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ABSTRACT: This paper presents fuzzy model-based design for control and synchronization of chaotic systems. In this framework, the chaotic systems are exactly reproduced based on a Takagi-Sugeno (T-S) fuzzy model. Then the fuzzy controllers for control and synchronization are designed using the predictive method and some new and useful criteria are derived. Finally, numerical simulations are presented to illustrate the effectiveness and feasibility of the theoretical results.
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ABSTRACT: Doxorubicin (DOX) is a potent anticancer drug; its use has been limited by its hepatotoxicity, which is due to free radicals generation. Propolis, a honeybee product very rich in flavonoids and therapeutic possibilities, has gained popularity as a food and alternative medicine. The present study treats DOX pro-oxidant effect on hepatic cells and mitochondrial functions. The prophylactic effect of propolis ethanolic extract (EEP) against DOX induced mitochondrial oxidative stress has also been investigated. We find that doxorubicin at the amount of 10mg/Kg altered liver mitochondrial functions as attested by the overproduction of superoxide anion (O2(2-)) by mitochondrial respiratory chain complex III. The hepatic tissue from DOX treated rats showed also a marked depletion in reduced GSH contents and an inhibition in (Mn-SOD), (Cu-Zn SOD) and (CAT) enzymatic activities. DOX increase cytosolic and mitochondrial lipid peroxidation as attested by the MDA content. These results are reversed after one mount per os pretreatment by EEP at the amount of 100mg/kg. Propolis polyphenolic fraction protects liver tissue from oxidative stress by protecting mitochondrial functions and reinforcement of enzymatic and non enzymatic antioxidants.
Article: Control of multi-scroll Chen system[Show abstract] [Hide abstract]
ABSTRACT: This paper investigates the chaos control problem of a new multi-scroll chaotic system. Two nonlinear control methods are studied, namely high-order and predictive types of control. The proposed methodologies offer the possibility of stabilizing unstable periodic orbits and unstable equilibrium points from the state equations. For this purpose, we apply the high-order control method for stabilizing a desired unstable periodic orbit, while the predictive control method is applied for stabilization problem of unstable equilibrium points. In particular, these approaches are effective and easy to be implemented since we only need to apply small perturbations to the system dynamics. The multi-scroll Chen system is used as representative example to show the working principle of these methods. Numerical simulation results indicate the potential engineering applications of the proposed control methods for various multi-scroll chaos-based practical applications.
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