Osnabrück University

Anionic microporous polymer networks are prepared from a fluorinated tetraarylborate precursor via the Yamamoto reaction. The charge density can be continuously varied by adjusting the ratio of a neutral tetraphenylmethane comonomer. The obtained polymer networks are stable under ambient conditions and exhibit a surface area of up to 1500 m2 g‐1. Cationic molecular complexes can be embedded in the anionic network by simple ion exchange, making them viable for gas phase catalytic reactions. In this case, the cationic complex of the Crabtree’s catalyst is introduced to prepare a solid material for the gas phase hydrogenation of ethylene to ethane at room temperature.

Background Since its inception in 1980, the MOHL index (% patients who are male, have occupational, hand, or leg dermatitis, respectively) and its later evolutions until the presently used MOAHLFA(P) index (adding % patients with atopic dermatitis, face dermatitis, age 40+ years and positive reaction(s) to ≥ 1 baseline series allergen) have been intended to convey important demographic and clinical information on the patients patch tested in a certain area and time, aiding the interpretation of the observed spectrum of sensitisation. Objectives To examine the current usage of the MOAHLFA(P) index and suggest consolidated definitions for its single items. Methods A title/abstract search in Medline identified publications mentioning the evolving acronyms. A Delphi‐like survey among contact dermatitis experts collected agreement with suggested definitions. Results The search term ‘MOAHLFA’ was used in 35 publications from a broad geographical origin. More than 80% of the 24 participants of the survey (65% response) agreed on maintaining to use (i) sex for the ‘M’ criterion, (ii) occupation‐related dermatitis irrespective of medicolegal definitions for the ‘O’, (iii) atopic dermatitis (but not rhinitis or asthma) for the ‘A’. The possibility to use more than one site among ‘H’, ‘L’ and ‘F’ and a more detailed description of age distribution were favoured, and the difficult interpretability of the ‘P’ measure was highlighted. Conclusions The ‘classical’ MOAHLFA(P) index may be extended. Some aspects, notably atopic dermatitis, need further standardisation.

This study examines how Climate-Related Financial Policies (CRFPs) support decarbonization and renewable energy transitions across 87 countries from 2000 to 2023. Using the Policy Sequencing Score (PSS) and a bindingness-weighted adoption indicator, it explores the relationships between CRFPs, CO2 emissions, and Renewable Energy Production (REP) across diverse economic and institutional contexts. Findings reveal significant variation in outcomes. Advanced economies and OECD countries leverage structured policies and robust institutions to achieve steady emissions reductions and REP growth, with diminishing returns at higher policy intensities. Emerging Markets and Developing Economies (EMDEs) face institutional and structural constraints but show strong responsiveness to targeted policies, particularly in Sub-Saharan Africa and South Asia, where renewable energy growth potential is notable. Regions such as Latin America and East Asia display mixed trends, reflecting unique challenges and opportunities. Binding policies prove essential for environmental outcomes, particularly in institutionalized settings, while EMDEs require capacity building and international cooperation to address barriers. This study highlights the importance of tailoring CRFPs to specific contexts, emphasizing policy sequencing, enforcement, and capacity building. By identifying global and regional variations, the findings provide actionable insights for aligning financial systems with climate goals, fostering a sustainable low-carbon transition, and addressing equity challenges.

How populations adapt to their environment is a fundamental question in biology. Yet, we know surprisingly little about this process, especially for endangered species, such as nonhuman great apes. Chimpanzees, our closest living relatives, are particularly notable because they inhabit diverse habitats, from rainforest to woodland-savannah. Whether genetic adaptation facilitates such habitat diversity remains unknown, despite it having wide implications for evolutionary biology and conservation. By using newly sequenced exomes from 828 wild chimpanzees (388 postfiltering), we found evidence of fine-scale genetic adaptation to habitat, with signatures of positive selection in forest chimpanzees in the same genes underlying adaptation to malaria in humans. This work demonstrates the power of noninvasive samples to reveal genetic adaptations in endangered populations and highlights the importance of adaptive genetic diversity for chimpanzees.

