Universitas Sebelas Maret

Purpose: The many obstacles and difficulties to carry out research in the field of physical education are the gaps and urgency in this research. This study aims to investigate perceptions from lecturers regarding the conveniences and difficulties when carrying out research in physical education during COVID-19. Material and Methods: This study uses a qualitative approach with phenomenological methods through online-based in-depth interviews. Five lecturers from two universities in Indonesia and one lecturers from universities in Hungary were willing to participate in this research. The way to select them was by sending an email to their respective universities and only 10 people participated in this study. However, 4 people did not qualify because they did not have 10 years of research experience. All participants signed a consent letter to participate in this study. The interview started with explanation from participants regarding their research experiences, the conveniences and the difficulties faced when carrying out research during pandemic. After the activity was completed, the results of the interviews were collected and then a qualitative statistical analysis was carried out In this study, statistical analysis used thematic method in the form of interviews transcribed word for word.The transcripts were read repeatedly by researchers and three experts, coding and a collection of phrases were arranged into themes. Results: The findings of this study indicate that there were several conveniences in carrying out research physical education during the COVID-19 period, including the implementation can be done anywhere and anytime, cost-effective and saving time, data collection is easier and faster. Meanwhile, the difficulties were in obtaining research subjects, subjects who have inadequate technological literacy, poor internet network and inaccurate data. Conclusions: Thus, the conveniences and difficulties of carrying out research were important and must be continuously evaluated, in order to ensure the study able to conduct optimally even during the COVID-19 pandemic crisis.

To increase Covid-19 vaccine uptake and protect vulnerable people, many countries have introduced a Covid-19 passport in 2021, allowing vaccinated individuals to access indoor facilities more freely and travel to foreign countries. However, the passport has had unintended consequences as it discriminates against those who do not want to get vaccinated for medical, religious, or political reasons, or those who do not have access to vaccines. The present study (N = 678) assessed across Brazil, UK, USA, and a group of other countries, the links between political orientation, human values, and moral foundations, and attitudes towards the Covid-19 passport and whether people perceive it as a discriminatory measure. Results showed that left-wingers, typically more inclined to recognize discrimination, favor the passport more and perceive it as less discriminatory than right-wingers. This pattern remains consistent even after controlling for human values and moral foundations, independently predicting attitudes towards the passport. Overall, our findings provide novel insights into a context in which left-wingers support measures that involuntarily discriminate against certain groups.

The COVID-19 pandemic has brought the concept of a "new normal" to our daily lives and fundamentally affects how we live, learn, and work. In these extraordinary times, the quick move from traditional (face-to-face) learning to online learning is viewed as a paradigm change affecting social, economic, and ecological factors. In this vein, the current study investigates the linkages among system quality, instructor quality, campus learning climate, student satisfaction, and online learning success. We have collected questionnaire-based data from 302 students enrolled in different programs and employed the structural equation modelling (SEM) approach. The results indicate that system and instructor quality is vital in accomplishing campus learning climate and student satisfaction. Manifestly, campus learning climate and student satisfaction also significantly affect online learning success, which helps achieve institutional excellence and positive word of mouth. Virtual learning offers many technological advantages and leads to lower resource consumption than physical learning models. Enlightening the quality of education systems and instructors is crucial in producing value in modern societies for institutional superiority.

With the rapid spread of multi-drug-resistant bacteria and more infectious or aggressive variants of SARS-CoV-2, it is critical to develop drugs that can quickly adapt to evolving bacterial and viral mutations. In this study, encouraged by nature, we synthesized a series of phloroglucinol (PG) derivatives, acyl phloroglucinols (ACPLs) 2a-4c by mimicking the structure of the natural antifungal 2,4-diacetylphloroglucinol 3a (2,4-DAPG). According to the quantum chemical calculation, these compounds were expected to be exceptionally favourable for intermolecular interaction with protein receptors. Intriguingly, the in vitro study of Staphylococcus aureus (S. aureus) ATCC 25923 and Escherichia coli (E. coli) ATCC 25922, showed that the four ACPLs 3a–4a had good antibacterial activity and selectivity against gram-positive bacteria, S. aureus. These results were then supported by in silico molecular docking and molecular dynamics simulations (MDs) between these potent compounds and the S. aureus FtsA protein (PDB ID: 3WQU). Furthermore, with the aid of the knowledge base Virus-CKB along with the molecular docking study, it was found that the three ACPLs 4a–4c showed potential inhibitors against SARS-CoV-2 PLpro (PDB ID: 7CMD). Additionally, 100 ns of MDs was carried out in order to assess the stability behaviour of ACPLs at the docked site. Moreover, in silico ADME/T and drug likeness of all studied ACPLs were also predicted. Finally, shape-based screening of FDA-approved drugs was performed using the most prominent synthesized ACPLs as a template, enabling us to include several medications that could be utilized as antibacterial and antiviral drug candidates. Communicated by Ramaswamy H. Sarma

