Recent publications
Background
Collaboration strategies refer to policies and practices used to align operations and services across organizations or systems. These strategies can influence implementation of cross-system interventions focused on improving integration of care, but remain under-specified and under-examined. This study identifies collaboration strategies and the conditions under which they affected implementation of Sobriety Treatment and Recovery Teams (START), an evidence-based intervention focused on integrating child welfare and behavioral health services for families involved with both systems.
Methods
Our study sample included 17 county child welfare agencies that implemented START. Data on collaboration strategies and organizational context were obtained from key informant interviews, frontline worker surveys, and contracts. Contextual data were drawn from secondary data, and fidelity data were drawn from an administrative database. Qualitative and quantitative data were integrated using coincidence analysis, and used to identify combinations of conditions that uniquely differentiated agencies with higher and lower fidelity to START.
Results
Fidelity was lower for intervention components requiring cross-system collaboration. Although key informants acknowledged the importance of collaboration for START implementation, few agencies used formal collaboration strategies other than staff co-location or reported high communication quality between frontline staff in child welfare and behavioral health. In coincidence analysis, four conditions differentiated agencies with higher and lower fidelity with 100% consistency and 88% coverage. We found that either strong leadership support or, in high need communities, third-party resource support from local behavioral health boards were sufficient for high fidelity. Similarly, in high need communities, absence of third-party resource support was sufficient for low fidelity, while in low need communities, absence of communication quality was sufficient for low fidelity.
Conclusion
Administrators, frontline workers, and interested third parties (i.e., other stakeholders not directly involved in implementation) can use collaboration strategies to facilitate implementation. However, the effectiveness of collaboration strategies depends on local context. In agencies where internal leadership support for implementation is low but need for intervention is high, third-party resource support may still be sufficient for high fidelity. Further research is needed to test effectiveness of collaboration strategies in different conditions and on a broader range of process and implementation outcomes.
Trials registration
ClinicalTrials.gov, NCT03931005, Registered 04/29/2019, https://classic.clinicaltrials.gov/ct2/show/NCT03931005.
Modularization is one of the most robust methods that industries use to profit. This technique allows Operational Research to manage complex systems by efficiently dividing them into smaller ones and thus lowering the affiliated risks and costs. Mechatronic products are complex systems associated with diverse disciplines, laborious to compose and decompose, and can benefit from modularization. In this research, Partitioning Around Medoids (PAM), Ward’s method, Divisive ANAlysis (DIANA), and Density-Based Spatial Clustering of Applications with Noise (DBSCAN) algorithms are utilized in combination with Design Structure Matrices (DSM) to cluster 175 test subjects, and their results are compared using four validation techniques. Agglomerative Coefficient (AC), Divisive Coefficient (DC), Silhouette Coefficient (SC), Composed Density between and within clusters (CDbw), and the visual inspection of two-dimensional representations of each algorithm's clustering results are the validation techniques used in this research to find the most suitable algorithm for clustering such intricate systems. Additionally, other data that emerged from this research, such as time complexity, total execution time, and average RAM usage, are also used to evaluate the overall performance of each clustering algorithm.
Dust particles are one of the most important aerosol types with various effects on atmospheric dynamics and thermodynamics, weather phenomena, atmospheric chemistry, air pollution and human health. In this study, both wind speed and direction are simulated by the WRF model in one of the dustiest cities, Zabol City, in east Iran during a 17 years period (2005-2021). The city was chosen because it’s located in a dust source and is mostly affected by local dust storms. The dust frequency is very high and at least one third of the year, dust-related codes are reported at the weather station of the city. Also, a high number of dust events occurs from May to September that is in coincidence with the Levar wind. Since both wind speed and wind direction are one of important factors in dust rising and propagation, especially near the dust sources, these parameters were simulated by WRF model in this study. WRF model well simulated both the wind direction and the wind class frequency distribution at Zabol station, while the model mostly overestimated the wind speed during the 17 years period.
