Universidad Regional Amazónica IKIAM

Antibiotics are essential chemicals for medicine and agritech. However, all antibiotics are small molecules that pathogens evolve antimicrobial resistance (AMR). Alternatively, antimicrobial peptides (AMPs) offer potential to overcome or evade AMR. AMPs provide broad-spectrum activity, favourable biosafety profiles, and a rapid and efficient mechanism of action with low resistance incidence. These properties have driven innovative applications, positioning AMPs as promising contributors to advancements in various industrial sectors. This review evaluates the multifaceted nature of AMPs and their biotechnological applications in underexplored sectors. In the food industry, the application of AMPs helps to suppress the growth of microorganisms, thereby decreasing foodborne illnesses, minimizing food waste, and prolonging the shelf life of products. In animal husbandry and aquaculture, incorporating AMPs into the diet reduces the load of pathogenic microorganisms and enhances growth performance and survival rates. In agriculture, AMPs provide an alternative to decrease the use of chemical pesticides and antibiotics. We also review current methods for obtaining AMPs, including chemical synthesis, recombinant DNA technology, cell-free protein synthesis, and molecular farming, are also reviewed. Finally, we look to the peptide market to assess its status, progress, and transition from the discovery stage to benefits for society and high-quality products. Overall, our review exemplifies the other side of the coin of AMPs and how these molecules provide similar benefits to conventional antibiotics and pesticides in the agritech sector.

One of the paramount challenges confronting the global population today is acknowledging humanity’s dependence on natural capital for a vast array of benefits crucial to our health, sustenance, and overall well-being (Díaz et al., 2015; Perschke et al., 2023). It is crucial for society to expand its comprehension of natural capital beyond merely associating it with the benefits provided by natural resources, or limiting it to environmental protection and sustainability, such as absorbing waste and pollution, or viewing it solely as the primary driver of economies (Jo et al., 2021). Thus, it must embrace the comprehensive and diverse aspects of natural capital, which include essential goods and services such as clean air, carbon sequestration, food production, pollination, and clean water. These rely directly and indirectly on biodiversity across its genetic, species, and ecosystem levels. In other words, achieving this broad spectrum of benefits in the “natural capital equation” necessitates the consideration of relationship or link between biodiversity and ecosystem services (Díaz et al. 2006, 2015). Moreover, biodiversity itself depends critically on forest ecosystems, which play a pivotal role in maintaining the balance between nature and human societies (with an estimated 80% of global biodiversity concentrated in forests) (FAO, 1993).

Socioscientific issues are a key aspect of science education, enhancing citizens’ understanding of the intricate relationships among global concerns and fostering their engagement in informed decision making on these problems. To this end, teachers must be able to establish connections between scientific content, its application in everyday life, and its impact on social, economic, and environmental dimensions. This study analyzes the factors that influence teachers’ ability to address these topics in the classroom. It includes two studies. The first study (n = 213) examines prospective science teachers’ interest in and perceived knowledge of 14 issues related to the Sustainable Development Goals (SDGs). The second study (n = 135) analyzes the types of arguments that participants use to justify their interest. A mixed-method ex post facto design was employed, using ad hoc questionnaires. The results suggest significant differences between interest and perceived knowledge across certain specific topics. Additionally, the topic addressed tends to evoke specific dimensions within arguments, with cultural/social and ecological/environmental aspects being the most prevalent, influencing the connections teachers establish with everyday life contexts. These findings highlight how interest, perceived knowledge, and the topic itself influence the dimensions considered in argument construction when discussing socioscientific issues and may contribute to the development of teacher training programs that foster a deeper understanding of the complex nature of these sustainability-related issues.

