Acta gastro-enterologica Belgica (ACTA GASTRO-ENT BELG)

Publisher: Societé Royale Belge de Gastro-Entérologie

Current impact factor: 0.91

Impact Factor Rankings

2016 Impact Factor Available summer 2017
2014 / 2015 Impact Factor 0.912
2012 Impact Factor 0.581
2011 Impact Factor 0.638
2010 Impact Factor 0.648
2009 Impact Factor 1.01
2008 Impact Factor 0.832
2007 Impact Factor 1.096
2006 Impact Factor 0.736
2005 Impact Factor 0.826
2004 Impact Factor 0.713
2003 Impact Factor 0.67
2002 Impact Factor 0.636
2001 Impact Factor 0.444
2000 Impact Factor 0.605
1999 Impact Factor 0.602
1996 Impact Factor 0.182
1995 Impact Factor 0.857
1994 Impact Factor 0.87
1993 Impact Factor 0.13
1992 Impact Factor 0.059

Impact factor over time

Impact factor
Year

Additional details

5-year impact 0.86
Cited half-life 6.00
Immediacy index 0.10
Eigenfactor 0.00
Article influence 0.22
Website Acta Gastro Enterologica Belgica website
Other titles Acta gastro-enterologica belgica
ISSN 0001-5644
OCLC 1460883
Material type Periodical
Document type Journal / Magazine / Newspaper

Publications in this journal

  • [Show abstract] [Hide abstract]
    ABSTRACT: BACKGROUND: Hepatitis C virus (HCV) is one of the most noxious infectious diseases. Chronic hepatitis C (CHC) had biochemical evidence of insulin resistance (IR). The neutrophil/lymphocyte ratio (NLR) integrates information on the inflammatory milieu and physiological stress. AIM: We aimed to investigate the clinical utility of NLR to predict the presence of IR and fibrosis in CHCvirus infection. METHODS: The study included 234 CHC patients and 50 healthy controls. The CHC group was divided into two subgroups ; CHC with HOMA-IR > 3 and CHC with HOMA-IR ≤ 3. Liver biopsy, homeostasis model assessment-IR (HOMA-IR), neutrophil and lymphocyte counts were recorded ; and NLR was calculated. Proinflammatory cytokines [tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6)] were measured by an enzyme-linked immunosorbent assay. RESULTS: Patients with HOMA-IR > 3 had a higher NLR compared with patients with HOMA-IR ≤ 3 [2.61 ± 0.95 and 1.92 ± 0.86, respectively, P < 0.001]. The NLR ratio was positively correlated with HOMA-IR, C-reactive protein, TNF-α and IL-6 cytokines ; P < 0.001). Patients with advanced fibrosis (F3-4) had an elevated N/L ratio [2.4 ± 0.99] compared with patients with fibrosis stage 1-2 [1.86 ± 0.66], P < 0.001. CONCLUSIONS: The N/L ratio is higher in patients with CHC with HOMA-IR > 3 and advanced fibrosis. This ratio can be used as a novel noninvasive marker to predict IR and advanced disease. © Acta Gastro-Enterologica Belgica.
    No preview · Article · Dec 2015 · Acta gastro-enterologica Belgica
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    ABSTRACT: BACKGROUND: Obesity is an epidemic leading to high morbidity, mortality, and therefore health-related costs. Thus, there is a huge need for development of safe and effective treatments. Even though success rates of conservative methods are highly limited, the surgical approaches lead to major complications in as many as 25% of the patients. In this study, we aimed to review the currently available, less-invasive, endoscopic bariatric techniques which provides an option to reduce the risks of the patients and the medical costs. METHODS: A systematic literature review through Pubmed and Medline was performed to find the studies on this topic, and all controlled clinical trials, case reports, and case series were reviewed. RESULTS: Endoluminal bariatric interventions include restrictive, malabsorptive approaches, and other techniques including transpyloric shuttle, botulinum toxin, gastric pacing and vagal nerve stimulation. Restrictive procedures act by limiting the gastric volume and leading to early satiety, while malabsorptive procedures create a malabsorption state. Transpyloric shuttle is a device decreasing the rate of gastric emptying. Botox injection causes a delay in gastric emptying, and vagal nerve stimulation modulates eating behavior. CONCLUSION: Endoluminal bariatric techniques can become the primary choice of therapy in the near future for bariatric care.
    No preview · Article · Dec 2015 · Acta gastro-enterologica Belgica
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    ABSTRACT: Aim: The aim of this study was to investigate the clinical and pathological features of hepatic sarcoidosis in symptomatic cases. Methods: Twenty-two symptomatic hepatic sarcoidosis cases were included in the study. Hepatic sarcoidosis was determined by typical imaging, histopathology, and high angiotensin-converting enzyme levels. Demographic data, laboratory data, imaging findings, liver biopsies, and clinical findings were analyzed. Portal hypertension (PH) was defined by the presence of ascites and/or varices; imaging findings suggestive of PH-splenomegaly (> 12 cm on longest axis); portal vein dilation (> 13 mm); collateral vessel formation; and hepatic venous pressure gradient ≥ 6 mmHg. Results: Mean age was 49.63 ± 10.7 years. Liver tests showed elevated serum alkaline phosphatase and gamma-glutamyl transpeptidase levels (95%). Serum albumin levels were low (< 3 g/dl) in 32% of the patients. Histologically, hepatic granulomas were located in the portal/periportal areas, with or without parenchymal involvement (77%). Duct damage (27%), absent portal veins (32%), and hepatomegaly (41%) were also observed. Clinically, chronic cholestatic symptoms and PH features were observed in 41% and 50% of the patients, respectively. Three-quarters of patients with PH features were non-cirrhotic. Cirrhosis and bleeding varices were observed in 14%. Hepatic sarcoidosis overlaps with primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) was observed in two cases. Conclusions: Sarcoidosis causes significant hepatic disease. PH and jaundice are main clinical presentations in liver sarcoidosis patients. Imaging findings of PH should be carefully reviewed, as it can occur even before the establishment of cirrhosis. Hepatic sarcoidosis mimics and overlaps with PBC and PSC.
    No preview · Article · Oct 2015 · Acta gastro-enterologica Belgica

