University of Malaga
  • Málaga, Spain
Recent publications
En este artículo se analiza la presencia de los museos pedagógicos en los congresos de la ISCHE celebrados de 2014 a 2021 así como en el SWG dedicado a Objects, Senses and the Material World of Schooling. Entre los resultados destaca la escasa la participa ción institucional de los museos pedagógicos en ISCHE. Además, hay sólo siete artículos que estudian museos pedagógicos concretos. Dado que los congresos de la ISCHE son el mayor escaparate mundial de la Historia de la Educación, la notable actividad que como colectivo estamos realizando en torno a museos pedagógicos debería tener una mayor presencia en los mismos.
The inodilator levosimendan, in clinical use for over two decades, has been the subject of extensive clinical and experimental evaluation in various clinical settings beyond its principal indication in the management of acutely decompensated chronic heart failure. Critical care and emergency medicine applications for levosimendan have included postoperative settings, septic shock, and cardiogenic shock. As the experience in these areas continues to expand, an international task force of experts from 15 countries (Austria, Belgium, China, Croatia, Finland, France, Germany, Greece, Hungary, Italy, the Netherlands, Spain, Sweden, Switzerland, and the USA) reviewed and appraised the latest additions to the database of levosimendan use in critical care, considering all the clinical studies, meta-analyses, and guidelines published from September 2019 to November 2021. Overall, the authors of this opinion paper give levosimendan a “should be considered” recommendation in critical care and emergency medicine settings, with different levels of evidence in postoperative settings, septic shock, weaning from mechanical ventilation, weaning from veno-arterial extracorporeal membrane oxygenation, cardiogenic shock, and Takotsubo syndrome, in all cases when an inodilator is needed to restore acute severely reduced left or right ventricular ejection fraction and overall haemodynamic balance, and also in the presence of renal dysfunction/failure.
Infection with Salmonella Typhimurium ( S . Typhimurium) is a common cause of food-borne zoonosis leading to acute gastroenteritis in humans and pigs, causing economic losses to producers and farmers, and generating a food security risk. In a previous study, we demonstrated that S . Typhimurium infection produces a severe transcriptional activation of inflammatory processes in ileum. However, little is known regarding how microRNAs regulate this response during infection. Here, small RNA sequencing was used to identify 28 miRNAs differentially expressed (DE) in ileum of S . Typhimurium-infected pigs, which potentially regulate 14 target genes involved in immune system processes such as regulation of cytokine production, monocyte chemotaxis, or cellular response to interferon gamma. Using in vitro functional and gain/loss of function (mimics/CRISPR-Cas system) approaches, we show that porcine miR-194a-5p (homologous to human miR-194-5p) regulates TLR4 gene expression, an important molecule involved in pathogen virulence, recognition and activation of innate immunity in Salmonella infection.
This paper presents a Distributed Model Predictive Control (DMPC)-based algorithm for distributed and coordinated voltage control of wind power plants. Under the proposed approach, voltage magnitude at the point of connection of wind power plants is optimally controlled to meet voltage requirements. In a conventional centralized approach, each wind power farm tracks the control signals set by the Transmission System Operator but DMPC responds locally to mitigate the voltage deviations without the central commands. The problem is cast as one of optimal control, which is solved at every time step by a distributed optimization. A dual decomposition scheme is proposed to solve the distributed optimization problem where the voltages magnitude of the common nodes are used as a consensus term for the coordination. In order to extend the applicability of this control, the proposed DMPC is carefully designed in such a way that it does not require any change in the inner control of the electrical machines, controls or compensators. The algorithm has been tested on an IEEE 9-bus system with two wind power plants and on an IEEE 14-bus system with three power plants. In both cases, the plants are not directly connected. Following an analysis of the achievable performance and the computational resources consumed by the local algorithm, the results of the simulations confirm that the proposed control approach is suitable for the voltage coordination of wind power plants with acceptable scalable results.
