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ABSTRACT: A dessert matrix previously used for diagnosis of food allergies was incurred with pasteurised egg white or skimmed milk powder at 3, 6, 15 and 30mg allergen protein per kg of dessert matrix and evaluated as a quality control material for allergen analysis in a multi-laboratory trial. Analysis was performed by immunoassay using five kits each for egg and milk (based on casein) and six 'other' milk kits (five based on β-lactoglobulin and one total milk). All kits detected allergen protein at the 3mgkg(-1) level. Based on ISO criteria only one egg kit accurately determined egg protein at 3mgkg(-1) (p=0.62) and one milk (casein) kit accurately determined milk at 6 (p=0.54) and 15mgkg(-1) (p=0.83), against the target value. The milk "other" kits performed least well of all the kits assessed, giving the least precise analyses. The incurred dessert material had the characteristics required for a quality control material for allergen analysis.
Article: Disruptive influence[Show abstract] [Hide abstract]
ABSTRACT: Cachexia, a condition that kills about one-fifth of cancer patients, may be linked to Rb-a protein that is already linked to various cancers-moving from the cell nucleus to the cytoplasm.
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