Singhania University
  • Jhunjhunūn, India
Recent publications
The stock market is a popular investment option for investors because of its expected high returns. Stock market prediction is a complex task to achieve with the help of artificial intelligence. Because stock prices depend on many factors, including trends and news in the market. However, in recent years, many creative techniques and models have been proposed and applied to efficiently and accurately forecast the behaviour of the stock market. This paper presents a comparative study of fundamental and technical analysis based on different parameters. We also discuss a comparative Analysis of various prediction techniques used to predict stock price. These strategies include technical analysis like time series analysis and machine learning algorithms such as the artificial neural network (ANN). Along with them, few researchers focused on the textual analysis of stock prices by continuous analysing the public sentiments from social media and other news sources. Various approaches are compared based on methodologies, datasets, and efficiency with the help of visualisation.
For a pathogenic microbe to cause disease in a susceptible host, it must gain access to that host first. The pathogenicity of a microbe is determined by the virulence factors alongside other innate mechanisms. Apart from the initiation of infection, these virulence factors also enable the pathogenic microorganism to survive in the new environment within the susceptible host. They also enable the pathogenic microorganism to invade the host, colonize, and evade the host defense mechanisms. These virulence factors include; invasins, capsules, siderophores, adhesins, enzymes, endotoxins, and exotoxins. Key words: Pathogenicity factors and Pathological effect on cells.
The energy issues of Wireless Sensor Networks are mainly addressed through use of clustering and data aggregation. Of late, fuzzy logic is being employed for cluster head election. A recent work has designed fuzzy rules for both CH election and member selection. Though the idea is strong, it may leave a few nodes isolated. We present few modifications to existing work of unequal clustering through fuzzy logic so that the nodes left uncovered in the network get reduced or are included in cluster structure. Three modifications suggested here improve the performance of protocol by extending network lifetime manifold. Also, it gives insight into all such protocols that are based on principles of LEACH and use fuzzy logic for homogeneous networks.
Silicon (Si) is known to alleviate the adverse impact of different abiotic and biotic stresses by different mechanisms including morphological, physiological, and genetic changes. Photosynthesis, one of the most important physiological processes in the plant is sensitive to different stress factors. Several studies have shown that Si ameliorates the stress effects on photosynthesis by protecting photosynthetic machinery and its function. In stressed plants, several photosynthesis-related processes including PSII maximum photochemical quantum yield (Fv/Fm), the yield of photosystem II (ϕPSII), electron transport rates (ETR), and photochemical quenching (qP) were observed to be regulated when supplemented with Si, which indicates that Si effectively protects the photosynthetic machinery. In addition, studies also suggested that Si is capable enough to maintain the uneven swelling, disintegrated, and missing thylakoid membranes caused during stress. Furthermore, several photosynthesis-related genes were also regulated by Si supplementation. Taking into account the key impact of Si on the evolutionarily conserved process of photosynthesis in plants, this review article is focused on the aspects of silicon and photosynthesis interrelationships during stress and signaling pathways. The assemblages of this discussion shall fulfill the lack of constructive literature related to the influence of Si on one of the most dynamic and important processes of plant life i.e. photosynthesis.
Using coupled mode approach, we perform an analytical investigation of hot carrier effects (HCEs) of pump wave on (steady-state and transient) Brillouin gain coefficients of magnetoactive doped semiconductors. The threshold condition for exciting transient stimulated Brillouin scattering phenomenon is estimated. Numerical calculations are made for n-InSb crystal—CO2 laser system. Efforts are made to obtain enhanced values of Brillouin gain coefficients and lower threshold intensity by suitably choosing plasma and cyclotron frequencies around resonances. HCEs of intense pump wave modify the momentum transfer collision frequency of carriers and consequently the nonlinearity of the Brillouin medium, which in turn (1) lowers threshold intensity, (2) enhances Brillouin gain coefficients, (3) shifts the enhanced Brillouin gain spectrum toward smaller values of magnetic field, and (4) widens the range of magnetic field at which peak of Brillouin gain spectrum (around resonance) occurs. The inclusion of HCEs in the analysis leads to better understanding of laser-semiconductor interactions and validate the possibility of chosen Brillouin medium as a potential candidate material for the fabrication of widely tunable and efficient Brillouin amplifiers and oscillators.
