Recent publications

- Elad Aigner-Horev
- Yury Person

A classical result by Rado characterises the so-called partition-regular matrices A, i.e. those matrices A for which any finite colouring of the positive integers yields a monochromatic solution to the equation Ax=0. We study the asymmetric random Rado problem for the (binomial) random set [n]p in which one seeks to determine the threshold for the property that any r-colouring, r≥2, of the random set has a colour i∈[r] admitting a solution for the matrical equation Aix=0, where A1,…,Ar are predetermined partition-regular matrices pre-assigned to the colours involved.
We prove a 1-statement for the asymmetric random Rado property. In the symmetric setting our result retrieves the 1-statement of the symmetric random Rado theorem established in a combination of results by Rödl and Ruciński [34] and by Friedgut, Rödl and Schacht [11]. We conjecture that our 1-statement in fact unveils the threshold for the asymmetric random Rado property, yielding a counterpart to the so-called Kohayakawa-Kreuter conjecture concerning the threshold for the asymmetric random Ramsey problem in graphs.
We deduce the aforementioned 1-statement for the asymmetric random Rado property after establishing a broader result generalising the main theorem of Friedgut, Rödl and Schacht from [11]. The latter then serves as a combinatorial framework through which 1-statements for Ramsey-type problems in random sets and (hyper)graphs alike can be established in the asymmetric setting following a relatively short combinatorial examination of certain hypergraphs. To establish this framework we utilise a recent approach put forth by Mousset, Nenadov and Samotij [26] for the Kohayakawa-Kreuter conjecture.

Introduction
Weight stigmatization, a common phenomenon in the healthcare system, exerts numerous adverse consequences on patients' wellbeing. The objective of this study was to estimate the extent and characteristics of weight stigmatization in Israel, based on the reports of overweight and obese individuals.
Methods
This study was performed by distribution of a cross-sectional open anonymous survey in social media platforms, targeting respondents with body mass index over 25 kg/m ² . The questionnaire consisted of Likert-scale based as well as open-ended questions, evaluating the experience during past medical appointments. Our primary outcome was the prevalence of disrespectful treatment. Subgroup analysis was performed by various demographic characteristics.
Results
Of the 1697 respondents, 59.0% reported frequent experiences of disrespectful approach, and 48.6% noted receiving suboptimal treatment related to excess weight. Insulting, insensitive and judgmental comments were noted by 58%, stemming from diverse healthcare disciplines, while 29.3% noted office equipment not suitable for overweight people. Avoidance of a needed medical appointment was reported by 40.5%, significantly associated with past adverse experiences of weight stigmatization in the healthcare system. The respondents offered numerous suggestions to improve the existing situation, including education of the medical personnel, thorough research of obesity, and establishment of specific guidelines for approach to patients with excess weight.
Conclusion
Weight stigmatization is prevalent in Israeli healthcare system; thus, decreasing the rates of this phenomenon should be an important national goal. Formal education about the wide prevalence and adverse effects of weight stigmatization should be practiced by academic institutions, professional organizations, and regulatory bodies. Straightforward policies with continuing supervision should be endorsed by the healthcare system to prevent weight-based discrimination. Finally, appropriate-size equipment for obese patients should become one of the requirements for accreditation of medical centers and facilities.

Background
Previous experiments in tacit coordination games hinted that some people are more successful in achieving coordination than others, although the variability in this ability has not yet been examined before. With that in mind, the overarching aim of our study is to model and describe the variability in human decision-making behavior in the context of tacit coordination games.
Methods
In this study, we conducted a large-scale experiment to collect behavioral data, characterized the distribution of tacit coordination ability, and modeled the decision-making behavior of players. First, we measured the multimodality in the data and described it by using a Gaussian mixture model. Then, using multivariate linear regression and dimensionality reduction (PCA), we have constructed a model linking between individual strategic profiles of players and their coordination ability. Finally, we validated the predictive performance of the model by using external validation.
Results
We demonstrated that coordination ability is best described by a multimodal distribution corresponding to the levels of coordination ability and that there is a significant relationship between the player’s strategic profile and their coordination ability. External validation determined that our predictive model is robust.
Conclusions
The study provides insight into the amount of variability that exists in individual tacit coordination ability as well as in individual strategic profiles and shows that both are quite diverse. Our findings may facilitate the construction of improved algorithms for human–machine interaction in diverse contexts. Additional avenues for future research are discussed.

