University of Oregon

Doliolids have a unique ability to impact the marine microbial community through bloom events and filter feeding. Their predation on large eukaryotic microorganisms is established and evidence of predation on smaller prokaryotic microorganisms is beginning to emerge. We studied the association between microorganisms and wild‐caught doliolids in the Northern California Current system. Doliolids were collected during bloom events identified at three different shelf locations with variable upwelling intensity. We discovered doliolids were associated with a range of prokaryotic microbial functional groups, which included free‐living pelagic Archaea, SAR11, and picocyanobacteria. The results suggest the possibility that doliolids could feed on the smallest members of the microbial community, expanding our understanding of doliolid feeding and microbial mortality. Given the ability of doliolids to clear large portions of seawater by filtration and their high abundance in this system, we suggest that doliolids could be an important player in shaping the microbial community structure of the Northern California Current system.

In recent years, societal narratives around teens and screens have shifted significantly. First, high-profile media coverage has raised concerns over the negative impact of technology use on the mental health, well-being, and physical safety of adolescents. Consequently, this has led to restrictive approaches to implementing parental control software, age verification systems, artificial intelligence-based risk detection, and other safety mechanisms to protect teens from such harm. At the same time, recommendations regarding digital technology use have moved beyond imposing time limits to more advanced frameworks that consider active and intentional technology use. Additionally, research recommends shifting from restrictive parenting practices to include more developmentally appropriate and resilience-based approaches that empower teens as they prepare for adulthood. Yet, researchers have acknowledged that solutions towards digital inclusion cannot be “one-size-fits-all,” as individual development, family differences, and cultural norms may influence youth outcomes. Finally, we have seen more tangible efforts through human-centered design and legislative policies targeted toward making digital platforms that engage teen users more accountable for their online safety. In this chapter, we discuss these trends and raise important questions and recommendations for setting a forward-thinking agenda for future socio-technical research and practice on promoting the digital well-being and safety of teens.

The Class II NAD ⁺ riboswitch is a bacterial RNA that binds ligands containing nicotinamide. Herein, we report a fluorescence and biolayer interferometry study of riboswitch interactions with β-NMN. The results...

Herein we report the synthesis and characterization of four donor/acceptor‐fused s‐indacenes via the late‐stage oxidation of a family of unsymmetrical benzofuran/benzothiophene‐s‐indacene regioisomers. A thorough study of their properties through experimental and computational analysis has revealed the effect of asymmetry on the molecular properties associated with antiaromaticity, as well as a strong correlation between antiaromaticity and intramolecular charge transfer (ICT). The strength of the charge transfer depends on the fusion orientation of the donor and acceptor motifs relative to the s‐indacene core. The two most antiaromatic oxidized isomers exhibit strong evidence of ICT with 30 and 40 nm solvatochromic shifts.

Herein we report the synthesis and characterization of four donor/acceptor‐fused s‐indacenes via the late‐stage oxidation of a family of unsymmetrical benzofuran/benzothiophene‐s‐indacene regioisomers. A thorough study of their properties through experimental and computational analysis has revealed the effect of asymmetry on the molecular properties associated with antiaromaticity, as well as a strong correlation between antiaromaticity and intramolecular charge transfer (ICT). The strength of the charge transfer depends on the fusion orientation of the donor and acceptor motifs relative to the s‐indacene core. The two most antiaromatic oxidized isomers exhibit strong evidence of ICT with 30 and 40 nm solvatochromic shifts.

