Hebei University
  • Baoding, China
Recent publications
Lactobacillus rhamnosus and fructooligosaccharides (FOS) have been widely studied so far. However, the effects of L. rhamnosus on the intestinal microecological environment at the species level and the effect of different proportions of FOS on L. rhamnosus colonization in different parts of mice intestine are still unclear. The study results indicated that the specific bands of enterobacterial repetitive intergenic consensus polymerase chain reaction (ERIC-PCR) in the L. rhamnosus (LR) group significantly increased at 7 days. Although the number of bands was similar to the natural recovery (NR) group, the brightness of few bands significantly enhanced in the later stage of recovery. Besides, Southern-blot maps showed strong signals, indicating that the ERIC-PCR fingerprint could accurately reflect the changes in the mouse gut microbiota diversity. Further, the high-throughput results confirmed that the Lactobacillus and Akkermansia had different changes at different periods, but all of them showed an upward trend, while the Klebsiella were inhibited, thereby maintaining the intestinal microecology balance. Moreover, FOS exerted a positive effect on L. rhamnosus colonization in the gut.
The temporal and spatial characteristics of urban river bacterial communities help us understand the feedback mechanism of bacteria to changes in the aquatic environment. The Fuhe River plays an important role in determining the water ecological environment of Baiyangdian Lake. 16S rRNA gene sequencing was used to study the microbial distribution characteristics in the Fuhe River in different seasons. The results showed that some environmental factors of the surface water (ammonia nitrogen (NH3-N), total nitrogen (TN), and total phosphorus (TP)) were different on the spatial and temporal scales. Moreover, there were no seasonal differences in the contents of TN, TP, total organic carbon (TOC), or heavy metals in the sediments. The distributions of Cyanobacteria, Actinomycetes and Firmicutes in the water and Actinomycetes and Planctomycetes in the sediments differed significantly among seasons (P < 0.05). There were significant spatial differences in bacteria in the surface water, with the highest abundance of Proteobacteria recorded in the river along with the highest nutrient concentration, while the abundance of Bacteroidetes was higher in the upstream than the downstream. Microbial communities in the water were most sensitive to temperature (T) and the TP concentration (P < 0.01). Moreover, differences in the bacterial community were better explained by the content of heavy metals in the sediments than by the chemical characteristics. A PICRUSt metabolic inference analysis showed that the effect of high summer temperatures on the enzyme action led to an increase in the abundances of the metabolic-related genes of the river microorganisms.
It is significant to develop low-cost, sensitive, and portable sensing platform for point-of-care testing of ascorbic acid (AA) in food quality evaluation. Herein, a smart point-of-care (SPOC) sensor, consisting of fluorescent paper chip, 3D printed-accessories and smartphone, was developed for ultrasensitive and visual quantitative detection of AA. Fluorescent paper chip was made through printing silicon doped carbon dots (SiCDs)-Fe³⁺ as “ink” onto filter paper, in which SiCDs emitting strong fluorescence signal quenched by Fe³⁺, and then recovered by AA owing to releasing –NH2/–OH and introducing defects on SiCDs. The smartphone with an application named “AA-Tester” was established to analyze AA and exhibited high sensitivity with low detection limits of 18.12 nmol/L. HPLC method was used to verify the SPOC sensor and obtained satisfactory accuracy with relative standard deviations of 0.79–2.31 %. The portable sensing platform integrated fluorescence sensor with smartphone-device will be favorable for ultrasensitive and on-the-spot detection of AA.
Traditionally fermented shrimp paste has a long fermentation period and is susceptible of external factors, which leads to unstable quality and limits its development and application. Therefore, the purpose of this study is to analyze the flavor changes in the shrimp paste fermentation process and screen out the key volatile aroma components in the shrimp paste to control the flavor quality of the shrimp paste products. The overall odor profile was detected by the electronic nose. A total of 106 volatile flavor compounds in the shrimp paste samples at different fermentation stages were identified by solid-phase microextraction-gas chromatography-mass spectrometry (SPME-GC-MS) and headspace-gas chromatography-ion mobility spectrometry (HS-GC-IMS). The main aroma components alcohols, aldehydes, pyrazines and other substances in the fermentation process showed an overall upward trend. A total of 17 key volatile aroma components in shrimp paste at different fermentation stages were identified by the relative aroma activity value (ROAV) method. The combination of electronic nose, SPME-GC-MS and HS-GC-IMS could comprehensively reflect the changes of volatile components in shrimp paste at different fermentation stages, which helps to further understand the mechanism of shrimp paste flavor formation and provides a basis for the regulation of the flavor quality of shrimp paste products.
