Citations

... [5] Primary rifampicin resistance has been reported from different regions in India. [6] Lavania M et al., 2015 reported primary drug resistance to rifampicin in 7 out of 16 new cases of leprosy. [7] Singh SK et al. have reported fluoroquinolone resistance in 21% (8/32) patients, and none with standard MDT; however, their sample size was small and relapse cases were few. ...
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Resistance to antileprosy drugs is one of the main contributors for the persistence of leprosy in the present era. In the absence of universal antimicrobial resistance (AMR) surveillance through the national program, the indications for resistance testing remain a important dilemma to clinicians. WHO recommendations mainly focus on clinical relapse, which could be picked up late with continued transmission and repeated leprosy reactions in the patient. We report here a series of eighteen leprosy cases who were tested for AMR in view of the positive morphological index after completion of multidrug therapy, chronic Erythema nodosum leprosum, and clinical relapse.