Lanthanum-substituted cobalt ferrite nanoparticles (CoLa 0.1 Fe 1.9 O 4 ) with different Fe ³⁺ cation sources i.e., using standard chemical lab (sample A) and a Bengawan Solo River fine sediment (sample B), were synthesized using the co-precipitation method. FTIR analysis showed that the absorption of the two nanoparticles sample appeared at a peak of v 1 = 586.39 cm ⁻¹ , whereas the v 2 appear at 461.97/cm and 435.93/cm respectively. It is suggested that the La ³⁺ cation has succeeded in replacing the original structure of the cobalt ferrite. X-ray diffraction analysis showed that nanoparticles produce using a standard chemical lab (sample A) have smaller crystallite sizes, D =18.16 nm than the natural source of fine sediment (sample B), D =24.56 nm, respectively. Furthermore, the VSM results showed that the magnitude coercive field of Hc = 3100 Oe and Hc = 100 Oe for samples A and B, respectively. Meanwhile, the obtained saturated magnetization Ms of 15.55 emu/g for sample A and the Ms is 58.40 emu/g for sample B. This result informs that if a hard magnetic material is desired then the use of lab raw materials is more promising, while if soft magnetic is desired then a natural source of fine sediment is more appropriate to use.

The synthesis of zinc-substituted cobalt ferrite (Co 0.9 Zn 0.1 Fe 2 O 4 ) using the sol gel method has been successfully carried out. The thermogravimetric analysis and differential thermal analyzer curve shows that at 400°C the Co 0.9 Zn 0,1 Fe 2 O 4 sample has formed the final phase of nanoparticles. Therefore, the modification of physical properties was carried out by annealing treatment at temperature of 450°C, 550°C, 650°C, and 750°C. The X-rays diffraction show that all samples are in a single phase with a face center cubic space group Fd-3m structure according to the ICDD 221086. The crystal size increased with the annealing temperature 33.69 nm to 45.88 nm. The Co 0.9 Zn 0.1 Fe 2 O 4 showed as excellent antibacterial properties on Staphylococcus aureus and Escherichia coli . The most superior antibacterial activity to Staphylococcus aureus was Co 0.9 Zn 0,1 Fe 2 O 4 sample which was annealed at 650°C with a clear zone diameter of 39.81 mm. Meanwhile, the Escherichia coli bacteria which had the most superior antibacterial activity were Co 0.9 Zn 0,1 Fe 2 O 4 samples which were annealed at 450°C with a clear zone measuring 21.04 mm.

Objectives: Infection prevention and control (IPC) in hospitals is key to safe patient care. Currently, no data are available regarding the implementation of IPC in hospitals in Indonesia. We assessed the existing IPC practices in a nationwide survey using the World Health Organization (WHO) IPC assessment framework tool (IPCAF) to identify strengths, weaknesses, and challenges. Methods: A cross-sectional study was conducted from July to November 2021. Of all general hospitals in Indonesia, 475 (20%) were selected using stratified random sampling based on class (ie, A, B, C, and D; A being the larger hospitals with ≥250 beds) and region. IPCAF was translated into Indonesian and was tested in 4 hospitals. Questions were added regarding challenges in the implementation of IPC. Introduction meetings were held online with all selected hospitals, after which the IPCAF was sent as an online questionnaire. Results: In total, 355 hospitals (74.7%) participated in this study. The overall median score of IPCAF was 632.5. The level of implementation of IPC was mostly advanced (56.9%), followed by intermediate (35.8%), basic (7.0%), and inadequate (0.3%). The core component with the highest scores was IPC guidelines; almost all hospitals had guidelines on the most important topics, including hand hygiene. Core components with the lowest scores were surveillance of healthcare-associated infections (HAIs), education and training, and multimodal strategies. Although >90% of hospitals indicated that surveillance of HAIs was performed, 57.2% reported no availability of adequate microbiology laboratory capacity to support HAI surveillance. The most reported challenges in the implementation of IPC were behavior change and lack of availability of antibiograms. Conclusions: The implementation of the IPC core components in most Indonesian hospitals was “advanced.” For surveillance of HAIs, the need for the availability and capability of the microbiology laboratory was revealed.