Assessing cognitive demand is crucial for research on self-regulated learning; however, discrepancies in translating essential concepts across languages can hinder the comparison of research findings. Different languages often emphasize various components and interpret certain constructs differently. This paper aims to develop a translingual set of items distinguishing between intentionally invested mental effort and passively perceived mental load as key differentiations of cognitive demand in a broad range of learning situations, as they occur in self-regulated learning. Using a mixed-methods approach, we evaluated the content, criterion, convergent, and incremental validity of this scale in different languages. To establish content validity, we conducted qualitative interviews with bilingual participants who discussed their understanding of mental effort and load. These participants translated and back-translated established and new items from the cognitive-demand literature into English, Dutch, Spanish, German, Chinese, and French. To establish criterion validity, we conducted preregistered experiments using the English, Chinese, and German versions of the scale. Within those experiments, we validated the translated items using established demand manipulations from the cognitive load literature with first-language participants. In a within-subjects design with eight measurements (N = 131), we demonstrated the scale’s criterion validity by showing sensitivity to differences in task complexity, extraneous load manipulation, and motivation for complex tasks. We found evidence for convergent and incremental validity shown by medium-size correlations with established cognitive load measures. We offer a set of translated and validated items as a common foundation for translingual research. As best practice, we recommend four items within a reference point evaluation.

Compartmentalized models with coupled catalytic networks are considered as "protocells" in the context of research related to the origin of life. To model the kinetics of a simple cellular uptake‐metabolism process, we use a compartmentalized protocell system that combines liposome‐encapsulated intravesicular reporter pairs with co‐encapsulated enzymes to monitor the membrane transport of a substrate (analyte uptake) and its subsequent enzymatic reaction inside the vesicles (metabolism to the product). The intravesicular chemosensing ensembles consist of the macrocycles cucurbit[7]uril or p‐sulfonatocalix[4]arene and matching fluorescent dyes to set up suitable reporter pairs. When these macrocycle/dye reporter pairs are co‐encapsulated with enzymes (trypsin, protein kinase A, or butyrylcholinesterase), it is possible to monitor first the transport of different substrates (polylysine, protamine, H‐LRRWSLG‐OH, or butyrylcholine) through added pores (outer membrane proteins F and C), with synthetic carriers (amphiphilic calixarenes), or by direct permeation (only for butyrylcholine). The subsequent enzymatic conversions of the substrates after they have entered the corresponding protocells can be monitored as consecutive reactions. The new type of in vitro assays can be applied to different enzymes and analytes, affording a comprehensive chemosensing system of high chemical complexity.

Compartmentalized models with coupled catalytic networks are considered as "protocells" in the context of research related to the origin of life. To model the kinetics of a simple cellular uptake‐metabolism process, we use a compartmentalized protocell system that combines liposome‐encapsulated intravesicular reporter pairs with co‐encapsulated enzymes to monitor the membrane transport of a substrate (analyte uptake) and its subsequent enzymatic reaction inside the vesicles (metabolism to the product). The intravesicular chemosensing ensembles consist of the macrocycles cucurbit[7]uril or p‐sulfonatocalix[4]arene and matching fluorescent dyes to set up suitable reporter pairs. When these macrocycle/dye reporter pairs are co‐encapsulated with enzymes (trypsin, protein kinase A, or butyrylcholinesterase), it is possible to monitor first the transport of different substrates (polylysine, protamine, H‐LRRWSLG‐OH, or butyrylcholine) through added pores (outer membrane proteins F and C), with synthetic carriers (amphiphilic calixarenes), or by direct permeation (only for butyrylcholine). The subsequent enzymatic conversions of the substrates after they have entered the corresponding protocells can be monitored as consecutive reactions. The new type of in vitro assays can be applied to different enzymes and analytes, affording a comprehensive chemosensing system of high chemical complexity.

