Airlangga University

In the current digital era, despite technological advancements and increased access to education, there remains a significant population in Indonesia that believes in traditional healing practices associated with ‘mystical’ illnesses. One such illness is sawan. This research aims to provide a comprehensive description of the forms, factors, as well as treatments or prevention of sawan through qualitative research and case studies. Data was collected through participant observation and in-depth interviews with 40 informants from various regions in Java. The findings reveal five types of sawan: sawan mayit, sawan bayi, sawan manten, sawan sambaing dalan, and sawan candhikala/sawan celeng. Additionally, the data also uncovered that sawan, along with preventive and curative measures available, include the use of mantras and traditional herbal remedies known as singgul. This research provides insights into alternative healing in the health field and serves as a foundation for further research on this subject, including studies beyond the island of Java and the exploration of the origins of sawan terminology.

Corporations have been increasingly prioritizing corporate social innovation (CSI). It has potential for creating long‐term business value and promoting sustainable social development. CSI possesses immense value due to its exceptional ability to tackle complex and pressing social issues. Despite over a decade of research on CSI, there is limited understanding about drivers of CSI from the perspective of organizational resources. The current study utilized the resource‐based view of the firm (RBV) to investigate the impact of organizational resources (such as alliance networks, innovative culture, and intellectual human capital) on CSI. This was done by examining the mediation of dynamic capabilities (exploitation and exploration). The data obtained from Malaysian public limited companies was examined using PLS‐SEM and fsQCA. The results revealed that alliance networks and innovative culture play a crucial role to drive CSI. The fsQCA analysis discovered four sufficient configurations that foster CSI. In addition to the theoretical contributions, the findings have significant implications for corporate leaders seeking CSI initiatives, as well as policy makers within governmental bodies.

Overactive bladder (OAB) is a chronic disease with the symptoms of urgency with or without incontinence. Solifenacin is an antimuscarinic drug that Excels in OAB treatment due to its specific bladder receptor targeting. While previous research had positive outcomes, reports of adverse events (AEs) highlight the need for regular updates on the safety and efficacy of solifenacin for OAB management. This study followed PRISMA 2020 guidelines and was registered to PROSPERO CRD42023445318. A comprehensive search of PubMed, ScienceDirect, and Scopus databases was conducted until July 2023. Data were analyzed using Review Manager version 5.4 (The Cochrane Collaboration, The Nordic Cochrane Centre, Copenhagen, Denmark). Solifenacin had a significantly better effect in decreasing urgency episode (mean difference (MD) = −1.09, 95% confidence interval [CI]: −1.29–−0.89, P < 0.00001), incontinence episode (MD = −0.56, 95% CI: −0.80–−0.32, P < 0.00001), micturition frequency (MD = −1.01, 95% CI: −1.16–−0.85, P < 0.00001), nocturia episode (MD = −0.13, 95% CI: −0.25–−0.01, P = 0.04), and had a higher urine volume (MD = 26.88, 95% CI: 24.17–29.59, P < 0.00001) per 24 h compared to placebo. Solifenacin had a significant number of AEs compared to placebo (MD = 1.75, 95% CI: 1.25–2.45, P = 0.001). Solifenacin significantly decreased urgency episode, incontinence episodes, micturition frequency, and nocturia episode, and had a higher urine volume per 24 h. There was a significant number of AEs in patients receiving solifenacin.

Introduction Ovarian cancer is one of the most lethal gynecological cancers. Despite diagnosis and treatment advances, survival rates have not increased over the past 32 years. This study estimated and reported the global burden of ovarian cancer during the past 32 years to inform preventative and control strategies. Methods We examined ovarian cancer incidence, mortality, and disability-adjusted life years (DALYs) using age-standardized rates from the Global Burden of Disease, Injuries, and Risk Factors Study 2021. high body mass index and occupational asbestos exposure were linked with death and DALYs. Data are presented as averages with 95% uncertainty intervals (UIs). Results Indonesia had 13 250 (8 574–21 565) ovarian cancer cases in 2021, with 5 296 (3 520–8958) deaths and 186 917 (121 866–309 820) DALYs. The burden increased by 233.53% for new cases, 221.95% for mortalities, and 206.65% for DALYs. The age-standardized rate also increased from 1990 to 2021. Ovarian cancer burden increased with age but declined in the 50+ year age group. According to the sociodemographic index, the gross domestic product per capita and number of obstetricians and oncologic gynecologists in provinces showed different trends. Conclusions Indonesian ovarian cancer rates are rising despite gynecologic oncologists in 24 of 34 provinces. These findings will help policymakers and healthcare providers identify ovarian cancer prevention and control gaps.

