Universidad Católica San Antonio de Murcia

Accelerometers are tools specifically engineered for quantifying differences in force or acceleration over time, providing data regarding the magnitudes and frequency of movement. It could be utilized in the flamenco dance study field for monitoring the movement to reduce the risks of injuries or pain, as well as to give recommendations for making a reasonable and scientific training plan for dancers to improve their technique. The aim of this study is to introduce how to monitor flamenco dance movement with accelerometers, and suggestions for future studies. This study makes a detailed introduction from the following aspects: accelerometer selection, monitor use protocols, and data process and analysis.

The present randomized study investigated the effect of acute supplementation of 800 mg/kg of ketone monoester ingestion (KE) or placebo (PL) and 210 mg/kg of NaHCO 3 co-ingestion on cycling performance of WorldTour cyclists during a road cycling stage simulation. Twenty-eight cyclists participated in the study (27.46 ± 4.32 years; 1.80 ± 0.06 m; 69.74 ± 6.36 kg). Performance, physiological, biochemical, and metabolism outcomes, gut discomfort, and effort perceived were assessed during a road cycling simulation composed of an 8-min time-trial (TT) performance + 30-s TT + 4.5 hr of outdoor cycling + a second 8-min TT + a second 30-s TT. Greater absolute and relative mean power during the first 8-min TT ( F = 5.067, p = .033, , F = 5.339, p = .029, , respectively) was observed after KE than after PL (KE: 389 ± 34, PL: 378 ± 44 W, p = .002, d = 0.294 and KE: 5.60 ± 0.42, PL: 5.41 ± 0.44 W/kg, p = .001, d = 0.442). Additionally, greater concentration of β-hydroxybutyrate blood concentration ( F = 42.195, p < .001, ) was observed after KE than after PL during the first steps of the stage (e.g., after warm-up KE: 1.223 ± 0.642, PL: 0.044 ± 0.058 mM, p < .001, d = 2.589), although the concentrations returned to near baseline after 4.5 hr of outdoor cycling. Moreover, higher values of anion gap were observed ( F = 2.333, p = .026, ) after KE than after PL ingestion, after the warm-up and after the first 8-min and 30-s TT. Additionally, lower concentrations of were reported in the KE condition after warm-up and after the first 8-min and 30-s TT. During the initial phase of the stage simulation, acute supplementation with KE + NaHCO 3 co-ingestion enhanced 8-min TT cycling performance (3.1%) in WorldTour cyclists with a concomitant hyperketonaemia.

The COVID-19 pandemic in 2020, has accelerated technological immersion into society, economy and public administrations. The sports organisations are no strangers to this digitisation and must carry out their own digital transformation. However, investment in digital technology must be preceded by a diagnosis of the technological needs of each sports entity. Said mapping will help organisations know the most appropriate technological tools for their core businesses so they can properly design their digital transformation strategies. The objectives of this study were to design and create a tool to understand the digital structure of Spanish sports. The result has been the configuration of an instrument that includes the description of different technologies and different digital competencies specific to the sports industry, and which allows individuals to know the use, importance, perceived difficulty of use and economic accessibility of available technologies, as well as the degree of developed competency in the different sports organisations. It is concluded that the creation and application of a consultation instrument on digitalisation is the first and necessary step to carry out relevant, in-depth, valid and replicable research, which allows information to be gathered on the digitalisation needs of sports organisations to design their digital transformation roadmap and that the aids for digital transformation is distributed efficiently.

We aimed to investigate the initial foot contact and contact time in experienced endurance runners at individualized speeds, in running shoes and barefoot. Forty-eight participants (33.71±7.49 y, 70.94±8.65 kg, 175.07±7.03 cm, maximum aerobic speed 18.41±1.54 km.h-1) were distributed into three groups according to athletic performance: highly-trained runners, middle-trained runners, and control group. An incremental running test until exhaustion was performed for assessing maximum aerobic speed. After≥24 h of recovery participants randomly walked and ran, barefoot and in running shoes, over a pressure plate at ~4.7 km.h-1 and 85% of the maximum aerobic speed, respectively. They wore the same model of running shoes with homogeneous lacing pattern. A rearfoot strike was performed by 68.8% and 77.1% of participants when running barefoot and in running shoes, respectively. Considering the tendency to develop a rearfoot strike was lower in the barefoot condition, runners with higher performance may benefit from training in minimalist running shoes because their foot contact pattern could tend towards a non-rearfoot strike. Our results suggest that initial foot contact and contact time are related to running performance and may also be influenced by running shoes.