Antioxidants are essential compounds with diverse applications, and medicinal plants are a natural source of these biomolecules. Philodendron heleniae, a species native to the Ecuadorian Amazon, belongs to a genus renowned for its traditional therapeutic uses. Extracts from the stems and roots of several Philodendron species have been widely used to treat stress, bladder disorders, and snakebite wounds, underscoring their medicinal potential. This study investigates the volatile composition, antioxidant properties, and molecular docking of ethanolic extracts from P. heleniae, aiming to expand its applications. Phytochemical analysis revealed a rich profile of tannins, phenolic compounds, flavonoids, and terpenoids. Antioxidant assays (ABTS and DPPH) demonstrated the extract’s strong free radical scavenging capacity, comparable to the standard Trolox. GC-MS analysis identified 48 volatile and semi-volatile metabolites, predominantly phenolic compounds, terpenoids, and lipid-like molecules. Fractionation of the crude ethanolic extract into aqueous and ethanolic fractions simplifies the downstream analytical steps and facilitates the identification and the evaluation of the higher abundance of antioxidant-related metabolites. Molecular docking supported these findings, highlighting strong binding affinities of stigmasterol and desmosterol to catalase, an enzyme critical for reducing oxidative stress. These results position P. heleniae as a promising source of natural antioxidants with potential pharmaceutical applications, while emphasizing the importance of conserving Ecuador’s biodiversity and its bioactive resources.

Rose cultivation is an economic cornerstone in the Andean region of Ecuador. Due to its economic significance, ongoing genetic improvement of roses is crucial for maintaining competitiveness. However, publicly available studies that use models to predict the performance of varieties in breeding programs are scarce in the Andean region, possibly due to the challenges of implementing accurate phenotyping in a practical framework. Therefore, our study aimed to estimate heritability and predict the performance of Ecuadorian rose varieties using best linear unbiased prediction (BLUP), utilizing a phenotypic database from the company Conectiflor. The analysis included 33 unique rose varieties from nine distinct pedigrees. We assessed traits such as head size, petal count, stem length, and color, finding the highest heritability for stem length. Model diagnostics indicated that the model may not be well-suited for predicting color. Based on BLUP values, we recommend several varieties for use in breeding programs. Additionally, we propose a BBCH-based phenotyping protocol, developed in collaboration with workers at Conectiflor, for large-scale breeding settings. This study presents previously undisclosed data on rose breeding programs and provides valuable insights that can inform future breeding strategies and improve the selection of superior varieties.

The study evaluates the implementation of check dams as nature-based solutions to address soil erosion, improve sediment quality, and enhance water retention in the Urku Huayku ravine, located on the Ilaló volcano in Ecuador. Weekly water and sediment samples were analysed from 2021 to 2023. Critical parameters measured include pH, electrical conductivity, nutrient concentrations, and organic matter content. Macroinvertebrates were collected to assess biodiversity changes using the Andean Biotic Index (ABI) and the Shannon Diversity Index. Results show significant improvements: water quality remained neutral (average pH 7.06), while sediment organic matter increased from 0.2% in 2021 to 3.2% in 2023. Additionally, biodiversity improved, with a 355.6% increase in macroinvertebrate abundance. Statistical tests confirmed the positive impact of check dams on sediment and water quality. The study also identified potential areas for additional check dam installations using QGIS analysis, emphasising steep slopes as ideal locations. This study demonstrates the efficacy of check dams in the restoration of degraded ecosystems and underscores their pivotal role in climate change mitigation. Through the enhanced storage of sediment organic matter, check dams facilitated the capture of approximately 58% of carbon. Additionally, they contributed to improved biodiversity. Further research is recommended to optimise dam placement and explore additional biodiversity indicators in Andes Mountain water bodies over 3000 m above sea level.

Plants cope with the environment by displaying large phenotypic variation. Two spectra of global plant form and function have been identified: a size spectrum from small to tall species with increasing stem tissue density, leaf size, and seed mass; a leaf economics spectrum reflecting slow to fast returns on investments in leaf nutrients and carbon. When species assemble to communities it is assumed that these spectra are filtered by the environment to produce community level functional composition. It is unknown what are the main drivers for community functional composition in a large area such as Amazonia. We use 13 functional traits, including wood density, seed mass, leaf characteristics, breeding system, nectar production, fruit type, and root characteristics of 812 tree genera (5211 species), and find that they describe two main axes found at the global scale. At community level, the first axis captures not only the ‘fast-slow spectrum’, but also most size-related traits. Climate and disturbance explain a minor part of this variance compared to soil fertility. Forests on poor soils differ largely in terms of trait values from those on rich soils. Trait composition and soil fertility exert a strong influence on forest functioning: biomass and relative biomass production.

