Transmembrane structure of Rhomboids using TMRPres2D 45 . Rhomboids a, b, c and d are from S. coelicolor, and e is from S. sviceus active sites are highlighted with a red circle.

Transmembrane structure of Rhomboids using TMRPres2D 45 . Rhomboids a, b, c and d are from S. coelicolor, and e is from S. sviceus active sites are highlighted with a red circle.

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Proteolytic enzymes are ubiquitous and active in a myriad of biochemical pathways. One type, the rhomboids are intramembrane serine proteases that release their products extracellularly. These proteases are present in all forms of life and their function is not fully understood, although some evidence suggests they participate in cell signaling. St...