This paper designs an outdoor landscape wall, which is equipped with an electrical motor, a sunlight intensity sensor and a rain sensor. The plants in the landscape wall will be rotated indoors when the weather is bad. To the contrary, based on signals from the sunlight intensity sensor, the plants can be rotated outdoors to get suitable sunlight. The dynamics of the electrical motor current control loop is much higher than the requirement of the position control loop. The whole control system can be divided into two subsystems: out-loop position control system and inner-loop current control system. An adaptive control strategy is proposed for out-loop position control. A nonlinear controller based on feedback linearization is developed for inner-loop current control. The two subsystems are synthesized with a first-order filter. Simulations are conducted to verify the proposed control strategy. The simulation results demonstrate that high-performance position tracking can be achieved under parameter uncertainty and disturbance.

We address the location-price decision problem for firms that offer the same type of product and compete on delivered pricing. If firms set equilibrium prices at demand points, the problem can be seen as a location game for which the Nash equilibrium (NE) is used as solution concept. For spatially separated markets, with inelastic demand, there exists a NE and it can be found by social cost minimization, as happens in network and planar location. However, with price sensitive demand, the existence of a NE has not been proven yet and socially optimal locations may not be a NE. In this paper we show that a NE can be found in discrete and network location when demand is price sensitive. A Mixed Integer Linear Programming formulation is implemented in the best response procedure which allow to find a NE for a variety of demand functions. An empirical study with data of Spanish municipalities is performed in which the procedure is applied to 200 large size test problems with linear, quadratic, exponential and hyperbolic demand functions.

Modern research has evolved several approaches toward skin regeneration and one of the novel concerns is the use of polymer-based systems due to their excellent beneficial properties to the skin. Several polymers, such as cellulose, hyaluronan, alginate, chitosan, collagen, fibrin and fibroin, have been tested and have proven the benefits for skin regeneration, and most of them are derived from either polysaccharide-or protein-based materials. In order to understand the mode of action, several researchers investigated the cell-matrix interaction and possible signaling mechanism in skin regeneration. Not only the signaling mechanism but also the mode of cell communication determines the application of polysaccharide-and protein-based polymers in practice. Based on the above significance, this review disclosed the recent findings to compile a possible method of communication between cells and polymers derived from polysaccharide-based (such as cellulose, hyaluronan, chitosan, alginate, agar, and xanthan gum) and protein-based (such as collagen, gelatin, fibrin, and silk fibroin) materials along with other polymers, such as poly(vinyl alcohol), polyglycolide or poly(glycolic acid), or poly(lactic acid) in skin regeneration. Accordingly, this review addresses the fundamental concept of cell-matrix communication, which helps us to understand the basis of the polymer's functions in the biomedical field.

Purpose In modern societies, motorcycle accidents have become a great problem for health systems worldwide. In Spain, the size and the power of the engine of 2-wheel vehicles determine the type of driving license and the age at which these vehicles can be used (mopeds and motorcycles, which at the same time can have a small or large engine capacity). The objective of the present study was to analyze and characterize low- and high-power motorcycle accidents in Spain, between 2014 and 2020, both included and compared these categories with each other. Methods Retrospective, descriptive, and observational study of motorcycle and moped accidents in Spain between 2014 and 2020, both included. Results The mortality of motorcycle accident riders in Spain is associated with males aged between 30 and 40 years old, with a high-power motorcycle, and an A or A1 driver’s license, who is 6.7 times more likely to die in crossings and highways than a moped, while wearing a helmet, and if not, this increases to 4.89 times. During the COVID-19 pandemic, an increase in death at 24 h after a high-power motorcycle accident was observed, as compared with a large reduction in the total medical assistance provided in 2019–2020. Conclusions High-power motorcycles had higher scores in mortality and morbity rates than low-power ones, with a significant increase in mortality during the pandemic, even though number of accidents and medical assistance provided were drastically reduced.