Building on the sensitization hypothesis, the present work aimed to examine how parent-adolescent conflict might be associated with heightened emotional reactivity to peer conflicts, which in turn shape the development of adolescent internalizing psychopathology. Participants were 108 Taiwanese adolescents between the ages of 18 and 19 (Mage = 18.53, SDage = 0.39; 64% female) who completed baseline assessments, 14-day daily surveys, and 6-month follow-up assessments. Emotional reactivity was measured by calculating the daily association between peer conflict and positive and negative emotions. Results indicated that greater baseline parent-adolescent conflict was associated with higher negative emotional reactivity to peer conflicts, which then predicted increased depressive symptoms and anxiety symptoms 6 months later. Moreover, greater positive emotional reactivity to peer conflicts (i.e., more declines in positive emotions in response to peer conflicts) predicted increased depressive symptoms. Thus, the findings of the current study support and extend the sensitization hypothesis and suggest that parent-adolescent conflict may contribute to family-of-origin sensitization in non-familial, interpersonal contexts. The results have key implications for understanding adolescent developmental psychopathology associated with family conflicts and emotional reactivity.

Low socioeconomic status (SES) is negatively associated with children's cognitive and academic performance, leading to long‐term educational and economic disparities. In particular, SES is a powerful predictor of executive function (EF), language ability, and academic achievement. Despite extensive research documenting SES‐related differences in these domains, our understanding of the mechanisms underlying these associations and factors that may mitigate these relationships is limited. This systematic review aimed to identify the mediators and moderators in the association of SES with EF, language ability, and academic achievement. Our synthesis revealed stress, support, stimulation, and broader contextual factors at the school‐ and neighborhood level to be important mediators and protective factors in these associations. In particular, cognitive stimulation mediated the association of SES with EF, language ability, and academic achievement. Educational expectations, classroom and school environment, and teacher–student relationships also played a key role in the association of SES with academic achievement. In addition, factors such as preschool attendance, home learning activities, and parental support buffered the association between low SES and lower cognitive and language outcomes. We discuss these findings in the context of interventions that may help to reduce SES‐related cognitive and educational disparities.

Accurate estimation of perinatal sleep is important for informing future research and multigenerational health interventions. We compared diary- and actigraphy-estimated sleep parameters during pregnancy and postpartum. We informed our interpretation of these analyses with participants’ feedback about these sleep estimation methods. This preregistered study (https://doi.org/10.17605/OSF.IO/UZFRD) included 92 English-speaking, women-identified birthing parents who completed sleep diaries and wore wrist actigraphs for 7 days during the 3rd trimester of pregnancy, 6 weeks postpartum, and 16 weeks postpartum. Sleep parameters included total sleep time (TST), sleep efficiency (SE), sleep onset latency (SOL), and wake after sleep onset (WASO). Multilevel models tested associations between diary and actigraphic sleep over time. Results indicated that diary and actigraphic sleep parameters were significantly associated over time, although actigraphic TST, SE, and SOL tended to be lower—and WASO longer—than diary estimations. WASO estimations were significantly more discrepant during 6 weeks postpartum than during the 3rd trimester or 16 weeks postpartum. Using conventional content analysis, three primary themes emerged from participants’ feedback about sleep diaries and wrist actigraphs that enriched our interpretation of multilevel model results: (1) Wearability, (2) Functionality/Ease of Use, and (3) Measurement Accuracy. This study was the first to implement a multimethod design supplemented by qualitative data to investigate not only the association between diary and actigraphic perinatal sleep, but what it is like for birthing parents to engage with these sleep estimation methods. This study has important implications for behavioral medicine research and practice with perinatal populations.

Antarctica is currently losing net mass to the ocean primarily from West Antarctica and the Antarctic Peninsula, which together hold ~5.5 m of sea level rise potential. Yet, the East Antarctic Ice Sheet stores almost ten times more ice, and its evolution contributes significant uncertainty to sea level rise projections, mainly due to insufficient process-scale observations. Here we report the collapse of the Conger–Glenzer Ice Shelf in East Antarctica that culminated with its March 2022 disintegration. We use a combination of observations to document its evolution over four stages spanning 25 years, starting 1997–2000 when small calving events isolated it from the Shackleton Ice Shelf. In 2011, it retreated from a central pinning point, followed by relative calving quiescence for a decade; the remaining ~1,200 km² of the ice shelf disintegrated over a few days in mid-March 2022. These observations of the Conger–Glenzer Ice Shelf collapse shed light on the processes involved, in particular, the impacts of ocean and atmospheric warming and extreme weather events. Ice shelf collapses, rare in the satellite record so far, have substantial implications for the stability of the Antarctic ice sheet and its contribution to future sea level rise.