The majority of long noncoding RNAs (lncRNAs) contain transposable elements (TEs). PAHAL, a nuclear-retained lncRNA that is inserted by a Gypsy retrotransposon, has been shown to be a vital regulator of phenylalanine hydroxylase (PAH) gene expression that controls dopamine biosynthesis and behavioural aggregation in the migratory locust. However, the role of the Gypsy retrotransposon in the transcriptional regulation of PAHAL remains unknown. Here, we identified a Gypsy retrotransposon (named Gypsy element) as an inverted long terminal repeat located in the 3' end of PAHAL, representing a feature shared by many other lncRNAs in the locust genome. The embedded Gypsy element contains a RNA nuclear localization signal motif, which promotes the stable accumulation of PAHAL in the nucleus. The Gypsy element also provides high-affinity SRSF2 binding sites for PAHAL that induce the recruitment of SRSF2, resulting in the PAHAL-mediated transcriptional activation of PAH. Thus, our data demonstrate that TEs provide discrete functional domains for lncRNA organization and highlight the contribution of TEs to the regulatory significance of lncRNAs.
Caspase-mediated cleavage of PARP1 is a surrogate marker for apoptosis. However, the biological significance of PARP1 cleavage during apoptosis is still unclear. Here, using unbiased protein affinity purification, we show that truncated PARP1 (tPARP1) recognizes the RNA polymerase III (Pol III) complex in the cytosol. tPARP1 mono-ADP-ribosylates RNA Pol III in vitro and mediates ADP-ribosylation of RNA Pol III during poly(dA-dT)-stimulated apoptosis in cells. tPARP1-mediated activation of RNA Pol III facilitates IFN-β production and apoptosis. In contrast, suppression of PARP1 or expressing the non-cleavable form of PARP1 impairs these molecular events. Taken together, these studies reveal a novel biological role of tPARP1 during cytosolic DNA-induced apoptosis.
The trivalent lanthanides have been broadly utilized as emitting centers in persistent luminescence (PersL) materials due to their wide emitting spectral range, which thus attract considerable attention over decades. However, the origin of the trivalent lanthanides’ PersL is still an open question, hindering the development of excellent PersL phosphors and their broad applications. Here, the PersL of 12 kinds of the trivalent lanthanides with the exception of La ³⁺ , Lu ³⁺ , and Pm ³⁺ is reported, and a mechanism of the PersL of the trivalent lanthanides in wide bandgap hosts is proposed. According to the mechanism, the excitons in wide bandgap materials transfer their recombination energy to the trivalent lanthanides that bind the excitons, followed by the generation of PersL. During the PersL process, the trivalent lanthanides as isoelectronic traps bind excitons, and the binding ability is not only related to the inherent arrangement of the 4f electrons of the trivalent lanthanides, but also to the extrinsic ligand field including anion coordination and cation substitution. Our work is believed to be a guidance for designing high-performance PersL phosphors.
Symbiotic infection with endophytic fungi has been shown to affect the decomposition rate of host plant leaf litter, but whether this effect is influenced by the presence of arbuscular mycorrhizal fungi (AMF) remains unclear. In this study, we placed litterbags with endophyte-infected (E+) and endophyte-free (E−) Achnatherum sibiricum leaf litter in experimental microcosms in which three AMF inoculation treatments (Funneliformis mosseae, FM; Claroideoglomus etunicatum, CE; and no AMF, NM) were conducted. We then studied the dynamics of mass and nutrient losses and the soil microbial community during a 300-day decomposition period. The presence of endophytes inhibited A. sibiricum litter decomposition, while AMF significantly enhanced the rate of litter decomposition. The degree of inhibition of endophytes was dependent on the AMF species identity. The presence of endophytes significantly decreased the decomposition rate at later decomposition stages under FM inoculation, while the inhibitory effect of endophytes on litter decomposition was eliminated under CE inoculation. In the presence of endophytes, the ratio of carbon to nitrogen in litter increased, which is usually associated with lower decomposition rates. The effect of endophytes on nitrogen accumulation was also influenced by the host plant AMF status, i.e., endophytes reduced nitrogen loss from litter during decomposition only in the FM inoculation treatment. Endophytes had significant negative effects on the biomass of the soil fungal, bacterial and total microbial communities. Our findings suggest that the presence of endophytes can decrease the decomposition rate of A. sibiricum leaf litter directly by altering litter quality and indirectly by inhibiting soil microbial community development during decomposition. Moreover, this inhibitory effect changes depending on the AMF species present. These results may further our understanding of the interactive effects of these two symbionts on nutrient cycling and carbon sequestration in natural communities.