  • No preview · Article · Oct 2015 · Acta gastro-enterologica Belgica
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    ABSTRACT: Isolated pancreatic metastases are rare. The differential diagnosis of pancreatic neoplasms can be difficult, especially it can be troublesome to obtain tissue diagnosis. However, pancreatic lesions in patients with a history of a malignancy must be considered to be metastases. We present a case of a patient with a history of a Merkel cell carcinoma (MCC) in the neck. Twelve months after this diagnosis a follow-up CT shows a large isolated tumor in the head of the pancreas. Histological and immunohistochemical studies of specimen obtained through ultrasound-guided transabdominal biopsy, show similar characteristics as the primary MCC. To our knowledge twelve cases of a pancreatic metastasis of a MCC have been reported in English literature. A review of the literature was performed.
    No preview · Article · Oct 2015 · Acta gastro-enterologica Belgica
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    ABSTRACT: Gastric adenocarcinoma of fundic gland type [chief cell predominant type; (GA-FD-CCP)] is a rare gastric cancer variant arising from non-atrophic mucosa without Helicobacter pylori infection in the upper third portion of the stomach. GA-FD-CCP originates deep in the mucosal layer; hence, endoscopic lesion detection is often difficult at an early stage because of a minimal change in the mucosal surface. Here we present a 66-year-old man with an early stage of GA-FD-CCP showing characteristic endoscopic features. Esophagogastroduodenoscopy demonstrated a flat, slightly reddish area with black pigment dispersion and irregular micro-surface structure at the gastric fornix. The tumor was resected by endoscopic submucosal dissection and was pathologically diagnosed as GA-FD-CCP. Prussian blue staining revealed that the black pigment was a hemosiderin deposition. We reported a rare case of successfully treated GA-FD-CCP with black pigmentation that aided in early lesion detection.
    No preview · Article · Oct 2015 · Acta gastro-enterologica Belgica