This research aimed to formulate priority strategies for adopting Internet of Things (IoT)-based innovation by millennial farmers in Central Java Province, Indonesia. This research uses quantitative methods. The two stages involved were exploring external factors using a political, economic, social, and technological approach and internal factors using the resource-based view approach including human resources, physical resources, and organizational resources. Interviews were conducted with 120 millennial farmers in ten regions of Central Java. This led to the formulation of alternative adoption strategies. Furthermore, the second stage was formulating strategic priorities using the analytical network process approach, involving purposively selected experts from policymakers in the government. According to the research, the most considered factors for IoT adoption strategies were relative advantage, social influence, and technology anxiety. In the relative advantage, the most prioritized sub-factor was business profit. The most prioritized technology anxiety sub-factor cluster was unfamiliar with using IoT. The most prioritized social influence sub-factor cluster was a personal relationship. The resulting strategic priorities were strengthening openness to change, IoT education to millennial farmers, optimizing the role of institutions, and socializing the benefits of IoT to millennial farmers. Openness to change motivates millennial farmers to achieve continuous and better innovation. Millennial farmers need to be prepared for the new experiences to come. Government support through education, intensive mentoring, and increasing the active role of farmer mentoring institutions accelerates the adoption of IoT by millennial farmers.

Growing potato crops at low elevation in the tropical region may face many problems related to high temperature, such as an increase in endogen GA3 levels, causing the inhibition of tuber formation. Suppressing GA3 biosynthesis, by applying a mixture of plant growth regulators (PGRs), is of important. The objectives of this experiment were to study the best PGR mixtures, PGR application time, and their interaction in promoting tuber formation at low altitude of tropical areas in Indonesia. The experiment used a completely randomized design arranged in factorial (2 factors, 3 replications). The first factor was a mix of plant growth regulator solution (M), consisting of 4 levels, which were: M0 = No PGR; M1 = 10 ppm 2,4-D + 100 ppm Daminozide, M2 = M1 +10 ppm BAP, M3 = M1 + 25 ppm COU, and M4 = M1+ 500 ppm PBZ. The second factor was application time of the solutions (T), consisting of 3 levels, which were: T1 = 3, 4, 5, 6 weeks after emergence (WAE), T2 = 3, 4, 5 WAE, and T3 = 3, 4 WAE. The results showed that all of the PGR mixtures promoted tuber formation with 10 ppm 2,4-D + 100 ppm Daminozide + 500 ppm Paclobutrazol was found as the best PGR mixture. Moreover, the best time to spray the mixture was 3,4,5,6 WAE. Finally, the best interaction between PGR and application time was10 ppm 2,4-D + 100 ppm Daminozide + 10 ppm BAP applied at 3,4,5 WAE.

Phaius tankervilleae and Phaius amboinensis orchids are decorative orchids that have high ornamental value and are classified as endangered plants. Genetic information from the P. tankervilleae and P. amboinensis orchids will be useful for plant breeders to develop a strategy in the ornamental improvement program. The aim of the study was to determine the karyotype pattern of P. tankervilleae and P. amboinensis orchids. Chromosomes obtained from meristematic root tips of each species were used to construct a karyotype and idiogram used the squash method. The results showed that the chromosome numbers and karyotype formulae of P. tankervilleae was 2n=2x=44=44 m (metacentric) and P. amboinensis was 2n=2x= 46=44m+2sm (sub-metacentric). Intrachromosomal Asymmetry Index (A1) of P. tankervillae was 0,10 and P. amboinensis was 0,15, indicates that both of them tend to have a metacentric chromosome type. Interchromosomal Asymmetry Index (A2) of P. tankervillae was 0,37 and P. amboinensis was 0,34, indicates that both have sufficient varies in size of chromosomes.

