Shiraz University of Medical Sciences
Recent publications
Intra-individual variability of steady-state evoked potentials (ssEPs) is correlated with attention fluctuations and reveals the participant’s ability to sustain attention. We previously presented an analytical method to measure the variation of discrete Fourier measurements at the frequency of interest extracted from ssEP data and to model the Fourier estimates on the two-dimensional complex plane with an ellipse. In this paper, we will introduce the ratio of the major to minor axes of the ellipse, which we call the Length-to-Width Ratio (LWR), as an index of individual ability to control attention and show how to calculate the confidence interval of the LWR to be able to compare the LWR between conditions within a participant as well as between participants within or between studies. The method will enable us to find out the most sensitive electroencephalography electrode to attention fluctuation, to explore the neural correlates of attention, to differentiate cases with inconsistent control of attention from normal participants, and to objectively monitor the effects of therapeutic interventions on attention.
Trastuzumab (TZ) multifunctional Fe3O4 coated gold nanoparticles (Au NPs) through polyethylene glycol (PEG) linking for targeted molecular computed tomography (CT) imaging was developed. The prepared TZ-PEG-Fe3O4@Au NPs were fully characterized and cytocompatibility, X-ray attenuation measurement, and in vitro cell targeting ability were analyzed. The findings showed that the synthesized NPs, with a size of less than 100 nm, were non-toxic at specific concentration ranges, and exhibit better X-ray attenuation intensity than iodine-based contrast agents at the same concentration. The created targeted NPs can be employed as a contrast agent for molecular targeted CT imaging of cancer cells expressing the human epidermal growth factor receptor 2 (HER-2).
Purpose This study was conducted to determine whether critically ill patients admitted to the intensive care unit (ICU) with sepsis and septic shock may benefit from extended infusion of ampicillin/sulbactam compared with those receiving intermittent infusion. Material and methods This randomized assessor-blinded clinical trial was conducted in the ICUs of Nemazee and Shahid Rajaee hospital, Shiraz, Iran, from August 2019 to August 2021. The participants randomly received 9 g Ampicillin/Sulbactam every 8 h by either extended (infused over 4 h) or intermittent (infused over 30 min) intravenous infusion if their estimated glomerular filtration rate based on Cockrorft-Gault formula was higher than 60 ml/min. Results Totally, 136 patients were enrolled and allocated to the intervention and control groups, each with 68 patients. Clinical cure was significantly higher in the extended group (P = 0.039), but ICU and hospital length of stay did not differ between the groups (P = 0.87 and 0.83, respectively). The ICU (P = 0.031) and hospital (P = 0.037) mortality rates in the extended infusion group were significantly lower than those in the intermittent infusion group. Conclusion These data should be replicated in larger clinical trials before providing any recommendation in favor of this method of administration in clinical practice.
To manage accidents in actual conditions, we need to evaluate different accident scenarios on nuclear power plants. Removing the residual heat from the reactor core after the loss of off-site power (LOOP) accident and Station black-out (SBO) accident is one of the biggest challenges in such an incident. In this paper, LOOP and SBO Accidents with the main steam line break (MSLB) accident of No. 2 (inside the Containment) have been simulated by the thermal-hydraulic RELAP5 code on the VVER-1000/v446 reactor. A total of 5 different scenarios have been simulated, assuming the most difficult conservative conditions, and the results reveal the critical role of diesel generators in supplying emergency feed water pumps (EFWP), as well as the part of operator performance in securing a nuclear power plant in the condition of an accident. In the case of using a series of operator operations and using the water resources of the Deaerator tank on the secondary side with the Feed and Bleed system on the primary side, in The most brutal conservative mode (MSLB + SBO accident) by injecting the water into the steam generator-4, the temperature and pressure of the coolant in the primary side are reduced and by absorbing more heat from the reactor, core melting is delayed about 25,000 s, and the safety of Bushehr nuclear power plant (BNPP) against this accident will be improved.