  • No preview · Article · Oct 2015 · Acta gastro-enterologica Belgica

  • No preview · Article · Oct 2015 · Acta gastro-enterologica Belgica
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    ABSTRACT: A single melanocytic lesion of the esophagus should be differentiated from a primary malignant melanoma of the esophagus (PMME) or an esophageal metastatic melanoma (MME). This paper reviews the current knowledge about these entities and how to differentiate between them. Melanocytosis as a precursor of PMME is discussed as well.
    No preview · Article · Oct 2015 · Acta gastro-enterologica Belgica
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    ABSTRACT: Background and study aims: In endoscopic procedures, propofol can be safely administered either alone or in conjunction with remifentanil. The aim of the study is to compare the effects of the administration of propofol alone and the administration of remifentanil in addition to propofol on patient and endoscopist satisfaction, preoperative hemodynamic response, and propofol consumption. Materials and methods: A totally 60 patients were enrolled in the study. Propofol group (Group 1): A 0.4-mg/kg propofol bolus and 1 mg/kg/h maintenance infusion of propofol until a bispectral Indexvalueof 70-75 was achieved. Propofol + remifentanil group (Group 2) received a 0.4 mg/kg propofol bolus dose and maintained with a 0.5 mg/kg/h infusion of propofol + 0.2 mcg/kg/min infusion of remifentanil. The infusion dose of remifentanil was maintained, and the propofol infusion dose was titrated until a BIS value of 70- 75 was achieved. Results: In Group 1 (colonoscopic intervention 1 and 5 min) and Group 2 (colonoscopic intervention 10 min.), main blood pressure (MBP) value has a significant decrease. Hypotension occurred in 6 patients in group 1, while 12 patients in group 2. No significant differencewas found between the Patient’s endoscopist’ satisfaction, MBP and heart rate. Propofol consumption was greater in group 1 than in group 2. When the Ramsay sedation levels of Group 1 and Group 2 were compared, a statistically significant difference was observed. Conclusion: The addition of remifentanil to propofol may be an alternative to the use of alone propofol for sedation in colonoscopic interventions.
    No preview · Article · Oct 2015 · Acta gastro-enterologica Belgica

  • No preview · Article · Oct 2015 · Acta gastro-enterologica Belgica
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    ABSTRACT: Background and study aims : Hepatic involvement in hereditary hemorrhagic telangiectasia (HHT) is usually asymptomatic and does not require treatment. However, when present, clinical manifestations can cause considerable morbidity and mortality. Current expertise in the variable clinical manifestations and recommendations for diagnostic approach and management of hepatic involvement in HHT are outlined. Methods and materials : A review of current literature was performed using the MEDLINE search string : "Hereditary hemorrhagic telangiectasia [ALL] OR Rendu-Osler-Weber [ALL] AND (liver OR hepatic [ALL])". Results : Due to the lack of therapeutic consequence, systematic screening for hepatic involvement in asymptomatic patients with HHT is currently not recommended. In symptomatic patients, diagnostic tools include non-invasive techniques such as abdominal color Doppler ultrasound, CT and/or MRI. In any case, liver biopsy should be avoided in patients with suspected HHT because of the high bleeding risk. Liver transplantation is currently the only curative option for symptomatic hepatic involvement in HHT. Except for biliary or hepatocellular necrosis, which require urgent liver transplantation, consensus on the most appropriate timing of transplantation is lacking. Recent studies have shown a promising role for angiogenesis inhibitors as a causative treatment for hepatic involvement in HHT and its complications. Conclusions : Identification of specific risk factors for progression to the symptomatic phase is one of the main future challenges. This would subsequently allow for individualized and cost-effective screening of high-risk patients when they are still in the asymptomatic stage. However, until then screening in asymptomatic patients is not recommended. Additionally the effect of preventive measures in this high-risk population on the development of symptomatic liver involvement and on poor outcome should be established.
    No preview · Article · Oct 2015 · Acta gastro-enterologica Belgica