Carmine is a red pigment made from dried cochineal, a scale insect that has been a source of brilliant scarlet reds in clothing and art for more than two millennia, with records dating back to 700 BC. Since the 16th century, it has been intensely traded all over the world and was one of the most important trade goods for the Spanish empire at its economic peak. Despite still being used on an industrial scale, with hundreds of metric tonnes produced annually, the exact molecular and crystal structure of the dyestuff remains undetermined. Notably, both modern-day commercial carmine and pigments prepared following historical recipes show strikingly similar diffraction patterns, indicating a common crystalline structure. Several model structures of carmine have been proposed, and so far spectroscopic measurements have hinted at a tetrameric complex containing the conjugate base of carminic acid, aluminium ions, and calcium ions. Considering its commercial and historical significance, determining the structure and composition of carmine would aid in both modern-day regulation and identification in historical samples. Here we show that the crystal structure of carmine can at last be determined using three-dimensional electron diffraction measurements. Our investigation reveals that carmine is indeed comprised of a tetrameric complex, that assembles into a nanoporous supramolecular structure with pore diameters of approximately 1.8 nm, held together by intermolecular hydrogen bonding. Our results establish a definite structure of carmine, unveiling a surprisingly complicated arrangement in a product that has been traded around the world for centuries. We anticipate that this study will prompt further investigations of age-old crystalline compounds and formulations using state-of-the-art electron crystallography methods, while also highlighting the serendipitous creation of a man-made supramolecular material that dates back thousands of years.

This paper describes the use of a highly crystalline conductive 2D copper3(hexaiminobenzene)2 (Cu3(HIB)2) as an ultrasensitive (limit of detection of 1.8 part‐per‐billion), highly selective, reversible, and low power chemiresistive sensor for nitric oxide (NO) at room temperature. The Cu3(HIB)2‐based sensors retain their sensing performance in the presence of humidity, and exhibit strong signal enhancement towards NO over other highly toxic reactive gases, such as NO2, H2S, SO2, NH3, CO, as well as CO2. Mechanistic investigations of the Cu3(HIB)2‐NO interaction through spectroscopic analyses and density functional theory revealed that the Cu‐bis(iminobenzosemiquinoid) moieties serve as the binding sites for NO sensing, while the Ni‐bis(iminobenzosemiquinoid) MOF analog shows no noticeable response to NO. Overall, these findings provide a significant advance in the development of crystalline metal‐bis(iminobenzosemiquinoid)‐based conductive 2D MOFs as highly sensitive, selective, and reversible sensing materials for the low‐power detection of toxic gases.

Objective: Simultaneous use of alcohol and cannabis is prevalent among young adults and associated with heightened risk for harms. Individuals who engage in simultaneous use report a variety of types of use occasions and risk factors driving use occasions are unique and dynamic in nature. Intervention content may thus need to adapt to address differences across occasions. As a first step toward developing momentary interventions, it is critical to identify whether and when psychosocial factors are associated with simultaneous use. The present study aimed to identify the most critical morning and afternoon risk factors for later-day simultaneous use. Method: Participants were 119 young adult college students (63% female; 73% non-Hispanic/Latinx White) who reported weekly simultaneous use at baseline. Participants completed an online baseline survey and an ecological momentary assessment protocol (eight prompts/day) across four consecutive weekends. Results: Multilevel models revealed that morning willingness to engage in simultaneous use and social motives were associated with higher odds of later-day simultaneous use. Afternoon willingness and cross-fading motives were significantly associated with higher odds of later-day use. Morning and afternoon conformity motives were associated with lower odds of use. Conclusions: Early-day willingness to use, morning social motives, and afternoon cross-fading motives were the most salient predictors of later-day simultaneous use and may serve as viable tailoring variables to incorporate in momentary interventions. As simultaneous use episodes commonly start after 9 p.m., there is a large time window in between early-day predictors and use behavior during which timely intervention content could be delivered.