Background Behçet's Disease (BD) is a chronic autoimmune disease with unknown etiology. Adipokines due to their roles in the regulation of immune responses might be important in the induction and progression of BD. Subjects and methods This case-control study included 340 patients with BD and 310 healthy controls. Single nucleotide polymorphisms (SNPs) in adiponectin (rs266729 and rs1501299) and leptin (rs7799039 and rs2167270) genes were determined using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and serum levels of adipokines were measured using enzyme-linked immunosorbent assay (ELISA). Results A higher frequency of leptin rs7799039 GG, AG, and AG +GG genotypes and G allele was revealed in patients. Besides, patients had more leptin rs2167270 AG and AG +AA genotypes and A allele. Furthermore, rs2167270 AA genotype and A allele were more frequently seen in total and female patients who had genital aphthous. Patients had significantly more serum levels of adiponectin while those with genital aphthous had significantly more leptin levels. No significant association was observed between genotypes and alleles of adiponectin SNPs and BD. Conclusion Our findings indicated that leptin gene polymorphisms might predispose Iranian individuals to BD. Besides, elevated serum levels of adiponectin might facilitate BD pathogenesis.
Background The higher hospitalisation rates of those aged 0–19 years (referred to herein as ‘children’) observed since the emergence of the immune-evasive SARS-CoV-2 Omicron variant and subvariants, along with the persisting vaccination disparities highlighted a need for in-depth knowledge of SARS-CoV-2 sero-epidemiology in children. Here, we conducted this systematic review to assess SARS-CoV-2 seroprevalence and determinants in children worldwide. Methods In this systematic review and meta-analysis study, we searched international and preprinted scientific databases from December 1, 2019 to July 10, 2022. Pooled seroprevalences were estimated according to World Health Organization (WHO) regions (at 95% confidence intervals, CIs) using random-effects meta-analyses. Associations with SARS-CoV-2 seroprevalence and sources of heterogeneity were investigated using sub-group and meta-regression analyses. The protocol used in this study has been registered in PROSPERO (CRD42022350833). Findings We included 247 studies involving 757,075 children from 70 countries. Seroprevalence estimates varied from 7.3% (5.8–9.1%) in the first wave of the COVID-19 pandemic to 37.6% (18.1–59.4%) in the fifth wave and 56.6% (52.8–60.5%) in the sixth wave. The highest seroprevalences in different pandemic waves were estimated for South-East Asia (17.9–81.8%) and African (17.2–66.1%) regions; while the lowest seroprevalence was estimated for the Western Pacific region (0.01–1.01%). Seroprevalence estimates were higher in children at older ages, in those living in underprivileged countries or regions, and in those of minority ethnic backgrounds. Interpretation Our findings indicate that, by the end of 2021 and before the Omicron wave, around 50–70% of children globally were still susceptible to SARS-CoV-2 infection, clearly emphasising the need for more effective vaccines and better vaccination coverage among children and adolescents, particularly in developing countries and minority ethnic groups. Funding None.
Iran's most important iron ore mine is located in the central region, and because of the water shortage in this area, the need to reuse the effluent from this mine is essential. On the other hand, there are no suitable conditions for treating large effluent volumes in iron mine in central Iran. For this reason, produced effluent should be reduced and returned to the consumption cycle by using appropriate technology. This study aimed to investigate the ozonation/lime effect on polymer consumption reduction and evaluate the treatment and economic efficiency compared to the currently used treatment method (coagulation-flocculation without ozonation/lime). The use of ozonation along with the coagulation and flocculation process has been an effective factor in reducing all the studied indicators, which has been a much more significant reduction effect for turbidity (95%), decreasing from 374-350NTU in the non-ozonation process to 110-160NTU, and Chemical oxygen demand (37%). In addition to increasing the treatment efficiency, the hybrid ozonation/coagulation and flocculation process reduced operation costs. The ozonation process caused the high-level conversion of Fe ²⁺ and Al ²⁺ to Fe ³⁺ and Al ³⁺ (> 90%), thus it improved wastewater treatment and increased cost benefit. The hybrid process was affected in improving the effluent quality and reducing the produced sludge volume. The ozonation process caused sludge volume reduction or has photocatalytic effect on it. It effected the micro-sized bubbles production reduction in sludge volume unit. However, estimating the cost–benefit of using this method can be beneficial in making the final decision on whether to use it or not.