Background: Guidelines recommend pharmacological treatment for systolic blood pressure (SBP) of 130 to 139 mm Hg in secondary prevention. However, uncertainty persists in primary prevention in low cardiovascular risk patients (CVR). Methods: Cohort study representative of the general population of Albacete/Southeast Spain. We examined 1029 participants with untreated BP and free of cardiovascular disease, followed-up during 1992 to 2019. Cox regression modeled the association of SBP with cardiovascular morbidity and mortality (outcome-1) and cardiovascular morbidity and all-cause mortality (outcome-2). Results: Participants' mean age was 44.8 years (53.8%, women; 77.1% at low-CVR); 20.3% had SBP 120 to 129; 13.0% 130 to 139 at low-CVR and 3.4% at high-CVR; and 27.4% ≥140 mm Hg. After a 25.7-year median follow-up, 218 outcome-1 and 302 outcome-2 cases occurred. Unadjusted hazard ratios (HR) of outcome-1 for these increasing SBP categories (versus <120) were 2.72, 2.27, 11.54, and 7.52, respectively; and 2.69, 2.32, 10.55, and 7.34 for outcome-2 (all P<0.01). After adjustment for other risk factors, hazard ratio (95% CI) of outcome-1 were 1.49 (0.91-2.44), 1.65 (0.94-2.91, P=0.08), 1.36 (0.72-2.57), and 1.82 (1.15-2.88), respectively, and 1.39 (0.91-2.11), 1.69 (1.05-2.73), 1.09 (0.63-1.88), and 1.64 (1.11-2.41) for outcome-2. Compared with 130 to 139 at low-CVR, hazard ratio for 130 to 139 at high-CVR was 4.85 for outcome-1 (P<0.001) and 4.43 for outcome-2 (P<0.001). Conclusions: In this primary prevention population of relatively young average age, untreated SBP of 130 to 139 mm Hg at low-CVR had long-term prognostic value and might benefit from stricter SBP targets. High-CVR patients had nonsignificant higher risk (limited sample size) but 4-fold greater risk when compared with low-CVR. Overall, results indicate the importance of risk stratification, supporting risk-based decision-making.

The different nature of taekwondo and karate actions involves sport-specific actions with different physical demands and a typical morphological profile. The aims of the current investigation were to compare body composition and strength factors between young karate and taekwondo players and to investigate the body proportionality of each discipline. Twenty-five young taekwondo fighters (18 boys and 7 girls) and twenty-eight karate athletes (19 boys and 9 girls) volunteered for the study. A battery of anthropometric measurements were obtained for each individual (heights, weight, girths, lengths, and sum of skinfolds). Upper-body and lower-body strength were determined using the handgrip test and counter-movement jump test, respectively. In boys, significantly greater Σ 6 skinfold, wrist, and maximum thigh girth measurements were observed in taekwondo athletes (p < 0.05; d > 0.59), while karate competitors revealed larger muscle mass values (p < 0.05). Nevertheless, girls only showed significant differences with respect to anterior-posterior chest breadth, age at peak height velocity (APHV), and head girth (p < 0.05). Proportionality analysis revealed that both sexes presented lower skinfold thicknesses and breadths than the normal population. Therefore, in both disciplines, similar profiles were determined, but young karate athletes seemed to exhibit a tendency towards a more robust and compact profile with greater body strength.

Context: Despite the large number of studies published to date, the effect of lifestyle-based interventions on improving adherence to the Mediterranean diet (MedDiet) in young people has not been meta-analyzed. Objective: The aim of the present systematic review and meta-analysis was two-fold: (1) to determine the pooled intervention effects of lifestyle-based interventions on improving adherence to the MedDiet in a young population aged 3 years-18 years and (2) to examine the potential factors related to those intervention effects. Data sources: A systematic search of the MEDLINE (via PubMed), Scopus, Cochrane Library, and Web of Science databases was performed from their inception until June 15, 2023. Data extraction: Different meta-analyses were independently performed to observe the effect of lifestyle-based interventions on adherence to the MedDiet (according to the Mediterranean Diet Quality Index in children and adolescents [KIDMED]). Data analysis: Compared with the control group, the intervention group showed a small increase in KIDMED score (d = .27; 95% confidence interval [CI], .11 to .43; P < .001; I2 = 89.7%). Similarly, participants in the lifestyle-based intervention groups had a 14% higher probability of achieving optimal adherence to the MedDiet (risk difference = .14; 95% CI, .02 to .26; P = .023; I2 = 96.8%). Greater improvements in achieving optimal adherence to the MedDiet were found in interventions delivered out of school (risk difference = .24, 95% CI, .04 to .44; I2 = 88.4%), those aimed at parents or at both children and parents (risk difference = .20, 95% CI, .07 to .34; I2 = 98.2%), and those including only participants with overweight/obesity (risk difference = .34, 95% CI, .15 to .52; I2 = .0%). Conclusion: Healthy lifestyle-based interventions seem to be effective in increasing adherence to the MedDiet and in achieving optimal adherence to this dietary pattern among children and adolescents. Systematic review registration: PROSPERO registration no. CRD2022369409.