The Laser Interferometer Space Antenna (LISA) has the potential to reveal wonders about the fundamental theory of nature at play in the extreme gravity regime, where the gravitational interaction is both strong and dynamical. In this white paper, the Fundamental Physics Working Group of the LISA Consortium summarizes the current topics in fundamental physics where LISA observations of gravitational waves can be expected to provide key input. We provide the briefest of reviews to then delineate avenues for future research directions and to discuss connections between this working group, other working groups and the consortium work package teams. These connections must be developed for LISA to live up to its science potential in these areas.

Inspite of being a good triplet sensitizer, benzophenones are not useful as host materials for phosphorescent organic light-emitting diodes (PhOLEDs), primarily due to their low thermal stability. In this work, we have addressed this shortcoming by judicial tethering of benzoyl units onto different positions of a rigid Tröger’s base (TB) scaffold to develop two new benzophenone tethered TBs, namely TB-Bz1, and TB-Bz2 as thermally stable host materials for applications in PhOLEDs. The TB-based host molecules were readily synthesized in good yields from the corresponding amines, and were fully characterized using various spectroscopic techniques. These TBs displayed high thermal decomposition temperatures above 320 °C, imparted by the rigid, non-planar, boomerang-shaped scaffold of the Tröger’s base. It was further observed that the tethering position of the benzoyl units can significantly affect the photophysical properties of the TBs due to the twisting of the benzoyl unit with respect to the TB-core. This assumption was further confirmed by DFT simulations. Taking advantage of the high triplet energy of TBs (>2.8 eV), PhOLED devices were fabricated exploring TBs as the host material and Ir(ppy)3 as the dopant. The maximum external quantum efficiency of 6.1 %, and 6.9 % and maximum luminance of greater than 5000 cd/m² were obtained using TBs as the host for the proof-of-concept PhOLED devices, where Ir(ppy)3 was employed as the dopant.

Let Qn,d denote the random combinatorial matrix whose rows are independent of one another and such that each row is sampled uniformly at random from the subset of vectors in {0,1}n having precisely d entries equal to 1. We present a short proof of the fact that P[det(Qn,d)=0]=O(n1/2log3/2nd)=o(1), whenever ω(n1/2log3/2n)=d≤n/2. In particular, our proof accommodates sparse random combinatorial matrices in the sense that d=o(n) is allowed.
We also consider the singularity of deterministic integer matrices A randomly perturbed by a sparse combinatorial matrix. In particular, we prove that P[det(A+Qn,d)=0]=O(n1/2log3/2nd), again, whenever ω(n1/2log3/2n)=d≤n/2 and A has the property that (1,−d) is not an eigenpair of A.

Research often fails to be translated into applications because of lack of financial support. The Proof of Concept (PoC) funding scheme from the European Research Council (ERC) supports the early stages of the valorization process of the research conducted by its grantees. This article explores the factors that predict who will apply for ERC grants and which grant proposals will prove successful. By combining information from two datasets of 10,074 ERC grants (representing 8361 individual grantees) and 2186 PoC proposals, and using automated machine learning, we can identify the main predictors of the propensity to apply and to win. Doing so fills a void in the literature on likelihood to apply. The results reveal major differences between potential and actual beneficiaries, due to decisions about applying for a grant and evaluations of the proposals. The decision to apply is affected by the interaction between the characteristics of the PoC funding scheme, the ERC grantee, and his/her environment. Grantees in countries that invest little in innovation, with low cost of personnel, and strong collaboration in innovation are more likely to apply. Male grantees are more likely to apply but have similar chances of winning as women.

