Universidad de Palermo
  • Buenos Aires, Argentina
Recent publications
In Argentina, transgender women (TGW) have a high HIV prevalence (34%). However, this population shows lower levels of adherence, retention in HIV care and viral suppression than cisgender patients. The World Health Organization (WHO) recommends the transition to dolutegravir (DTG)-based regimens to reduce adverse events and improve adherence and retention. The purpose of this study was to determine retention, adherence and viral suppression in naïve TGW starting a DTG-based first-line antiretroviral treatment (ART) and to identify clinical and psychosocial factors associated with retention. We designed a prospective, open-label, single-arm trial among ART-naïve HIV positive TGW (Clinical Trial Number: NCT03033836). Participants were followed at weeks 4, 8, 12, 24, 36 and 48, in a trans-affirmative HIV care service that included peer navigators, between December, 2015 and May, 2019. Retention was defined as the proportion of TGW retained at week 48 and adherence was self-reported. Viral suppression at <50 copies/mL was evaluated using snapshot algorithm and as per protocol analysis. Of 75 TGW screened, 61 were enrolled. At baseline, median age was 28 y/o., HIV-1-RNA (pVL) 46,908 copies/mL and CD4+ T-cell count 383 cells/mm ³ . At week 48, 77% were retained and 72% had viral suppression (97% per protocol). The regimen was well tolerated and participants reported high adherence (about 95%). Eleven of the fourteen TGW who discontinued or were lost to follow-up had undetectable pVL at their last visit. Older age was associated with better retention. DTG-based treatment delivered by a trans-competent team in a trans-affirmative service was safe and well tolerated by TGW and associated with high retention, high adherence and high viral suppression at 48 weeks among those being retained.
To some extent, tourism education is facing an unparalleled crisis, probably a terminal crisis. Metrics applied in research and publications are wreaking havoc in the discipline as never before. Many professional researchers are pressed to publish leaving their classrooms to amateur professors. This chapter insights on the genesis and evolution of higher tourism education as well as the curricula formation. At a first glimpse, the indiscipline of tourism research -originally denounced by Tribe- is accompanied by other problems which include high dropout rates, a dissociation between professional research and learning without mentioning low salaries and bad working conditions once the Ba is earned. The present chapter interrogates the present problems of higher tourism education and the future of the discipline in an ever-changing and global world.
Doubtless, COVID-19 has affected not only the tourism industry as well as global trade but also education worldwide. Although technology occupied a central position in online classroom, no less true was that many students had not access to digital platform. This chapter interrogates on the problem of curricula in higher tourism education for Argentina to understand the new global risks. The pandemic has opened the doorsteps to new opportunities, problems and challenges educators should bear on mind. In this vein, creativity and entrepreneurship play a leading role in the formation of a new curricula in a post COVID-19 context. To think the future research lines of tourism and hospitality in a post-COVID-19 context is very hard to grasp, simply because the future of tourism seems to be a bit uncertain. In fact, in this post-COVID-19 world, new technologies lead us to a landscape without tourists. At the same time, digital technology helps in the creation of more resilient and smarter destinations.
This study examined associations between receiving and giving support, and their imbalance on depression symptoms in adolescents. Our sample included 2,111 young adolescents drawn from 6th Wave European Social Survey who completed measures of social support and the Centre for Epidemiologic Studies-Depression (CES-D). A hierarchical linear regression demonstrated that both receiving and giving social support were associated with a 51% and 34% reduced risk of being depressed, respectively. However, analysis of group differences indicated those high on both giving/receiving, that is, a positive balance, reported less depression, compared to those with a negative balance, that is, low on both, with the highest symptoms observed by those reporting a negative imbalance, that is, high giving and low receiving social support. While there are benefits to receiving and giving social support, there is also a cost when this is imbalanced. Our findings are discussed from an equity theory and lifespan perspective.
Objectives Patients with dementia show dissociations between musical semantic memory (i.e., spared musical lexicon) and other memory modalities, except in some severe cases. We aim to study, from a neuropsychological point of view, the dissociation between musical semantic memory compared to language and verbal memory in a patient with severe Behavioral Variant Frontotemporal Dementia (bvFTD). We hypothesize a single dissociation between these domains will be found, with sparing of musical semantic memory. Methods LC, a patient with severe bvFTD, and three matched controls were assessed through language, semantic, and episodic memory, and musical semantic memory tasks. The control group had similar music taste as LC: to participate as controls, tango must be one of their favorite musical genres. Results LC showed impairment in all Verbal Memory tasks, but not in musical tasks. There was a dissociation between musical semantic memory, and language and verbal semantic memory. Conclusions The musical lexicon can be preserved in advanced stages of dementia, which supports the idea that music can be a therapeutic tool in patients with severe dementia.