End-substituted planar and twisted isomers (C1 and C2) of pyrene-containing twistacenes were designed and synthesized to investigate the modulation of ectopic substitution on nonlinear optical (NLO) properties. Results of ultrafast transient absorption spectra reveal that C1 exhibits broad-band excited state absorption (ESA), meanwhile C2 displays an additional electronic delocalized state due to charge transfer. The twisted structure caused by large steric hindrance in C2 is thought to be the cause of enhancement according to the density functional theory calculation. Moreover, the evolution of ESA regarding the transition from local excited (LE) to intramolecular charge transfer (ICT) state is observed in the transient spectra. The performance of reverse saturable absorption at 480 nm, 5 ns, is improved by ESA originating from ICT in C2. The extension of π-conjugated system results in a significant enhancement of the two-photon absorption (TPA) cross-section of C1/toluene from 235 to 737 GM at 532 nm. With different substitution positions of terminal group in isomers, TPA and ESA of these chromophores can be dramatically modulated. This work may provide an idea for the optimization of nonlinear functional isomeric materials.
Crystalline and porous covalent organic frameworks (COFs) have attracted extensive attention due to their excellent performance in visible-light-driven hydrogen production. However, further enhancing the separation of photogenerated electron-hole pairs in COFs remains a considerable challenge. Here, we aim to tune semiconductor structures in metal-insulator-semiconductor systems to enhance the separation of the photogenerated carriers in the whole system. The visible-light-driven photocatalytic hydrogen production rate over triformylphloroglucinol (TP)-COF/TiO2 heterojunction which in the case of using polyvinyl pyrrolidone-capped Pt nanoparticles as the cocatalyst is up to 25.9 mmol g⁻¹ h⁻¹, this is three times higher than that of pure TP-COF and ten times higher than TP-COF/TiO2 with Pt as the cocatalyst, respectively. The enhanced photocatalytic performance can not only attribute to the existence of TiO2 acting as the electron collector and transporter but also benefit from the photogenerated electrons that can smoothly tunnel into the Pt nanoparticles by the electrostatic field between the semiconductor and the insulating layer in the metal-insulator-semiconductor system. Both result in more efficient charge separation and greater photoexcitation rates.
Bioimaging plays an important role in cancer diagnosis and treatment. Fluorescence imaging (FI) is one of the most widely applied bioimaging technologies. However, the conventional luminophores usually suffer from the aggregation-caused quenching (ACQ) effect. The aggregation-induced emission luminogens (AIEgens) have been extensively investigated to combat these shortcomings since Tang’s landmark discovery in 2001. Transition metal complex-based AIEgens (TM-AIEgens) combine the advantages of organic AIEgens and transition metal centers to improve photophysical performance and therapeutic outcomes. Herein, we highlight the recent advances in TM-AIEgens applied for cancer diagnosis and theranostics. First, the TM-AIEgens applied for cancer diagnosis were introduced, including isolated cancer cell imaging, tumor microenvironment-responsive imaging, biological process-activated imaging, and tumor tissue-localized imaging. Then TM-AIEgens used for different types of image-guided therapy were presented, including chemotherapy, photodynamic therapy (PDT), photothermal therapy (PTT), radiotherapy, and combination therapy. For each example, we focused on the structure design, the generation mechanism of AIE activity, and the diagnostic or theranostic performance. At last, we discussed the current challenges and opportunities for TM-AIEgens. This review gives a comprehensive landscape of TM-AIEgens in cancer diagnosis and theranostics and will engage more researchers to devote their efforts to this area.
