Source publication
Preprint
Full-text available
The present study investigated the effects of perinatal exposure to glyphosate-based herbicide (GBH) on liver of immature Wistar rats. Female rats were exposed to GBH (70 mg glyphosate/Kg body weight/day) in drinking water from gestation day 5 and continually up to lactation day 15. The perinatal exposure to GBH increased ⁴⁵ Ca ²⁺ influx in offspri...

Contexts in source publication

Context 1
... established that perinatal exposure to GBH leads to oxidative stress, we investigated the activity of enzymatic antioxidant defense systems in offspring's liver. Results showed that GBH exposure downregulated G6PD and SOD in offspring's liver ( Fig. 3A and 3E). Conversely, GR, GST and CAT activities were increased (Fig. 3B, 3D and 3F), while GPx activity was unaltered by the perinatal exposure to herbicide (Fig. ...
Context 2
... established that perinatal exposure to GBH leads to oxidative stress, we investigated the activity of enzymatic antioxidant defense systems in offspring's liver. Results showed that GBH exposure downregulated G6PD and SOD in offspring's liver ( Fig. 3A and 3E). Conversely, GR, GST and CAT activities were increased (Fig. 3B, 3D and 3F), while GPx activity was unaltered by the perinatal exposure to herbicide (Fig. ...
Context 3
... stress, we investigated the activity of enzymatic antioxidant defense systems in offspring's liver. Results showed that GBH exposure downregulated G6PD and SOD in offspring's liver ( Fig. 3A and 3E). Conversely, GR, GST and CAT activities were increased (Fig. 3B, 3D and 3F), while GPx activity was unaltered by the perinatal exposure to herbicide (Fig. ...