Post-Doctoral Research Fellow - Pancreas and Biliary Cancer

Fred  Hutchinson Cancer Center is an independent, nonprofit organization  providing adult cancer treatment and groundbreaking research focused on  cancer and infectious diseases. Based in Seattle, Fred Hutch is the only  National Cancer Institute-designated cancer center in Washington.

With  a track record of global leadership in bone marrow transplantation,  HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has  earned a reputation as one of the world’s leading cancer, infectious  disease and biomedical research centers. Fred Hutch operates eight  clinical care sites that provide medical oncology, infusion, radiation,  proton therapy and related services, and network affiliations with  hospitals in five states. Together, our fully integrated research and  clinical care teams seek to discover new cures to the world’s deadliest  diseases and make life beyond cancer a reality.

At  Fred Hutch we value collaboration, compassion, determination,  excellence, innovation, integrity and respect. Our mission is directly  tied to the humanity, dignity and inherent value of each employee,  patient, community member and supporter. Our commitment to learning  across our differences and similarities make us stronger. We seek  employees who bring different and innovative ways of seeing the world  and solving problems.

The Kugel Laboratory is seeking highly motivated postdoctoral fellows interested in  exploring how the dysregulation of chromatin modifying enzymes and  developmental pathways contribute to pancreas and biliary cancer  pathogenesis and, further, whether these pathways present liabilities  that can be exploited for cancer therapy.

Applicants  are highly encouraged to submit a CV, a brief description of past  research experiences and future goals (not more than 1-2 pages).

Responsibilities

Successful  candidates will learn to generate and exploit a series of cancer model  systems including genetically engineered murine models (GEMMs),  patient-derived xenografts and novel human cancer cell lines to  understand fundamental pathogenic mechanisms underlying pancreatic  cancer. To answer these questions the laboratory uses state-of-the-art  techniques in murine models and genetics, molecular biology, cell  biology, biochemistry, metabolism, RNA profiling, proteomics,  pharmacology, genomics and computational biology.

Qualifications

MINIMUM QUALIFICATIONS:

• Recently obtained a PhD and/or MD or be nearing completion of graduate studies and have an interest in cancer research.
• Proficiency in written and verbal English.

PREFERRED QUALIFICATIONS:

• A track record of productive research is strongly preferred.
• Applicants  with specific expertise in RNA biology, biochemistry, cell biology,  cancer genomics, murine models or computational biology are highly  encouraged to apply.
• Fellowship  opportunities are available through several philanthropic and  government organizations; and recruits who join the lab will be  supported in their applications.

The  annual base salary range for this position is from $77,976 to $95,014  and pay offered will be based on experience and qualifications.