Background
A growing literature underscores the role played by sibling throughout life particularly for siblings with disabilities. However, limited research focuses on how growing up with a sibling with a disability impacts adult personality and well-being.
Aims
The current study is a qualitative examination of the long-term effects of growing up with a sibling who has a developmental disability, using both a deficiency and growth model perspective.
Methods and procedures
Participants included 20 adult siblings of individuals with disabilities interviewed using a semi-structured interview. Interviews were conducted via an online platform.
Outcomes and results
Themes identified were: impact on personal character traits, social development through sibling and overcoming social challenges, impacts on religiosity, influence on career choice, influence on romantic relationships and finding a partner, and future planning and stress. Distinct patterns of growth were noted in areas of personal development, character traits, social development, and interpersonal skills. On the other hand, hardships and anxieties were noted in general with specific negative features relating to social embarrassment and concerns about how the sibling status will impact potential romantic partnerships and future family life.
Conclusions and implications
The current study highlights the long-term impact of growing up with a sibling with a developmental disability with empirical and clinical implications.

- Michał Artymowski
- Ido Ben-Dayan
- Utkarsh Kumar

In a recent paper [Artymowski et al., Phys. Rev. D 103, L121303 (2021)] we suggested the possibility that the present acceleration of the Universe is due to thermodynamical behavior of unparticles. The model is free of scalar fields, modified gravity, a cosmological constant, the coincidence problem, initial conditions problem and possesses interesting distinct predictions regarding the equation of state of dark energy, the growth rate and the number of relativistic degrees of freedom at big bang nucleosynthesis and cosmic microwave background decoupling. In this work we relate to a recent paper [Abchouyeh and van Putten, Phys. Rev. D 104, 083511 (2021)], which discusses a similar setup of unparticles with and without a cosmological constant as an external source of late-time acceleration. The authors have shown how such a model is inconsistent with the data. We show that these claims are viable only in a particular part of the parameter space and that the model of Artymowski, Ben-Dayan, and Kumar stands tall. We further suggest a consistency condition in terms of observables. We then fit publicly available supernovae data to derive the expected Hubble parameter and constrain the parameters of the model.

Objectives:
Here, we aimed to (a) determine whether a clinically significant sensorineural hearing loss (SNHL) change could be detected in post-coronavirus disease (COVID-19) hearing levels on comparing them with pre-infection hearing levels after controlling for the effect of age and (b) to identify risk factors, such as hypertension, diabetes, and smoking, which increase the likelihood of hearing loss in COVID-19 patients.
Methods:
We retrospectively analyzed hearing thresholds in unvaccinated patient's pre- and post-COVID-19 infection. Thresholds were controlled for age and the duration between the pre- and post-COVID-19 hearing evaluations. Correlations between additional COVID-19-related symptoms, hypertension, diabetes, and smoking and hearing threshold changes were analyzed.
Results:
A significant (but not clinical) threshold elevation was found post-COVID-19 infection. However, on controlling for age and the duration between the pre- and post-COVID-19 hearing evaluations, no significant threshold elevation was found. No significant correlation was found between hearing threshold changes and additional COVID-19-related symptoms, hypertension, diabetes, or smoking.
Conclusion:
COVID-19 did not lead to a significant hearing threshold elevation in our cohort, even among patients with additional COVID-19 symptoms, hypertension, or diabetes mellitus or among those who smoked.
Level of evidence: 3:
nonrandomized controlled cohort, follow-up study Laryngoscope, 2022.

There is potential to improve low colorectal cancer screening rates, reduce mortality, and narrow health disparities, if the distinctive screening barriers among Russian-speaking immigrants were better understood. However, there is little relevant research about the topic. To address this gap, this study aimed to identify barriers to timely colorectal cancer screening, especially colonoscopies, among Russian-speakers in New York City. Thirteen key informant interviews were performed with providers, community leaders, and academics. Eight focus groups were then conducted with 81 Russian-speaking individuals, age 50–75, who had not had a timely colonoscopy. Results were translated, transcribed, coded and analyzed. Barriers identified included individual, communal, and structural issues. Distinctive barriers, such as those related to culture and to the experiences of living under the Soviet system, were uncovered. Barriers identified can potentially be reduced through interventions suggested by the research, including more education and more effective provider recommendations.