The article aims to analyse the evolution of gas companies in Spain from their starting point in the middle of the nineteenth century (when the business was limited to public lighting), up until the complexity of the present day. This process is divided into three main stages according to the general context of the sector. In each period, the profile of the companies will be established, as well as their market and the institutional constraints and strategies that were adopted by the companies to overcome those challenges. We found that most of the peculiar features of the Spanish case history were shared with other Southern European countries. Among others, we outline the delay and low dissemination, the scarcity and high cost of coal, the lack of capital, the technology and know-how and the strong presence of foreign companies.
This paper presents an analysis of a thermal zoning system integrated in a Heating, Ventilation and Air-Conditioning (HVAC) system based on an air-to-water heat pump with a ducted fan coil. Zoned systems are based on independently controlling the temperature of each of the zones of a building. When a zone is not occupied or not in demand, the control board sends a control signal to the zone's motorised damper which interrupts the airflow supply to that room. Although this control system is gaining popularity in the residential sector, the results obtained in terms of thermal comfort and energy consumptions are not evident and should be documented. Besides, the control strategy is based on an algorithm that allows acting on the heat pump, setting the set-point temperature, and on the fan-coil, setting the fan speed. Based on this, it is possible to design an algorithm to optimize the performance of the installation ensuring thermal comfort and achieving energy savings. The thermal zoning and the HVAC control system are modelled and simulated in Trnsys17 for the case of study of a residential dwelling, compared with two different configurations: a non-zoned ducted fan coil and individual fan coils. Important benefits are obtained in the evaluation of thermal comfort, with higher values of PPD in all zones. From the point of view of energy consumption, the influence of the thermal zoning on the performance of the heat pump reports important energy savings. Finally, an economic analysis results in payback periods lower than 4.9 years.
Multi-species bottom trawl fisheries are one of the human activities with a great impact on the benthic habitats and their associated biota. This study provides estimates of the bottom trawling activity (effort), catches and landings of the main commercial species as well as an estimation of the total revenue (TR) generated inside a mud volcano field located in the Spanish margin of the Gulf of Cádiz, during a time series from 2007 to 2012. To date, no studies have been carried out to analyse the temporal evolution of bottom trawling activity and TR in a mud volcano fied, or the economic consequences of possible potential bottom trawling regulation of certain sectors harbouring vulnerable and/or threatened habitats. In this study, Vessel Monitoring System data, logbooks and sales slips were used. The spatial distribution of the bottom trawling activity, catches and TR were related to the seafloor morphology and specific bottom types of the mud volcano field. During the time series, a high bottom trawling activity and associated catches was detected in flat sandy and muddy bottoms, including the Anastasya sector and between the Guadalquivir and Cádiz Diapiric Ridges. Low bottom trawling activity and catches were detected in the deepest areas but also in areas with hard and detritic bottoms such as Gazul and Chica sectors as well as in the Diapiric Ridges. A similar spatial pattern was detected for the TR asociated with these bottom trawling fisheries. An increase in bottom trawling activity was detected during the time series, mainly at the end, probably for increasing the TR and mantaining the economic profit due to the instability and increases in fuel prices and offset the increased costs. Based on the obtained information, bottom trawling regulations should be implemented in certain sectors harboring singular and/or threatened habitats and species. In some of these sectors, a low TR from bottom trawling was detected and, bottom trawling regulation may potentially have a low socioeconomic impact. This specific bottom trawling regulation could provide a sustainable balance between bottom trawling activities and habitat conservation in this mud volcano field according to the aims of the Habitats Directive (92/43/EEC) and the European Marine Strategy Framework Directive (2008/56/EEC).
