Fig 7 - uploaded by Juan Luis Alcazar
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Transvaginal ultrasound showing a cystic–solid mass with abundant vascularization within the solid portions of the tumor
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Epithelial ovarian cancer remains as the most deadly gynecological malignancy and it is the seventh leading cause of cancer in women in developed countries. Worldwide more than 200,000 new cases are diagnosed annually, resulting in more than 140,000 deaths. Histologically, ovarian malignancies are classified in two broad groups: epithelial and non-...
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Abstract
Introduction: BCL-2 was the first anti-death gene discovered a milestone with far reaching implications for tumor biology. BCL-2 expression explains ovarian cancer resistance to chemotherapeutic drug explaining recurrence and poor survival.
Materials and Methods: In this study we tested the expression BCL-2 protein in 59 ovarian tumors us...
Epithelial ovarian cancer (EOC) represents the most frequently occurring gynecological malignancy, accounting for more than 70% of ovarian cancer deaths. Preoperative imaging plays an important role in assessing the extent of disease and guides the next step in surgical decision-making and operative planning. In this article, we will review the mul...
Estrogen signaling influences the development and progression of ovarian tumors, but the underlying mechanisms are not well understood. In a previous study we demonstrated that impairment of estrogen receptor alpha (ERα)-mediated olfactomedin 4 (OLFM4) expression promotes the malignant progression of endometrioid adenocarcinoma, and we identified O...
Background: The ovaries frequently are the site for various primary tumors. Correct intraoperative diagnosis is crucial. The application of imprint cytology is very useful where frozen section facility is not available. The present study is a comparison of imprint cytology and frozen section during intraoperative consultation for various types of b...
Background: Endometriosis is a prevalent benign condition arising from female reproductive system and affects about 7% to 10% of females. The association of this disorder with epithelial ovarian tumors has been a matter of interest in gynecology. Objectives: The present study was conducted to assess the association between endometriosis and differe...
