University of Zanjan
  • Zanjān, Zanjan, Iran
Recent publications
For the first time, the current work applied fungal α-amylase treated corn starch in granular form to produce solid state malate-esterified starch (MES). The pores and channels created on the granules after the enzymatic modification could provide more possibilities for malic acid to esterify the starch, resulting in the increase of substitution degree (0.084) and reaction efficiency (86.6%) compared to NS. Based on the obtained results, the dual treatment significantly increased solubility, amylose content, and syneresis, but reduced transparency, viscosity, digestibility rate, and swelling power compared to those of NS. The occurrence of esterification onto starch chains was confirmed by FT-IR at 1720 cm-1. Other techniques including SEM, XRD, and DSC were employed to examine changes in the structure of starch granules after applying each treatment. Also, the greenness of the combined modification (score: 77) was proved by using a new methodology named Eco-Scale.
In this work, we studied the complex behaviors of the fractional‑order financial chaotic system, consisting of a simple, relatively chaotic system with two quadratic nonlinearities (QN) and a sextic nonlinearity (SN). We completed and enriched the results presented in the study of Subartini et al. (2021). As a result of this, our study focused more on the fractional order and adaptive finite‑time sliding mode control in the financial risk chaotic system. The dynamical behaviors of the financial chaotic system (FCS) with two QN and an SN were analyzed, and the stability was investigated via the Cardano method. The stability analysis showed that the real part of all the roots was negative, which confirmed the stability of the new system under the typical parameters. By using the MATLAB simulation, these properties were characterized, including the phase portraits, 0‑1 test, Poincaré map, bifurcation diagram, and Lyapunov exponent. The analysis showed that the financial risk chaotic system of fractional order was able to exhibit chaotic behavior and periodical behavior. In spite of external perturbations and uncertainty, an adaptive finite‑time sliding mode control strategy was devised to guide the states of the financial chaotic system to the origin in a finite amount of time. MATLAB phase plots were employed in this study to illustrate all the main results
The increasing role of distribution networks as an active entity in the whole power and energy system, development of a unified power flow method to provide an integrated analysis of transmission and distribution networks becomes essential. Traditional methods have not addressed the challenge of voltage security in the coordination, while disconnecting the whole distribution network is considered as a solution for preventing major issues. This paper proposes a decentralised scheme for the coordination of transmission and distribution networks while maintaining the voltage security of the whole integrated system. At the transmission level, the transmission network operator (TSO) solves a centralised optimisation problem to minimise the system load curtailment while maintaining the system security margin. The TSO communicates the required set-points in the interface with distribution grids to the distribution system operators (DSOs.) At the distribution level, the DSOs utilise their available distributed flexibilities, such as conservation voltage reduction and feeder reconfiguration, to provide the required set-points and preserve the whole system security margin, with minimum load curtailment. This decentralised optimisation scheme preserves the system security with minimum information exchange between operators, as well as minimum physical load curtailment. The distributed flexibilities of all DSOs are utilised to meet the required security margin of the whole system. The proposed TSO–DSO coordination model is applied to the IEEE 118-bus transmission network, and the 83-bus practical distribution network of Taiwan Power Company and IEEE 33-bus feeder are considered as the connected distribution networks. The results show that the distributed flexibilities are capable of reducing the system demand to preserve the desired security margin, without any need for imposing direct load curtailment.
Globally, rejuvenation of soil health is a major concern due to the continuous loss of soil fertility and productivity. Soil degradation decreases crop yields and threatens global food security. Improper use of chemical fertilizers coupled with intensive cultivation further reduces both soil health and crop yields. Plants require several nutrients in varying ratios that are essential for the plant to complete a healthy growth and development cycle. Soil, water, and air are the sources of these essential macro- and micro-nutrients needed to complete plant vegetative and reproductive cycles. Among the essential macro-nutrients, nitrogen (N) plays a significant in non-legume species and without sufficient plant access to N lower yields result. While silicon (Si) is the 2nd most abundant element in the Earth’s crust and is the backbone of soil silicate minerals, it is an essential micro-nutrient for some plants. Silicon is just beginning to be recognized as an important micronutrient to some plant species and, while it is quite abundant, Si is often not readily available for plant uptake. The manufacturing cost of synthetic silica-based fertilizers is high, while absorption of silica is quite slow in soil for many plants. Rhizosphere biological weathering processes includes microbial solubilization processes that increase the dissolution of minerals and increases Si availability for plant uptake. Therefore, an important strategy to improve plant silicon uptake could be field application of Si-solubilizing bacteria. In this review, we evaluate the role of Si in seed germination, growth, and morphological development and crop yield under various biotic and abiotic stresses, different pools and fluxes of silicon (Si) in soil, and the bacterial genera of the silicon solubilizing microorganisms. We also elaborate on the detailed mechanisms of Si-solubilizing/mobilizing bacteria involved in silicate dissolution and uptake by a plant in soil. Last, we discuss the potential of silicon and silicon solubilizing/mobilizing to achieve environmentally friendly and sustainable crop production.
