[Show abstract][Hide abstract] ABSTRACT: Collagen atrophy is a major factor in skin ageing. A strong correlation exists between skin collagen loss and oestrogen deficiency caused by the menopause. Skin ageing is associated with a progressive increase in extensibility and a reduction in elasticity. With increasing age, the skin also becomes more fragile and susceptible to trauma, leading to more lacerations and bruising. Furthermore, wound healing is impaired in older women. Oestrogen use after the menopause increases collagen content, dermal thickness and elasticity, and it decreases the likelihood of senile dry skin. Large-scale clinical trials are necessary to help make informed recommendations about postmenopausal oestrogen use and its role in preventing skin ageing.
No preview · Article · Jul 2013 · Best practice & research. Clinical obstetrics & gynaecology
No preview · Article · Jul 2013 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
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