Objectives The anti-inflammatory activity of Boswellia serrata extracts (BSE) is well known. BSE comprises boswellic acids (BA) such as 3- O -acetyl-11-keto- beta -boswellic acid (AKBA) and 11- keto -boswellic acid (KBA) as major constituents. One of the limitations of BAs is their poor oral bioavailability. The aim of the study was to prepare solid lipid particles of Boswellia serrata extract (SLBSP) to enhance the bioavailability of BAs. Methods The pharmacokinetic profile of BAs was studied in 10 healthy human volunteers following a single oral dose of 333 mg of SLBSP. Pharmacokinetic blood samples were collected at 0.5, 1, 1.5, 2, 2.5, 3, 4, 5, 6, 8, and 12 h post drug administration. Plasma KBA and AKBA levels were measured using a validated LC-MS/MS method. Pharmacokinetics parameters were estimated using Pheonix WinNonlin (Build 6.4.0.768) software. Results Ten healthy human volunteers were included and peak plasma concentration was achieved in 1.5 and 2.3 h for AKBA and KBA respectively. Maximum plasma concentration ( C max ) was 8.04 ± 1.67 ng/mL for AKBA and 23.83 ± 4.41 ng/mL for KBA whereas the corresponding area under the concentration-time curve (AUC) was 136.7 ± 56.77 ng/mL*h and 165.7 ± 24.5 ng/mL*h respectively. The elimination half-life ( t 1/2 ) of AKBA and KBA was 6.8 ± 3.0 h and 2.45 ± 0.3 h respectively. Conclusions The SLBSP formulation of BSE showed enhanced oral bioavailability of BAs compared with historically reported data of unformulated BSE.
Objective: To compare the rate of sperm survival and motility through semen freezing and thawing during infertility treatment. Methodology: In this bidirectional observational study, we enrolled 31 patients who underwent semen analysis for infertility treatment at the Institute of Reproduction and Child Cares & IRCC IVF Centre, Panchkula, Haryana, from June 2020 to December 2020. Out of these patients, 21 (67.74 %) were considered for semen freezing and thawing. For the rest of the ten patients (32.25 %), sperm count and motility were not good, and we excluded them from this study. Semen freezing based upon sperm count and motility were done. We did semen thawing after two weeks of semen freezing and recorded the sperm survival and motility. Results: Post thaw sperm survival rate and motility was 37.66% compare to pre-cryopreservation (61.82%). The observed rate of sperm motility declining was 24.16 % after cryopreservation/freezing. Conclusion: The present study results concluded that sperm's cryopreservation results in a decrease in sperm motility. There is a need of finding more accurate and reliable methods to freeze and thaw semen.
Test tube baby is always a fascinating field of human reproductive biological science playing an important role in treating infertility. Poor semen quality is the major cause of infertility in human beings. Preparation of semen samples for intrauterine insemination (IUI) or in-vitro fertilization (IVF) is a key point in the success of test-tube embryo production. The study compared two different methods of semen preparation viz. double density gradient (DDG) and single density gradient (SDG) in patients seeking IUI / IVF treatment with their consent and permission of the hospital. Semen ejaculate from patients (n=100) was divided equally into two equal volume parts. One half of each sample was treated with DDG and another half with the SDG method of semen preparation. Results showed that sperm concentration was significantly higher (P>0.05) in SDG compared to DDG treated samples which were 58.65±181 and 49.89±180 Million/ml, respectively. Sperm motility of type-a and type-b both were significantly higher (P>0.05) in SDG compared to DDG treated samples which were 91.85± 3.15 and 68.85 ± 26.15. It is concluded that the single density gradient method is better than the double density gradient for semen ejaculates preparation during the treatment of male infertility using the in-vitro fertilization technique.
A comparative regeneration of three types of explants prepared from axillary meristems, plumular apices and hypocotyls of chickpea (Cicer arietinum) was carried out using four thidiazuron (TDZ) treatment methods. The first and third ones included the short-term 20 μM TDZ pre-treatment for all three explant types followed by non-supplementation or supplementation of TDZ (4 μM) into the shoot induction medium (SIM), while the second and fourth ones lacked TDZ pre-treatment followed by non-addition or addition of 4 μM TDZ in the SIM. Axillary meristem explants produced the best results with seed pre-treatment using 20 μM TDZ without TDZ in SIM and showed the highest rate of regeneration efficiency (71.33 ± 1.5%) after 20 days. Concurrently, plumular apex explants from TDZ-primed seeds was ranked second, exhibiting a regeneration percentage of 54.33 ± 2.3% in SIM without supplementation of TDZ, whereas explants from hypocotyls generated from seeds subjected to any of the TDZ treatments were not regenerated on any SIMs after 20 days.
