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Background The colonization of Extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) in bloodstream infections (BSIs) has been increased dramatically worldwide, and it was associated with worse clinical outcomes in patients with malignancy. We performed the meta-analysis to investigate the prognosis and risk factors in BSIs caused by...
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... results showed that in patients with malignancy, ESBL-PE infections was associated with a higher mortality risk from BSIs than non-ESBL-PE infections (RR = 2.21, 95 % CI: 1.60-3.06, P < 0.001) (Figure 2), with a significant between-study heterogeneity (I 2 = 78.3%, P < 0.001). ...
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... then carried out the sensitivity analysis by omitting each study in turn. As summarized in Figure S2, the pooled RRs and 95% CIs of mortality ranged from 2.03 (1.53-2.68) to 2.36 (1.72-3.25). The results of the sensitivity analysis show that our results are stable and reliable since there were no individual studies influenced the overall results. ...
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... that FN/ neutropenia was not the risk factor for mortality in BSIs caused by ESBL-PE among patients with malignancy. (14, 16, 21, 24) Hence, the accuracy of the conclusion needs to be further confirmed. The combined RR of sensitivity analysis further confirmed the stability of the results. ...
