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Purpose: Childhood cancer survivors (CCS) are at risk for increased morbidity and reduced quality of life associated with treatment-related late effects. In Germany, however, only a few of the more than 40,000 CCS registered in the German Childhood Cancer Registry (GCCR) currently benefit from adequate clinical long-term follow-up (LTFU) structures...

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... were young adults aged 18-24 years (62.5%). On average, 16.4 years (range 5.0-57.7) had passed since cancer diagnosis. Detailed patient characteristics are presented in Table 2. CCS in our cohort were mainly diagnosed with leukaemia (36.5%) or lymphoma (26.4%) in childhood or adolescence, while 13.9% had previously suffered from a brain tumour (Fig. 1). According to RG stratication 19.2% of participating patients had a low (RG1), 25.0% an intermediate (RG2) and 55.8% a high risk (RG3) for late effects following their cancer treatment (Table 2). MD: missing data; SD: standard deviation; IQR: interquartile range; a referring to age at time of rst clinical follow-up examination; b ...
Context 2
... examination was documented as 2016, presupposing cancer diagnosis prior to that (> 5 years since diagnosis Occurrence of health conditions in CCS differed among RG. In most categories, disorders consistently affected more CCS allocated to RG3 than CCS of RG1 or RG2 (Table 3). Overall, the number of affected organ systems increased with each RG (Fig. ...

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Article
Full-text available
Purpose Childhood cancer survivors (CCS) are at risk for increased morbidity and reduced quality of life associated with treatment-related late effects. In Germany, however, only a few of the more than 40,000 CCS registered in the German Childhood Cancer Registry (GCCR) currently benefit from adequate clinical long-term follow-up (LTFU) structures....