Objectives The anti-inflammatory activity of Boswellia serrata extracts (BSE) is well known. BSE comprises boswellic acids (BA) such as 3- O -acetyl-11-keto- beta -boswellic acid (AKBA) and 11- keto -boswellic acid (KBA) as major constituents. One of the limitations of BAs is their poor oral bioavailability. The aim of the study was to prepare solid lipid particles of Boswellia serrata extract (SLBSP) to enhance the bioavailability of BAs. Methods The pharmacokinetic profile of BAs was studied in 10 healthy human volunteers following a single oral dose of 333 mg of SLBSP. Pharmacokinetic blood samples were collected at 0.5, 1, 1.5, 2, 2.5, 3, 4, 5, 6, 8, and 12 h post drug administration. Plasma KBA and AKBA levels were measured using a validated LC-MS/MS method. Pharmacokinetics parameters were estimated using Pheonix WinNonlin (Build 6.4.0.768) software. Results Ten healthy human volunteers were included and peak plasma concentration was achieved in 1.5 and 2.3 h for AKBA and KBA respectively. Maximum plasma concentration ( C max ) was 8.04 ± 1.67 ng/mL for AKBA and 23.83 ± 4.41 ng/mL for KBA whereas the corresponding area under the concentration-time curve (AUC) was 136.7 ± 56.77 ng/mL*h and 165.7 ± 24.5 ng/mL*h respectively. The elimination half-life ( t 1/2 ) of AKBA and KBA was 6.8 ± 3.0 h and 2.45 ± 0.3 h respectively. Conclusions The SLBSP formulation of BSE showed enhanced oral bioavailability of BAs compared with historically reported data of unformulated BSE.
In this recommendation, liver incurable record is investigated for structure gathering replica to foresee liver disorder. This proposal actualized a component replica development and near investigation for refining the forecast exactness of Indian liver incurable in three stages. In the primary stage, the min-max standardization calculation is put into the unique liver incurable record accumulated from the UCI document. In liver incurable conjecture the second stage, by the use of PSO characteristic decision, a portion of the liver incurable record from the sum normalized liver incurable record is gained which includes simply enormous impute. In the third stage, portrayal figuring’s are applied to the educational list. In this paper, an introduction evaluation between various estimation: Random Trees, Neural Network, eXtreme Gradient Boosting, Support Vector Machine (SVM), C5.0. The rule objective is to survey the rightness in social affair information concerning the benefit and plausibility of every calculation with respect to the accuracy, precision, affectability, and unequivocally. Exploratory outcomes show that the Neural Network gives the most fundamental accuracy (93.48 %.) with the least blunder rate. All assessments are executed inside a redirection environment and drove in SPSS information mining device.
Salinization is a worldwide environmental problem, which is negatively impacting crop yield and thus posing a threat to the world’s food security. Considering the rising threat of salinity, it is need of time, to understand the salt tolerant mechanism in plants and find avenues for the development of salinity resistant plants. Several plants tolerate salinity in a different manner, thereby halophytes and glycophytes evolved altered mechanisms to counter the stress. Therefore, in this review article, physiological, metabolic, and molecular aspects of the plant adaptation to salt stress have been discussed. The conventional breeding techniques for developing salt tolerant plants has not been much successful, due to its multigenic trait. The inflow of data from plant sequencing projects and annotation of genes led to the identification of many putative genes having a role in salt stress. The bioinformatics tools provided preliminary information and were helpful for making salt stress-specific databases. The microRNA identification and characterization led to unraveling the finer intricacies of the network. The transgenic approach finally paved a way for overexpressing some important genes viz. DREB, MYB, COMT, SOS, PKE, NHX, etc. conferred salt stress tolerance. In this review, we tried to show the effect of salinity on plants, considering ion homeostasis, antioxidant defense response, proteins involved, possible utilization of transgenic plants, and bioinformatics for coping with this stress factor. An overview of previous studies related to salt stress is presented in order to assist researchers in providing a potential solution for this increasing environmental threat.
