Tamil Nadu Dr. M.G.R. Medical University

AI-driven “audiomics” leverages voice and respiratory sounds as non-invasive biomarkers to diagnose and manage pulmonary conditions, including COVID-19, tuberculosis, ILD, asthma, and COPD. By analyzing acoustic features, machine and deep learning enhance diagnostic accuracy and track disease progression. Key applications include cough-based TB detection, smartphone COVID-19 screening, and speech analysis for asthma and COPD monitoring. Ethical challenges like data privacy and standardization remain barriers to clinical adoption. With ongoing research, audiomics holds promise for transforming respiratory diagnostics and personalized care.

Cervical lymphadenopathy can be due to numerous causes. The common causes include reactive and infections conditions in children and malignancy in the elderly. Kikuchi-Fujimoto disease (KFD) is a rare cause of cervical lymphadenopathy. As viral vaccines contain viral antigens, they can trigger the development of KFD. The human papillomavirus (HPV) vaccine can trigger KFD. It is important to elicit a history of prior vaccination to identify the trigger in patients with necrotising histiocytic lymphadenitis suspected of having KFD. We hereby report a case of a 16-year-old female who was diagnosed with HPV vaccine induced KFD. Ours is the first case to be reported from India. Histopathology revealed necrotising histiocytic lymphoid hyperplasia and the absence of neutrophils, eosinophils, plasma cells, vessel wall vasculitis, haematoxylin bodies, and Reed-Sternberg cells, and negative aerobic, MTB cultures, anti-nuclear antibodies, clinched the diagnosis of KFD.

Introduction This scoping review was conducted to ascertain the loss of heterozygosity (LOH) signatures reported in Oral Potentially Malignant Disorders (OPMD) and Oral Squamous Cell Carcinoma (OSCC), in the literature in the last fifty years. Methods The Joanna Briggs Institute recommendations (2023) for scoping review were used to extract, analyze, and present the results. The review was reported according to the PRISMA guidelines for Scoping Reviews (PRISMA-ScR). The most commonly reported genes associated with LOH in OPMD and OSCC are discussed. The Gene Ontology functional enrichment analysis gives the significance of the protein–protein interactions (PPI) of these genes using the STRING database. Results An exhaustive database search of the title, abstract, and full-text screening consistent with the eligibility criteria yielded 277 studies. LOH commonly studied in OPMD and OSCC include p53 gene, p16 gene, adenomatous polyposis coli gene, retinoblastoma (Rb) gene, fragile histidine triad (FHIT) gene and phosphatase and tensin homolog (PTEN) gene. Chromosome loci involving 17p, 9p, 5q, 13q, 3p, and 10q were frequently reported in OPMD and OSCC. PPI analysis demonstrated strong evidence of p53 interaction with p16, FHIT, and Rb. Conclusion Distinctive signatures of LOH are seen in OPMD and OSCC. The LOH patterns identified in this scoping review underline the significance of advanced molecular techniques and the need for long-term prospective cohorts to understand LOH pathophysiology in oral carcinogenesis to enable their usefulness as biomarkers in early diagnosis, treatment, and prognostication of oral cancer.

A BSTRACT Bronchiectasis is the permanent dilatation of the bronchi, which is classified into cylindrical, varicose, and cystic bronchiectasis. Hence, it is a rare opportunity to visualize structural bronchoscopic finding in a case of bronchiectasis. Awareness of this image helps bronchoscopists to identify and classify this bronchoscopic appearance of bronchiectasis.

Madhumukthi Kudineer Chooranum (MKC) is a decoction from polyherbal Siddha formulation for managing diabetes. The safety of this formulation has not been reported earlier. This study evaluates the chronic toxicity of the Siddha herbal formulation MKC in experimental Sprague–Dawley (SD) rats. In an acute oral toxicity study, male and female SD rats were orally administered a single dose of MKC (2000 mg/kg), and clinical signs and mortality stages were observed for 14 days along with weekly body weight. On day 15, the rats were euthanized and the gross morphology was carried out during necropsy. In a chronic (repeated dose) oral toxicity study, the male and female rats were orally administered MKC (200, 400, and 800 mg/kg) once daily for up to 180 days. MKC showed outstanding tolerance in SD rats with a NOAEL of 2000 mg/kg, with no adverse effects or death during the study. In acute and chronic toxicity trials, MKC did not alter parameters or cause harmful effects. No group died or became moribund in either study.