Work‐related stress, a major contributor to physical and mental health issues of nurses, has a direct impact on patient safety and nurses' well‐being. However, few studies have investigated the effectiveness of cognitive behavioral therapy in reducing psychological distress in nurses. Systematic search of six databases including CINAHL Plus with Full Text, Cochrane Library, Embase, Medline, PubMed, and Web of Science from their inception to February 27, 2024. The primary outcomes assessed were reductions in stress, anxiety, and depression following the implementation of cognitive behavioral therapy. A random effects model, accounting for study differences, was applied in the meta‐analyses. Egger's regression test was utilized to assess potential publication bias in the pooled analyses. The meta‐analysis included 10 studies that demonstrated the intervention's beneficial effects in reducing stress, anxiety, and depression among nurses. Despite the positive effects observed with cognitive behavioral therapy (CBT) in alleviating psychological distress among nurses, the generalizability of these findings may require further confirmation due to the diversity of cognitive behavioral therapies.

Background Studies have shown a high rate of mortality among adults despite the introduction of highly active antiretroviral therapy (HAART). However, long-term outcomes of HAART among children remain poorly documented in Ethiopia. This study aimed to estimate the survival rate and identify associated factors among HIV-infected children on antiretroviral therapy. Methods A retrospective cohort study was conducted from August to December 2022 in 13 health facilities (HFs) using records of 554 children (<15 years old) initiating HAART from 2007 to 2019. HFs were selected using probability proportional to the size of patients. Survival rate and predictors of mortality were estimated using Kaplan-Meier and Cox-proportional hazards, respectively. The analysis was done using STATA V.16.0. Result Overall mortality among HIV-positive children taking HAART in Ethiopia in 12-year follow-up was 25.5%. Moreover, the mortality rate was 24 per 100 child-year observation. Survival during the median 9.65 (95% CI=9.30 to 10.00) years of follow-up was 0.50. There was a significant drop in the survival rate from the 6th year of follow-up (0.96) to the 8th year (0.78) till the 12th year (0.18). By the end of the follow-up period, 172 (23.69%) were lost to follow-up. There was a high risk of mortality among female (adjusted HRs (AHRs) (95% CI) =1.35 (1.14 to 1.65)), those with poor adherence (AHR (95% CI) =1.29 (1.13 to 1.35)), CD4 count of ≤200 cells/mm ³ (AHR (95% CI) =1.75 (1.33 to 2.30)) and baseline haemoglobin≤12 g/dL (AHR (95% CI) =1.8 (1.66 to 1.98)). Conclusion The significant drop in the survival rate as of the 6th year follow-up and the high loss rate to follow-up call for programme attention. Close follow-up of children with low CD4 count, low haemoglobin and poor adherence could help improve survival.

Introduction Hypertension is the leading noncommunicable disease case affecting 1.28 billion individuals worldwide, with most cases located in low- and middle-income countries. While there are numerous techniques for treating mild to moderate hypertension, properly controlling severe or resistant hypertension poses substantial challenges. Ultrasound-based renal denervation (uRDN) has emerged as a promising non-pharmacological approach. This study aims to investigate the safety and efficacy of uRDN in hypertensive patients. Methods The literature search across PubMed, ScienceDirect, BMJ Journals, ProQuest, and Springer databases yielded 419 articles. A total of 395 articles were filtered, leading to 24 articles assessed for eligibility and overall analysis, which resulted in eight included studies for quantitative synthesis. Quality appraisal used RoB 2.0, while meta-analysis used RevMan 5.4. Results Our analysis results indicated significant improvements in 24-hour, daytime, and home ambulatory blood pressure measurements, favoring the uRDN over control. The mean difference (MD) for 24-hour measurements was -0.84 mmHg [95% CI -1.14, -0.55; p < 0.00001], for daytime measurements -1.27 mmHg [95% CI -1.59, -0.95; p < 0.00001], and for home measurements -1.98 mmHg [95% CI -2.32, -1.64; p < 0.00001], with moderate heterogeneity observed. Office ambulatory measurements also favored the uRDN with a significant MD of -1.51 mmHg [95% CI -1.91; -1.10; p < 0.00001]. Funnel plots revealed some outliers, indicating true heterogeneity among the studies. Conclusion uRDN was associated with a significant reduction (-2.32 to -0.10 mmHg) in blood pressure of hypertensive patients.

