Avinashilingam University
  • Coimbatore, India
Recent publications
Sentiment analysis is a prominent research topic in natural language processing, with applications in politics, news, education, product review, and other sectors. Especially in the education sector, sentiment analysis can assist educators in finding students’ feelings about a course on time, altering the teaching plan appropriately and timely to improve the quality of education and teaching. For students, the sentiment analysis can identify emotions, academic performance, behaviour, and so on; the primary purpose of this research paper is to analyze students’ emotions, self-esteem, and efficacy based on closed-ended questionnaires. This paper proposes Quest_SA, which uses the sentiment analysis technique to identify students’ emotions based on the answer provided by a closed-ended questionnaire. The polarity value is assigned for each questionnaire scale. The students’ responses are then gathered using a closed-ended questionnaire, and the student’s emotions are classified using a polarity-based method of sentiment analysis. Finally, sentiment scores and emotion variance were used to evaluate the outcomes. According to the sentiment ratings, students have favourable sentiments and emotions such as unhappy, somewhat happy, and happy. The real-world closed-ended questionnaires such as emotional intelligence, Eysenck, personality, self-determination scale, self-efficacy, Rosenberg’s self-esteem, positive and negative affect schedule, and Oxford happiness questionnaires were used to examine the academic performance with the proposed sentiment analysis. This study inferred that the proposed sentiment analysis preprocessing method with polarity scores is as accurate as the standard value calculation.
Aspergillosis is a dreadful fungal infection and are more predominant in clinical fields. Due to the limitation of antifungal drugs, there is an emergence to develop efficient antifungal compounds from natural sources. Hence, the present study deals with the validation of active compounds from Aspergillus giganteus against aspergillosis causing Aspergillus fumigatus. The most prominent antifungal proteins in Aspergillus giganteus are sarcin, thionin and chitinase. Initially, the bioavailability and toxicological properties of sarcin, thionin, chitinase and their derivatives were screened. The molecular interaction of the screened antifungal proteins against the target proteins (UDP-N-acetylglucosamine pyrophosphorylase, N-myristoyl transferase and Chitinase) of Aspergillus fumigatus was performed using Schrodinger module. The antagonistic potential of antifungal compounds on the pathogen was confirmed by SEM. The integrity of Aspergillus fumigatus cell membrane and nuclear membrane treated with antifungal compounds were analysed by determining the release of cellular materials. Further, the GC-MS profiling of volatile bioactive compounds were analysed. The results have proved the efficiency of selected compounds for their pharmacokinetic properties. Molecular interactions of selected compounds from Aspergillus giganteus with the virulence proteins of Aspergillus fumigatus have exhibited a good glide score and their druggable nature. The SEM analysis have envisaged the shrunken and damaged spores of A. fumigatus treated with antifungal compounds. The effective concentration of antifungal compounds (AFCs) was found to be 250 µg/ml (p<0.0001). The GC-MS profiling has revealed the volatile bioactive metabolites present in Aspergillus giganteus. Conclusively, the selected antagonists from Aspergillus giganteus can be a good drug candidate to treat aspergillosis.
The current generation of solar cells are playing a predominant role in the energy storage industries since they are found to be economic, abundant, and compact design for photovoltaic applications. In this context, composite materials based on perovskite zinc titanate nanoparticles (ZnTiO3 NPs) and perovskite zinc titanate-reduced graphene oxide nanocomposite (RGO-ZnTiO3 NC) were prepared by a simple sol-gel technique. The ZnTiO3 NPs and RGO-ZnTiO3 NC were subjected to X-ray diffraction analysis for calculating crystal structure, crystallite size, microstrain, and dislocation density. The band gap energy of the ZnTiO3 NPs and RGO-ZnTiO3 NCs was found to be 2.9 and 3.1 eV, respectively. X-ray photoelectron spectroscopy was used to determine the elemental species of the RGO-ZnTiO3 NC. The photovoltaic performance of the dye-sensitized solar cell (DSSC) with RGO-ZnTiO3 NC exhibited strong dye adsorption to facilitate considerable light absorption and efficient electron transport, due to less surface trapping sites compared to unmodified ZnTiO3NPs photoanode based DSSC. The RGO-ZnTiO3 NC photoanode demonstrated the best photovoltaic performance with a short-circuit current density of 4.27 mA cm⁻² and better photoelectric conversion efficiency of 1.11%, which is ∼2.6 folds higher than the DSSC with ZnTiO3 NPs photoanode.
