyses indicate that although HIV serostatus may attenuate methamphetamine use behaviors, many people with HIV initiate, or persist in, methamphetamine use after receiving an HIV diagnosis. These findings raise the question of whether tailoring of prevention and intervention strategies might reduce the impact of methamphetamine and HIV across the age continuum.
    No preview · Article · Feb 2016 · The American Journal of Drug and Alcohol Abuse
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    ABSTRACT: Background: Patterns of drug use during pregnancy may be changing. Identifying changes in pregnant women’s drug use may help to target prevention and treatment. Objective: To determine the regional prevalence of drug and alcohol use among pregnant women in Southern California. Methods: This was a prospective, descriptive study conducted at a university health system’s urban and suburban ambulatory obstetric offices. Included were pregnant women of all ages and trimesters. Excluded were non-pregnant women and women who had previously presented for an obstetric appointment during the data collection time period. Women provided a urine sample as part of routine care. Liquid chromatography-tandem mass spectrometry analysis of urine was performed for detection of a pre-selected sample of drugs and for alcohol. Descriptive statistics were performed. Results: A total of 295 urine samples were included. All trimesters were represented. A total of 14.2% of urine samples were positive for at least one of the tested drugs or alcohol. Alcohol was detected in 6% of the urine samples and was the most frequently identified substance. Prescription opioid analgesics (3.7% detection rate) and marijuana (4% detection rate) were the other most frequently detected substances. Conclusions: Compared with older reports, our detection rates of prescription opioid analgesics were increased while rates of urinary alcohol detection were relatively unchanged, and detection rates of marijuana were decreased. Provider awareness of these substance detection rates may facilitate the identification of patients using these substances during pregnancy and ultimately help promote potential prevention and treatment.
    No preview · Article · Jan 2016 · The American Journal of Drug and Alcohol Abuse
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    ABSTRACT: Background: Social capital – the network of social connections that exists among people – is known to be related to depression and substance use among adults. However, little is known about these relationships among adolescents, even though this age group is vulnerable due to factors of peer pressure, family, neighborhood, and maturational changes. Objectives: To evaluate the associations among social capital, substance use disorder and depression on a sample of 17 705 respondents between the ages of 12 and 17 in the 2009 National Survey of Drug Use and Health. Methods: Structural equation modeling was used to examine social capital; responses to 48 items differentiated into two factors that measured structural social and cognitive social capital. Adolescent depression and substance use disorder were measured as past-year major depressive episodes and substance use disorder according to DSM-IV criteria. Results: Structural social capital was associated with substance use disorder (β = −0.12; p = 0.001) and depression (β = −0.19; p = 0.001). Cognitive social capital was associated with substance use disorder (β = −0.17; p = 0.001), but not with depression (β = −0.002; p > 0.005). Substance use disorder mediated the association between structural and cognitive social capital and depression (β = 0.06; p = 0.001). Conclusion: There was support for associations among youth structural and cognitive social capital, substance use disorder and depression. These findings suggest that additional research of a longitudinal nature is needed to determine causal connections among social capital, depression and substance use disorder for adolescents.
    No preview · Article · Jan 2016 · The American Journal of Drug and Alcohol Abuse
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    ABSTRACT: Background: Since the late 1980s, opioid-related morbidity and mortality in the United States has dramatically increased. This serious epidemic requires a coordinated medical, public policy, and social response. It is becoming readily apparent that widespread provision of naloxone may help to address this problem. However, because naloxone access laws vary between states, the extent of antidote dissemination may be limited by a given provider's geographic location. Objective: This review targets a physician or prescriber audience, in hopes of providing evidence for the safety and utility of naloxone, education on the baseline legal liability of naloxone provision and protections afforded by access laws, and resources for the proposal of statewide legislation to promote antidote distribution. Conclusion: Evidence suggests that naloxone administration by laypersons, pursuant to physician prescription or standing order, is safe and effective for reversal of opioid overdose. As of July 2015, 44 states and the District of Columbia have passed naloxone access laws, offering varying degrees of protections for prescribers. Although the likelihood of naloxone-related legal action may parallel that inherent to the usual practice of medicine, providers should be mindful of potential scenarios, exercise methods to mitigate risk, and appreciate the utility of comprehensive naloxone access legislation in orchestrating a coordinated response to the opioid overdose epidemic.