Development of novel antimicrobial phytochemical-bearing nanofibrous mats could be considered as a promising strategy to overcome against antibiotic resistance in wound healing. In this work, the electrospinning process was used to successfully create novel antimicrobial nanofiber mats made of a blend of electrospun chitosan/polycaprolactone (CS/PCL) loaded with M. communis leaf extract (MCLE) (15 and 30 wt.%). Field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD) analysis, water contact angle (WCA) testing, attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy, and mechanical properties testing were applied to evaluate physicochemical properties of the nanofiber mats. The FESEM images showed uniform, bead-free, and smooth nanofiber mats with good compatibility between MCLE and polymers. Image J software was used to calculate the average diameters of nanofibrous mats, and the average diameter increased significantly as the extract concentration increased. The existence of MCLE in the nanofibrous mats was verified by ATR-FTIR spectroscopy and XRD analysis. The tensile strength of the nanofiber mats was satisfactory (6.31–12.47 MPa). The incorporation of MCLE in CS/PCL nanofibers enhanced the scaffold’s hydrophilicity, as evidenced by a reduction in contact angle. Significant reduction up to 0.5 log of both Escherichia ( E.) coli and Staphylococcus aureus count was observed upon exposure to CS/PCL nanofibers. The MCLE (15 and 30 wt.%)-incorporated CS/PCL nanofibers demonstrated a significant reduction of bacterial count up to 0.8 log for both bacteria. The results demonstrated that manufactured nanofibers could be considered as a promising dressing in wound dressing.
Morphological and molecular characterisation of a new cryptic species of Criconemoides informis group, C. neoinformis n. sp., and C. persicus n. sp., with notes on C. avicenniae Summary-Criconemoides neoinformis n. sp., a cryptic species of C. informis group, and C. persicus n. sp. were recovered from the rhizosphere of pear and grass, in Zanjan and West-Azerbijan provinces, respectively. Criconemoides neoinformis n. sp. is characterised by 522-585 μm long females, having four separated pseudolips, anteriorly flattened lip region comprised of two annuli, 57-63 retrorse with smooth to slightly crenate margins, without anastomoses, 86.9-90.4 μm long stylet, having 6-10 annuli from vulva to posterior end and tail conical rounded with two, three or multilobed terminus and presence of males. Criconemoides persicus n. sp. could be characterised by flatly rounded lip region, having fused rectangular pseudolips, 515-615 μm body length, stylet 60-65 μm, body annuli 120-132 with smooth to slightly crenate margins, without anastomoses, 9-12 annuli from vulva to posterior end and tail conical rounded with two trilobed terminus. In inferred phylogenies, these two new species clustered with known Criconemoides species in 18S, 28S, ITS and COI trees. These species are clearly separated molecularly by all the studied markers. The use of molecular markers, mainly D2-D3 expansion segment of 28S rRNA, ITS region and COI, are very promising in the case of cryptic species found in this group of nematodes. We provided molecular markers (two sequences per marker) for these new species with morphological/morphometrical data using an integrative taxonomy approach for the unequivocal identification of these species.
In this study, conventional SPR sensors based on silver (Ag)-graphene and waveguide-coupled surface plasmon resonance (WCSPR) sensors based on Ag-BFO (Bismuth Ferrite)-Ag-graphene with and without a metamaterial (Meta) layer are examined. The numerical results demonstrate a significant increase in the depth of the reflectance dip, detection accuracy, and electric field penetration depth caused by the use of the metamaterial layer in the considered structures. This effect is more significant in the WCSPR-type structure. Furthermore, adding a thin coating of titanium oxide (TiO2) to the base structures yields the best sensitivity with a minimum reflectivity (Rmin) < 0.01 and resonance angles of less than 80° for all structures. The sensitivity of considered structures such as Ag-TiO2-graphene structure are 192°/RIU, 232°/RIU for Ag-BFO-Ag-TiO2-graphene, 280°/RIU for Ag-Meta-TiO2-graphene, and 364°/RIU for Ag-BFO-Ag-Meta-TiO2-graphene. With resonance angles below 80° and Rmin < 0.02, the structures Ag-meta-TiO2-graphene and Ag-BFO-Ag-Meta-graphene acquired the most impressive sensitivity, with sensitivities and quality factors of 512°/RIU and 514°/RIU and 45.36 and 47.27, respectively. The proposed sensors can detect changes in the sensing medium as small as 0.001 RIU. Therefore, the proposed study is extremely promising and provides a new avenue in the fields of medical biology and chemistry, based on the findings achieved.