Background The Shoulder Pain and Disability Index (SPADI) is a widely used 13-item shoulder-specific patient-reported outcome measure for shoulder pain disorders. The English version of SPADI is easy to use and demonstrates excellent measurement properties for clinical and research settings. Purpose To translate and culturally adapt an Indonesian version of SPADI (SPADI-IDN) and then validate its use in Indonesian patients. Study Design Cohort study (Diagnosis); Level of evidence, 2. Methods Through a forward and a backward translation process, the validity of the questionnaire was investigated. The study population was 100 patients with shoulder pain who were treated in a hospital in Indonesia. The patients were asked to fill out the SPADI-IDN during their visit. To evaluate the validity of SPADI-IDN, the patients were also asked to fill out the Medical Outcomes Study 12-Item Short-Form Health Survey and the Oxford Shoulder Score. To assess the test-retest reliability, the same patients were asked to fill out the SPADI-IDN questionnaire again 1 week later. The assessment of construct validity, test-retest reliability, internal consistency, floor and ceiling effect, and measurement of error followed the COSMIN (Consensus-based Standards for the selection of health Measurement Instruments) guidelines. The Bland-Altman method was used to explore absolute agreement. Results Of the 100 eligible patients, all were used to assess construct validity, and 87 patients (87%) were used to assess test-retest reliability. Almost every established hypothesis about the correlations between SPADI-IDN and other questionnaires could be confirmed, implying good construct validity. No floor or ceiling effects were found. The intraclass correlation value was 0.99, indicating strong test-retest reliability. A Cronbach α was 0.95, indicating a good internal consistency. The Bland-Altman analysis did not reveal any bias. The standard error of measurement and the minimal detectable change at the individual and group levels were 2.65, 7.3, and 0.7, respectively. Conclusion The SPADI-IDN represents a valid and reliable tool for measuring pain and disability in patients with shoulder pain disorders.

Background and Aim: In the global pig farming industry, artificial insemination (AI) is widely used to propagate high-quality genetics using processed semen that can be stored for extended periods. However, boar sperm are particularly susceptible to oxidative damage during storage and cryopreservation because of their high polyunsaturated fatty acid content. This study aimed to systematically review the impact of resveratrol (RVT), a potent antioxidant, on the preservation of boar semen. Materials and Methods: A comprehensive meta-analysis was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Relevant articles were retrieved from databases such as Scopus, ScienceDirect, and PubMed using specific keywords. After a thorough screening, 10 studies were selected for inclusion. Data extracted from these studies included parameters such as sperm motility, viability, DNA integrity, and lipid peroxidation levels. Results: Resveratrol supplementation in boar semen extenders significantly improved sperm quality under various storage conditions, including waterbath and cooled and frozen semen. RVT’s antioxidative properties effectively reduced reactive oxygen species and prevented oxidative stress-related damage to sperm cells. Conclusion: The addition of resveratrol to semen extenders enhances the preservation of boar sperm by mitigating oxidative damage, potentially increasing the success rate of AI in the swine industry. This study highlights the need for further research to optimize RVT dosage and application methods for different semen preservation techniques. Keywords: antioxidant, artificial insemination, boar semen preservation, livestock and gene bank, resveratrol.

Aims Clinical high-risk for psychosis (CHR-P) states exhibit diverse clinical presentations, prompting a shift towards broader outcome assessments beyond psychosis manifestation. To elucidate more uniform clinical profiles and their trajectories, we investigated CHR-P profiles in a community sample. Methods Participants ( N = 829; baseline age: 16–40 years) comprised individuals from a Swiss community sample who were followed up over roughly 3 years. latent class analysis was applied to CHR-P symptom data at baseline and follow-up, and classes were examined for demographic and clinical differences, as well as stability over time. Results Similar three-class solutions were yielded for both time points. Class 1 was mainly characterized by subtle, subjectively experienced disturbances in mental processes, including thinking, speech and perception (basic symptoms [BSs]). Class 2 was characterized by subthreshold positive psychotic symptoms (i.e., mild delusions or hallucinations) indicative of an ultra-high risk for psychosis. Class 3, the largest group (comprising over 90% of participants), exhibited the lowest probability of experiencing any psychosis-related symptoms (CHR-P symptoms). Classes 1 and 2 included more participants with functional impairment and psychiatric morbidity. Class 3 participants had a low probability of having functional deficits or mental disorders at both time points, suggesting that Class 3 was the healthiest group and that their mental health and functioning remained stable throughout the study period. While 91% of Baseline Class 3 participants remained in their class over time, most Baseline Classes 1 (74%) and Class 2 (88%) participants moved to Follow-up Class 3. Conclusions Despite some temporal fluctuations, CHR-P symptoms within community samples cluster into distinct subgroups, reflecting varying levels of symptom severity and risk profiles. This clustering highlights the largely distinct nature of BSs and attenuated positive symptoms within the community. The association of Classes 1 and 2 with Axis-I disorders and functional deficits emphasizes the clinical significance of CHR-P symptoms. These findings highlight the need for personalized preventive measures targeting specific risk profiles in community-based populations.