To assess the burden of type 2 diabetes (T2D) and its genetic profile in endogamous populations of India given the paucity of data, we aimed to determine the prevalence of T2D and estimate its heritability using family-based cohorts from three distinct Endogamous Ethnic Groups (EEGs) representing Northern (Rajasthan [Agarwals: AG]) and Southern (Tamil Nadu [Chettiars: CH] and Andhra Pradesh [Reddys: RE]) states of India. For comparison, family-based data collected previously from another North Indian Punjabi Sikh (SI) EEG was used. In addition, we examined various T2D-related cardiometabolic traits and determined their heritabilities. These studies were conducted as part of the Indian Diabetes Genetic Studies in collaboration with US (INDIGENIUS) Consortium. The pedigree, demographic, phenotypic, covariate data and samples were collected from the CH, AG, and RE EEGs. The status of T2D was defined by ADA guidelines (fasting glucose ≥ 126 mg/dl or HbA1c ≥ 6.5% and/or use of diabetes medication/history). The prevalence of T2D in CH (N = 517, families = 21, mean age = 47y, mean BMI = 27), AG (N = 530, Families = 25, mean age = 43y, mean BMI = 27), and RE (N = 500, Families = 22, mean age = 46y, mean BMI = 27) was found to be 33%, 37%, and 36%, respectively, Also, the study participants from these EEGs were found to be at increased cardiometabolic risk (e.g., obesity and prediabetes). Similar characteristics for the SI EEG (N = 1,260, Families = 324, Age = 51y, BMI = 27, T2D = 75%) were obtained previously. We used the variance components approach to carry out genetic analyses after adjusting for covariate effects. The heritability (h2) estimates of T2D in the CH, RE, SI, and AG were found to be 30%, 46%, 54%, and 82% respectively, and statistically significant (P ≤ 0.05). Other T2D related traits (e.g., BMI, lipids, blood pressure) in AG, CH, and RE EEGs exhibited strong additive genetic influences (h2 range: 17% [triglycerides/AG and hs-CRP/RE] - 86% [glucose/non-T2D/AG]). Our findings highlight the high burden of T2D in Indian EEGs with significant and differential additive genetic influences on T2D and related traits.
Plasmonic silver nanoparticles loaded strontium titanate nanocomposites (Ag-SrTiO3 NC) with diverse weight percentages (0.5, 1.5, 2.5 and 5 wt%) of Ag nanoparticles (Ag NPs) are synthesized by a facile chemical reduction method. The prepared nanocomposites are characterized using diffuse reflectance spectroscopy, X-ray diffractometry, photoluminescence spectroscopy, scanning electronic microscopy and transmission electron microscopy. The photovoltaic performance of dye-sensitized solar cells (DSSCs) integrated with Ag-SrTiO3 NC photoanodes has been assessed under simulated sun light intensity of 100 mW cm–2. The Ag-SrTiO3 NC photoanode loaded with 2.5 wt% Ag NPs exhibited higher power conversion efficiency of 4.39% with short-circuit photocurrent density of 11.54 mA cm⁻², open circuit voltage of 0.77 V and fill factor of 0.49 in DSSC. This enhanced photovoltaic performance can be credited to high dye loading, improvement in visible light harvesting property and fast photo-induced electron transfer caused by the plasmonic Ag NPs.
Tantalate semiconductor photocatalyst has received significant attention as an alternative promising material to mitigate the globally increasing energy demand with the course of action of the produced hydrogen. In this report, an efficient enhancement in the hydrogen production under ultraviolet (UV) light by Ag‐ and N‐doped LiTaO3 via solvothermal strategy is proposed. The structural appearance and the spherical morphology are affirmed from the X‐ray diffraction and field emission scanning electron microscopy (FESEM) analysis. The bandgap of the prepared photocatalysts is calculated as 5.12, 4.92, and 4.82 eV for undoped LiTaO3, Ag, and N‐doped LiTaO3 nanoparticles using Tauc's plot. Moreover, the band position of the synthesized LiTaO3 and also with its dopants is calculated by the Mulliken electro negativity method. The elemental composition of the synthesized photocatalyst is confirmed from the energy dispersive analysis (EDS). Photocatalytic water splitting results over Ag‐ and N‐doped LiTaO3 photocatalyst showed that the rate of H2 evolution from formic acid aqueous solution was 240 and 123 μmolh−1 with an apparent quantum yield of 3.11% and 1.59%, whereas for undoped LiTaO3, the rate is quite lower to be 71 μmolh−1. The reason behind the high catalytic activity of Ag‐doped LiTaO3 is explained by the fact that the higher electronegativity of Ag (1.93) as compared with Ta (1.5) resulted in quite transfer of photoexcited electrons from the conduction band of LiTaO3 to the Ag species. Interestingly, up to the best of our knowledge, this is the first study regarding the photocatalytic hydrogen evolution for Ag‐ and N‐doped LiTaO3. LiTaO3 perovskite and also with its dopants are synthesized by solvothermal method, and its structural and optical characteristics were analyzed. Photocatalytic H2 evolution measurements are carried out for LiTaO3 and also with Ag and N dopants under UV light. It showed that the rate of H2 as 240 μmolh−1 is attained for Ag‐doped LiTaO3.