A new PEGylated redox/pH dual‐responsive dendritic prodrug (H40‐SS‐PTX/PEG) based on commercially available dendritic polyester, boltorn® H40 (H40), as starting core template was developed and characterized for tumor triggered paclitaxel delivery. The size of the nanocarrier was determined 100 nm by TEM. The results of in vitro drug release study showed that the designed prodrugs exhibit quite intelligent behavior. Thus, under normal physiological conditions (pH=7.4), a very small amount of the drug was released, while in the case of tumor tissue (pH=5.5 and 10 mM DTT) a significant percentage of the drug was released in a same time. Also, the study of the effectiveness of the prodrugs under in vitro condition showed very good results on human breast adenocarcinoma cells. These results suggest that H40‐SS‐PTX/PEG could be a promising multifunctional nanocarrier with excellent stability for safely delivering and releasing of the drug molecules inside the cancerous cells. In this work, a new PEGylated redox/pH dual‐responsive dendritic prodrug (H40‐SS‐PTX/PEG) based on commercially available dendritic polyester, boltorn® H40 (H40), was developed and characterized for tumor triggered paclitaxel delivery.
This study aims to compare three popular machine learning (ML) algorithms including random forest (RF), boosting regression tree (BRT), and multinomial logistic regression (MnLR) for spatial prediction of groundwater quality classes and mapping it for salinity hazard. Three hundred eighty-six groundwater samples were collected from an agriculturally intensive area in Fars Province, Iran, and nine hydro-chemical parameters were defined and interpreted. Variance inflation factor and Pearson’s correlations were used to check collinearity between variables. Thereinafter, the performance of ML models was evaluated by statistical indices, namely, overall accuracy (OA) and Kappa index obtained from the confusion matrix. The results showed that the RF model was more accurate than other models with the slight difference. Moreover, the analysis of relative importance also indicated that sodium adsorption ratio (SAR) and pH have the most impact parameters in explaining groundwater quality classes, respectively. In this research, applied ML algorithms along with the hydro-chemical parameters affecting the quality of ground water can lead to produce spatial distribution maps with high accuracy for managing irrigation practice.
Background Migraine is a neurological disease that has several physical and psychological complications, which is characterized by disability and impaired quality of life. Aims The aim of this study was to explore the mediating role of pain self-efficacy in the relationship between meaning of life, perceived social support, spiritual well-being and pain catastrophizing with quality of life in migraine sufferers. The relationship between these factors with quality of life (QOL) was not fully explored in migraine patients. Method This study was a correlational study of structural equations. Therefore, 300 patients with migraine who referred to one of the specialized neurological treatment centers in Zanjan in 2021 were recruited based on the inclusion criteria. Patients also completed the World Health Organization Quality of Life Scale (WHOQOL-BREF), Meaning in Life Questionnaire, Multidimensional Scale of Perceived Social Support, Spiritual Well-Being Scale, Pain Catastrophizing Scale, Pain Self-Efficacy Questionnaire. Finally, the hypotheses were then analyzed with correlation coefficient and path analysis method by using SPSS-26 and LISREL-10.2 programs. Results The results of the present study showed that pain self-efficacy has a mediating role in the relationship between meaning of life and quality of life (B = 0.015), perceived social support with quality of life (B = 0.022), spiritual well-being with quality of life (B = 0.021), as well as pain catastrophizing with quality of life (B = − 0.015). Conclusion According to the results of this study, by considering the role of self-efficacy of pain, it is possible to develop the programs to strengthen and improve the meaning of life, perceived social support, spiritual well-being and also reduce pain catastrophizing, in order to improve the quality of life of patients with migraine.
