Fig 2 - uploaded by Luis De la Cruz-Merino
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Immunohistochemical staining of inflammatory background in HL: T lymphocytes (CD4 and CD8), NK cells (CD56 and CD57) and cytotoxic cells (GrB and TIA-1).
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Context 1
... pattern explains the abundant mixture of inflammatory cells, stromal changes and the predominance of Th2 cells between the various subpopulations of lymphoid cells in the tumoral microenvironment of HL ( Swerdlow et al., 2008b). A predominance of CD4 + T lymphocytes in the background of tumoral cells in addition to a high number of cytotoxic cells (CD8, CD57, TIA-1) has been observed in the majority of HL- tissues (Figure 2) (Alvaro-Naranjo et al., 2005; Oudejans et al., 1997;Poppema et al., 1998). Fig. 3. Representation of the two immune patterns observed in HL significantly associated with their clinicopathological features. ...