The Mediterranean Basin is a heavily pressured World biodiversity hotspot. Mediterranean coastal areas are especially threatened due to tourism, inland migration and population growth, jeopardizing the remaining natural habitats. Protected areas (PAs) aim to conserve biodiversity and ecosystem services in the long term. Here, we assessed whether coastal PAs in 16 Mediterranean countries had been effective at conserving natural habitats from land development between 2000 and 2020, using a Before-After-Control-Impact design with covariates and case-control matching in R. Mediterranean coastal PAs were effective in reducing land development, with just one exception: Israel. Legally stringent reserves were generally more effective than legally lenient multiple-use PAs, with few exceptions: Albania, France and Cyprus. In a number of countries, reserves completely prevented coastal land development, which shows that reserves are a useful tool to preserve waning Mediterranean coastal habitats. Institutional, social, economic and geographic explanatory factors were analysed for PA effectiveness at country scale, but no significant results were found, suggesting high specificity of PA effectiveness.
This paper describes the set-up and results for ecosystem extent accounts at European level, developed in the context of the United Nations System of Environmental-Economic Accounting - Ecosystem Accounting (SEEA EA). These accounts inform on the opening and closing ‘stocks’ of ecosystems and provide essential geo-spatial data to support the calculation of ecosystem condition and services accounts. The paper presents the first set of ecosystem extent accounts for Europe, covering the period 2000–2018. These show that ecosystems are relatively stable at the European scale, with significant increases in Urban ecosystems and some decrease in Heathland and shrub and Grassland ecosystems. The paper demonstrates the use of a flexible geo-spatial database to gain analytical insights for different ecosystem accounting areas, using European biogeographical regions and Natura 2000 areas as examples. More detailed ecosystem extent accounts (tier II and tier III) show trends inter alia for Agro-forestry, Peat Bog, Beaches, dunes and sands as well as Salt marsh ecosystems, important for biodiversity and ecosystem services. The accounting approach presented delivers a geo-spatial data foundation that can support further ecosystem analysis and accounts. This enables the targeting of ecosystem analysis on specific geographic areas and policy instruments.
It is known that every finite group can be represented as the full group of automorphisms of a suitable compact dessin d’enfant. In this paper, we give a constructive and easy proof that the same holds for any countable group by considering non-compact dessins. Moreover, we show that any tame action of a countable group is so realisable.
Over the last decades, algorithms have been developed for checking copositivity of a matrix. Methods are based on several principles, such as spatial branch and bound, transformation to Mixed Integer Programming, implicit enumeration of KKT points or face-based search. Our research question focuses on exploiting the mathematical properties of the relative interior minima of the standard quadratic program (StQP) and monotonicity. We derive several theoretical properties related to convexity and monotonicity of the standard quadratic function over faces of the standard simplex. We illustrate with numerical instances up to 28 dimensions the use of monotonicity in face-based algorithms. The question is what traversal through the face graph of the standard simplex is more appropriate for which matrix instance; top down or bottom up approaches. This depends on the level of the face graph where the minimum of StQP can be found, which is related to the density of the so-called convexity graph.
The evolution of High-Performance Computing (HPC) platforms enables the design and execution of progressively larger and more complex workflow applications in these systems. The complexity comes not only from the number of elements that compose the workflows but also from the type of computations they perform. While traditional HPC workflows target simulations and modelling of physical phenomena, current needs require in addition data analytics (DA) and artificial intelligence (AI) tasks. However, the development of these workflows is hampered by the lack of proper programming models and environments that support the integration of HPC, DA, and AI, as well as the lack of tools to easily deploy and execute the workflows in HPC systems. To progress in this direction, this paper presents use cases where complex workflows are required and investigates the main issues to be addressed for the HPC/DA/AI convergence. Based on this study, the paper identifies the challenges of a new workflow platform to manage complex workflows. Finally, it proposes a development approach for such a workflow platform addressing these challenges in two directions: first, by defining a software stack that provides the functionalities to manage these complex workflows; and second, by proposing the HPC Workflow as a Service (HPCWaaS) paradigm, which leverages the software stack to facilitate the reusability of complex workflows in federated HPC infrastructures. Proposals presented in this work are subject to study and development as part of the EuroHPC eFlows4HPC project.