The calculation of the carrying capacity of urban settlements is intended to determine the availability and status of environmental aspects that are utilized by the community. This study aims to examine the availability of environmental support aspects in Jebres District, Surakarta City through the das sein and das sollen approaches. The results of this study indicate that the availability of settlements and supporting aspects in the Jebres District are still able to support the demand for housing in 2018 and projections until 2055. Analysis through the expectation approach (das sein) for 100% decent settlements and the quality of the supporting aspects capable has not been fully realized concretely (das sollen). The availability of green open space (RTH) in Jebres District also does not meet the standards set by the government (30%) where the total area of green open space in Jebres District is 23% of the total. The results of this study are related to the 3rd, 4th and 11th environmental principles. Keywords: carrying capacity, das sein-das sollen, environmental principles, green open space, settlements.

This research determines the Acceptable Level of Acceptance (ALA) based on the countries with active Nuclear Power Plant (NPP). The ALA is a particular value of public acceptance of NPP, indicating public support and participation in the program. If the public acceptance level is lower than the ALA, then the probability of public resistance against the program is relatively high and would harm the NPP. There is no correlation between the number of populations. This research uses four categories to classify public acceptance: (1) low, (2) moderate, (3) high, and (4) very high. Based on these categories, this research suggests that the moderate ALA is 27.5% of the acceptance level.

CoFe2O4, CoBi0.1Fe1.9O4, CoLa0.1Fe1.9O4, and CoAl0.1Fe1.9O4 nanoparticles were successfully synthesized by the coprecipitation method. After annealing at 700C for 5 h, the X-Ray Diffractometer results confirm that a single phase of cobalt ferrite-based nanoparticles is obtained, which is suitable for ICDD 22-1086. The addition of Bi3+, La3+ and Al3+ ions to the cobalt ferrite nanoparticles modified the crystallite size and lattice constant. Trivalent metal cation substitution tunes the crystallite size which has also been confirmed by measuring the grains with Scanning Electron Microscope images. In the Far Transform Infra-Red curve, the addition of metal ions (Bi3+, La3+, and Al3+) to cobalt ferrite nanoparticles resulted in absorption peaks at the tetrahedral and octahedral sites without any additional absorption peaks. The VSM results showed that saturation magnetization decreased drastically in the presence of trivalent non-magnetic cations, which confirms the replacement of Fe3+ by trivalent non-magnetic cations. The kOe order of the coercive field was obtained in this experiment. The largest coercive field of the cobalt ferrite nanoparticles was obtained with the addition of La3+ ions, i.e., 3.67 kOe suggest supporting both Jahn-Teller effect and strain-induced magnetism.

Direct Light Processing (DLP) is a 3D printer that uses resin in the product manufacturing process. The resin is formed through a curing process using UV light. The cast pattern is a replica of the object that will be made in the metal casting process. Cast patterns are usually made using wood or resin. In this paper, discussed the optimization of DLP 3D printing parameters for the cast pattern manufacturing process. The parameters discussed are thickness and exposure time. The data analyzed is the time of production and the accuracy of the dimensions of the resulting product. This method can be used to determine the optimum parameters that can be used to produce products with accurate dimensions and short production times. The results obtained are the thickness and exposure time parameters affect the production time significantly. Meanwhile, the accuracy of product dimensions does not have a significant effect.

Research on the analysis of the source mechanism of the mainshock and aftershock events of the May 27, 2006, Yogyakarta earthquake, which is thought to have originated from the Opak fault and analysis of receiver function data to model the subsurface velocity P of the Central Java subsurface, to obtain a geological form model of the Opak fault. This research aims to support the development of the Yogyakarta Aerothroppolis area in terms of disaster analysis. The data used in this study are remote Teleseismic receiver function data from the MERAMEX station installed in 2004, and data for the Bantul earthquake event and its aftershock event in 2006. The results obtained from the analysis are that the Yogyakarta area is shaped like a half-graben close to Yogyakarta International Airport. The fault that separates the western part of Yogyakarta is still not identified. Based on the results of the rupture process analysis of the source along the Opak fault plane, some zones have not yet released their energy. The distribution of aftershocks due to the mainshock on 27 May 2006 is spread around the Opak fault, which is heading North-South, and West-East, which is thought to have activated the minor fault to the east of the Opak fault. The opak fault rupture area can be analyzed to have a Low Anomaly velocity P value from the receiver function data and is the same as the aftershock event obtained.