A single-center, randomized, double-blind, controlled clinical trial with four arms was conducted in healthy subjects with persistent knee discomfort (pain intensity on 1–10 cm visual analog scale (VAS) > 3) aged 40 years and older treated with a dietary supplement for 8 weeks. The study groups were Boswellia serrata extract (n = 29), an omega-3-based product (AvailOm® 50 High EPA) (n = 31), Boswellia + AvailOm® (n = 30), and placebo (n = 30). The intake of Boswellia + AvailOm® improved the quality of life (QoL) (WOMAC index) and some variables of muscle strength. Statistically significant differences between the AvailOm® and the placebo groups in the decrease of pain intensity were found. Weekly VAS scores showed a significant decrease in pain perception when comparing the AvailOm® product to the placebo, with the lowest VAS scores at week 8. Consumption of Boswellia improved sleep latency. The time to perform the Up and Go test decreased after the intake of AvailOm®. There was an increase in the omega-3 fatty acids, with the greatest increase in the Boswellia + AvailOm® group. AvailOm® was safe and effective in reducing pain and improving the QoL and functionality of subjects over 40 years with persistent knee pain.

Background: The main functions of healthcare professionals include training and health education. In this sense, we must be able to incorporate new technologies and serious game to the teaching cardiopulmonary resuscitation. Methods: a multicenter, comparative and cross-sectional study was carried out to assess the learning of resuscitation of a group that was trained with the use of serious gaming with virtual reality, as compared to a control group trained with conventional classroom teaching. Results: the mean quality obtained in chest compressions for the virtual reality group was 86.1 % (SD 9.3), and 74.8 % (SD 9.5) for the control group [mean difference 11.3 % (95 % CI 6.6-16.0), p < 0.001]. Salivary Alpha-Amylase was 218.882 (SD 177.621) IU/L for the virtual reality group and 155.190 (SD 116.746) IU/L for the control group [mean difference 63.691 (95 % CI 122.998-4.385), p = 0.037]. Conclusion: using virtual reality and serious games can improve the quality parameters of chest compressions as compared to traditional training.

Aim: In this study we present the new postoperative oro-myofunctional protocol following frenectomy by atmospheric plasma associated with a systemic postural approach, which determines functional recovery through body symmetry restoration based on the concepts of the French "Mezieres Method" and postural bench. Methods: A total of 130 patients (76 female, 54 male) affected by ankyloglossia of class III/IV, according to Kotlow's Tongue Tie Classification have been treated with atmospheric plasma followed by oro-myofunctional therapy associated with a systemic postural approach. The overall change, improved/worsened speech, feeding, or sleep has been evaluated through the 10 points Parents Speech Satisfaction (PSS) Score after one week and two months. Conclusion: Based on the findings of the current investigation, myofunctional therapy in tongue-tie results in a consistent significant functional ameliorating of feeding capability, speech and sleeping of subject treated as reported with traditional oro-myofunctional therapy.

Caffeoylquinic (5-CQA) and feruloylquinic (5-FQA) acids, found in coffee and other plant sources, are known to exhibit diverse biological activities, including potential antioxidant effects. However, the underlying mechanisms of these phenolic compounds remain elusive. This paper investigates the capacity and mode of action of 5-CQA and 5-FQA as natural antioxidants acting as hydroperoxyl radical scavengers and xanthine oxidase (XO) inhibitors. The hydroperoxyl radical scavenging potential was investigated using thermodynamic and kinetic calculations based on the DFT method, taking into account the influence of physiological conditions. Blind docking and molecular dynamics simulations were used to investigate the inhibition capacity toward the XO enzyme. The results showed that 5-CQA and 5-FQA exhibit potent hydroperoxyl radical scavenging capacity in both polar and lipidic physiological media, with rate constants higher than those of common antioxidants, such as Trolox and BHT. 5-CQA carrying catechol moiety was found to be more potent than 5-FQA in both physiological environments. Furthermore, both compounds show good affinity with the active site of the XO enzyme and form stable complexes. The hydrogen atom transfer (HAT) mechanism was found to be exclusive in lipid media, while both HAT and SET (single electron transfer) mechanisms are possible in water. 5-CQA and 5-FQA may, therefore, be considered potent natural antioxidants with potential health benefits.

