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    ABSTRACT: Background: Chronic rejection leading to allograft loss remains a significant concern after facial allotransplantation. Chronic rejection may occur without clinical signs or symptoms. The current means of monitoring is histologic analyses of allograft biopsy specimens, which is both invasive and impractical. Prior data suggest that chronic rejection is associated with changes in intima and media thickness of vessels in arms and solid organ allografts; such data have not been published for face transplant recipients. Methods: The authors used a 48-MHz transducer to acquire images of the bilateral facial, radial, dorsalis pedis and, if applicable, sentinel flap arteries in five face transplant recipients (8 months to 4.5 years after transplantation) and five control subjects. The authors assessed the intima, media, and adventitia thickness plus lumen and the total vessel diameter and area. Results: Face transplant recipients had thicker intima in all sites compared with controls, but the ratio of the intimal thickness of facial and radial arteries was similar in face transplant recipients compared with controls (1.00 versus 0.95; p = 0.742). Intraobserver correlation showed reliable reproducibility of the measurements (r = 0.935, p ≤ 0.001). Interobserver correlation demonstrated reproducibility of intima measurements (r = 0.422, p ≤ 0.001). Conclusion: The authors demonstrate that ultrasound biomicroscopy is feasible for postsurgical monitoring, and have developed a new benchmark parameter, the facial artery-to-radial artery intimal thickness ratio, to be used in future testing in the setting of chronic rejection. Clinical question/level of evidence: Diagnostic, IV.
    No preview · Article · Oct 2015 · Plastic and Reconstructive Surgery
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    ABSTRACT: The usage of graphical representations of work and business process such as process models can be considered a common practice in modern organizations. As their development can become a complex task it is reasonable to draft them collaboratively. Also they become increasingly useful when used by larger groups throughout an organization. However despite modeling being a popular approach in practice, models are hardly used by non-experts and have little impact on the people actually working in these processes. This raises questions such as why there is so little use of models after their creation, how this usage can be increased and which kind of tools and modes of interaction are suitable for non-modeling experts. Furthermore as collaborative modeling most of the time remains restricted to collocated facilitated workshops. This approach however is not feasible as processes have to be rapidly adjusted to changing conditions inside and outside of an organization. So given the increasing usage of graphical representations in organizations, their collaborative use and creation is of vital interest for the CSCW community and therefore this workshop can be a starting point in forming a community for research in this area.
    Full-text · Article · Oct 2015
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    ABSTRACT: Daily stressors, compared to traumatic events, are increasingly recognized as important risk factors for mental health. The role of general self-efficacy on the relationship between daily stress and aspects of mental health has not yet been examined. Taking into account the dual factor model of mental health, which postulates that mental health is more than the absence of psychopathological symptoms, we tested mediation effects of self-efficacy separately for positive and negative mental health. Total, direct and indirect effects were estimated using data from a large nationally representative German population sample (N = 1,031) by bootstrapped mediation analyses providing 95% bias corrected bootstrap confidence intervals. Results indicated self-efficacy as a mediator of the effects of daily stressors on mental health, with superior effect sizes for positive compared to negative mental health. Mediation effects were replicated in student samples from Germany (N=394), Russia (N=604) and China (N=8,669). Findings suggest that self-efficacy operates as a buffer of daily stress. However, a full mediation model was not supported as multiple psychological resources can have protective effects. This study provides the first transnational evidence for different stress-buffer effects for the two dimensions of mental health.
    Full-text · Article · Oct 2015 · International Journal of Clinical and Health Psychology


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Autophagy 01/2016; 12(1):1-222. DOI:10.1080/15548627.2015.1100356
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