  • No preview · Article · Oct 2015 · Acta gastro-enterologica Belgica
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    ABSTRACT: Background/Aims: Accurate in vivo differentiation of colon polyp histology may serve to prevent the resection of diminutive hyperplastic polyps in the distal colon or the need for histologic assesment of diminutive polyps after resection. The clinical implementation of these strategies depends on the prevalence of advanced histologic findings among diminutive polyps. We aimed to determine the prevalence of advanced histologic features (villous features, high-grade dysplasia, and adenocarcinoma) in diminutive colon polyps and compare it to small and larger polyps. Patients/Methods: The data of patients who had undergone elective colonoscopy at a tertiary-care referral center were retrospectively reviewed. The size, morphology, and location of all polyps were recorded. Polyps were divided into 3 groups according to their size: diminutive (≤ 5 mm), small (6-9 mm), and large (≥ 10 mm).Results: A total of 7160 polyps in 3226 eligible patients were evaluated. The mean diameter of the polyps were 6.7 ± 4.9 mm. Histopathologic diagnosis were adenomatous in 4548 (63.5%) and non-adenomatous in 2612 (36.5%). Out of 7160 polyps, 4902 (68.5%) were diminutive (1-5 mm), 1360 (19%) were small (6-9 mm), and 898 (12.5%) large (≥ 10 mm) polyps. Among the diminutive polyps 2739 (55.9%) had adenomatous histology. There were 66 polyps (1.3%) with advanced histology in the diminutive group, 72 (5.2%) in the small group, 263 (29.2%) in the large polyp group. Diminutive polyps had a lower frequency of advanced histology compared to small and large polyps (p = 0.001). When the histology of the polyps were evaluated based on the size of the largest polyp the patient has, 2202 patients had polyp(s) ≤ 5 mm. The frequency of advanced histology was 2.2% in these patients. Conclusions: The prevalence of advanced histology in diminutive polyps is quite low (1.3%) which supports the clinical implementation of discard, resect and discard strategies in diminutive polyps.
    No preview · Article · Oct 2015 · Acta gastro-enterologica Belgica
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    ABSTRACT: Eosinophilic ascites is a very rare disorder. It can be a manifestation of the eosinophilic gastroenteritis in its serosal form or it can be secondary to infections, malignancies, vasculitis or hypereosinophilic syndrome. Among all infections, the ones produced by invasive helminth parasites should be initially suspected and ruled out. We report the case of a patient with eosinophilic ascites associated with diarrhea, abdominal pain and eosinophilia in peripheral blood. Eosinophilic colitis was also demonstrated in a colonic biopsy and empirical steroid treatment was started for suspected eosinophilic gastroenteritis. Later on, the patient improved; the ascites disappeared and the eosinophil blood count returned to normal. Subsequently, serologic testing for toxocariasis was received positive and therefore, the diagnosis of eosinophilic gastroenteritis was discarded ; albendazole was also added to treatment. The patient remained asymptomatic on follow-up. We emphasize the need to rule out parasitic infections in all patients with gastrointestinal symptoms, eosinophilia and eosinophilic infiltration of gastrointestinal tissues.
    No preview · Article · Oct 2015 · Acta gastro-enterologica Belgica
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    ABSTRACT: Background and aims: Percutaneous endoscopic gastrostomy (PEG) is insertion of a tube to stomach through abdominal wall for provision of nutrition in patients who couldn’t be fed by oral route. In the present study, it was aimed to evaluate PEG procedures performed in our facility regarding indication, complication andeffectiveness and to determine whether these characteristics have a relationship with advancing age. Material and method: In this descriptive study, we reviewed clinical and endoscopic records of 300 patients who underwent PEG procedure between May 2009 and December 2011. The patients were divided into 2 groups(group 1 > 75, group 2 < 75 years).All patients were retrospectively reviewed regarding demographicdata, indications, biochemical parameters (Hemoglobin, total protein and albumin) at baseline and 3 months after procedure,complications and mortality. Results: The most common indication for PEG was neurological (67.3%). Wound infection (6.0%) was most common early complication while tube occlusion (4.7%) was most common late complication. No significant difference was detected between groups regarding morbidity and mortality (p < 0.05). It was seen that therewere significant improvement in all biochemical parameters(p < 0.001). The most significant improvement was observed intotal protein values (p < 0.05). However, no significant difference was detected in individual parameters (p > 0.05). Conclusion: PEG should be preferred at early period in patientswho couldn’t be fed by oral route for prolonged time as it is a minimallyinvasive, simple, inexpensive, highly effective, physiologic and safe. PEG was found to have no relationship with advancing age regarding indications, morbidity, mortality rate and effectiveness.
    No preview · Article · Oct 2015 · Acta gastro-enterologica Belgica