Occupation-centered lifestyle interventions improve health and delay age-related declines in older adults; however, little is known about the impact of a brief telehealth lifestyle program delivered individually. This pilot investigated the Holistic Occupational Performance Empowerment (HOPE) program on occupational performance and health-related quality of life. Twelve community-dwelling older adults completed six weekly lifestyle sessions to enhance behavior change toward individualized health goals. Goal Attainment Scaling (GAS) and the Short Form 20-Item Survey (SF-20) were administered preintervention and postintervention to measure program outcomes. Among 36 health-related goals, 69.4% achieved or exceeded the expected level of attainment. A paired samples t-test revealed statistically higher posttest GAS scores compared with pretest scores, indicating significant improvements in occupational performance. SF-20 mental health scores increased postintervention, although not significantly. Preliminary findings suggest that HOPE could positively impact occupational performance in community-dwelling older adults warranting a future large-scale randomized controlled trial.
Interventions often fail to achieve long‐term behavioral maintenance. Utilizing motivational and volitional strategies to promote behavioral maintenance factors may improve this. Using a full‐factorial experiment, we tested the effects of three intervention components (focused on intrinsic motivation and identity, exercise preparation habit, and exercise instigation habit) on exercise participation over a year, among new users ( N = 751; 91% identifying as female, 54% identifying as White race) of a global, online exercise class platform, run by Les Mills International Ltd, called LM+. We also tested the intervention components' theoretical mechanisms of action—habit formation, intrinsic motivation, identity, and self‐efficacy. Multi‐level models found some support for a main effect of the exercise preparation habit intervention component in promoting self‐reported and objective exercise participation (behavioral outcomes measured via monthly surveys and the LM+ platform; mechanisms measured via monthly surveys)—in particular online exercise class frequency (fixed effect estimate = 0.84, p < 0.05, and = 0.12, p < 0.05, respectively). The preparation habit component also significantly increased preparation habit strength (0.30, p < 0.05) and instigation habit strength (0.33, p < 0.05). Other expected effects were nonsignificant. Helping individuals form an exercise preparation habit may facilitate initiating and maintaining exercise over time, in particular for attending online exercise classes, potentially through promoting greater preparation and exercise instigation habit strength.
Responsible Research and Innovation (RRI) has emerged the last decade as a prime science policy framework. The integration of RRI as a guiding framework in territorial governance has been a challenging issue for both researchers and policymakers, one that has not been sufficiently investigated, especially in the context of Transformative Innovation Policy (TIP). Whilst RRI has been mainly associated with a variety of societal actors at macro- and micro-level, there is a noticeable gap in the meso-level analysis, or at the level of territorial community systems. The objective of this article is to contribute to the emerging tendencies of fostering empirical, qualitative approaches of assessing and increasing the level of RRI embedment into territorial governance. To address this issue, RRI audits were conducted in four European territories with distinct policy foci. The audits were conducted in accordance with a three-step procedure, which commenced with a mapping of stakeholders’ interest in relation to RRI dimensions. They also sought to determine whether and how the RRI dimensions were integrated in the policy discourse. This enabled the identification of gaps in existing territorial policies and potential for integrating RRI into territorial governance to support the development of a TIP. The research findings highlighted a set of strategic policy priorities that may accelerate the implementation of a novel RRI-based governance paradigm.
This study uses topic modeling to analyze research on burnout among firefighters, police, and first responders. The corpus contains 148 abstracts and 29,517 words. Latent Dirichlet Allocation identified 8 key topics, including mental health factors like PTSD, substance abuse, and suicide, as well as organizational factors like job demands and social support. The study found limited focus on prevention and cultural nuances. It proposes developing comprehensive models incorporating lesser-known factors and subtle cultural contexts to better understand and reduce burnout in these critical professions.