Graphene-based nanomaterials have attracted remarkable attention during the last decade in nanotechnology. In this review, we discuss the hybrid nanomaterials based on graphene oxide (GO) and nanoparticles (NPs). We review the synthesis, properties, and applications of immobilized transition metal oxide (TMO) NPs on graphene/GO. We present the TMO NPs immobilizing methods on graphene/GO using physical and chemical methods, including arc discharge, hydrothermal, green chemistry, etc. In addition, we discuss the interaction of the graphene/GO with decorated NPs as metal, n-type, and p-type material and review the physical properties of these materials. In the end, we present promising applications of the graphene/GO-NPs materials for drug delivery, antimicrobial applications, plasmonic and solar cells.
This paper presents an accurate, broadband, and low power active balun for operation in different radio frequency applications. The balun comprises a new ultra low-voltage low-power single-to-differential (STD) converter, a differential current balancer (DCB) stage for coarse tuning the phase-error (PE) and gain-error (GE) of differential signals, and cascode transistors (CT) along with common-gate-shorting technique (CGS) and a de-Q inductance at the gate for fine tuning. This new fine tuning technique reduces the PE and GE to less than 1° and 0.5 dB, respectively, and improves the stability and second-order linearity (IIP2) performance. By using center-tap inductance-capacitance-inductance T-networks (LCL-T) between DCB stage and CT, the bandwidth and the noise figure (NF) are improved, as the parasitic capacitances of DCB stage and CT are resonated out and lower noise is contributed by CT. The balun is designed using a 180-nm CMOS technology for 30–40 GHz band, with an area (including pads) of 0.65 mm². Post-layout EM (electromagnetic) simulation of the active balun illustrates a S11 below − 10 dB, a maximum single-ended (differential) voltage gain of 13 dB (19 dB), and a GE and PE less than 0.41 dB and 1° over a 3-dB bandwidth frequency from 30 to 40 GHz, respectively. A NF of 8.5–10 dB, an average IIP3 of 2.57 dBm, and an average IIP2 of 63 dBm are achieved. The proposed active balun is also designed and simulated for X- and Ku-band, indicating the active balun is suitable for microwave applications as well.
For manufacturing of clean gasoline with a lower S content (e.g., S <10 ppm), glycine-modified polyoxotungstate ((gly) 3 H[SiW 12 O 40 ]) was immobilized on cobalt ferrite (CoFe 2 O 4) nanoceramics via the sol−gel method and employed as an efficient recyclable nanocatalyst in an extractive−oxidative desulfurization (EODS) system. The synthesized (gly) 3 H-[SiW 12 O 40 ]⊂CoFe 2 O 4 nanocatalyst was characterized using Four-ier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy dispersive spectroscopy (EDS) techniques. The optimum conditions for the reaction are given as follows: 50 mL of model and real gasoline, 0.10 g of (gly) 3 H[SiW 12 O 40 ]⊂CoFe 2 O 4 nanocatalyst, 60 min reaction time, 35°C reaction temperature, 3 mL of AcOH/ H 2 O 2 (V/V ratio of 1:2) as an oxidant system, and 10 mL of CH 3 CN solvent as an extractant. Based on optimization results under the mentioned conditions and the proposed EODS system, the removal efficiency (%) of the model fuel utilizing the (gly) 3 H[SiW 12 O 40 ]⊂CoFe 2 O 4 nanocatalyst can reach 98% with stable reusability up to five times without a noticeable decrease in its catalytic activity. Correspondingly, 0.4986 ppm S content in real gasoline could decline to 0.0145 ppm with a removal yield of 96% under identical conditions. Also, the kinetics of the EODS reactions was found to be pseudo-first order, and the EODS mechanism was put forward through the generation of a peroxometalate intermediate complex with phase transfer properties. The present research shows that liquid fuels can be purified into ultralow-sulfur fuels through highly oxidative desulfurization via the (gly) 3 H[SiW 12 O 40 ]⊂CoFe 2 O 4 nanocatalyst after the EODS process.
In general, IRMOF families are the best structures for further improvements in hydrogen storage. In this work, a combined grand canonical Monte Carlo, molecular dynamics simulation, and density functional theory calculations were performed to investigate the hydrogen adsorption of functionalized-engineered isoreticular metal organic frameworks (IRMOFs). In this paper, by introducing two new structures (IRMOF-181 and IRMOF-182), the effects of pore volume and interaction energies on adsorption capacity were studied precisely. In addition, radial distribution functions were calculated to compare the models. The simulation results showed that the H2 adsorption on the IRMOF-182 was almost 1.5–2 times greater than that of the corresponding no designed IRMOF at high pressure and 77 K. This suggests that the design of IRMOFs with alkyl group is a desired strategy for H2 storage. Also, the results of electrostatic potential map illustrated that the cluster part in IRMOF-1 has more interaction with the hydrogen molecule compared to the organic linker, while in IRMOF-18, hydrogen molecules were more localized around four methyl groups on the organic linker.