Since professionals in today's world belong to multiple social groups (e.g., age, religion, and gender), their personal identities may challenge the development of their professional identity. The theoretical framework of intersectionality provides a useful lens to examine the complexity of developing a multi-faceted professional identity. This study explored the experiences of female Jewish Ultra-Orthodox occupational therapists, who constitute agents of change in their community. It analyzes the challenges they face when their professional identity intersects with their gendered and religious identities. A thematic analysis of dilemma cases written by occupational therapy students revealed six key themes which suggest professional identity is neither unified nor exclusive, and hence cannot be developed without considering the impacts of each. These findings challenge previous studies of intersectionality that have focused on oppression and discrimination by suggesting that intersectionality, even when associated with disadvantaged social groups, can be harnessed to engender change, empowerment and growth. This study provides an opportunity to theorize the intersectionality of profession, gender and religion in organizational settings. It shows that viewing professional identity as multi-faceted may be of crucial importance as today's workforce becomes more culturally diverse, and inclusion dominates human resource management decision-making. The practical implications for management and curricula are discussed.

Next-generation fuels are defined as those produced from non-food resources. A leading member in this group is dimethyl ether− DME (C2H6O), which is a high-energy, non-toxic gas, produced from a wide range of carbon feedstocks and wastes. We explored the oxidation of DME on a highly active catalyst based on Pt3Pd3Sn2 with an atokite structure in comparison to Pt3Sn and Pd3Sn. Following a comprehensive characterization of the new ternary catalyst by electron microscopy, X-ray diffraction, and photoelectron spectroscopy, the DME anodic reaction was analyzed by electrochemical online mass spectrometry of fuel cell gas emission product and supported by density functional theory (DFT) calculations. Pt3Pd3Sn2 catalyst exhibits optimal binding energy (−0.21 eV) and the lowest activation energy for electrochemical oxidation of DME (48.7 kJ mol⁻¹ at 0.80 V). A few preferred oxidation routes were examined at different potentials corroborating with the identified CO2, formic acid, methanol, and methyl-formate by in-operando online mass spectrometry. Fuel-cell constructed using a Pt3Pd3Sn2/C anode catalyst and commercial Pt/C cathode catalyst, delivered an open circuit voltage of 0.9 V, a peak power density of 220 mW cm⁻² at 0.40 V and a gravimetric power density of 135 mW mgpgm⁻¹ at ambient pressure and 80 °C, which exceeded the highest values reported so far for direct DME fuel cells.

If α(G)+μ(G)=V\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\alpha (G)+\mu (G)=\left| V\right|$$\end{document}, then G=V,E\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$G=\left( V,E\right)$$\end{document} is a König–Egerváry graph, where α(G)\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\alpha (G)$$\end{document} denotes the cardinality of a maximum independent set, while μ(G)\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\mu (G)$$\end{document} is the size of a maximum matching in G. If d1≤d2≤⋯≤dn\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$d_{1}\le d_{2}\le \cdots \le d_{n}$$\end{document} is the degree sequence of G, then the annihilation numberaG\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$a\left( G\right)$$\end{document} of G is the largest integer k such that ∑i=1kdi≤E\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\sum \limits _{i=1} ^{k}d_{i}\le \left| E\right|$$\end{document} (Pepper, Binding independence, Ph.D. Dissertation, University of Houston, 2004; Pepper, On the annihilation number of a graph, in: Recent Advances in Electrical Engineering: Proceedings of the 15th American Conference on Applied Mathematics, pp 217–220, 2009). A set A⊆V\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$A\subseteq V$$\end{document} satisfying ∑a∈Adeg(a)≤E\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\sum \limits _{a\in A}deg (a)\le \left| E\right|$$\end{document} is an annihilation set; if, in addition, degv+∑a∈Adeg(a)>E\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$deg \left( v\right) +\sum \limits _{a\in A}deg (a)>\left| E\right|$$\end{document}, for every vertex v∈V(G)-A\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$v\in V(G)-A$$\end{document}, then A is a maximal annihilation set in G. In Larson and Pepper (Graphs with equal independence and annihilation numbers. Electron J Comb 18:180, 2011) it was conjectured that the following assertions are equivalent: (i) αG=aG\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\alpha \left( G\right) =a\left( G\right)$$\end{document}; (ii)G is a König–Egerváry graph and every maximum independent set is a maximal annihilating set. Recently, it turned out that the implication “(i)⟹\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\Longrightarrow$$\end{document}(ii)” was not true. A series of corresponding counterexamples can be found in Hiller (Counterexamples to the characterisation of graphs with equal independence and annihilation number. arXiv:2202.07529v1 [math.CO], 2022). In Levit and Mandrescu (On an annihilation number conjecture. Ars Math. Contemp. 18, 359–369, 2020), we presented an infinite family of non-bipartite König–Egerváry graphs that invalidate the “ (ii)⟹\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\Longrightarrow$$\end{document}(i)” part of this conjecture. In this paper, we provide two more infinite families of counterexamples, one consisting of trees and the other one comprising non-tree bipartite graphs. We also show that the above conjecture is true for trees with αG=4\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\alpha \left( G\right) =4$$\end{document}, disconnected non-bipartite König–Egerváry graphs with αG=4\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\alpha \left( G\right) =4$$\end{document}, and disconnected bipartite graphs with αG=4\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\alpha \left( G\right) =4$$\end{document} excluding the three following counterexamples: C4∪2K2,Domino∪K2\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$C_{4}\cup 2K_{2},Domino\cup K_{2}$$\end{document} and K3,3-e\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$K_{3,3}-e$$\end{document}.