Objectives: The purpose of the current study was to apply Two-step cluster analysis on a large dataset of patients with juvenile myoclonic epilepsy (JME). We hypothesized that there are distinct subgroups of patients with similar clinical characteristics. We also hypothesized that the seizure outcome is different between these clusters. Methods: This was a retrospective study of a prospectively developed database. All patients with a diagnosis of JME were studied at the epilepsy center at Shiraz University of Medical Sciences, Shiraz, Iran, from 2008 until 2022. The Two-Step cluster analysis (Schwarz's Bayesian Criterion) was applied to the whole dataset. In the next step, the seizure outcome was compared between the clusters of patients. Results: Two hundred and ninety-five patients were included. Two-Step cluster analysis showed that there were two distinct clusters of homogeneous subgroups of patients with JME, presenting with more or less similar clinical characteristics, with a fair (0.4) silhouette measure of cohesion and separation. One hundred and eighty-one patients had a follow up duration of 12 months or longer at our center. Response to treatment at 12 months of follow-up was different between the clusters (as a trend): 43 patients (39.1%) from cluster 1 and 18 people (25.4%) from cluster 2 were free of all seizure types (p = 0.076). Conclusion: The Two-Step cluster analysis identified two distinct clusters of patients with JME. Individuals with JME, who also have absence seizures, are less likely to enjoy a seizure free state with ASMs.
Purpose The relationship between the inflammatory and antioxidant potential of an athlete's diet and their oxidative biomarkers is an important area of investigation. Therefore, this study aimed to assess the excretion of 8-hydroxy-2-deoxyguanosine (8-OHdG) and F 2alpha -isoprostane (F 2a -IP) in the urine of male football players and healthy non-athlete controls. This study also aimed to examine the associations among the dietary inflammatory index (DII), the dietary total antioxidant capacity (DTAC), and the dietary phytochemical index (PI) with 8-OHdG and F 2a -IP. Methods In this descriptive-analytical study, 45 male football players and 45 healthy non-athletes, who were individually matched based on age and body mass index (BMI), were recruited from Shiraz City, Iran. Fasted urine samples were analyzed for 8-OHdG and F 2a -IP levels. Anthropometric measurements were performed, and body composition was assessed using a body composition analyzer. A valid food frequency questionnaire (FFQ) was used to calculate DII, DTAC, and PI scores. Data analysis was conducted using a generalized estimating equation (GEE) model. Results We found that 8-OHdG (β = −6.96), F 2a -IP (β = −82.58), and DII (β = −2.06) were significantly lower, while DTAC (β = 2.37) and PI (β = 0.084) were significantly higher in the football player group compared with the non-athlete group ( P < 0.001 for all variables). In all participants, dietary indices were significantly associated with oxidative biomarkers. DII was positively associated with 8-OHdG (β = 2.25; P < 0.001) and F 2a -IP (β = 38.34; P < 0.001). Furthermore, negative associations between DTAC (β = −1.42; P < 0.001) and PI (β = −35.37; P < 0.001) with 8-OHdG were found. Moreover, DTAC (β = −17.34; P < 0.001) and PI (β = −428.11; P = 0.003) were negatively associated with F 2a -IP. Conclusion The results of this study highlighted the importance of a healthy diet in reducing oxidative stress among football athletes. The levels of urinary biomarkers for DNA and lipid oxidation were found to be lower in football players compared to non-athletes. This suggests that following an anti-inflammatory and antioxidant-rich diet may help reduce oxidative stress in these individuals.
Objective Exercise and psychological stress can induce different effects on coagulation factors, however the effect of adaptation to different exercise training on acute response to stress has not been known yet. So, the purpose of present study was to evaluate the effect of an acute noise stress on the response of coagulation factors including prothrombin time (PT), partial thromboplastin time (PTT), and platelet count in adapted rats with two types of training.Materials and methodsMale Wistar rats were randomly divided into seven groups (6 number in each group) including: control (C), control time (CT), exposure to acute noise stress (S), high intensity interval training (HIIT), moderate intensity continuous training (MCT), HIIT followed by exposure to acute noise stress (HIIT + S), MCT followed by exposure to acute noise stress (MCT + S). Exercise groups (MCT, HIIT, MCT + S, HIIT + S) performed exercise training for 8 weeks. Noise stress groups (HIIT + S, MCT + S and S) were exposed to one session of noise stress. Blood samples were taken 48 h after the last session of exercise in HIIT and MCT and simultaneously in CT groups and immediately following noise stress in three stress groups. Blood sample of C group was taken at the beginning of the study.ResultsMCT increased PT at rest while its adaptation reduced PT response to noise stress. HIIT was not effective on variables at rest, while its adaptation reduced PTT and PT following noise stress.ConclusionHIIT is more appropriate exercise training mode compared to MCT because its adaptation reduced PT and PTT in response to noise stress.