Background: Benson's relaxation therapy is a nursing intervention that can be used as complementary and non-pharmacological therapy. Benson's relaxation therapy is one of the relaxation technique that is easily learned by the patient with its simpler cost-effective intervention. Aim And Objectives: To evaluate the effectiveness of Benson's relaxation therapy on pain and stress among caesarean section mothers. Method: Quantitative research approach, true experimental research design was used.60caesarean mothers were selected using simple random sampling technique through lottery method, divided into experimental and control group each group consist of 30 samples mothers. The study was conducted at Unitta's Multispecialty Hospital, Chennai. Results: The pretest mean score of pain was 7.20±2.86 and the post-test mean score of pain was 0.97±1.33. The mean difference score was 6.23 (62.3%). The calculated paired 't' test value of t = 10.131 was found to be statistically highly significant at p<0.001 level. The pretest mean score of stress was 50.13±.7.64 and the post-test mean score of stress was 25.17±11.74. The mean difference score was 24.96 (31.2%). The calculated paired 't' test value of t=17.440 was found to be statistically highly significant at p<0.001 level. Conclusion: This infers that Benson's relaxation therapy administered to caesarean section mothers in the experimental group was found to be effective in reducing the level of pain and stress.

BACKGROUND: Respiratory tract infections (RTIs) are infectious disease that can affect the throat ,sinuses, airway, or lung. They are generally categorized as upper and lower respiratory tract infections (URTIs or LRTIs) Symptoms include cough, sore throat, runny or stuffy nose, sneezing, headache, muscle aches, and low-grade fever. AIMS AND OBJECTIVES: This study aimed to 1.To assess the pretest and post-test level of physiological parameters among children with respiratory tract infection.2.To evaluate the effectiveness of respiratory therapy on physiological parameters among children with respiratory tract infection.3.To find out the association of post-test level of physiological parameters among children with respiratory tract infection with their selected demographic variables. METHODOLOGY:A quantitative research approach with a pre-experimental research design was used for the study.60 children were selected using purposive sampling techniques. The study was conducted in a selected pediatric hospital chennai. The Paediatric Early Warning Scoring (PEWS) tool was used to assess physiological parameters. RESULTS: The results showed that in the pre-test, The majority of the children 11(18.33%) had mild respiratory tract infection, 37(61.67%) had moderate respiratory tract infection and 12(20%) had severe respiratory tract infection. Where as in the post-test, 53(89%) had mild respiratory tract infection, 5(8%) had moderate respiratory tract infection and 2(3%) had severe respiratory tract infection. Paired t-test revealed that Respiratory therapy ( RT) had a statistically significant effect on improving respiratory parameters such as Respiratory Rate (RR),Heart Rate (HR),Capillary Refill Time, Level of Consciousness and Oxygen saturation at (P<0.05)level. CONCLUSION: The findings of this study implies that respiratory therapy was effective to improve the physiological parameters among children with respiratory tract infection.

Background: Sleep is one of the components of mental and physical health in old age. The quality of sleep has been decreasing among most of the elderly. Chronic illness, physical disabilities, mental illnesses and other co morbidities are more prevalent among the elderly leading to poor sleep quality. Nurse led intervention like sleep hygiene, white noise and back massage can be used as a simple non- pharmacological therapy to improve the quality of sleep. Aim and objective: To evaluate the effectiveness of Nurse led interventions on sleep quality among elderly. Methodology: Quantitative research approach, Pre experimental research design was used.77 elderly were selected using total enumeration sampling technique. one group pre-test-post- test. The study was conducted at Bhagavatha Uthamargal old age home, Marakkanam, Results: The pretest mean score of overall sleep quality was 16.03±1.57 and the post-test mean score was 0.97±1.95. The mean difference was 15.06.The calculated paired 't' test value for subjective sleep quality (t=31.255, p=0.0001), sleep latency (t=41.871, p=0.0001), sleep duration (t=47.788, p=0.0001), habitual sleep efficiency (t=16.088, p=0.0001), sleep disturbances (t=44.211, p=0.0001), daytime dysfunction (t=35.754, p=0.0001) and the overall sleep quality (t=50.898, p=0.0001) was found to be statistically significant at p<0.001 level. Conclusion: This clearly infers that nurse led interventions administered to the elderly was found to be effective in reducing the sleep difficulty among elderly.