The RGO-Y 2 O 3 and RGO-Y 2 O 3 : Cr ³⁺ (5 mol %) nanocomposite (NC) synthesized a simple hydrothermal technique. The structure and morphology of the synthesized NCs were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). Y 2 O 3 :Cr ³⁺ display spherical shaped particles. Conversely, the surface of the RGO displays a wrinkly texture connecting with the existence of flexible and ultrathin graphene sheets. The photoluminescence (PL) emission spectra showed series of sharp peaks at 490, 591, and 687 nm which corresponding to ⁴ F 9/2 → ⁶ H 15/2 , ⁴ F 9/2 → ⁶ H 13/2, and ⁴ F 9/2 → ⁶ H 11/2 transitions and lies in the blue, orange, and red region. The prepared NCs were used for the preparation of modified carbon paste electrodes (MCPE) in the electrochemical detection of dopamine (DA) at pH 7.4. Both modified electrodes provide a good electrocatalytic activity for the voltametric detection of DA. Doping is an effective method to improve the conductivity of Y 2 O 3 :Cr ³⁺ and developed a method for the sensor used in analytical applications.
Ovarian cancer (OC) is a complex multifactorial malignancy, ranking as second most common reproductive cancer in India. The purpose of this study was to compare whether different characteristics combined with hormonal and genetic influence among the urban, rural and tribal populations affected with OC would have a significant impact on OC incidence. To address this challenge, we designed a statistical approach that combines individual-level epidemiological data from both OC patients and controls from designed study populations using questionnaires. A total of ( n =72) OC patients were obtained from several oncological clinics, hospitals and population-based surveys from various districts of South Indian population. Using validated hormonal biomarkers, we estimated hormonal profiles in both OC subjects and controls to measure the role of hormones in OC severity and incidence. Further we conducted mitochondrial gene sequencing, we found 5 nucleotide changes among which MT9140 C>T) was the predominant in OC subjects. In conclusion, this kind of study would be the first of its kind, where population-based epidemiological surveys serve as keys for comparing the characteristic factors and genetic influence associated with OC incidence. Hence, we strongly recommend that frequent conduction of epidemiological studies and health awareness camps would be beneficial to overcome such lethal conditions.
This work precisely deals with the phenomena of state tracking, attenuation of external disturbance and compensation of input delay for switched stochastic dynamical systems via improved‐equivalent‐input‐disturbance (IEID) estimator and Smith predictor based modified repetitive control design. By hosting the stochastic state observer and combining it with the IEID estimator and modified repetitive control design, a new closed‐loop form of control system is formulated. To be specific, for the resultant closed‐loop augmented configuration, a novel criterion which ensures the exponential stability of the considered system is derived in the form of linear‐matrix‐inequalities in accordance with the Lyapunov theory. Simultaneously, an IEID estimator and Smith predictor based modified repetitive control is designed in such a way that the states of the considered system track the specific reference input signals perfectly. Finally, as an example F‐18 aircraft model is provided for describing the competence of the designed controller strategy and to explain the dominance of the obtained proposed controller over the existing results.
Empowerment of women is a relevant field. Compared to any other state in India, Kerala has a good literacy rate, and Thiruvananthapuram is the capital city. This study is analyzing women's education since the independence of Thiruvananthapuram. Significant changes and improvement were identified through 60 samples from selected areas. Data were collected from respondents through interview schedule and survey methods and also from the DPI. The obtained data were analyzed through appropriate statistical tools. The present study showed that women's participation in education was improved and dropouts of women from education also decreased. Still, they experience restriction from some of the socio-cultural beliefs of their family, but involvement of government in women's education has made great progress.