The CO2 selectivity in CO2:CH4 and CO2:N2 mixtures has been studied in carbon materials; carbon microspheres (CMSs) and carbon microfibers (CMFs). These materials have different morphologies and textural properties but with similar chemical composition, which was demonstrated by SEM, nitrogen adsorption, and XPS techniques. The isosteric enthalpy of adsorption shows that the interaction between the CO2 molecule and CMFs releases a higher energy than CMSs. CMSs have a higher surface area and thus superior CO2 adsorption only at pressures above 6 bar, for example, i) at 323 K and 1 bar, 1.43 mmol CO2 (CMFs) and 0.82 mmol CO2 (CMSs), and ii) at 323 K and 10 bar, 3.24 mmol CO2 (CMFs) and 3.70 mmol CO2 (CMSs). At 1 bar, CMFs is better than CMSs, improving it by 40 %. And at 10 bar, although CMSs adsorb more than CMFs, it is only 14 % more. In addition, CMFs have a higher microporosity, which allows them to exhibit better CO2 selectivity in CO2:CH4 mixtures, even at relatively high pressures (5.4 mmol CO2 / mmol CH4 at 298 K and 1 bar, 4.6 mmol CO2 / mmol CH4 at 323 K and 10 bar). These values are like those reported in the literature for carbon materials synthesized by more complex and expensive methods.
This paper studies the economic implications of the circular economy and recycling activities from a macroeconomic perspective. The paper incorporates the circular economy into an otherwise standard neoclassical dynamic general equilibrium linear economy model, in which the production function depends on capital, labor, and raw materials. Raw materials are a composite of natural resources (the linear economy) and recycled material (the circular economy). Waste is a function of consumption but can be incorporated back into production activities through recycling. We find the existence of a positive S-shaped relationship between the optimal recycling rate and economic development, indicating that increasing the circularity of the economy is a necessary condition to augment social welfare in a growing economy. The optimal recycling rate depends positively on the pollution damage and waste content of final consumption goods. Simulation of the model supports the existence of a steady-state Environmental Kuznets Curve (EKC) relationship between the stock of waste and the output in the presence of a circular economy. Finally, we find that while a permanent improvement in recycling technology has positive effects on output, expanding the circularity of the economy, an increase in the cost of natural material has harmful effects on output, increasing waste accumulation and reducing recycling.
Electroencephalography (EEG) is a tool that allows us to analyze brain activity with high temporal resolution. These measures, combined with deep learning and digital signal processing, are widely used in neurological disorder detection and emotion and mental activity recognition. In this paper, a new method for mental activity recognition is presented: instantaneous frequency, spectral entropy and Mel-frequency cepstral coefficients (MFCC) are used to classify EEG signals using bidirectional LSTM neural networks. It is shown that this method can be used for intra-subject or inter-subject analysis and has been applied to error detection in musician performance reaching compelling accuracy.
This research studied the hydration of C3S-C3A-calcium sulfate systems made of combinations of two C3S (pure triclinic and Al-doped monoclinic), two C3A (pure cubic C3A and Na-doped orthorhombic), and two calcium sulfates (gypsum and hemihydrate). For each system, the hydration of four different SO3 contents (0.25-2.0 wt%) was assessed by calorimetry. The optimum SO3 content was fixed from calorimetry results, and the mixtures were evaluated by in-situ XRD and TGA. The type of C3S was the factor that most affected the sulfate balance of the systems. The mixes with Al-C3S produced a higher amount of ettringite in the first hours, resulting in much earlier sulfate depletions when compared to the mixes with pure C3S. The mixes with ort-C3A also showed faster sulfate depletion due to its higher reactivity compared with cb-C3A. Finally, the replacement of gypsum by hemihydrate resulted in faster sulfate depletion caused by the faster hemihydrate dissolution.