Landscape types with sparse vegetation, gravel cover and ridge-like tillage measures are widely distributed in dryland, and they are the main areas of soil loss and dust emissions caused by soil wind erosion. The widespread land degradation caused by soil wind erosion in these areas is the main reason for the low quality of life of the local people. Therefore, soil wind erosion control has become an urgent task for governments. As is well known, understanding the dynamic process of soil wind erosion is the premise on which effective measures of soil wind erosion control are developed. However, the spatial heterogeneity of shear-stress generated by wind on the soil of rough surfaces and its driving mechanism on soil wind erosion have not been fully understood. Based on a series of wind tunnel experiments, the distribution of wind-caused shear-stress on the exposed soil surface (τs) of rough surfaces with plants, gravels, and ridges was calculated, and the probability density function of τs on these rough surfaces followed the pattern of the logistic function. The location parameter and scale parameter in the logistic function were correlated with the lateral coverage, ridge index and friction wind velocity on rough surfaces. Subsequently, a soil wind erosion rate model with the characteristics of an upscaling point-scale process was established. Tested by multi-source experimental data, the model has a satisfactory prediction ability. These findings greatly improved the understanding of the spatial heterogeneity of τs and the driving mechanism of τs in soil wind erosion, which will help establish a dynamic-based wind erosion rate model in the future.
Let G=(V,E) be a graph with path-length distance function ∂ and diameter d. Let D⊆{0,1,…,d} be a set of distances in G and let ND(x)={y|∂(x,y)∈D} for a fixed vertex x∈V. A bijection φ:V→{1,2,…,|V|} is called a D-magic labeling of G if there exists a constant k such that ∑y∈ND(x)f(y)=k for any x∈V. In this paper, we will study D-magic labelings of the halved n-cube (n≥2) that is on all binary strings of length n with even number of 1s as vertices and edges between any two strings of Hamming distance 2. We prove that the halved n-cube is {1}-magic if and only if n=m2 where m≥2 and m≢0(mod4), and is {0,1}-magic if and only if n=m2+2 where m≥0 and m≢2(mod4).
A thulium-doped fiber laser (TDFL) with bidirectional output was proposed and demonstrated herein. Clockwise (CW) and counter-clockwise (CCW) lasing output with different lasing wavelengths was realized by two uniform fiber Bragg gratings (UFBGs) and two optical circulators. The UFBGs located at 1941.238 and 2049.325 nm were incorporated in the laser cavity to act as the wavelength-selective element. Switchable operation was realized through tuning the gain and loss of the circulating light by applying curvature on a section of the single-mode fiber. When the TDFL was operated in the CW direction, single-wavelength output with a center wavelength, optical signal-to-noise ratio (OSNR), and maximal output power of 2049.335 nm, 33.175 dB, and 280.6 mW was obtained, and the fluctuation of the center wavelength and the output power were less than 0.041 nm and 1.400 dB within an observation time of 60 min. When the TDFL was operated in the CCW direction, single-wavelength output with a center wavelength, OSNR, and maximal output power of 1941.312 nm, 37.108 dB, and 486 mW could be obtained, and the maximal fluctuation of the center wavelength and the output power were 0.128 nm and 0.832 dB within an observation period of 60 min. In addition, the proposed TDFL can operate in both CC and CCW directions simultaneously with different output wavelengths. The potential application of a TDFL strain sensor with sensitivities of 1.33 and 1.22 pm/με in the CW and CCW directions was also demonstrated and the proposed TDFL may also well suited for use in medical and free-space optical communication systems.
Sand production significantly influences the safety and stability of gas hydrate exploitation in reservoirs with high mud content. Gravel packing is an effective method for sand control. The median grain size ratio (D50/d50) values and fine particle content of gravel pack are important factors in sand control during natural gas hydrate exploitation. This paper focuses on the sand blocking effect and permeability characteristics of different grades of gravel. The sand retention test was carried out on four samples with different ratios. The optimal D50/d50 value and fine particle content for gas hydrate production were obtained. A laser particle size analyzer and geotechnical test found the reservoir and gravel layer pore structure change. The results show that the optimal GSR was 24.5, and the optimal fine particle content was about 38%. The permeability decline of the gravel layer occurs in the early stage of production, and the fine particles in the gravel will slow down the degree of seepage damage. For gravel with the same particle size range and different median particle sizes, it has little effect on sand control accuracy but mainly on permeability. The research in this paper can provide a reference for selecting sand control gravel for natural gas exploitation in marine areas.