BACKGROUND Factor VIII (FVIII) inhibitors in hemophilia A (HA) patients render FVIII replacement therapy ineffective. Although its development cause is unclear, it has been classified into therapeutic and genetic-related etiologies. Single nucleotide polymorphisms (SNPs) in several cytokine genes, including interleukin (IL)-2, could increase the risk of FVIII inhibitor development. This study aimed to evaluate the association between IL-2 (rs2069762) gene SNP and FVIII inhibitor development in Indonesian patients with severe HA. METHODS The IL-2 (rs2069762) gene SNP was examined in 119 HA patients. The presence of FVIII inhibitors was quantified using an enzyme-linked immunosorbent assay, with a titer of

Mycotoxin contamination in feed a common problem in broiler chickens. The present systematic review and meta-analysis examined the impact of mycotoxin and efficacy of various feed additives on production performance of broiler chickens fed mycotoxin-contaminated diets (MCD). A total of 28 studies comprising 45 mycotoxin-challenged experiments were selected following PRISMA guidelines. Feed additives included in the analyses were commercial mycotoxin binder (CMB), mycotoxin binder (MB), mannan-oligosaccharides (MOS), organic acid (OA), probiotics (PRO), protein supplementation (PROT), phytobiotics (PHY), additive mixture (MIX), and a combination of CMB + other feed additives (CMB+). Random effects model and a frequentist network meta-analysis (NMA) were performed to rank the efficacy of feed additives, reported as standardized means difference (SMD) at 95% confidence intervals (95% CI). Overall, broiler chickens fed MCD had significantly lower final BW (SMD = 198; 95% CI = 198 to 238) and higher FCR (SMD = 0.17; 95% CI = 0.13 to 0.21). Treatments with MB, MOS, PHY, and MIX improved BW of birds fed MCD (P < 0.05) but lower compared to CON (P < 0.05). The NMA demonstrated that the CMB + was the highest performing additive (P-score = 0.791) to remedy mycotoxicosis. The MOS, MB, and OA also showed high efficacy based. Adverse effects on organ weights were observed on the increase of liver and heart and the decrease of intestinal tract (P < 0.001). Altogether, several feed additives may help to ameliorate mycotoxicosis in broiler chickens although the efficacy was low pertaining to the severity of the mycotoxicosis.

The research problem is that West Nusa Tenggara lacks the local characteristics to support sustainable eco-tourism and culture. The case study of the quantitative descriptive method was used to describe the motivation behind the establishment of sustainable eco-tourism, the evaluation of triple helix support factors (government, academia, and green product business actors) in the development of the ecotourism, evaluation of internal factors of ecotourism, SWOT analysis, and the establishment of a green entrepreneur development strategy model in weaving and pearl industries. The results of the study show that the pearl shell breeding industry in West Lombok, which consists of pearl shellfish culture, treatment, pearl shell growing, pearl cultivation, pearl processing, pearl processing into jewelry, processing pearl shell waste into jewelry, and souvenirs, as well as the use of pearl shell meat for consumption, has high economic value and provides strong appeal for tourists. Pearl shell businesses from upstream to downstream can be used as a typical green tourism model of West Nusa Tenggara with high educational value. The woven fabric industry with natural dyes from various types of leaves, skins, and logs in Pringgasela village can empower 1,250,000 women.

In this study, hematite (α-Fe2O3) nanoparticles were synthesized using the sol-gel method. The physical properties are modified by the citric acid concentration used as a fuel. The XRD results showed that the obtained sample had a rhombohedral (hexagonal) structure with space group R3c. The crystallite size calculated using the Scherer formula at the strongest peak was found to be 32.14, 24.58, and 23.21 nm with an increase in citric acid molarity of 0.3, 0.4, and 0.5, respectively. The absorption band in the FTIR spectrum shows the characteristics of hematite nanoparticles. Finally, the confirmed magnetic properties of the VSM data revealed a significant decrease in the coercive field, that is, 935, 610, and 548 Oe, as the citric acid concentration increased by 0.3, 0.4, and 0.4, respectively.