In the Big Data era, sampling remains a central theme. This paper investigates the characteristics of inverse sampling on two different datasets (real and simulated) to determine when big data become too small for inverse sampling to be used and to examine the impact of the sampling rate of the subsamples. We find that the method, using the appropriate subsample size for both the mean and proportion parameters, performs well with a smaller dataset than big data through the simulation study and real-data application. Different settings related to the selection bias severity are considered during the simulation study and real application.
The COVID-19 pandemic, places children in a situation of vulnerability, as a result of the restrictions placed on their ability to move outside the home in limited social interactions. This chapter comments on children’s opinions and analyses their daily experiences during the period of compulsory social isolation, and the effects on their lives and well-being. The study was carried out with 21 boys and girls aged 8–12 years living in a city placed in the Province of Buenos Aires, Argentina, a country in the Southern Cone. A questionnaire created on Google form was used, consisting of open-ended questions about the coronavirus and covering different dimensions of children’s daily life: the fears they feel in the face of the pandemic, the changes in their personal relationships with members of their cohabiting family group and members of their extended family and friends, their well-being, the activities they can and cannot carry out, the decisions adults have made for children and the decisions made at the government level. Children commented on the activities they do during the quarantine period as they have to stay at home with their families. In addition, they described the activities they are unable to do and those that they would like to do again, as well as who they would like to see. They also reported on how they feel about not being able to leave their homes and whether they feel safe being at home without going out. Finally, they were consulted about what adults should have thought, especially about children during the COVID-19 pandemic and the measures or decisions that should have been taken in the face of the pandemic both at the family, organisational and government level.KeywordsChildrenCOVID-19Daily lifeConfinement stagePublic policy
Orientations toward interpersonal arguing were systematically assessed in Argentina in this article. Several hundred university-connected respondents self-reported their motivations, understandings, and emotional reactions for face-to-face arguing. Comparisons were made to earlier investigations in Mexico and Chile. We found that Argentinian, Mexican, and Chilean orientations were identifiably different. Argentinian men and women often had different orientations, as was also the case in Mexico and Chile (but not in all other nations studied in this global project). Older Argentinian respondents were less aggressive and less interested in arguing than younger ones. Arguing motivations generally reproduced the U.S. correlational patterns, which was not as clearly the case in Mexico and Chile. Early reports on the connections between the standard orientation variables and both power distance and workplace arguing are also reported, and show points of interest.
The adsorption properties of phenytoin (PHT) on B12N12, AlB11N12, and GaB11N12 nanoclusters were theoretically investigated to find a suitable sensor. All calculations were performed using the B3LYP-D density functional theory in the gas and solution phases. The absorption energy was -22.45, -55.67, and -53.33 kcal mol⁻¹ for B12N12, AlB11N12, and GaB11N12 in their most stable configurations, respectively. After PHT adsorption on nanoclusters, their electrical conductivity changes occurred -28.19%, 7.73%, and 27.19 % for the B12N12, AlB11N12, and GaB11N12, respectively. Thus, it is clear that the B12N12 and GaB11N12 nanoclusters indicated a considerable change in electrical conductivity. On the other hand, the recovery time calculation based on transition theory confirmed that only the pristine B12N12 showed a short recovery time of 0.03 s, demonstrating that PHT adsorption on that is reversible and more favorable. The solution phase calculations showed that interacted complexes are stable in water and more sensitive and reactive toward the PHT molecule in the water phase. The UV-vis spectroscopy result revealed that the PHT/B12N12 complex exhibits a shift to higher wavelength (lower energies) regions. Therefore, it is concluded that the B12N12 nanocluster can be used as a suitable detector of phenytoin.