Unlabelled: Glycyrrhiza glabra L., Fabaceae, or licorice has shown potential therapeutic effects on fever, gastric ulcers, hepatic disorders, and malaria. This study aimed to assess the antimalarial activity of different fractions of root extract from twelve ecotypes from Iran. In this regard, mice were then randomly divided into 8 groups of 5 mice. Four hours after mice were infected by Plasmodium berghei, they received methanolic plant extract by intraperitoneal injection. The treatment was continued for 4 consecutive days (every 24 h), then on the fifth and seventh days, blood samples were taken from the tails of the mice and the parasitic percentages were calculated by microscopy technique. In comparison to control, every analyzed ecotype has a remarkable parasite inhibitory effect, whereas the source of the root also has a drastic difference in its antimalarial effects. The highest percentage of inhibition on days 5 and 7 was subjected to the extract of Semirom ecotype with suppression of 86.37 and 83%, respectively. On the other hand, 13.21 and 9.19% parasite growth inhibition was shown in the extracts of Shahrbabak and Haji Abad, respectively. The significant difference between these 12 ecotypes was shown with Mann-Whitney U pairwise comparison to variable parasitemia day 5 and parasitemia day 7 (p < 0.001). Supplementary information: The online version contains supplementary material available at 10.1007/s43450-022-00353-8.
Background This study was conducted to investigate life table characteristics of the parasitoid species, Goniozus legneri Gordh (Hymenoptera: Bethylidae), a major gregarious larval ecto-parasitoids of the carob moth, Ectomyelois ceratoniae Zeller (Lep.: Pyralidae). Demographic parameters of G. legneri reared on two hosts, the carob moth and the flour moth, Ephestia kuehniella (Zeller) (Lepidoptera: Pyralidae), were studied under laboratory conditions using age-stage, two-sex life table. Host stage preference and the functional response of this parasitoid were also determined. Results The duration of the immature period, adult pre-ovipositional period and total pre-ovipositional period of G. legneri reared on E. kuehniella was significantly longer than that of those reared on E. ceratoniae , while fecundity and ovipositional days of the wasp were greater/longer in females reared on E. ceratoniae . There were also significant differences in intrinsic and finite rates of increase and mean generation time between wasp parasitoid reared on two hosts. Moreover, population projection indicated that the G. legneri population can grow swifter when reared on E. ceratoniae than on E. kuehniella . Based on the experiments conducted to determine the larval stage preferences of G. legneri , for both hosts, larger larvae were more preferred stages compared to smaller ones, thereby fulfilling the optimal oviposition theory. The functional responses of G. legneri to different population densities of E. kuehniella two last instar larvae were determined as type III at 25 °C and 60% RH. Conclusion The results offer valuable information on some life history attributes of G. legneri . Although G. legneri performed better on E. ceratoniae larvae than on E. kuehniella, as the use of E. ceratoniae larvae as the main host in rearing of G. legneri might be a laborious process and can increase the production costs, E. kuehniella can be used as an alternative host. Further studies are required under greenhouse and field conditions for effective use of this biocontrol agent against the carob moth.
Organic gas steam–liquid extraction by using a special home-made extraction cell followed by graphite furnace atomic absorption spectrometry was proposed for the preconcentration and determination of ultra-trace amounts of lead in rice samples. The variables influencing the organic gas steam–liquid extraction procedure including extraction solvent volume, sample solution pH, extractant agent concentration, and the extraction chamber temperature were optimized. The optimization process has been performed by employing response surface methodology based on the central composite design. The linear dynamic range was obtained 0.5–10 μgL−1 (with R2 > 0.99). The average recovery for the extraction of lead was > 90%. The developed method was validated by determining Pb2+ in a certified reference material and successfully applied to the preconcentration and determination of lead in various rice samples. The obtained results revealed that in most of the analyzed rice samples, the lead content was lower than the limit values established by INS and WHO. The proposed method bears advantages with respect to the other conventional liquid–liquid preconcentration methods. These advantages included minimal organic solvent consumption, simplicity, low cost, and high extraction recovery.