Benign smooth muscle tumours, known as leiomyomas, are comparatively frequent, with uterine cases accounting for 95% incidence. Oral leiomyomas typically appear as asymptomatic, slowly-growing submucosal lumps in the tongue, hard palate, or buccal mucosa. Three histologic kinds of leiomyomas are recognized: epithelioid leiomyoma, solid leiomyoma, and angioleiomyoma. The most prevalent type of leiomyomas affecting the oral cavity are solitary forms called angioleiomyomas, which typically develop in the subcutis. The diagnosis is commonly determined by histopathological and Immunohistochemistry (IHC) procedures. This case reports a 30-year-old female patient with a lesion on her right cheek region. The postsurgical specimen was routinely processed and stained with hematoxylin and eosin staining, and IHC studies confirmed the diagnosis of ‘Benign spindle cell neoplasm—Angioleiomyoma’.

Background Oral mucoceles are common lesions involving the salivary glands, characterized by mucous extravasation or retention phenomena. Despite their prevalence, they are often underreported, leading to potential diagnostic challenges and oversight of unusual presentations. This retrospective study aimed to analyze the clinical characteristics, demographic trends, and management outcomes of oral mucoceles over a 10-year period. Materials and Methods A retrospective analysis was conducted on archival data from January 2014 to January 2024. Cases with a confirmed diagnosis of mucoceles based on histopathological examination were included. Data regarding demographic characteristics, anatomical site of mucocele, clinical presentation, biopsy type, and follow-up information were collected and analyzed using descriptive statistics. Results Out of 58 clinically diagnosed mucocele cases, 53 were confirmed histopathologically. The mean age of the reviewed cases was 24.3 ± 16.5 years, with a male predominance (60.4%). Mucoceles predominantly affected the lower lip (62.3%), followed by the lip region (13.2%). Excisional biopsy was the preferred treatment modality (88.7%), with the mucous extravasation phenomenon being the predominant histopathological diagnosis (98.1%). Recurrence was observed in one case (1.9%). Conclusion This study contributes to understanding the prevalence, clinical characteristics, and management outcomes of oral mucoceles. The findings emphasize the importance of accurate diagnosis and appropriate management strategies to optimize patient care and outcomes.

Aim This study aims to evaluate the impact of adding bilateral hamstring muscle stretching to pressure pain threshold and ultrasound therapy, compared to using pressure pain threshold and ultrasound therapy alone, on pain reduction and maximum vertical mouth opening (MVMO) in individuals with temporomandibular disorders (TMD). Materials and methods A total of 56 participants diagnosed with TMD were randomly allocated into 2 groups: The Experimental Group, which received bilateral hamstring stretching, pressure pain threshold application, and ultrasound therapy, and the control group, which received only pressure pain threshold and ultrasound therapy. The study included participants of both genders, aged between 18 and 35 years, with a previous history of TMD pain lasting no longer than 6 months. Assessments were conducted at baseline and after 5 treatment sessions per week over 1 week. Pain levels were measured using the visual analog scale (VAS), and MVMO was assessed using a vernier caliper. Data were recorded and statistically analyzed. Results The results showed a significant reduction in pain and an increase in MVMO in both groups. In the Experimental Group, the mean pain score on the VAS decreased from 6.8 ± 1.2 to 2.9 ± 1.1, whereas in the control group, it decreased from 6.7 ± 1.3 to 4.1 ± 1.2 (p < 0.001). Similarly, MVMO improved significantly, with an increase from 31.4 ± 2.6 mm to 39.8 ± 2.1 mm in the Experimental Group, compared to an increase from 31.2 ± 2.8 mm to 36.1 ± 2.4 mm in the control group (p < 0.001). The between-group comparison showed a significant difference in pain reduction and MVMO improvement in the Experimental Group compared to the control group (p < 0.001). Conclusion Hamstring stretching combined with ultrasound therapy and pressure pain threshold application was significantly more effective in reducing TMD-related pain and improving MVMO than pressure pain threshold and ultrasound therapy alone. These findings indicate that integrating hamstring stretching into TMD treatment protocols could improve rehabilitation outcomes. Clinical significance The findings of this study highlight the potential benefits of integrating hamstring stretching into standard physiotherapy interventions for TMD. Given the significant improvements observed in pain reduction and MVMO, clinicians may consider including hamstring flexibility exercises in rehabilitation programs for TMD patients to achieve better functional outcomes. How to cite this article Irusappan S, Kurusumuthu FSM, Ramachandran S. Efficacy of Hamstring Stretching, Ultrasound Therapy, and Pressure Pain Threshold for Masseter Muscle in TMJ Dysfunction Patients: A Randomized Controlled Trial. J Contemp Dent Pract 2025;26(1):34–39.