The short-term therapeutic impacts of stem cells and their derivatives were frequently reported in preclinical investigations of ischemic stroke (IS); however, several drawbacks including accessibility, abundancy, and ethical concerns limited their clinical application. We describe here for the first time the therapeutic potential of human hair follicle-derived stem cells (hHFSCs) and their conditioned medium (CM) in a rat model of IS. Furthermore, we hypothesized that a combination of cell therapy with repeated CM administration might enhance the restorative efficiency of this approach compared to each treatment alone. Middle cerebral artery occlusion was performed for 30 min to induce IS. Immediately after reperfusion, hHFSCs were transplanted through the intra-arterial route and/or hHFSC-CM administered intranasally. The neurological outcomes, short-term spatial working memory, and infarct size were evaluated. Furthermore, relative expression of seven target genes in three categories of neuronal markers, synaptic markers, and angiogenic markers was assessed. The hHFSCs and hHFSC-CM treatments improved neurological impairments and reduced infarct size in the IS rats. Moreover, molecular data elucidated that IS was accompanied by attenuation in the expression of neuronal and synaptic markers in the evaluated brain regions and the interventions rescued these expression changes. Although there was no considerable difference between hHFSCs and hHFSC-CM treatments in the improvement of neurological function and decrement of infarct size, combination therapy was more effective to reduce infarction and elevation of target gene expression especially in the hippocampus. These findings highlight the curative potential of hHFSCs and their CM in a rat model of IS. Graphical Abstract
The challenge of being able to respond to student adjustment needs in elementary schools is a problem worldwide. In this manuscript, we offer one example from Indonesia. Using data from 15 public elementary schools from three small regions in Indonesia: Semarang, Surabaya, and Jakarta, we analyze conditions that result in neglect. Student neglect is any inappropriate action by an incompetent person that results in serious physical or emotional harm, or abuse, which presents a serious risk of harm to the student. The data were collected through documentation, interview, and observation. The study results showed no specific handling adjustment problems regulations and mechanisms, specialized professional staff handling adjustment, and specific room for handling adjustment problems within the public elementary school due to the unawareness, misunderstanding, ignorance, the less-caring educational system, and also the disconnection of the relationship between the educational institution and the community. The study suggests that student neglect on adjustment problems at public elementary schools should not be taken lightly because this can threaten the psychological condition of students in the future.
Objectives Hereditary fructose intolerance (HFI) is caused by aldolase B enzyme deficiency. There has been no report about HFI from Iran and the type of mutations has not been reported in the Iranian population so far. Case presentation Herein we report a 2 year old girl presented with failure to thrive, hepatomegaly, and liver dysfunction. The primary impression has been hepatic glycogen storage disease type 1 or 6. This diagnosis was not confirmed by laboratory data and liver biopsy. Therefore, targeted-gene sequencing (TGS) covering 450 genes involved in inborn errors in metabolic diseases was performed. The results of TGS showed a rare novel homozygous pathogenic variant c.944del (p.Gly315ValfsTer15) in the ALDOB gene. Conclusions This report introduces a novel variant that expands the mutational spectrum of the ALDOB gene in patients with HFI.
Background For the first time, we aimed to determine the epidemiology and associated factors of obesity and hypertension among children of military families in our region. Methods In this multi-centered study, children between the ages of 5 to 12 years old, entered the study. Data on baseline and clinical characteristics, history of disease and anthropometric measurements, were collected. Results Among 504 children, 44.2% were males. Mean (SD) age of participants was 7.9 ± 1.9 years. Overall, 5% were obese and 9.9% were overweight. In total, 16.3% had elevated BP, 12.5% had stage one and 0.2% had stage two hypertension. Age (beta = 0.306, OR = 1.35, 95% CI:1.14—1.61), obesity/overweight (OR = 5.58, 95% CI:2.59—12.0), history of hypertension in mother (OR = 43.24, 95% CI:5.99—312.11), low birth weight (OR = 7.96, 95% CI:2.59—12.0), physical activity (OR = 0.27, 95% CI:0.10—0.72), and consumption of fast food more than once a week (OR = 3.36, 95% CI:1.82—6.19), were associated with risk of hypertension. Furthermore, age (beta = 0.346, OR = 1.41, 95% CI:1.21—1.64), history of childhood obesity in the father (OR = 3.78, 95% CI: 1.77—8.06) and mother (OR = 2.44, 95% CI:1.07—5.56), and physical activity (OR = 0.27, 95% CI:0.11—0.66), were associated with obesity. Conclusion Age, obesity/overweight, history of hypertension in the mother, birth weight, physical activity, and consumption of fast food, were associated with risk of hypertension. Moreover, age, history of childhood obesity in parents, and physical activity, were associated with obesity. Furthermore, we found that school-age children in military families have higher rates of hypertension and overweight compared to other reports from our region.