Using the hydrodynamic model of semiconductor plasmas and coupled mode theory of interacting waves, we develop a theoretical formulation followed by numerical analysis to study parametric oscillation of acoustical phonon mode in magnetized doped III–V semiconductors. The origin of nonlinear interaction is assumed to lie in effective second-order optical susceptibility (χ(2)) arising due to nonlinear induced current density and acousto-optic polarization of the semiconductor medium. Expressions are obtained for threshold pump intensity (I0,th) and operational characteristics such as conversion efficiency (ηk) and single pass signal power gain (gsp) of the proposed single resonant optical parametric oscillator. Numerical analysis is made for a representative n-InSb crystal irradiated by 10.6 µm pulsed CO2 laser. The effects of some important parameters including external magnetic field (B0), mirror reflectivity (R), crystal length (L), etc. on I0,th, ηk and gsp of the single resonant optical parametric oscillator are analyzed in detail. The analysis establishes the technological potentiality of magnetized doped III–V semiconductors as the hosts for fabrication of highly efficient and widely tunable single-resonant optical parametric oscillators.
In this paper, we are using Dynamic key dependent AES algorithm and standard AES (Advanced Encryption Standards) to encrypt and decrypt audio file. To analysis the quality of algorithms both algorithms are successfully tested using histogram analysis, peak signal to noise ratio (PSNR), correlation analysis and entropy.
AISI 304 stainless steel categorized under austenitic, has good resistance to corrosion and applicable for high resistance to pitting and stresses. But it has poor hardness, sterngth and resistance to wear. In order to overcome the above problem, various hardening techniques like nitriding, carburizing, carbonitriding, Cyaniding etc are preferred. In this work, aqueous soluted nitriding process is carried out to improve the surface hardness and wear resistance on AISI 304 specimens. Three specimens in cylindrical shape with a diameter of 10mm and length 35mm are treated with salt bath nitriding process for a time period of 45 minutes, 90 minutes, 120 minutes and named as SBN 1, SBN 2, SBN 3 respectively. One specimen is kept untreated to compare the results with treated specimens. After the heat treatment procedure is completed, pin on disc wear testing instrument was used to conduct a wear test at a constant speed and load. All the specimens were subjected to Scanning Electron Microscope test and the results were compared.
In industries, components must operate under extreme conditions such as high load, speed, temperature and chemical environment. Materials are selected according to commercial availability, cost and their properties such as strength, hardness, etc. AISI 904L is a high-alloy stainless steel with low carbon content, poor surface hardness and wear characteristics. Many engineering failures are caused by fatigue, corrosion, and poor wear resistance, begins at the surface level. This causes cracks in the surface, reducing the material’s life. The surfaces of the materials were subjected to severe thermal, chemical, and shock loads. The selected AISI 904L materials for this work were subjected to gas nitriding process and processed with 3 different time parameters such as 12 hours, 18 hours and 24 hours respectively and named as GN1, GN2 and GN3. The treatments were done at a constant temperature of 650°C. Gas nitriding, in comparison to other nitriding processes such as plasma and liquid nitriding, provides good dimensional stability, reduced deformation, and uniform case depth regardless of the size and shape of the specimen. To analyze the wear properties, a pin on a disc machine is used. Finally, metallographic studies were performed by scanning electron microscopy.
Background Curcumin, quercetin and rutin are flavonoids having strong antioxidant potential, individually used in treatment of numerous ailments. The safety assessment of each of them is already established but no toxicological assessment has been done that would guarantee the safe use of these three flavonoids when used as a polyherbal combination (PHC). The aim of this study to evaluate the possible toxicological effect of polyherbal combination of these three flavonoids in female Swiss albino mice. Methods In acute toxicity study, the oral dose of poly herbal combination was administered to four groups stepwise in single dose and general behaviour, adverse effects and mortality were determined up to 14 days and compared to normal group. In sub-acute study, the tested poly herbal combination was administered orally for 28 days to the four experimental groups and their body weight was measured each alternate day from the first day of dosing. On 29th day the final body weight was recorded and euthanized by using thiopentone sodium, blood was collected and later haematological, lipid profile, biochemical parameter was evaluated and compared to normal group. Result In acute toxicity study, no abnormal general behaviour, adverse effects were reported. No significant changes were reported in body weight, haematological, lipid profile, biochemical parameter in sub-acute toxicity study. No mortality was reported in both the study. Histopathological examination revealed no alterations in clinical signs or organ weight at any dose. Conclusion The result concludes that the oral administration of Polyherbal combination did not produce any significant toxic effect in swiss albino mice. Hence, the Polyherbal combination can be utilized safely for therapeutic use.
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64 members
Neeraj Kumar Sharma
  • Business Administration
Bhanu Shrivastava
  • Administration
Zakir Hussain Khanday
  • Department of Life Science
Rajendra Man Banepali
  • School of Computer Science
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Jhunjhunūn, India