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by systemic involvement, inflammation , and the destruction of synovial joints. RA can be categorized as anti-citrullinated protein antibodies-positive or negative based on genetic risk factors and autoantibodies. This review systematically sourced articles related to RA, phytocompounds, signaling pathways, and clinical insights from primary medical databases, including Scopus, PubMed, and Web of Science. This review explores the therapeutic potential of phytocompounds in treating RA by targeting key inflammation and immunological response signaling pathways. Phytocompounds such as curcumin, resveratrol, and flavonoids alter essential molecular pathways in RA pathophysiology, including nuclear factor kappa-light-chain-enhancer of activated B cells, mitogen-activated protein kinases, janus ki-nase-signal transducer and activator of transcription, and the inflammasome. These substances possess pro-resolving, anti-apoptotic, and antioxidant properties, which enhance their therapeutic efficacy. Alternative medicine , including dietary, herbal, and nutritional supplements, may help reduce RA symptoms. In vitro, in vivo, and clinical studies have demonstrated the effectiveness of these treatments. Phytocompounds have potential as a treatment for RA by altering signaling pathways, reducing oxidative stress, and protecting cartilage and bone. However, few clinical trials confirm its long-term safety, bioavailability, and effectiveness. Further clinical trials and translational research are needed to validate the effectiveness, safety, and pharmacokinetics of phytocompounds, while identifying novel plant-derived bioactive chemicals could improve patient outcomes.

Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, significantly increases the risk of thromboembolism and stroke. Its coexistence with valvular heart disease (VHD) further complicates management due to elevated risks of thromboembolism, bleeding, and mortality. This review explores the pathophysiology of AF and its interaction with VHD, focusing on diagnostic tools like echocardiography and risk stratification scores such as CHA2DS2-VASc and HAS-BLED. Vitamin K antagonists (VKAs) remain the cornerstone of anticoagulation therapy in high-risk VHD populations, particularly in patients with mechanical heart valves or moderate-to-severe mitral stenosis (MS). VKAs have demonstrated proven efficacy in reducing thromboembolic events in these subgroups, supported by decades of clinical evidence. However, their use requires frequent international normalized ratio (INR) monitoring and is associated with higher bleeding risks, posing challenges in long-term management. Despite these limitations, VKAs are indispensable in these populations due to the lack of robust evidence supporting the safety and efficacy of direct oral anticoagulants (DOACs) in these high-risk groups. Ongoing clinical trials, such as the RIVER trial, aim to evaluate the role of DOACs in VHD. However, current guidelines continue to recommend VKAs as the standard of care for these patients. In contrast, DOACs offer significant advantages in non-valvular AF and selected VHD populations. Their predictable pharmacokinetics, fewer dietary restrictions, and lower risks of intracranial hemorrhage make them a preferred choice for many patients. Landmark trials and meta-analyses, including RE-LY, ROCKET-AF, and ARISTOTLE, have demonstrated the safety and efficacy of DOACs in non-valvular AF and certain VHD subgroups. However, DOACs are contraindicated in high-risk VHD populations, such as those with mechanical valves or moderate-to-severe MS, due to insufficient evidence and potential risks of thromboembolic events. Evolving guidelines from leading societies emphasize individualized approaches and collaborative decision-making in anticoagulation therapy. While DOACs are preferred for most AF patients, VKAs remain essential for high-risk VHD patients. Future advancements, such as factor XIa inhibitors, hold promise for improving outcomes and safety in these complex populations. This review provides a comprehensive framework for clinicians to navigate the complexities of anticoagulation in AF and VHD, ensuring evidence-based, patient-centered care.