Background The World Professional Association for Transgender Health guidelines Standards of Care 8 draw on ethical arguments based on individual autonomy, to argue that healthcare and other professionals should be advocates for trans people. Such guidelines presume the presence of medical services for trans people and a degree of consensus on medical ethics. Very little is known, however, about the ethical challenges associated with both providing and accessing trans healthcare, including gender affirmation, in the Global South. In light of the challenges associated with medical and legal gender affirmation in Indonesia, we conducted a qualitative study to understand the views of trans people, healthcare providers, and legal practitioners. Methods In this qualitative study, we drew on a participatory methodology to conduct 46 semi-structured interviews between October and December 2023, with trans people (10 trans feminine people and 10 trans masculine people, each interviewed twice) and key informants (three healthcare providers and three lawyers and paralegals). Trans people were a central part of the research team from inception through to analysis and writing. Participants were recruited via community-led sampling. Data analysis of interview data took place through an immersion/crystallisation technique and preliminary inductive coding which highlighted key quotes. We focused on an inductive analysis using participant narratives to identify key concepts in the ethics of gender affirmation in Indonesia. Results We characterize the ethics of supportive healthcare workers, community members, and family members, as that akin to “accomplices,” a concept of ethics used in theories of racial justice which evaluate a willingness to support people to navigate laws and regulations which perpetuate injustices and violence. Overall, both trans people and key informants shared an understanding that the legal status of gender-affirming medical care was particularly ambiguous in Indonesia due to a lack of clarity in both laws and regulations. For trans participants, ethical arguments for the validity of legal and medical gender affirmation was premised on evidence that their gender identity and expression was already recognized within society, even if limited to immediate friends and family. Given that all participants expressed a desire for gender affirmation, but such services were widely unavailable, accomplices played a crucial role in supporting trans people to access healthcare. Conclusions An empirical study based on an “ethics from below” helps to show that arguments grounded in autonomy, or based on biomedical evidence, are unlikely to alter unjust laws or facilitate a change to pathologizing guidelines governing understanding of trans people’s healthcare and legal needs in Indonesia. We provide an analysis that is sensitive to the ethics of facilitating gender affirmation in a context where that process is inherently social, and often articulated in relation to a prevailing religious morality.

This study explores religious tolerance attitudes among high school students in Batu City, a city experiencing urban transition. Utilizing a qualitative case study approach, data were gathered through in-depth interviews with key informants, specifically student council presidents from five high and vocational schools selected through purposive sampling. These presidents are knowledgeable about school and community dynamics. Additional relevant informants from each school were also interviewed. A literature review incorporated previous research to enrich the analysis. The findings indicate that religious tolerance among high school students in Batu City requires improvement, with instances of intolerance stemming from ethnic, religious, and racial differences. However, religious literacy programs could promote critical thinking, dialogue, and understanding of religious diversity, thereby enhancing tolerance. Currently, the implementation of these programs lacks strategic planning, which allows intolerant attitudes to persist. The study emphasizes the significant roles of family, schools, peer environments, and social media in shaping effective religious literacy. It suggests that without a structured approach to religious literacy, intolerant behaviors may continue to arise. Well-designed programs could enhance students' awareness and tolerance, contributing to broader social harmony in urban transition areas like Batu City.

This study investigates the relationship between self-efficacy, job crafting, and innovative work behavior in Indonesian prospective police investigators. The research, conducted at the National Police Education and Training Institute, utilized a quantitative approach, gathering data from 448 participants via a structured online questionnaire employing a five-point Likert scale. The analysis was conducted using SmartPLS4. The findings indicate that self-efficacy does not directly affect innovative work behavior. However, job crafting serves as a complete mediator in this relationship, underscoring its essential role in promoting innovation within organized professional environments. This study enhances the current body of literature by applying Bandura’s Social Cognitive Theory to law enforcement settings, highlighting the intricate interplay among cognitive, behavioral, and environmental elements. Incorporating job crafting-focused training in police education is recommended to improve adaptability and innovation, thereby addressing the operational challenges faced by law enforcement in the post-pandemic context. Future research should investigate these dynamics across various cultural and organizational contexts to further validate the findings and examine longitudinal changes throughout an officer’s career.