The logistics carbon emission efficiency takes into account the two goals of economic development and carbon emission reduction, and is an indicator for evaluating the development of a low-carbon economy. This paper mainly discusses the interaction between international trade and logistics carbon emissions. It firstly reviews and sorts out the relevant literature on technology spillovers and carbon emission efficiency in international trade. Then, by analyzing the current situation of China’s economic belt’s import trade and export trade, and by calculating the import trade technology spillover and export trade technology spillover of China’s economic belt from 2017 to 2021, it analyzes the current situation of China’s economic belt and each region of China’s economic belt absorbing technology spillovers from international trade. By analyzing the CO2 emission and economic development of China’s economic belt, the carbon emission efficiency of China’s economic belt can be calculated by using the relationship model between carbon emission and various economic indicators. Then, the panel data model is used to empirically analyze the impact of import trade technology spillovers and export trade technology spillovers on the carbon emission efficiency of China’s economic belt and make regional comparisons. Textile, sewing and leather product manufacturing, chemical industry, metal product manufacturing and machinery and equipment manufacturing saw the largest increases in embodied carbon. In 2017, the embodied carbon in the export trade of textile, sewing and leather product manufacturing increased from 26,761,122 tons to 98,311,041 tons in 2021, and the chemical industry in 2017 increased from 26,413,981 tons to 107,493,401 tons in 2021. This research will help to rationally formulate the carbon emission quota system and improve the supervision system of the carbon trading market.
There remain considerable controversies over payments for ecosystem services (PES) as an essential approach to improving ecosystem services. This study reviewed various definitions of PES and explored its economic nature; then explored previous methods for estimating the PES standard and finally proposed possible agendas for future PES research. Results suggested the PES and traditional land rent both originate from the monopoly of the providers on use rights of land vital to provision of certain ecosystem services, therefore PES should be redefined as a special kind of land rent for sharing land use rights of the providers to guarantee sustainable provision of certain ecosystem services. Besides, there has been no universal methods for estimating the rational PES standard due to insufficient understanding of the economic cause and nature of the PES. Re-imagining and re-designing PES as a system of land rights is advantageous to clearing up misunderstanding and disputes over the economic cause and nature of PES and overcoming limitations of existing methods for estimating the PES standard. Additionally, it is necessary to further improve the PES schemes based on cost-efficiency and explore the methods for estimating the PES standard based on the land rent theory and interdisciplinary knowledge.
Herein, Li7La3Zr2O12 (LLZO) ceramic nano-networks were introduced by electrostatic spinning into the polyethylene oxide (PEO)/thermoplastic polyurethane (TPU)/LiTFSI matrix (PTL) to constitute novel composite solid electrolytes due to the synergy between the nano-networks and the electrolyte matrix. By adjusting the LLZO nanonetwork with different weight ratios (5 wt%, 10 wt%, and 15 wt%) relative to the total weight of the PEO/TPU/LiTFSI/LLZO (PTLL) composite electrolyte, the electrochemical behavior of the gel electrolyte was optimized. When filled with a 10 wt% Li7La3Zr2O12 nano-network, the PTLL has a maximum ionic conductivity of 1.33 × 10⁻³ S cm⁻¹ at 60 °C and an electrochemical stability window of 5.6 V. Furthermore, the LiFePO4/PTLL/Li battery presents an initial specific discharge capacity of 170 mA h g⁻¹ at 0.1 C. After 100 cycles, it demonstrated superior cycle durability at 0.5 C at 60 °C, representing 96.1 % of the initial capacity. These results indicate that the PTLL electrolyte is a promising candidate for advanced solid state lithium batteries.
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657 members
Rui Guo
  • College of Life Sciences
Liu Shuaiqi
  • College o Electronic and Information Engineering
Ying Wang
  • College of Chemistry and Environmental Science
Chao Gao
  • College of Physics Science and Technology
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Baoding, China