Background Evidence among key populations supports acceptability of HIV self-testing (HIVST) due to its privacy and convenience. However, insufficient research has been done among transgender women (TGW), especially in Latin America. Consequently, the aim of this study was to explore the acceptability, perceptions and recommendations for HIVST implementation among TGW in Buenos Aires. Methods A focus group was conducted in July 2019. Particpants were invited to touch and learn about a displayed HIVST kit. The following main topics were explored: acceptability, reasons for seeking self-testing, preferences for training, distribution, periodicity and recommendations for HIVST implementation. Results The sample consisted of 12 TGWs; mean age of 26 years (IQR = 22–28); 66% had history of sex-work. The main motivations for seeking HIVST were convenience, privacy, and usage to reduce stigma and discrimination by health-care providers. Recommendations for HIVST were: distribution from primary health centers and trans-sensitive centers; affordable price; assistance by peer health promoters; and the provision of clear written and video instructions. Conclusions Tailored implementation of HIVST can increase HIV testing rates, early detection, and linkage to HIV-care in this high-prevalence group. This study provided community-driven suggestions to inform and adapt an HIVST feasibility pilot study and future implementation in Argentina.
At the end of December of 2019, the world stopped because of a new virus outbreak originally reported in Wuhan, China. This virus was rapidly disseminated to the four continents situating as one of the worst pandemics the world faced in its history. Governments desperately urged for the adoption of radical measures that finely affected not only global commerce but the tourism industry. The WHO (World Health Organization) strongly recommended some restrictive measures such as quarantines or lockdowns to ban the public circulation, as well as social distancing and the closure of borders and the airspaces. All these measures led countries to the brink of an economic collapse. Economies that are dependent on tourism were more affected than others that keep alternative forms of production. The global world, as we know it, set the pace to a feudalized (if not fractured) world where each country closed their borders to “Other.” The present chapter interrogates what we dubbed as the “decline of hospitality,” a trend that originated just after 9/11. To some extent, the COVID-19 pandemic is not news, while it affirms the effects of the War on Terror. Far from being a foundational event, COVID-19 engages with the previous backdrop initiated just after 9/11. Now the War on Terror sets the pace of a war against a virus. This chapter describes the radical political shifts that happened in Argentina along with the pandemic while laying the foundations towards a new understanding of travel behavior.KeywordsMobilitiesTourismTourist gazeWicked gazeArgentina
We investigate the impact of the Bank of England's asset purchase program (APP) on the composition of assets of UK banks with unique data on the received reserves injections. Compared to the control group, receiving banks reallocated their assets towards lower risk-weighted investments, such as government securities, but did not supply more credit to the real economy. Overall, our findings suggest that risk-based capital constraints can limit the effectiveness of expansionary unconventional monetary policies and provide incentives for carry trade activities when banks are not adequately capitalised.
Reseña del libro: Dorothée Baumann-Pauly y Justine Nolan (eds.), Business and Human Rights: From Principles to Practice, New York, Routledge, 2019. Dorothée Baumann-Pauly y Justine Nolan, son las editoras de una obra colectiva pensada para todos aquellos que creemos en la implementación efectiva de los Principios Rectores sobre Empresas y Derechos Humanos de la ONU. En el libro, se enfatiza el rol de las empresas y su labor conjunta con los estados para avanzar en el campo del derecho internacional de los derechos humanos, que traerá como resultado múltiples beneficios para los actores involucrados.
This study aimed to evaluate the feasibility of using more dolomite aggregates in asphalt surface mixtures that are typically used by West Virginia Division of Highways (WVDOH). The laboratory test results indicated that increasing dolomite content in asphalt surface mixtures resulted in a faster deterioration rate at the early polishing stage. In addition, asphalt surface mixtures containing more than 50% dolomite coarse aggregates would significantly reduce roadway safety. The field test results validated that dolomite shall not exceed 50% of coarse aggregate in asphalt surface mixture if the projected traffic volume is greater than 3.0 million equivalent single axle loads (ESALs).