Today, spot welding plays a special role in many engineering industries. Important industries such as automobiles use this method to connect different parts of sheets in the car body. The most important part of spot welding is to ensure that the weld is healthy, and it is very important and the best way to inspect using non-destructive tests. Ultrasonic testing (UT) has a high ability to detect defects in spot welding. The present article intends to review the ultrasonic testing techniques used in spot welding. The importance of fault detection and interpretation of defect signals in the ultrasonic test and the time of obtaining the defect for this weld have been reviewed. In the present paper, most of the proposed stainless steel and aluminum sheets have been inspected by spot welding and accurate results are available. The best mechanism and method for measuring their defects according to time calculations is proposed. It is easier to detect access defect echo and way of detecting it in the experimental test. For all sheets, cracking, porosity and single pore defects have been investigated and reported. The simulation process for all defects is also classified and brought according to the defect echo time calculations to ensure the experimental method. The choice of ultrasonic testing methods in the detection of defects is a new and good method. The spot welding process depends on non-destructive testing and the capabilities and techniques of ultrasound.
We investigate the reverse saturable absorption (RSA) and optical limiting (OL) in a three-level V-type quantum system considering the effect of the spontaneously generated coherence (SGC). It is shown that in the absence of the SGC effect, the saturable absorption (SA) is dominant in the system. By taking into account the SGC effect, we prove that the SA dramatically switches to the RSA. Moreover, it is demonstrated that the OL threshold and OL efficiency can be controlled by the SGC effect. In addition, we show that the applied field properties such as detuning can modify the SGC-induced optical limiter efficiency. It is also shown an increase in the atomic density and length of the medium makes the optical limiter more efficient. The analytical calculation shows that the Kerr nonlinearity caused by the SGC effect is the main mechanism of the system evolution. Finally, the theoretical Z-scan experiment is presented to confirm the obtained results. Our proposed scheme can be useful to design controllable atomic optical limiters for optical devices with different sensitivities.
Background The reduction in phenotypic performance of a population due to mating between close relatives is called inbreeding depression. The genetic background of inbreeding depression for semen traits is poorly understood. Thus, the objectives were to estimate the effect of inbreeding and to identify genomic regions underlying inbreeding depression of semen traits including ejaculate volume (EV), sperm concentration (SC), and sperm motility (SM). The dataset comprised ~ 330K semen records from ~ 1.5K Holstein bulls genotyped with 50K single nucleotide polymorphism (SNP) BeadChip. Genomic inbreeding coefficients were estimated using runs of homozygosity (i.e., FROH > 1 Mb) and excess of SNP homozygosity (FSNP). The effect of inbreeding was estimated by regressing phenotypes of semen traits on inbreeding coefficients. Associated variants with inbreeding depression were also detected by regressing phenotypes on ROH state of the variants. Results Significant inbreeding depression was observed for SC and SM (p < 0.01). A 1% increase in FROH reduced SM and SC by 0.28% and 0.42% of the population mean, respectively. By splitting FROH into different lengths, we found significant reduction in SC and SM due to longer ROH, which is indicative of more recent inbreeding. A genome-wide association study revealed two signals positioned on BTA 8 associated with inbreeding depression of SC (p < 0.00001; FDR < 0.02). Three candidate genes of GALNTL6, HMGB2, and ADAM29, located in these regions, have established and conserved connections with reproduction and/or male fertility. Moreover, six genomic regions on BTA 3, 9, 21 and 28 were associated with SM (p < 0.0001; FDR < 0.08). These genomic regions contained genes including PRMT6, SCAPER, EDC3, and LIN28B with established connections to spermatogenesis or fertility. Conclusions Inbreeding depression adversely affects SC and SM, with evidence that longer ROH, or more recent inbreeding, being especially detrimental. There are genomic regions associated with semen traits that seems to be especially sensitive to homozygosity, and evidence to support some from other studies. Breeding companies may wish to consider avoiding homozygosity in these regions for potential artificial insemination sires.
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2,189 members
Ehsan Mahjoubi
  • Department of Animal Science
Ali Eskandari
  • Faculty of Agriculture
Farhang Razavi
  • Department of Horticulture
Khosrow Khalifeh
  • Department of Biology
Abolfazl Jalilvand
  • Department of Electrical Engineering
Boulevard of University , 45371-38791, Zanjān, Zanjan, Iran
Head of institution
Mohsen Najafian