    No preview · Article · Jan 2016 · The American Journal of Drug and Alcohol Abuse
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    ABSTRACT: Background: Tobacco is the leading cause of preventable death in the world. Current cessation medications include nicotine replacement therapy (NRT), varenicline, and bupropion, while combination therapy primarily entails NRT with either varenicline or bupropion. However, recent studies have examined varenicline and bupropion in combination. Objectives: A systematic review assessing the efficacy and safety of combination varenicline and bupropion was conducted. Methods: PubMed and were searched using terms: “varenicline combination”, “bupropion combination”, “bupropion AND varenicline”, and “bupropion AND varenicline combination smoking cessation”, yielding four studies including 1193 total patients. Results: Combination therapy yielded greater efficacy than varenicline monotherapy in two randomized controlled trials and one retrospective outcomes study. One single-arm Phase II trial provided additional efficacy and safety data. Of the prospective trials, one displayed a greater 4-week smoking abstinence for weeks 8–11 with combination (39.8%) versus monotherapy (25.9%) (OR = 1.89; 95% CI = 1.07–3.35). The other demonstrated greater prolonged abstinence (continuous abstinence from week 2) at 12 weeks (OR = 1.49; 95% CI = 1.05–2.12) and 26 weeks (OR = 1.52; 95% CI = 1.04–2.22), though results were not significant at 52 weeks in this study. The retrospective study displayed higher success rates (continuous abstinence rates at 52 weeks) with combination varenicline and bupropion (55.0%; compared to varenicline monotherapy (32.1%), p < 0.001). Subgroup analyses suggest that this combination may be more beneficial in males and patients with higher baseline nicotine dependence. Conclusion: To the authors’ knowledge, this is the first review conducted to compile current literature on this novel pharmacotherapy combination for smoking cessation. Combination bupropion SR and varenicline displayed greater efficacy in smoking cessation than varenicline monotherapy, though further safety analysis is warranted to rule out additive psychiatric adverse effects.
    No preview · Article · Jan 2016 · The American Journal of Drug and Alcohol Abuse
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    ABSTRACT: Objectives: Bipolar disorder is associated with a very high prevalence of alcohol-related disorders. However, few studies have examined treatment in this population. Preclinical research suggests a role for the flavonoid icariin in mood and addictive disorders. In this open-label pilot study, we investigated the feasibility and safety of using icariin for persons with bipolar disorder and alcohol abuse or dependence. Methods: Ten participants with bipolar I or bipolar II disorders, currently depressed, and with active alcohol abuse or dependence were given open-label icariin of up to 300 mg/day for 8 weeks using a flexible dosing strategy. Participants were assessed using the Hamilton Rating Scale for Depression (HAMD), Quick Inventory of Depressive Symptomatology-Self Report (QIDS-SR), Hamilton Rating Scale for Anxiety (HAMA), and Young Mania Rating Scale (YMRS). Standard drinks, heavy drinking days, and drinking days were also quantified. Baseline and exit data were analyzed using the Wilcoxon Signed Rank Test. Results: We observed a significant decrease in the HAMD (p = 0.012, d = 0.8), QIDS (p = 0.017, d = 0.7), and HAMA (p = 0.005, d = 1.4) scores. Heavy drinking days (p = 0.034, d = 1.1) and standard drinks (p = 0.038, d = 0.8) also decreased significantly. Icariin was well tolerated and no participants withdrew due to side-effects. Conclusion: Results from this uncontrolled study suggest icariin may decrease depressive symptoms and reduce alcohol consumption in persons with bipolar disorder and alcohol use. Improvement in mood and alcohol use was similar to that observed in an open-label trial of naltrexone in this population. Controlled trials, but at this point not routine clinical use, of icariin seem warranted.