Abernethy malformation is a rare congenital vascular anomaly of the splanchnic venous system, leading to portosystemic shunting and related symptoms. A 7-month-old child was admitted with cyanosis and respiratory distress. Echocardiography revealed dilated biatrium and left superior vena cava into the coronary sinus. A bubble contrast study suggested pulmonary arteriovenous malformation (AVM) necessitating cardiac catheterization study for embolization. The child was induced with fentanyl, ketamine, and vecuronium after preoxygenation. Hypothermia prevention and measures to address pulmonary venous resistance including air embolism were implemented. The study confirmed bilateral pulmonary AVM and Type 1b Abernethy malformation. Given the complexity of the procedure, the parents were counseled for liver transplant. The management focuses on hemodynamic stability, to mitigate air embolism, counteract intraoperative pulmonary hypertension, and ensure adequate anesthesia and analgesia.

Neural tube defects (NTDs) are severe congenital anomalies affecting 1–2 infants per 1000 births, and are influenced by genetic and environmental factors, with DNA hypomethylation and methylation cycle suppression being key causes. In our earlier investigation, decitabine (DCT) caused multiple NTDs in embryonic zebrafish, supporting this hypothesis. Recent research has emphasized the importance of myo-inositol (MI) in embryonic development and its efficacy in reducing the risk of neural tube defects, even in cases resistant to folate. We aimed to examine the effect of MI on DCT-induced NTDs in an embryonic zebrafish model. The embryos were exposed to 1 mM DCT alone, 50 µM MI with 1 mM DCT, 100 µM MI with 1 mM DCT, and a control group for comparison. The development, hatching, mortality rates, neural tube malformations, and neural tube patterning of developing embryos were monitored and recorded. Exposure to MI significantly reduced the incidence of NTDs in developing embryos. At concentrations of 50 µM and 100 µM, MI provided 35% and 30% protection against DCT-induced neural tube malformation, respectively. Multiple NTDs were significantly reduced in the MI groups, with 1 mM DCT causing 95% defects, 50 µM MI with 1 mM DCT causing 50%, and 100 µM MI with 1 mM DCT causing 55% defects. The DCT-induced hatching delay was also reversed by MI treatment. Alizarin red staining and histopathological observations supported these observations. In the context of neural tube development, the protective effects of MI against DCT-induced NTDs could be attributed to its potential role in epigenetic regulation, which may influence genetic expression.

Chronic Hepatitis B Virus (HBV) infection remains a formidable global health challenge, driving severe liver complications such as hepatocellular carcinoma (HCC) and pyogenic liver abscesses (PLA). At the core of HBV persistence lies covalently closed circular DNA (cccDNA), a viral reservoir that fuels ongoing infection despite antiviral treatments. This review highlights molecular mechanisms governing cccDNA formation, maintenance, and clearance, spotlighting innovative therapeutic strategies to disrupt this key viral element. We explore cutting-edge approaches, including epigenetic modulation to silence cccDNA, RNA interference (RNAi) for viral RNA degradation, and CRISPR/Cas genome editing to excise cccDNA directly. Additionally, emerging antiviral therapies and immunotherapies, such as therapeutic vaccines and immune checkpoint inhibitors, offer new avenues for enhanced treatment efficacy. Special attention is given to the clinical complexities of managing HBV in patients with co-morbid conditions like HCC and PLA, emphasizing the necessity of a multidisciplinary approach. The interplay between antibacterial and antiviral therapies in PLA-associated HBV cases is critically examined to prevent treatment antagonism, ensuring optimal patient outcomes. Advanced therapeutic strategies, including nucleos(t)ide analogs, interferon therapy, and novel genomic interventions, are explored in both isolated HBV infection and PLA co-infections. Personalized regimens remain pivotal in enhancing therapeutic efficacy and long-term disease control. Current review advocates for a shift toward precision medicine, highlighting the critical need for interdisciplinary collaboration to bridge molecular discoveries with clinical innovations. Ultimately, these advancements promise to revolutionize the management of chronic HBV, paving the way for potential cures and improved patient outcomes.

