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Beyond group classification: probabilistic differential diagnosis of frontotemporal dementia and Alzheimer’s disease with MRI and CSF biomarkers.
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  • Nov 2023
Background Neuroimaging and fluid biomarkers are used in clinics to differentiate frontotemporal dementia (FTD) from Alzheimer’s disease (AD) and other neurodegenerative and non-neurodegenerative disorders. We implemented a machine learning (ML) algorithm that provides individual probabilistic scores for these patients based on magnetic resonance i...
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... Important MRI regions for classication Figure 3 shows the region weights associated with each comparison. In summary, when comparing AD versus CTR, the GM volume of the hippocampus, putamen, and amygdala played the most crucial role. ...

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