Direct geological information in Antarctica is limited to ice free regions along the coast, high mountain ranges, or isolated nunataks. Therefore, indirect methods are required to reveal subglacial geology and heterogeneities in crustal properties, which are critical steps toward interpreting geological history. We present a 3D crustal model of density and susceptibility distribution in the Wilkes Subglacial Basin (WSB) and the Transantarctic Mountains (TAM) based on joint inversion of airborne gravity and magnetic data. The applied “variation of information” technique enforces a coupling between inferred susceptibility and density, relating these quantities to the same gravity and magnetic sources to give an enhanced inversion result. Our model reveals a large body located in the interior of the WSB interpreted as a batholithic intrusive structure, as well as a linear dense body at the margin of the Terre Adélie Craton. Density and susceptibility relationships are used to inform the interpretation of petrophysical properties and the reconstruction of the origin of those crustal bodies. The petrophysical relationship indicates that the postulated batholitic intrusion is granitic, but independent from the Granite Harbor Igneous Complex described previously in the TAM area. Emplacement of a large volume of intrusive granites can potentially elevate local geothermal heat flow significantly. Finally, we present a new conceptual tectonic model based on the inversion results, which includes development of a passive continental margin with seaward dipping basalt horizons and magmatic underplating followed by two distinct intrusive events associated with the protracted Ross Orogen.
The humoral response is complex and involves multiple cellular populations and signaling pathways. Bacterial and viral infections, as well as immunization regimens, can trigger this type of response, promoting the formation of microanatomical cellular structures called germinal centers (GCs). GCs formed in secondary lymphoid organs support the differentiation of high‐affinity plasma cells and memory B cells. There is growing evidence that the quality of the humoral response is influenced by genetic variants. Using 12 genetically divergent mouse strains, we assessed the impact of genetics on GC cellular traits. At steady state, in the spleen, lymph nodes and Peyer's patches, we quantified GC B cells, plasma cells and follicular helper T cells. These traits were also quantified in the spleen of mice following immunization with a foreign antigen, namely, sheep red blood cells, in addition to the number and size of GCs. We observed both strain‐ and organ‐specific variations in cell type abundance, as well as for GC number and size. Moreover, we find that some of these traits are highly heritable. Importantly, the results of this study inform on the impact of genetic diversity in shaping the GC response and identify the traits that are the most impacted by genetic background.
Crossword puzzles lend themselves to mathematical inquiry. Several authors have already described the arrangement of crossword grids and associated combinatorics of answer numbers [Fer14] [Fer20] [McS16]. In this paper, we present a new graph-theoretic representation of crossword puzzle grid designs and describe the mathematical conditions placed on these graphs by well-known crossword construction conventions.
Maternal primary adrenal insufficiency (PAI) during pregnancy, due to either Addison disease (AD) or congenital adrenal hyperplasia (CAH), is rare. Only few studies have examined the subsequent important outcomes of maternal glucocorticoid and mineralocorticoid deficiencies during pregnancy upon the fetus and the neonate. Therefore, this systematic review and meta-analysis evaluated the impact of these deficiencies, with data from PubMed/Medline, Cochrane/CENTRAL, and Google Scholar. A total of 31 studies were included for qualitative analysis and 11 for quantitative analysis. Studies examining the prevalence of spontaneous abortion, preterm birth, the occurrence of small for gestational age (SGA) neonates, as well as the neonatal birth weight were included. The systematic review revealed a substantial number of spontaneous abortions, preterm births and SGA neonates in pregnant women with PAI. The meta-analysis showed a mean spontaneous abortion prevalence of 18%, 18% and 17% in women with PAI, AD or CAH, respectively. The mean preterm birth prevalence was 11% when women with AD or CAH were analyzed together, and 13% and 9% in women with AD or CAH, respectively, when these women were analyzed separately. The mean prevalence of SGA neonates was 8% when women with AD or CAH were analyzed together, and 5% and 10% in women with AD or CAH, respectively, when these women were analyzed separately. The mean fetal birth weight was within normalcy in all women with PAI, as well as in women with AD or CAH. In conclusion the executed systematic review of 31 studies followed by a meta-analysis of 11 studies in pregnant women with PAI has shown a greater prevalence of pregnancies with negative outcome (spontaneous abortion, preterm birth) and of negative fetal outcome (SGA) in women with either AD or CAH, as compared to control pregnant women.