Objective This study aimed to investigate the fracture resistance of one-piece screw-retained hybrid monolithic zirconia ceramic restorations in different implant angulations. Materials and methods Three implant fixtures were embedded in acrylic resin blocks with 0°, 15°, and 25° angulations. For each group of implant angulations, 11 screw-retained one-piece monolithic zirconia restorations were made and bonded to the titanium inserts with a dual-cure self-adhesive resin. The complexes were screwed to the implant fixtures with titanium screws. The samples were thermocycled, subjected to compressive load, and fracture modes were recorded. One-way ANOVA and post hoc Tukey’s test were used for statistical analyses (α = 0.05). Results One-way ANOVA showed the fracture resistance to be significanltly different among the study groups ( P = 0.036). The 15° group was significantly more resistant than 0° ( P = 0.031). However, the 25° group was not significantly different from the 15° ( P = 0.203) and 0° groups ( P = 0.624). Fractures occurred only on the restorations, not at the screw levels. Conclusions Tilting the implant up to 15° improves the fracture resistance of one-piece screw-retained hybrid monolithic zirconia restorations; however, increasing the tilt to 25° would not yield restorations with significantly better fracture strength than the straight implants. Accordingly, when angulated implants are indicated in the esthetic zones, one-piece screw-retained hybrid monolithic zirconia ceramic restorations can be used with acceptable fracture strength.
Introduction: Cognitive emotion regulation (CER) strategies define as cognition-based responses according to emotion-eliciting experiences that can change the type and severity of individuals’ reactions and behaviors. This modification may positively or negatively affect cognitive performance and therefore, it is a defining issue in the workplace. Notably, industries such as combined cycle power plants need to hire staff with a high cognitive ability to perform their duties in a highly efficient way. Since CER is of great importance for overall health and cognitive performance, we aimed to evaluate the state of CER among control room operators (CROs) in the Fars combined cycle power plant. Material and Methods: The CER questionnaire (CERQ) measures nine cognitive coping strategies (i.e., self-blame, other-blame, rumination, catastrophizing, positive refocusing, planning, positive reappraisal, putting into perspective, and acceptance) that are followed when an individual confronts negative events. The CERQ (short version) was administered to 57 male CROs at the Fars combined cycle power plant. The questionnaire also collected demographic data. Statistical analyses were performed using SPSS Version 25.0. For the normality test, Shapiro-Wilk was the method of choice. Results: Results of the CERQ scoring showed that the median with interquartile range (IQR) in appropriate and inappropriate categories were 3.50 (3.30-4.00) and 2.62 (2.25-3.06), respectively. Of note, age (39.07 ±6.19) and work experience (14.49±6.26) were not significantly correlated with the results of CERQ. Conclusion: Taken together, adaptive cognitive strategies (acceptance, positive refocusing, planning, positive reappraisal, and putting into perspective) were reported to be used more often than less adaptive strategies. In general, staff strategies were appropriate while facing a negative event. Although assessing CER in high-demand workplaces is necessary, factors such as managerial styles, job engagement, job satisfaction, and larger sample size should be further studied.
This study aimed to model the dispersion of emitted SO2 from stacks and flares in one of the largest Gas Refinery Companies in the Middle East . Pollutant emission coefficients and air pollution’s various sources contributions were determined based on the collected data after measuring SO2 concentrations in a fixed monitoring station (stack) and across different distances from it for a year. The SO2 release pattern was simulated, and annual pollutant concentrations in average periods of 1-hr and 24-hr were predicted using AERMOD 8.9.0. The maximum simulated ambient SO2 were 27,447 and 4592 µg/m³ in average sampling times of 1-hr and 24-hr, respectively. The hazard quotient of 95% percentile for children, teenagers, and adults due to inhalation of SO2 was more than one.The maximum concentration of SO2 in the 1-hour and 24-hour period in the study area was higher than the amount introduced by Iran’s clean air standard and the WHO standard.
