a) Solvent switched synthesis of amides and tertiary amines in THF and MeOH. b) Mechanism for the synthesis of amides (7) and tertiary amines (8).

a) Solvent switched synthesis of amides and tertiary amines in THF and MeOH. b) Mechanism for the synthesis of amides (7) and tertiary amines (8).

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Solvent plays an important role in many chemical reactions. The C−H activation has been one of the most powerful tools in organic synthesis. These reactions are often assisted by solvents which not only provide a medium for the chemical reactions but also facilitate reaching to the product stage. The solvent helps the reaction profile both chemical...