UNESCO Global Geoparks play a crucial role in promoting the Sustainable Development Goals (SDGs) through research, geoeducation, and geotourism. In the case of the Napo Sumaco Aspiring UNESCO Global Geopark, this is being implemented through the collaborative and organized work of the local community, combining bottom-up actions with top-down strategies. The aim is to demonstrate that the efforts of geopark collaborators can lead to the establishment of a geopark and contribute to the sustainability of communities. To board sustainability, it is proposed to evaluate the following actions: a comprehensive analysis based on human potential and the economic valuation of their time in geopark construction, organizational strategies, and management actions in line with the SDGs. The results of this study highlight the crucial role of community social capital in promoting actions for territorial and community sustainability, promoting beneficial and sustainable tourism, and protecting natural and cultural heritage. The various actions are closely linked to 82% of the SDGs, promoting knowledge exchange, community organization, sustainable use of natural resources, appreciation of human capital, and ancestral knowledge of the Ecuadorian Amazon. It is concluded that the economic valuation of the time contributed by collaborators is essential to propose new models of management and construction of global geoparks, which recognize and properly value bottom-up actions by implementing ancestral communitarian activities as Minka (community-based organizational processes) and Turkana (exchange-barter-reciprocity).

The agri-food supply chain (AFSC) is vital to ensure global food security. It faces significant environmental and economic challenges, requiring the adoption of circular economy (CE) principles to enhance sustainability and resource efficiency. This article presents a bibliometric analysis of 162 Web of Science (WoS) and Scopus documents from 2017 to 2024, focusing on contributions from leading authors and countries regarding CE application in AFSCs. Using bibliometrix R-Tool Version 4.3.2 and VOSviewer 1.6.20, we identified key topics, such as “Transforming Agriculture through Innovation and Sustainability in the Supply Chain” and “Implementation of a Circular Economy Framework in Agricultural Supply Chains”. We also pinpointed outdated and oversaturated research topics while proposing emerging subjects based on multiple analyses of the scientific literature corpus (title, abstract, and keywords). Finally, the combined bibliometric, network, and content analysis provided a comprehensive “big picture” of CE application in the AFSC, guiding future projects and research.

CRISPR/Cas9 has emerged as the predominant method for genome editing due to its cost-effectiveness and broad applicability, playing a crucial role in advancing sustainable practices across various sectors. This systematic review employs the PRISMA methodology to evaluate the impact of CRISPR/Cas9 on environmental protection and on achieving Sustainable Development Goals (SDGs) such as SDG 2, 3, 6, 7, 9, 12, 13, and SDG15. These goals focus on the responsible use of natural resources, reducing the negative effects of climate change and ensuring safe food for the entire population. Analyzing data from the Web of Science, the review found significant growth in related publications, with a 30% increase since 2014, predominantly from the US, China, Germany, and the UK. The study categorizes the scientific developments into these trends, the enhancement of plant tolerance to environmental stresses, as evidenced by the consistent focus on terms such as “tolerance” and “plant” since 2021. Furthermore, the relevance of “Gene Editing” has increased significantly since 2022, underscoring the importance of CRISPR/Cas9 in developing resilient crops that can withstand extreme conditions. These trends underscore the growing significance of biotechnological advancements in the mitigation of climate change’s effects and the improvement of ecosystem stability. Key discussions include CRISPR/Cas9’s role in the development of fourth-generation biofuels and environmental biosensors, as well as its applications in enhancing genetic resilience and controlling invasive species. These innovations highlight CRISPR/Cas9’s potential in promoting sustainable resource management and energy generation, making a significant contribution to ecological conservation and sustainability efforts.