    No preview · Article · Jan 2016 · The American Journal of Drug and Alcohol Abuse
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    ABSTRACT: Background: Peer smoking is one of the strongest predictors of adolescent cigarette use, but less is known about whether other peer characteristics also contribute to this behavior. Objectives: This study examined the links between adolescent cigarette use and peer beliefs about smoking. It tested whether peer beliefs about smoking are associated with changes in cigarette use, whether this association is a result of changes in individual beliefs about smoking, and how beliefs inform friendship choices. Methods: Analyses drew on data collected from 29 school-based networks, each measured at five occasions as students moved from 6th through 9th grade, as part of the study of the PROSPER partnership model. Longitudinal social network models provided estimates of friendship selection and behavior for an average of 6,200 students at each measurement point and more than 9,000 students overall. Results: Peer beliefs about smoking influenced cigarette use both directly and through their impact on individual beliefs. Respondents tended to name friends whose beliefs about smoking were similar to their own, and the likelihood of being named as a friend was higher for those who reported more positive beliefs about smoking. Conclusion: The results from this study suggest that peer beliefs about smoking, in addition to peer cigarette use itself, are associated with adolescent smoking through several mechanisms. Because beliefs favorable to cigarette use are present before adolescents actually smoke, these results underscore the importance of implementing smoking prevention programs in early adolescence.
    No preview · Article · Jan 2016 · The American Journal of Drug and Alcohol Abuse

  • No preview · Article · Jan 2016 · The American Journal of Drug and Alcohol Abuse
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    ABSTRACT: Background: Driving under the influence remains a pervasive problem. Approximately 30% of those arrested for impaired driving offenses each year are repeat offenders, suggesting that current rehabilitative efforts are not sufficiently effective for reducing driving while intoxicated (DWI) recidivism. Aggression, negative affect, substance use problems, and childhood delinquency have been noted in the population of impaired drivers, but study of these variables on recidivism has been limited. Objectives: The aim of the current study was to examine the effects of aggression, negative affect, substance use problems, and childhood delinquency on DWI recidivism among first time offenders. Methods: In 1992, 6436 individuals in impaired driver programs in New York State were surveyed. A total of 3511 individuals provided names so that state driver abstracts could be reviewed in the future. A total of 2043 matches were found and 1770 remained after excluding those with previous DWI convictions. Driver records were reviewed in 2010 and 2012, providing between 18 and 20 years of follow-up. Results: During the follow-up period, 16.5% of individuals were arrested for an impaired driving offense. Multivariate analysis suggested that recidivism was a function of several problems, including: alcohol problem severity, aggression, negative affect, drug problem severity, criminal history, and childhood delinquency. Conclusion: Impaired driving programs should assess for childhood delinquency, aggressive tendencies, and negative affect as these constructs, along with substance use, are evident among impaired drivers who recidivate. Interventions addressing aggression and negative affect may ultimately prove useful in reducing recidivism.
    No preview · Article · Nov 2015 · The American Journal of Drug and Alcohol Abuse
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    ABSTRACT: Objective: This article reports the integration and outcomes of implementing intervention services for substance use disorder (SUD) in three New York City public sexually transmitted disease (STD) clinics. Methods: The screening, brief intervention, and referral to treatment (SBIRT) service model was implemented in the STD clinics in 2008. A relational database was developed, which included screening results, service dispositions, face-to-face interviews with 6-month follow-ups, and treatment information. Results: From February 2008 to the end of September 2012, 146 657 STD clinic patients 18 years or older were screened for current or past substance use disorders; 15 687 received a brief intervention; 954 received referrals to formal substance abuse treatment; 2082 were referred to substance abuse support services such as Alcoholics Anonymous (AA), and 690 were referred to mental health, social or HIV awareness services. Intervention services delivered through SBIRT resulted in improvements in multiple outcomes at 6 month follow-up. Patients who received interventions had reduced SUD risks, fewer mental health problems, and fewer unprotected sexual contacts. Conclusion: Delivery of SUD services in a public health setting represents a significant policy and practice change and benefits many individuals whose SUDs might otherwise be overlooked. Intervention services for substance use disorder were integrated and highly utilized in the STD setting. Further research needs to focus on the long-term impact of SUD interventions in the STD setting, their cost effectiveness, and the extent they are financially sustainable under the new healthcare law.