School readiness research points to familial assets as tools for enriching home–literacy and home–school partnerships. This research informs an urgent call for reimagining educator preparedness relative to bridging students' lived experiences at home and school. Developing a multidimensional approach to effectively partnering with multilingual families that centers families as knowledge holders has potential to interrupt persistent opportunity gaps for ethnoracially and linguistically diverse learners. This conceptual paper presents a reconceptualizing of educator preparedness through what we call a home–school connection framework. This framework situates seven principal tenets—asset‐based culturally sustaining foundations, bilingual and bicultural mirrors, authentic cariño (Curry, 2021; Kwon, 2020; Martínez‐Álvarez, 2020; Valenzuela, 1999), reciprocal collaboration, anti‐bias awareness, community valuing of multicultural literature, and familial capital. This framework is applied in practice across each tenet. Preliminary findings suggest the importance of shifting dispositional stance away from educators serving families and toward educators purposefully partnering with families honoring familial engagement capital to inform multilingual multiliteracies in educational spaces.
Background
World falls guidelines recommend that hospitalised older patients receive individualised falls prevention education, yet no studies have sought older people’s feedback on how best to deliver falls prevention education in hospitals. The objective of the study was to explore the perspectives of older people and their caregivers about barriers and enablers to implementation of a tailored hospital falls education program.
Methods
A qualitative descriptive design was used. Three focus groups and 16 semi-structured interviews were conducted. A purposive sample of older people who had previous hospital admissions and caregivers of older people were selected to review a co-designed patient falls education program (the revised Safe Recovery program). They provided feedback on how to implement the program in hospital settings. Data were thematically analysed taking an deductive-inductive approach.
Results
Participants were 37 older people [female n = 24 (64.9%), age range 64 to 89 years] and nine caregivers (female n = 8). The first theme was that the Safe Recovery Program resources were of high quality, enabling strong patient engagement and increased knowledge and awareness about falls prevention in hospitals. The second theme identified practical strategies to enable program delivery in hospital wards. The key enablers identified were: timing of delivery around wellness and the patient’s mobility; tailoring messages for each older patient; key staff members being assigned to lead program delivery. Participants recommended that staff assist older patients to set appropriate behavioural goals in relation to preventing falls in hospitals. They also recommended that staff raise older patients’ confidence and motivation to take action to reduce the risk of falls. Providing resources in other languages and alternative shorter versions was recommended to enable broad dissemination.
Conclusions
Older people and their caregivers advised that implementing falls education in hospitals can be enabled by using high quality resources, delivering falls education in a timely manner and personalising the education and support to individual needs.
The purpose of this paper is to conduct a thorough investigation of a stochastic eddy-current testing problem, when the geometric parameters of the system under study are characterized by uncertainty. Focusing on the case of subsurface defect detection, we devise reliable surrogates for the quantities of interest (QoI) based on the principles of the generalized polynomial chaos (PC) and using the orthogonal matching pursuit (OMP) solver to promote sparsity in the approximate models. In addition, a variance-based approach is implemented for the sequential construction of the necessary sample set, enabling more accurate estimation of the statistical metrics without imposing additional computational overhead. Apart from quantifying the inherent uncertainty, a sensitivity analysis is performed that assesses the impact of each geometric variable on the QoI, via the computation of Sobol indices. The efficiency of the OMP-PC algorithm is demonstrated in two variants of the subsurface-discontinuity problem, yielding at the same time useful conclusions regarding the properties of the stochastic outputs.
Background
Black flies are among the most medically and veterinary important insects, as adult females of certain species are the sole vector of Onchocerca volvulus. Here, a new black fly species belonging to the subgenus Asiosimulium Takaoka & Choochote, 2005, is described and formally named as Simulium (Asiosimulium) kittipati sp. nov.
Methods
Pupae and larvae of black flies were collected from available substrates in the stream from central Thailand. Pupae were individually separated in plastic tubes and maintained until adult flies emerged. The emerged adult flies associated with their pupal exuviae and cocoon as well as mature larvae preserved in 85% ethanol were used to describe the new species based on an integrated approach of morphological examination and molecular analysis of the COI gene.