Chapter 5, by Sullivan et al, discusses the complexities of the interplay of groundwater and Critical Zone dynamics. Water—and especially groundwater—is one of the “pillars” of Critical Zone functioning. Groundwater, both in the saturated and unsaturated layers, controls the dynamics of many terrestrial ecosystems and it is crucial to humans as a primary source of freshwater. Here they explore how the structure of the CZ interacts with groundwater to regulate recharge, evapotranspiration, groundwater-surface water interactions, groundwater flow paths (even km deep), chemical weathering, interbasin groundwater flow, and finally coastal and submarine groundwater discharge dynamics. Altogether they provide a holistic understanding of how CZ processes and structure help to regulate one of Earth's most vital resources.

Direct converting low concentration CO2 in industrial exhaust gases to high-value multi-carbon products via renewable-energy-powered electrochemical catalysis provides a sustainable strategy for CO2 utilization with minimized CO2 separation and purification capital and energy cost. Nonetheless, the electrocatalytic conversion of dilute CO2 into value-added chemicals (C2+ products, e.g., ethylene) is frequently impeded by low CO2 conversion rate and weak carbon intermediates’ surface adsorption strength. Here, we fabricate a range of Cu catalysts comprising fine-tuned Cu(111)/Cu2O(111) interface boundary density crystal structures aimed at optimizing rate-determining step and decreasing the thermodynamic barriers of intermediates’ adsorption. Utilizing interface boundary engineering, we attain a Faradaic efficiency of (51.9 ± 2.8) % and a partial current density of (34.5 ± 6.4) mA·cm⁻² for C2+ products at a dilute CO2 feed condition (5% CO2 v/v), comparing to the state-of-art low concentration CO2 electrolysis. In contrast to the prevailing belief that the CO2 activation step (${{CO}}_{2}+{e}^{-}+\, * \,\to {}^{ * }{CO}_{2}^{-}$) governs the reaction rate, we discover that, under dilute CO2 feed conditions, the rate-determining step shifts to the generation of *COOH (${}^{ * } {{CO}}_{2}^{-}+{H}_{2}O\to {}^{ * } {COOH}+{{OH}}^{-}({aq})$) at the Cu⁰/Cu¹⁺ interface boundary, resulting in a better C2+ production performance.

Introduction This study tests the hypothesis that self‐reported somatic symptoms are associated with biomarkers of stress, including elevated blood pressure and suppressed immune function, among Shuar adults living in the Ecuadorian Amazon. Methods Research was conducted in three Shuar communities in the Upano Valley of the Ecuadorian Amazon and included the collection of biomarkers and a structured morbidity interview. Participants self‐reported somatic symptoms such as headaches, body pain, fatigue, and other bodily symptoms. We examined whether the number of somatic symptoms reported was associated with measures of immune (Epstein–Barr virus [EBV] antibodies) and cardiovascular (blood pressure) functioning in 97 Shuar adults (37 women, 60 men; ages 18–65 years). Multivariate linear regression analyses were used to examine the relationships among somatic symptoms and stress biomarkers, controlling for age, sex, body mass index (BMI), active infection, level of education, and income. Results Controlling for relevant covariates, Shuar adults reporting the highest level of somatic symptoms (three symptoms) were more likely to exhibit elevated systolic ( β = 0.20, p = 0.04) and diastolic blood pressure ( β = 0.23, p = 0.03), in comparison to adults reporting no symptoms. Shuar adults reporting two symptoms, compared to no symptoms, were more likely to exhibit elevated EBV antibody concentrations ( β = 0.34, p = < 0.01). Conclusions These preliminary findings demonstrate that somatic symptoms reported by Shuar men and women are associated with physiological measures widely associated with chronic psychosocial stress. These findings complement the cross‐cultural literature in medical anthropology documenting the close connection between the expression of somatic symptoms and stressful life circumstances and highlight the important role that human biologists can play in exploring biocultural phenomena.