Educational data mining is a research field that is used to enhance education system. Research studies using educational data mining are in increase because of the knowledge acquired for decision making to enhance the education process by the information retrieved by machine learning processes. Sentiment analysis is one of the most involved research fields of data mining in natural language processing, web mining, and text mining. It plays a vital role in many areas such as management sciences and social sciences, including education. In education, investigating students' opinions, emotions using techniques of sentiment analysis can understand the students' feelings that students experience in academic, personal, and societal environments. This investigation with sentiment analysis helps the academicians and other stakeholders to understand their motive on education is online. This article intends to explore different theories on education, students' learning process, and to study different approaches of sentiment analysis academics.
Herein, we delineate the enhancement of the dielectric properties of an anionic dye doped triglycine acetate crystal for the first time. Single crystals of pure triglycine acetate (TGAc) and reactive orange 16 (RO16) dye-doped (0.01, 0.03 mol%) triglycine acetate were synthesized with an intention to enhance the strengths of pure TGAc crystal using slow evaporation process. The crystalline structure and phase purity of the grown crystals were analyzed using Powder XRD studies. The frequency dependence of real and imaginary part of dielectric constant, loss tangent, real and imaginary part of impedance, electrical modulus and ac electrical conductivity have been investigated. The dielectric constant and dielectric loss for the grown crystals, have been found to decrease with increasing frequency. The decrease in permittivity and dielectric loss with an increase in applied field frequency is as per Maxwell–Wagner theory. The Cole–Cole plot implies that the mechanism of conduction is mainly due to bulk resistance. The enhanced dielectric constant of the doped crystals confirms the appropriateness of the developed crystals for energy storage capacitor applications.
Epigenetic mechanisms play an important part in the regulation of gene expression and these alterations may induce long-term changes in gene function and metabolism. They have received extensive attention in bridging the gap between environmental exposures and disease development via their influence on gene expression. DNA methylation is the earliest discovered epigenetic alteration. In this review, we try to examine the role of DNA methylation and histone modification in Age related macular degeneration (AMD) and Diabetic Retinopathy (DR), its vascular complications and recent progress. Given the complex nature of AMD and DR, it is crucial to improve therapeutics which will greatly enhance the quality of life and reduce the burden for millions of patients living with these potentially blinding conditions.
The main objective of this project was, therefore, to design and develop a RFID based PRMIS using Laboratory Virtual Instrumentation Engineering Workbench (LabVIEW) that would automate patient information management and give direct benefit in certain terms. The patient is provided with a RFID card and the patient information is accessed. The proposed system helps to reduce the manual paper work in the hospital. It also aims at building accuracy in entering the details electronically and the patients data can be retrieved easily.
The marine invertebrates are vast species in the animal kingdom which consists abundant source of novel functional biopolymers like proteins, lipid and polysaccharides that possess numerous biological activities. These biopolymers had been used for multiple application and served as a functional food for health perspective. In recent times, marine organisms were effectively investigated for potential pharmaceuticals and natural drugs. Besides, marine invertebrate proteins including peptides served as a traditional food and effective alternative medicine for infectious disease. This review focuses on antioxidant, anticancer, antimicrobial activities of peptides and protein including collage and gelatin, were critically analysed with global market status of protein and peptides from marine invertebrates. Hence, this would give more insight on functional property of marine invertebrate, and their applications in biomedical and food industrial application. Keywords: Marine invertebrates, Functional protein, Collagen, Gelatin, Molecular weight, Biological activity
The present study evaluated the nutritional composition of under-exploited edible seaweeds and its comparison with recommended dietary allowances (RDA) of pregnant women. Some under-exploited seaweeds were identified such as Acanthophora spicifera, Gracilaria edulis, Padina gymnospora, Ulva fasciata and Enteromorpha flexuosa were not utilized directly as a food, thus evaluated their wholesome nutrients for food application. Results showed that micronutrients were found to be high in selected seaweeds such as iron in the range of 14.8–72 mg/100 g, iodine 38.8–72.2 mg/100 g, and calcium 410–870 mg/100 g. The essential aminoacids were between 189.2 and 306 mg/g, essential fatty acid like arachidonic acid was 0.80% and 0.59% of linoleic acid, monounsaturated fatty acid were 3.05–14.08% in U. fasiciata. Heavy metals were within the tolerable limit, mercury was found 0.030 ppm A. spicifera and not detected in other species, arsenic 0.012–0.076 ppm, cadmium content ranges between 0.012 and 0.081 ppm in all species. These nutrients meet more than 70% of macro and micronutrients in precise combination of RDA suggested for pregnant women. Therefore, seaweed would be better alternative food source to meet food security challenges. Keywords: Seaweeds, Amino acid, Fatty acid, Food security, Recommended dietary allowances