Worldwide, concrete is used as the material of choice in the construction sector. In Latin American countries, concrete is primarily used in structural elements, because it is a low-maintenance, versatile, and economical material. With its characteristics, concrete has made it possible to cover Ecuador’ housing deficit to some extent. However, this construction material does not entirely respond to the needs of local communities, who are especially concerned about the displacement of traditional techniques and the loss of cultural heritage. In Ecuador, different fiber- and earth-based materials have been used in the construction sector for a long time. These materials present different technical, environmental, social, and cultural characteristics. This study aimed to evaluate the sustainability of the production of six local materials in Ecuador under three dimensions: environmental, social, and cultural, using local data. The data were collected in local production workshops, and life-cycle-based methodologies were applied. The results showed the relevance of developing regional inventories to represent the reality of production within the territory. Additionally, integrating the evaluation of environmental, social, and cultural dimensions shed light on the current situation of the building materials production sector, identifying possible trade-offs or synergies with a sustainable and interdisciplinary approach.

Introduction Cervical Cancer (CC) is a preventable and treatable disease if detected early, yet it remains a global health challenge. In Ecuador, CC is the second most common cancer; however, screening uptake remains suboptimal due to poor knowledge, low willingness, and limited access to healthcare. Traditionally, CC screening requires a healthcare professional, creating social and access barriers. Innovative techniques such as “self-sampling” (SS) for human papillomavirus (HPV) detection offer a promising alternative. Objective This study evaluates the acceptability, attitudes, and user experience of a community-based SS program among a hard-to-reach population following a local educational session. Methods A quasi-experimental study was conducted in a rural community in Cuenca, Ecuador. Educational sessions were organized, after which women were offered the option to perform SS for HPV detection. Three questionnaires were administered to assess population characteristics, risk factors, and experiences toward the process. Results Of the 130 participants, 90% accepted SS, and 10% rejected SS. A significant number of women reported that SS was faster and less painful compared to traditional Papanicolaou tests (P < .05). Conclusions SS shows strong potential for increasing CC screening, especially in hard-to-reach areas, emphasizing the need to adapt screening programs to meet diverse community needs.

Deforestation caused by gold mining in the Ecuadorian Amazon has increased by 300% in the last decade, leading to severe environmental degradation of water and land resources. Effective remediation and revegetation technologies are still needed to address this issue. This study aimed to foster revegetation on 0.5 hectares of degraded land in Naranjalito, a mining site in the Ecuadorian Amazon, by applying plant-based biocompost and biochar and planting Ochroma pyramidale and Arachis pintoi, two pioneer species. The project’s objective was to evaluate the impact of these treatments on vegetation cover recovery through physicochemical and microbiological improvements in the soil. Four blocks and sixteen experimental plots were established: eight plots received treatments with varying doses of biocompost+biol (BIOC), four plots included plantations without biocompost (Not-BIOC), and four served as control plots (bare land). Over six months, dasometric characteristics of O. pyramidale and the expansion of A. pintoi were recorded. The data were analyzed using multivariate methods. The results revealed significant differences between treatments, with BIOC plots T4 and T1 showing greater improvements in vegetation development compared to Not-BIOC plots T3 and T2, confirming the positive influence of biocompost+biol. The BIOC treatment favored not only the planted species but also the secondary successional plant communities including certain grasses, leguminous plants, and other shrub and tree species, thus accelerating the revegetation process. This study demonstrates that biocompost application is an effective strategy to enhance plant recolonization on land severely degraded by gold mining in the Ecuadorian Amazon.

Understanding how the traits of lineages are related to diversification is key for elucidating the origin of variation in species richness. Here, we test whether traits are related to species richness among lineages of trees from all major biogeographical settings of the lowland wet tropics. We explore whether variation in mortality rate, breeding system and maximum diameter are related to species richness, either directly or via associations with range size, among 463 genera that contain wet tropical forest trees. For Amazonian genera, we also explore whether traits are related to species richness via variation among genera in mean species-level range size. Lineages with higher mortality rates—faster life-history strategies—have larger ranges in all biogeographic settings and have higher mean species-level range sizes in Amazonia. These lineages also have smaller maximum diameters and, in the Americas, contain dioecious species. In turn, lineages with greater overall range size have higher species richness. Our results show that fast life-history strategies influence species richness in all biogeographic settings because lineages with these ecological strategies have greater range sizes. These links suggest that dispersal has been a key process in the evolution of the tropical forest flora.