Ischemic stroke is the major form of stroke with two separate vascular territories. Many risk factors are related to stroke outcomes in both territories. The present descriptive research was carried out on the basis of data obtained from the Safe Implementation of Treatments in Stroke (SITS) registry on Iranian intravenous thrombolysis ischemic stroke cases. Vascular territory involved in each case and three-month excellent outcome, functional independence, mortality rate, and brain hemorrhage occurrence were determined. Univariable and multivariable logistics regression analyses were utilized in order to investigate association of ischemic stroke outcomes with the vascular territory involved and other related factors. Among 1566 patients 95.4% was anterior circulation stroke patients and 4.6% was posterior circulation stroke cases. There is no significant association between vascular territory with mortality (OR of PCS vs ACS: 0.74, 95% CI 0.37–1.46), excellent functional outcome (OR 0.72, 95% CI 0.44–1.19), functional outcome (OR 0.86, 95% CI 0.52–1.42) and local hemorrhage (OR 0.98, 95% CI 0.30–3.21). Among major risk factors, age, diabetes, NIHSS score and admission duration, increased significantly odds of three-month mortality, excellent outcome, and functional independence in the multivariate analysis. The highest of odds was in NIHSS score with a dose–response association. The vascular territory was not an outcome predictor in ischemic strokes. The most important predictor was baseline NIHSS.
Background The association between breast cancer (BC) and different indices of dietary fats has not been well-studied. Thus, this study aimed to investigate the association between BC and dietary fat quality (DFQ) indices in Iranian women. Methods This case–control study was conducted on 120 women with breast cancer and 240 healthy women in Tehran, Iran. Food Frequency Questionnaire and nutritionist IV software were used to assess the intake of dietary fats and to calculate the DFQ indices. Results The patients with BC had a higher total fat (TF) ( P < 0.01) and a lower ratio of polyunsaturated fatty acids (PUFAs) omega-3 to PUFAs omega-6 (ω-3/ω-6) compared with the controls ( P < 0.001). TF had a significant association with BC risk (OR: 1.16; 95% CI: 1.01–1.33, P < 0.001). No significant association was found between BC and PUFA/saturated fatty acid ratio or the ω-3/ω-6 ratio. Conclusion The patients with BC had a lower ω-3/ω-6 ratio and a higher total dietary fat intake than the healthy women. Total dietary fat intake was also directly associated with the risk of BC. Thus, low-fat diets may have beneficial effects for BC prevention. Further longitudinal studies are warranted.
Aims In this study, the chitosan-based nanogels, which were synthesized by the ionic gelation method were used for solid-phase microextraction of methotrexate Background Today, successful drug extraction, especially in biological fluids, due to interfering factors and the trace level of targeted analytics, faces many challenges in a complex matrix. Therefore, providing a suitable and sensitive method that can be increased the efficacy of extraction method has been considered. Objective In this study, the chitosan-based nanogels, which were synthesized by the ionic gelation method were used for solid-phase microextraction of methotrexate Method The in vitro characterization of nanogels were performed by evaluation of morphological characteristics with TEM, determination of particle size, PDI, and zeta potential and also the HPLC assay method for determination of methotrexate concentration in different media and determination of extraction yield Result The nanogels with the average size of 135.6 nm and PDI of 0.14 were used for nanoextraction of methotrexate in this study. The concentration of methotrexate, amount of nanogel, and time of extraction were evaluated as an essential factor affecting the extraction yield. Conclusion Finally, the result of the recovery of 75% and 69% in aqueous and plasma media demonstrated that nanogel could be a promising and reliable method for bioanalysis of drugs in different media. It seems that the use of nanogels can be an excellent way to extract methotrexate from biological environments Other non
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3,411 members
Kurosh Kalantar
  • Department of Immunology
Fariborz Ghaffarpasand
  • Department of Neurosurgery
Mehdi Salehipour
  • Department of urology
Zand Avenue, 7134845794, Shiraz, Fars, Iran
Head of institution
Prof. Mohammad reza Lotfi