Polymer electrolytes are the emerging materials for electrochemical device applications such as high energy density batteries, fuel cells, supercapacitors, electrochromic displays, etc. Polymer electrolytes has gone through different developmental stages, starting from dry solid polymer electrolyte (SPE) systems to plasticized, gels, rubbery to micro/nano-composite polymer electrolytes. The main two factors that retard the applications of synthetic polymer electrolytes are High cost and not “environmentally green”. Hence to overcome this shortcomings of synthetic polymers biopolymers have gained enormous attention which raises the significance due to global warming and energy crisis. The present work focuses on the characteristics of bio polymer electrolyte based on pectin and lithium nitrate. The electrolytes were prepared using the solution casting method. A.C. impedance spectroscopy shows that the biopolymer containing 30 wt% Pectin: 70wt%LiNO3 has highest ionic conductivity of 3.97 x 10⁻³ Scm⁻¹ [1]. The analysis also proves that the magnitude of ionic conductivity increases with an increase in temperature for which the activation energy is minimum. The values of glass transition temperature (Tg) using differential scanning calorimetry (DSC) analysis predicts values, which reveals that the Tg value increase with respect to the increase of LiNO 3. Transference number measurement confirms that the conducting species are Li ion. Primary lithium-ion battery has been constructed using best conducting bio polymer electrolyte membrane, and the open circuit voltage (OCV) has been observed as 1.4 V.
Seaweeds are known to be rich source of micronutrients and bioactive compounds. The main objective of this study was to find the toxicological evaluation and heavy metal accumulation of five under-exploited edible seaweeds in animal model followed by dosage determination for regular consumption as a food by humans and food application. Some under-exploited seaweeds like Acanthophora spicifera, Gracilaria edulis, Padina gymnospora, Ulva fasciata and Enteromorphoa flexuosa were selected forthis study. The ED50 study was conducted in Wistar strain rats for 90 days with single dose administration of seaweed extract of 2000 mg/kg/BW. At the end of 90th day rats were euthanized, serum of the rats examined for biochemical, haematological, liver enzymes, and vital organs were dissected out for heavy metal analysis and urine samples collected intermediary to analyse electrolyte minerals. Result showed that no-observed adverse effect level (NOEL) on five seaweeds, did not cause any death and no significant variation in biochemical and haematological parameters, the values were found within standard values. Locomotor activity suggests normal action, organ necropsy showed no histopathology lesions, regular cell alignment in the tissue cross section. Heavy metals like arsenic, lead were found in trace amount and no mercury accumulation found in kidney, liver and brain of rats. Therefore, these five seaweeds were safe for human consumption and also for food product developement. Keywords: Seaweed, Sub-chronic toxicity, Acanthophora spicifera, Gracilaria edulis, Padina gymnospora, Ulva fasciata, Enteromorphoa flexuosa
Mesoporous nanocrystalline metal oxides such as TiO2, SnO2, and TiO2-SnO2 composites form a new class of mesoporous inorganic solids, which exhibit excellent structural, textural, optical, and photocatalytic properties. Furthermore, they also possess a large number of surface-exposed catalytic active sites in addition to their intrinsic flexible diffusion characteristics. In this investigation, we report the photocatalytic activity of high-quality mesoporous TiO2, SnO2, and TiO2-SnO2 composites. All the catalysts were tested for photocatalytic degradation of 4-chlorophenol under a solar simulator. The reaction results indicate that the anatase-phase mesoporous Ti0·9Sn0·1O2 exhibits enhanced activity as compared with the commercial TiO2 (P-25).
Institution pages aggregate content on ResearchGate related to an institution. The members listed on this page have self-identified as being affiliated with this institution. Publications listed on this page were identified by our algorithms as relating to this institution. This page was not created or approved by the institution. If you represent an institution and have questions about these pages or wish to report inaccurate content, you can contact us here.
1,397 members
Ebenesar Anna Bagyam
  • Department of Mathematics
Sripathi Shubashini
  • Department of Chemistry
Kalaiselvi Senthil
  • Department of Bio-chemistry/ Bio-technology/ Bio-informatics
Parthasarathy Subashini
  • Department of Computer Science
Nalini Balakrishnan
  • Department of Physics
Coimbatore, India