Results
The new species is characterized in the female by the medium-long sensory vesicle with a medium-sized opening apically, scutum with three faint longitudinal vittae, and the ellipsoidal spermatheca; in the male by the number of upper-eye (large) facets in 20 vertical columns and 21 horizontal rows, hind basitarsus slender, nearly parallel-sided, and median sclerite much wider and upturned apically; in the pupa by the head and thoracic integument densely covered with tiny tubercles, and the pupal gill of arborescent type with 28–30 filaments; and in the larva by the postgenal cleft deep, nearly reaching the posterior margin of the hypostoma, and dark pigmented sheath of the subesophageal ganglion. The DNA barcode successfully differentiated the new species from its congeners with an interspecific genetic divergence of 1.74–18.72%, confirming the morphological identification that the species is a new member of the subgenus Asiosimulium. Phylogenetic analyses also indicated that the new species is genetically closely related to Simulium phurueaense Tangkawanit, Wongpakam & Pramual, 2018, further supporting its morphological classification.
Conclusions
This is the ninth species assigned to the subgenus Asiosimulium within the genus Simulium Latreille, 1802. Taxonomic notes and identification keys are given to distinguish this new species from the eight known species members in its same subgenus. Additionally, a distribution map of all species members in this subgenus occurring in Thailand and other countries is provided.
Graphical abstract
Sexual conflict is widespread among sexually reproducing organisms. Phenotypic plasticity in female resistance traits has the potential to moderate the harm imposed by males during mating, yet female plasticity has rarely been explored. In this experiment, we investigated whether female seed beetles invest more in immunocompetence, measured as phenoloxidase (PO) capacity, when exposed to cues signalling a greater risk of sexual conflict. Risk perception was manipulated by housing focal individuals alone or with a companion as developing larvae, followed by exposure to a mating-free male- or female-biased social environment when adults. We predicted that females exposed to cues of increased sexual conflict would have increased PO capacity. However, PO capacity did not differ between either larval or adult social treatments. Our results suggest that females may not perceive a risk to their fitness on the basis of increased male presence or are unable to adjust this aspect of their phenotype in response to that risk.
Background
Most people diagnosed with dementia live and die in community settings. This study aimed to: (i) describe the palliative care needs of patients with dementia at commencement of community palliative care; (ii) compare palliative care needs between patients with dementia and those with lung cancer and cardiovascular disease (CVD).
Methods
This is a population-based descriptive study that involved 8,727, 7,539 and 25,279 patients who accessed community palliative care across Australia principally because of dementia, CVD and lung cancer. Patients’ functional abilities, symptom burden and clinical condition were assessed at commencement of community alliative care using five validated instruments: Resource Utilisation Groups—Activities of Daily Living, Australia-modified Karnofsky Performance Status, Symptoms Assessment Scale, Palliative Care Problem Severity Score and Palliative Care Phase. We fitted ordinal logistic regression models to examine the differences in these assessments for dementia versus CVD and lung cancer, respectively.
Results
Overall, patients with dementia generally had low levels of distress from symptoms but poor functional problems. Compared to the other two diagnostic groups, palliative care for dementia was often initiated later and with shorter contacts. Also, patients with dementia presented with poorer functional performance (adjusted OR (aOR) = 4.02, Confidence Interval (CI): 3.68 – 4.38 for dementia vs CVD; aOR = 17.59, CI: 15.92 – 19.44 for dementia vs lung cancer) and dependency (aOR = 5.68, CI: 5.28 – 6.12 for dementia vs CVD; aOR = 24.97, CI: 22.77 – 27.39 for dementia vs lung cancer), but experienced lower levels of distress and problem severity for the majority of symptoms.
Conclusion
Community palliative care is often an ideal care option for many patients, particularly for those with dementia. We call for expansion of the palliative care workforce and options for home care support to optimize accessibility of community palliative care for dementia.
Institution pages aggregate content on ResearchGate related to an institution. The members listed on this page have self-identified as being affiliated with this institution. Publications listed on this page were identified by our algorithms as relating to this institution. This page was not created or approved by the institution. If you represent an institution and have questions about these pages or wish to report inaccurate content, you can contact us here.
Information
Address
Monmouth, United States