Neotropical regions near the equator are recognized as speciation “hot spots” reflecting their abundant biodiversity. In western South America, the coasts of Panama, Colombia, Ecuador, the Galápagos Archipelago, and northern Peru form the Tropical Eastern Pacific biome. This area has the greatest heterogeneity of sympatric fiddler crab species of any portion of the planet. Since the coastal fauna has not been assessed for almost 50 years, we studied fiddler crab species diversity in Ecuador and on the Galápagos Archipelago. Preserved collecting records for various species were examined at the U.S. National Museum of Natural History, Washington, DC, the American Museum of Natural History, New York, and the Naturalis Biodiversity Center, Leiden, the Netherlands. During a field study, 51 locations were collected resulting in over 870 preserved specimens (120 lots) along the 2237‐km (1390 mi) coast of Ecuador and on three Galápagos Islands. A neighbor‐joining tree was constructed using the Kimura 2‐parameter model with a partial DNA sequence of the cytochrome oxidase‐subunit 1 gene (COI) for a barcoding study. Twenty‐five taxa were collected during the surveys, while two more were noted from the literature and museum collections. Five published species are new to Ecuador. The species assemblage was divided among four genera: Uca, Leptuca, Minuca, and Petruca. Morphological definitions and photographic images are given for 27 species. COI sequences were obtained for 27 operational taxonomic units from Ecuador, with three morphologically indistinguishable cryptic or pseudocryptic taxa also revealed. Based on species distributions, it appears that the area between Cabo San Lorenzo and Punta Santa Elena serves as a weak barrier separating some “northern” from “southern” taxa. Since coastal Ecuador is undergoing rapid economic development, the construction of maricultural facilities and the deforestation of mangroves promote wholesale habitat destruction. As habitat diversity is reduced, it is expected that there will be, in general, a local decline in fiddler crab species diversity with some taxa becoming rare or extinct.

The Satisfaction With Life Scale (SWLS) is a widely used self-report measure of subjective well-being, but studies of its measurement invariance across a large number of nations remain limited. Here, we utilised the Body Image in Nature (BINS) dataset–with data collected between 2020 and 2022 –to assess measurement invariance of the SWLS across 65 nations, 40 languages, gender identities, and age groups (N = 56,968). All participants completed the SWLS under largely uniform conditions. Multi-group confirmatory factor analysis indicated that configural and metric invariance was upheld across all nations, languages, gender identities, and age groups, suggesting that the unidimensional SWLS model has universal applicability. Full scalar invariance was achieved across gender identities and age groups. Based on alignment optimisation methods, partial scalar invariance was achieved across all but three national groups and across all languages represented in the BINS. There were large differences in latent SWLS means across nations and languages, but negligible-to-small differences across gender identities and age groups. Across nations, greater life satisfaction was significantly associated with greater financial security and being in a committed relationship or married. The results of this study suggest that the SWLS largely assesses a common unidimensional construct of life satisfaction irrespective of respondent characteristics (i.e., national group, gender identities, and age group) or survey presentation (i.e., survey language). This has important implications for the assessment of life satisfaction across nations and provides information that will be useful for practitioners aiming to promote subjective well-being internationally.

Karst aquifers are highly vulnerable to contamination due to their unique hydrogeological characteristics and increasing anthropogenic pressures. Given the challenges and costs associated with remediation, this study evaluates the groundwater vulnerability of karst formations in the Western Amazon Basin using three assessment methods: EPIK, DRASTIC, and DRASTIC-LUC. Geospatial data and sensitivity analysis were employed to assess the Napo Karst Formation. The results show that DRASTIC and EPIK classified 45.76% and 35.38% of the area as highly vulnerable, while DRASTIC-LUC classified 57.47% as moderately vulnerable. Sensitivity analysis identified depth to the water table and infiltration conditions as the most critical factors influencing vulnerability. The moderate-to-high vulnerability observed raises concerns about the risks to both surface and groundwater resources, which local populations heavily depend on. This study provides a valuable baseline for future research and offers essential guidance for decision-makers to mitigate activities that could degrade water quality in the Western Amazon Basin.