The organism is the central entity in biological science. However, consensus with regard to the definition of the underlying concept is lacking. Moreover, several ambiguous life forms exist that challenge current definitions of the term. Based on a comprehensive analysis of the available literature, we provide an overview of the criteria and approaches that have been previously used to define organismality. In addition, we highlight non-paradigmatic biological entities to identify problems that challenge definitions of organismal units. To address these issues, we propose a cross-disciplinary definition of the organism concept and provide a list of key criteria that allow both paradigmatic and non-paradigmatic cases to be unequivocally classified. In this way, our work not only provides newcomers with an overview of this exciting field, but also enhances communication across disciplines.

Background The national health record (ePA) was introduced January 1st, 2021 in Germany and is available to every person insured under statutory health insurance. This study investigated the acceptance and expectations of the national health record in Germany, focusing on consumer perspectives, expectations, barriers, information needs, and communication aspects. Methods An exploratory, observational, cross-sectional online survey was conducted one year after ePA introduction, followed by descriptive statistical analysis. Results The top three ePA use cases were medical document collection, simplified data exchange between medical institutions, and emergency medical information. Adoption barriers included lack of information and access, privacy concerns, and perceived lack of necessity. Participants that felt informed about the ePA, reported they received information primarily from health insurances, the media, and educational or professional sources, mainly through printed brochures, social media, or via emails. Most participants (86.5%) preferred being informed through conversations, particularly with health insurance providers (81.5%) and doctors (61.0%). Written information was highly desired (94.5%), preferably via email or information letters/flyers. However, more than half of the participants (55.6%) reported being uninformed about the ePA introduction. Conclusion The study revealed a communication gap between providers and consumers, leading to a low acceptance rate of digital health technologies. Comparisons with other countries showed low adoption rates for opt-in systems. The authors suggest changing communication strategies, given users prefer direct information from doctors or health insurance companies. Adopting an opt-out system with professional social media and marketing campaigns could increase nationwide ePA adoption.

This article analyses the phenomenon of anti-genderism from two different aspects: first, as a (meta-)political strategy elaborated by protagonists of the intellectual (extreme) New Right; second, following the studies of the Bielefeld Institute for Interdisciplinary Research on Conflict and Violence, as a conglomeration of elements of the syndrome of Group-Related Misanthropy (Heitmeyer 2002–2011; Zick and Küpper 2021). The first aspect focuses on the relatively small number of right-wing protagonists and activists for whom the topic of anti-genderism is an appropriate means to increase their radius of action and their degree of acceptance and effectiveness even within predominantly liberal and democratic societies and to establish worldwide networks (for example Datta 2020, 2021; Mascolo 2023). The second aspect focuses on the mostly unconscious human tendency to prejudice and implicit devaluations within societies—a psychological dynamic which becomes a ‘highly welcome’ means to protagonists of the extreme right in order to trigger negative emotions of anger and hatred. The two aspects complement each other, in so far as widespread prejudices and relatively well veiled authoritarian policy offers come together in the thematic area of anti-genderism and thus develop a special dynamic.

Situated affectivity investigates how natural, material, and social environmental structures, so-called ‘scaffolds,’ influence our affective life. Initially, the debate focused on user-resource-interactions, i.e., on cases where individuals (‘users’) actively structure the environment (‘resource’) in beneficial ways, setting up scaffolds that allow them to solve routine problems, modify their means of coping with challenges, or avail themselves of new affective competences. More recently, cases of mind invasion have captured philosophers’ attention where the ways others structure the environment affect, or invade, people’s minds, typically without their awareness and with harmful consequences. This paper contributes to recent discussions about the variety of phenomena that can count as ‘scaffolded affectivity’ in general and ‘scaffolded affective harm’ in particular. It also addresses the emerging question of how harmful affective scaffolds can come to have a grip on people’s minds, despite their detrimental consequences. We first disentangle some misconceptions and illustrate how diverse (harmful) affective scaffolds can be. In contrast to recent approaches that have characterized scaffolds in largely descriptive terms, we then identify factors that can help explain why a given scaffold is effective in modifying people’s minds. We also try to shed light on why some agents and some social structures are especially likely to experience or cause scaffolded affective harm, respectively, by arguing that user-resource-interactions and mind invasions are not independent, but intimately intertwined and mutually reinforcing, especially in the digital domain. We conclude with a speculative suggestion for further research.