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Visual representation of the consequences of different antimicrobial therapies shown through Kaplan‒Meier curves. (A) There was no difference in 30-day mortality among patients who were given empirical carbapenems. (B-C) Patients who received empirical tigecycline had a negative prognosis within 30 days, whereas those who received empirical polymyxin B had a survival benefit within the same time frame. (D) There was no variation in the 30-day mortality rate among patients who received combination therapy with carbapenem. (E) Individuals who received combination therapy involving tigecycline experienced an unfavorable prognosis within a 30-day period. (F) On the other hand, individuals who received combination therapy involving polymyxin B experienced a survival advantage for a period of 30 days

Visual representation of the consequences of different antimicrobial therapies shown through Kaplan‒Meier curves. (A) There was no difference in 30-day mortality among patients who were given empirical carbapenems. (B-C) Patients who received empirical tigecycline had a negative prognosis within 30 days, whereas those who received empirical polymyxin B had a survival benefit within the same time frame. (D) There was no variation in the 30-day mortality rate among patients who received combination therapy with carbapenem. (E) Individuals who received combination therapy involving tigecycline experienced an unfavorable prognosis within a 30-day period. (F) On the other hand, individuals who received combination therapy involving polymyxin B experienced a survival advantage for a period of 30 days

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Carbapenem-resistant Enterobacterales sepsis following endoscopic retrograde cholangiopancreatography: risk factors for 30-day all-cause mortality and the development of a nomogram based on a retrospective cohort
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  • Aug 2024
Background Endoscopic retrograde cholangiopancreatography (ERCP) has become a routine endoscopic procedure that is essential for diagnosing and managing various conditions, including gallstone extraction and the treatment of bile duct and pancreatic tumors. Despite its efficacy, post-ERCP infections – particularly those caused by carbapenem-resista...
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... This case presents an unusual occurrence of TLS triggered by ERCP, a procedure commonly performed for biliary decompression. TLS, in this context, is believed to result from the physical manipulation of the tumor and the release of intracellular components, including potassium, phosphate, and uric acid, into the bloodstream [8]. This metabolic surge overwhelms the kidneys' ability to excrete these substances, leading to acute kidney injury (AKI), hyperkalemia, hyperphosphatemia, hyperuricemia, and secondary hypocalcemia caused by phosphate precipitation with calcium [9]. ...
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