Nowadays, in the residential sector, a widely used Heating, Ventilation and Air Conditioning system is the ducted direct expansion inverter system based on the on/off control of a single zone, which cannot guarantee the thermal comfort in each room of the building. As a solution, the standard EN 15,232 regulates the use of control systems including thermal zoning as a fundamental condition in the energy efficiency in buildings. The zoning system can adapt the equipment working regime to meet the thermal demand in each zone monitoring the air temperature according to users’ preferences ensuring the thermal comfort in each zone. Framed in this goal, in contrast to complex and costly control systems, this paper presents a new zoned control system based on thermostats and motorized dampers in each zone, a control board and a communication gateway which allows the communication between the unit and the control board to set operational parameters as the speed of the fan or the supply air set point temperature. The practical feasibility of this new control system is presented with a thermo-economic comparison analysis with respect the conventional in the context of the Building Research Establishment Environmental Assessment Methodology certification scheme. The model of the zoning system together with implemented control algorithms is developed in TRNSYS17 and the case of study is a residential dwelling in three different Spanish cities. The results show how the thermal zoning control contributes to adapt the thermal energy to each zone in a more efficient way. Moreover, the regulation of the motorized dampers, fan speed and set point temperature of the unit ensures the thermal comfort in all the zones of the building guaranteeing a category B according to the standard regulations. Finally, from the point of view of energy consumption, energy savings from 21 to 42% are obtained, resulting in payback periods of the installation from 3.2 to 4.3 years.
Background Although there is broad agreement that perceived risks determine risk-taking behavior, previous research has shown that this association may not be as straightforward as expected. The main objective of this study was to investigate if the levels of impulsivity can explain part of these controversial findings. Method A total of 1579 participants (Mage = 23.06, from 18 to 60 years; 69.4% women) were assessed for levels of risk perception, risk-taking avoidance, and impulsivity. Results The results showed that while impulsivity was significantly and negatively related to both risk perception and risk-taking avoidance, the relationship with risk-taking avoidance was significantly stronger than with risk perception. The levels of impulsivity predicted risk-taking avoidance even when controlling for risk perception. Conclusions These findings indicate that impulsivity can differentially affect risk perception and risk-taking. We propose that the stronger influence of impulsivity on risk-taking is due to the greater reliance of risk-taking, compared with risk perception, on automatic processes guided by impulses and emotions.
Alcohol Use Disorder (AUD) is among the most prevalent mental illnesses, and due to the low efficacy of the current medication, it is essential to find new biological targets that could modulate alcohol consumption. Since Galanin (1−15) [GAL(1−15)] produces a loss of motivational behaviour by an artificial reinforcer and decreases the preference an alcohol consumption in a voluntary alcohol intake, we have studied the role of GAL(1−15) in alcohol-seeking behaviour and the involvement of the corticomesolimbic system as well as the role of GAL(1−15) in context-induced alcohol relapse. In rats, we have studied GAL(1−15)-effects on alcohol-seeking in self-administration, in fixed-ratio (FR1) and progressive-ratio (PR), and the involvement of GAL receptors using siRNA GALR1 or GALR2 knockdown animals. We have analysed the transcriptional changes of C-Fos, dopamine receptors, GAL receptors and 5HT1A receptors in the corticomesolimbic system. Also, we have examined the effect of GAL(1−15) in context-induced alcohol relapse. GAL(1−15) substantially reduced alcohol-seeking behaviour in the operant self-administration model in an FR1 protocol and at the breaking point in a PR schedule. GALR1and GALR2 were involved in these effects, as indicated by the analysis by GALR2 antagonist and GALR1 and GALR2 knockdown animals. Notably, the mechanism of GAL(1−15)-mediated actions involved changes in C-Fos, Dopamine receptors and 5HT1A expression in the ventral tegmental area, accumbens nucleus and prefrontal cortex. Significantly, GAL(1−15) reduced the context-induced alcohol relapse. These results open up the possibility to use GAL(1−15) as a novel strategy in AUD.
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6,807 members
Jose Miguel Morales Asencio
  • Department of Nursing and Podiatry
Adolfo Romero
  • Department of Nursing and Podiatry
Rubén Saborido Infantes
  • Department of Computer Sciences and Languages
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Avda. Cervantes, 2, 29071, Málaga, Spain
Head of institution
José Ángel Narváez Bueno
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