Background The rapid increase in demand for health services as a result of the COVID-19 outbreak has created significant challenges for health systems. National and international health authorities have declared reproductive health services as essential, particularly those related to prevention, care during pregnancy, delivery and postpartum, as well as abortion services. This research was conducted by a regional team in cooperation with nine local organizations that are members of the Latin American Consortium against Unsafe Abortion ( Consorcio Latinoamericano Contra el Aborto Inseguro , CLACAI). Objectives Our research aimed to examine the provision of reproductive healthcare services, with a focus on abortion, in nine countries during the first few months of the pandemic (March to September 2020). Methods Our research design developed a set of quantitative and qualitative indicators to monitor the availability and accessibility of abortion services during the COVID-19 pandemic. Researchers collected the quantitative data by reviewing regulations and other documents, government and civil society reports, and official statistics; the qualitative data was acquired through interviews with key actors, and non-representative surveys completed by healthcare professional and end users of reproductive services. Results Although six of the nine countries we researched deemed reproductive health services essential, only two of these six countries considered abortion services to be essential, and all nine countries reported difficulties in accessing abortion services. Restrictive abortion laws remained in place in the majority of countries (seven), and as a result access to abortion services became even more limited than it had been before the pandemic. At the same time, good practices to facilitate access to abortion services in healthcare facilities, updated regulatory frameworks, and collaboration between civil society and government agencies were identified and should continue to be promoted even after the pandemic crisis has subsided. Conclusions The pandemic catalyzed what was already happening in each country, and as such abortion services have become more accessible in countries like Argentina, where the so-called green wave has been generating social, legal and policy changes, whereas in countries such as Ecuador, where abortion is legally restricted and opposed to by the government, access to safe abortion became even more difficult than it was before the pandemic. However, the general trend has been a lack of adequate adaptation in order to guarantee quality in abortion care. That said, there have also been some interesting and positive service provision initiatives, such as telemedicine, implemented in at least two countries, which, if maintained long-term, could improve access to safe abortion.
Aims This study, part of a project on a Decision Support System (DSS) on coeliac disease (CD), aimed at assessing the usefulness of a minimally invasive, cheap Point-of-Care Test (POCT) in a population of school children, who underwent the largest CD screening program done to date. Methods Ethics approval was granted to screen up to 20000 children between 3 and 13 years of age. An information leaflet was handed to the subjects through their respective schools. This also contained a questionnaire and consent form. The chosen POCT was able to detect anti-tissue transglutaminase antibodies IgM, IgA and IgG. Anonymized information was inserted into a computer database, by means of a user-friendly interface. The information retained included the answers of the questionnaire and POCT results. The children who were found to have a positive POCT, as well as the children who had at least 5 symptoms, were recalled and offered further testing. POCT was validated, according to 2012 ESPGHAN guidelines, against reference results of histology or against another anti-TG2 antibody test with performance similar to anti-endomysial antibodies. Diagnostic accuracy and post-test probability were calculated using the all-purpose 4-fold Table Analyzer and the interactive nomogram for post-test probability offered by the page of the Center for Evidence Based Medicine (http://cebmjr2.ox.ac.uk/). Results By screening 19,923 children, we found 137 POCT ‘positive’ cases. Out of 134 children who accepted and completed further investigations, 123 were positive at anti-TG2 antibody test and 11 negative. Final diagnosis of CD was made in 105 subjects. Eighty-three fulfilled the serological diagnostic criteria according to the new ESPGHAN guidelines 2020 and 56% of the diagnosed children had no symptoAmong 19584 children with POCT negative, 374 had 5 or more symptoms and 166 accepted further investigations: 2 resulted tTG positive and 4 borderline (< 2 times the upper limit of normal). In one case, CD was confirmed and investigations are pending in the other five. In the whole population, POCT sensitivity, specificity, positive and negative predictive values were 98% (96%CI, 95-100), 94% (95%CI, 90-97), 92% (95%CI, 87-96) and 99% (95%CI, 97-100), respectively. Likelihood ratio + was 15.3 (95%CI, 8.6-27.1). Considering a pre-test probability of CD 1% in the general paediatric population regardless of symptoms and 42% (95%CI, 37-48) such as that found in our population also with 5 or more symptoms, post-test probability was 13% and 92%, respectively. Conclusion As CD is largely under diagnosed, POCT, with its high negative predictive value may be a valuable tool for mass screening. It may also be valuable at the pediatrician’s office whereby in the presence of symptoms, a positive POCT result should prompt further testing.
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605 members
María Lolich
  • Departamento de Neurociencias y Neuropsicología Clínica
Maximiliano E. Korstanje
  • Ciencias Económicas
Veronika Diaz Abrahan
  • Departamento de Humanidades y Ciencias Sociales
Denise Benatuil
  • Departamento de Psicología
Andrés Buschiazzo
  • Departamento de Psicología
Av. Córdoba 3501, Buenos Aires, Argentina