Background Several biomarkers, including C-reactive protein (CRP), ferritin, D-dimer, and Interleukin-6 (IL-6), are established predictors of disease severity and respiratory failure in patients with COVID-19. Objective In this randomised clinical study, we evaluated the efficiency of the combination of 2 variants’ AFO-202 and N-163 strains of Aureobasidium pullulans produced 1,3-1,6 β-glucans in comparison with the control arm on these biomarkers in COVID-19 patients. Methods Forty RT-PCR positive COVID-19 patients were divided into 2 groups: control (n = 22) and standard treatment; ii. (n = 18) – Standard treatment + combination of AFO-202 and N-163 beta glucans for 15 days. Results IL-6 levels significantly decreased in the treatment group on day 7 ( P = 0.03) but not by day 15 ( P = 0.30). CRP levels in the treatment group decreased at day 7 (5.53 ± 8.21 mg/L) compared to baseline but showed no significant difference from the control group (4.91 ± 12.54 mg/L, P = 0.98). At day 15, CRP levels remained lower in the treatment group (5.42 ± 10.41 mg/L) but increased in the control group (14.0 ± 37.16 mg/L), with no significant difference ( P = 0.52). Ferritin levels dropped significantly in the treatment group by day 15 (from 560.58 ± 537.30 ng/mL to 127.51 ± 215.91 ng/mL) but increased in the control ( P = 0.98). D-dimer levels decreased in the treatment group by day 15 but were not significantly different from controls ( P = 0.56). Conclusion These results indicate that while co-supplementation with AFO-202 and N-163 beta-glucans led to improvement in CRP, ferritin, and IL-6 levels in COVID-19 patients, only the reduction in IL-6 levels on day 7 reached statistical significance. Further long-term multicentric clinical research is warranted to validate the potential of these supplements as treatment adjuncts, for addressing inflammation in COVID-19, especially in vulnerable populations infected with emerging SARS-CoV-2 variants.

Deoxyribonucleic acid (DNA) is the crucial molecule that stores and transmits genetic information in living organisms. DNA can incur damage from various sources, ne-cessitating efficient DNA repair mechanisms to maintain genomic stability. Cells employ multiple repair pathways, including single-strand repair and double-strand break repair, each involving specific proteins and enzymes. PARPs play a fundamental role in the repair of DNA to detect damage to DNA and facilitate the repair process. PARPi are drugs that inhib-it PARP activity, leading to DNA damage accumulation and cell death, particularly in can-cer cells with impairments in DNA repair pathways, such as BRCA1/2 mutations. Addition-ally, PARPi is promising in treating cancer, offering a targeted therapeutic approach. Re-sistance to PARP inhibitors continues to be an issue in a major clinical challenge. Mecha-nisms of resistance include homologous recombination repair restoration, increased drug ef-flux, and mutations in the PARP1 enzyme. Moreover, to overcome this resistance, research-ers are investigating combination therapies, targeted therapies that inhibit complementary DNA repair pathways, and novel agents that can counteract resistance mechanisms. Future perspectives focus on enhancing our understanding of resistance mechanisms, developing more effective and selective PARP inhibitors, and identifying predictive biomarkers for therapy response. These advancements aim to improve the efficacy and durability of PARP inhibitor-based treatments, ultimately leading to better outcomes for cancer patients. This review article focuses on the reasons for the evolution of PARP inhibitors, the mechanisms behind resistance, and new strategies to overcome this resistance.

A deep-vein thrombosis (DVT) is a blood clot that forms within the deep veins, usually of the leg, but can occur in the arms and the mesenteric and cerebral veins. Deep-vein thrombosis is a common and important disease. Deep-vein thrombosis is a major medical problem accounting for most cases of pulmonary embolism1 The present study aims to determine the risk for deep vein thrombosis and the preventive strategies among patients admitted in critical care unit.2 Objective: The objective of the study is to determine the determine the risk for deep vein thrombosis and the preventive strategies among patients admitted in critical care unit. Methodology: A Cross sectional descriptive research design was adopted for the study. The study was carried out on 50 samples of critical care patients at Apollo Hospitals, Chennai After obtaining the setting permission and informed consent from participants, data was collected using pretested and validated tools such as background variable proforma of adults such as age, gender, religion, marital status, occupation, monthly income, educational status, type of family and Health insurance and clinical variables of adults such as height, weight, BMI, PT, PTT, INR, BT, CT and D-dime. WELLS Criteria to assess the Risk level of DVT among Critical Care Patients. Observation Check list to assess the Practice of Preventive strategies for DVT among Critical Care Patients Data was collected by a self -administration method using questionnaire method. The main data collection was done after determining feasibility and practicability by pilot study. The data was tabulated and analysed by using descriptive and inferential statistics. Results: The majority of the critical care patients had low level risk for development of deep vein thrombosis (70%), 28% of them had moderate risk and 2% of them are high risk respectively. Conclusion: The study determines the relationship between aims to determine the risk for deep vein thrombosis and the preventive strategies among patients admitted in critical care unit.