Previous trials have demonstrated that modifying dietary fat composition can influence the production of inflammation-related factors. Additionally, it has been suggested that not only the type of fat, but also the timing of fat intake can impact these factors. Therefore, the objective of the present study was to evaluate the effect of altering breakfast fat composition on inflammatory parameters. A 3-month crossover randomized trial was designed, involving 60 institutionalized women who alternately consumed a breakfast rich in polyunsaturated fatty acids (PUFA) (margarine), monounsaturated fatty acids (MUFA) (virgin olive oil), or saturated fatty acids (SFA) (butter), based on randomization. The following inflammatory markers were evaluated: epidermal growth factor (EGF), interferon (IFN)-α, interleukin (IL)-1α, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor (TNF)-α, C-reactive protein (CRP), and vascular/endothelial growth factor (VEGF). The results showed that the most significant effects were observed with the high-MUFA breakfast, as there was a statistically significant decrease in plasma IL-6 (p = 0.016) and VEGF values (p = 0.035). Other factors, such as IL-1α and CRP, also decreased substantially, but did not reach the statistically significant level. On the other hand, the high-PUFA breakfast induced a significant decrease in EGF levels (p < 0.001), whereas the high-SFA breakfast had no apparent effect on these factors. In conclusion, modifying breakfast fat, particularly by increasing MUFA or PUFA intake, appears to be sufficient for promoting a lower inflammatory marker synthesis profile and may be beneficial in improving cardiovascular complications.

Glutathione S-transferase theta 1 (GSTT1) is an enzyme involved in phase II biotransformation processes and a member of a multigene family of detoxifying and clearing reactive oxygen species. GSTT1 is polymorphic like other biotransforming enzymes, allowing variability in hepatic conjugation processes. Immunological recognition of the GSTT1 alloantigen, as evidenced by donor-specific antibodies formation, has previously been observed in recipients lacking GSTT1 protein (called GSTT1-, GSTT*0, null phenotype or homozygous for the GSTT1 deletion) who receive liver or kidney transplants from GSTT1+ donors and is a risk factor for the development of de novo hepatitis following liver transplants from a GSTT1 expressing donor. Antibodies against GSTT1 are demonstrated in patients who are GSTT1 null and received a transplant from a GSTT1+ donor. Understanding the local population frequency of the GSTT1 deletion is of value in understanding the potential clinical risk of developing post-transplant complications, which can be attributed to the nonexpression of GSTT1. A population of 173 healthy donors of the Murcia Region in Southeast Spain was evaluated for a null allele of GSTT1 (n = 173). DNA was extracted, and GSTT-1 null allele detection was performed by real-time polymerase chain reaction. The frequency of the null GSTT1 genotype (nonexpression or deletion of the homozygous polymorphism of the GSTT1 protein) was 17.9% (n = 31 null allele GSTT1/173 total individuals). Our data suggest that the frequency of null GSTT1 mutations in our population in Southeast Spain is 17.9%, lower than in other Caucasoid populations. This would convert our recipient population into more susceptible to nonlocal potential organ donors and less susceptible to local donors. All recipients bearing this GSTT1 deletion homozygous would be without the protein and triggering an alloantigen in the case of transplantation with a donor without deletion.

Elite kayakers are characterized by robust somatotypes and a high degree of technical skills acquired from early ages along the biological maturity process. This study aimed to analyze the interdependence of anthropometric attributes, maturity status, and new stroke kinematics variables such as long- and short-term stroke steadiness in young sprint paddlers. Twenty-two elite young male canoeists, aged 13.5 ± 0.4 years, volunteered for the investigation. A battery of anthropometric measurements was obtained for each individual while stroke kinematics were determined by lateral recordings in an all-out 200 m test. Frame-to-frame analysis of consecutive strokes allowed the determination of short-term and long-term steadiness. Significant and positive correlations (p < 0.05) between maturity status, canoeing experience, and stroke steadiness were identified, especially in long-term steadiness (r = 0.60–0.83). In addition, upper-body dimensions in the chest and arms exhibited strong associations with both short- and long-term steadiness (p < 0.05). These findings suggest that biological maturity, but particularly experience, are key factors for a higher stroke efficiency. Therefore, early identification of morphological characteristics and maturity status along with specific practice in canoeing should be taken into consideration for ideal talent development in young canoeists.

Cycling is a very popular sport worldwide, and several studies have already indicated that cycling at various levels has a negative impact on bone health. This is of concern to both performance and health managers of many cycling teams at different levels because of its economic and social impact. Based on the scientific literature, we hypothesize that a single season at the professional level can negatively affect bone health status. The aim of this study was to assess how professional cycling affects bone health markers after one season. Densitometry was used to measure the bone mineral density (BMD), bone mineral content (BMC), bone area (BA), fat mass (FM), fat-free mass (FFM), T-score and Z-score in professional cyclists after one season. After one season at the professional level, cyclists' BMD decreased significantly in the legs, trunk, ribs and pelvis (p ≤ 0.05). BMC decreased in the arms and spine (p ≤ 0.05). BA decreased significantly in the arms and spine (p ≤ 0.05). In addition, a significant decrease in Z-score (p ≤ 0.05) and a decreasing trend in T-score and total BMD (p = 0.06) were observed. One season of professional cycling is enough to negatively affect bone health status.