The COVID-19 pandemic has brought new challenges to almost every aspect of parents' and their children's lives, posing an acute threat to the families' quality of life (FQOL). This study had two aims: (1) to identify changes in family coping-strategy profiles among parents pre-and during the first COVID-19 lockdown and (2) to analyze interactions between the clusters of coping strategies pre-COVID with FQOL during the first lockdown. A sample of 253 parents (58.5% mothers) of children (3 to 18 yr old) completed the Family Pandemic Oriented Personal Evaluation Scales and the FQOL Scale about their family life pre-and during the COVID-19 lockdown. Four family coping-strategy clusters were found. Differences were found between those clusters pre-and during the first COVID-19 lockdown, with a high percentage of families using the positive appraisal strategy more often. Significant interactions were found between the family coping-strategy clusters pre-COVID-19 and the FQOL factors before and during the pandemic. Most families maintained their FQOL levels during the first lockdown. Close and frequent interactions between family members had relationships with positive emotions and significant effects on well-being. Results showed that positive cognitive appraisal was a protective factor against a significant decrease in FQOL during the first COVID-19 lockdown.

Social interactions play an important role in the shaping of individual personalities and development of behavioral and physiological disturbances. Animal models represent a valuable tool in the study of the molecular and biochemical basis of social behaviors. Dominant–submissive relationship (DSR)-based models have been developed in both mice and rats for the purposes of studying the molecular basis of social behavior and psychotropic agent screening. These models have been established on the basis of the food competition paradigm. Whereas DSR models have been proven to be valid for drug testing, they have also been associated with different challenges, including low efficiency, experimental reproducibility, and testing time duration. To overcome these challenges, we employed the selective breeding approach, which has allowed us to develop mouse populations with strong characteristics of dominance and submissiveness. This model allows a dramatic increase in test efficiency, stability, and reproducibility as well as a substantial decrease in experimental duration. The selectively-bred dominant (Dom) and submissive (Sub) mice exhibit distinct differences in (a) stress-coping abilities, (b) responses to psychotropic agents, (c) inflammatory profiles, (d) gut microbiome profile, and (e) life span. Herein, we describe in detail the process of selective breeding as well as the behavioral, biochemical, and physiological characteristics of the Dom and Sub mice. We also discuss the different research directions that can be pursued by employing this model.Key wordsDominanceSubmissivenessStress resilienceSelective breedingSocial interactionsDominant–submissive relationship testAntidepressantsPsychotropic agentsDepressionAnxiety

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P.O. Box 3, 40700, Ariel, Israel

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Professor Yehuda Shoenfeld

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www.ariel.ac.il

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+972-1800660660