    No preview · Article · Nov 2015 · The American Journal of Drug and Alcohol Abuse
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    ABSTRACT: Background: Alcohol-dependent individuals exhibit dissociable event-related potential (ERP) responses to alcohol-related cues. Fewer studies have examined if similar effects can be found in non-dependent young adults who binge drink. Objectives: To delineate the neurocognitive correlates of inhibiting behavioral responses to alcoholic and non-alcoholic beverage cues in social drinkers with differing numbers of binge episodes and instances of intoxication. Methods: ERP data were acquired while 50 participants performed a Go/No-go paradigm consisting of shapes and pictures of alcoholic and non-alcoholic beverages. Behavioral and self-report data were also collected. Results: We grouped participants into those with: 0 binge episodes, 1 ≤ 5 binge episodes, and ≥ 8 episodes. Across participants, alcohol images elicited reduced N200 components and a more positive late slow-wave than non-alcoholic images. While the group with the higher number of binge episodes exhibited altered N100 amplitudes and both groups of binge drinkers exhibited minor differences in P300 topography, these effects were not specifically related to processing alcohol images. However, participants with greater instances of intoxication exhibited an enhanced N200 to alcoholic stimuli compared to individuals with fewer instances of intoxication. This effect was correlated with subjective ratings of alcoholic beverage images. Conclusions: These data suggest that binge drinking, particularly more severe binge drinking, is associated with functional modifications of cortical systems related to attentional control. Further, the data suggest that young adult social drinkers with riskier patterns of alcohol use (greater instances of intoxication) require the allocation of increased cortical resources to successfully inhibit responses to alcohol-related cues.
    No preview · Article · Nov 2015 · The American Journal of Drug and Alcohol Abuse
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    ABSTRACT: Background: Opioids influence bone metabolism in several ways and osteoporosis associated with the long-term use of opioids is believed to be multifactorial. Objectives: To investigate the effect of opioid dependence on conventional and novel biochemical parameters of bone metabolism. To evaluate whether the concomitant HCV infection affects these parameters. Methods: Fifty-nine opioid-dependent subjects and 23 healthy volunteers participated in the study. Parameters of bone metabolism were determined in serum. The determined parameters were procollagen type I N-terminal propeptide (PINP), serum Beta-Crosslaps Ι (β-CTX), total calcium (Ca), inorganic phosphorus (P), parathormone (PTH) and alkaline phosphatase bone isoenzyme (ALP). Results: The results of our study show that opioid-dependent subjects exhibit higher values in those biochemical markers that are indicative of increased osteoclast activity, such as β-CTX and ALP, compared to healthy subjects. Furthermore, in opioid-dependent subjects the values of PTH were lower, while those of PINP were higher, in comparison to healthy individuals. No significant difference in the studied parameters was found when opioid-dependent subjects positive for anti-HCV antibodies were compared with opioid-dependent subjects negative for anti-HCV antibodies. Conclusion: Our findings show that there is increased bone turnover (bone metabolism) in opioid-dependent subjects, compared to healthy individuals. Future research on bone mineral density in these patients will help us evaluate whether the bone remodeling process is balanced or not.
    No preview · Article · Nov 2015 · The American Journal of Drug and Alcohol Abuse

  • No preview · Article · Jun 2015 · The American Journal of Drug and Alcohol Abuse
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    ABSTRACT: Abstract Background: Co-occurring drug use disorders are under-detected in psychiatrically ill populations highlighting the need for more efficient screening tools. Objectives: This study compares a single-item screening tool, previously validated in a primary care setting, to the 10-item Drug Abuse Screening Test (DAST-10) for identifying co-occurring drug use disorders among patients with severe psychiatric illness. Methods: A total of 395 patients attending a psychiatric partial hospital program completed both the single-item screen and DAST-10. A subsample of consecutive patients (n = 67) was also administered the Structure Clinical Interview for DSM-IV (SCID-IV) as a diagnostic reference standard. Results: Concordance between screening measures was moderate (κ = 0.4, p < 0.01). Sensitivity and specificity of the single-item screen and DAST-10 as compared to the SCID-IV were comparable, while area under the receiver operating curve showed better discriminatory power for the identification of drug use disorders with the single-item screen. Conclusions: In comparison to the DAST-10, the single-item screen appears to be a more efficient tool to identify co-occurring drug use disorders in a psychiatric treatment setting among patients with a range of psychiatric diagnoses.
    No preview · Article · Feb 2015 · The American Journal of Drug and Alcohol Abuse