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Source publication
Background
The optimal timing of enteral nutrition (EN) initiation in predicted severe acute gallstone pancreatitis (SAGP) and its influence on disease outcomes are not well known.
Methods
We conducted a retrospective study of patients with predicted SAGP treated with endoscopic retrograde cholangiopancreatography and EN. The patients were classif...
Context in source publication
Context 1
... total of 91 pathogenic bacterial strains were isolated from 60 specimens, including 47 transpapillary drainage specimens, 7 blood specimens, and 6 percutaneous drainage specimens ( Table 4). Forty-six Gram-negative bacterial strains accounted for 50.5% of the isolates, 36 Gram-positive bacterial strains for 39.6%, and 9 fungi for 9.9%. ...Similar publications
Citations
... 18 Another study also showed that EN initiation within 48 h was associated with decreased in-hospital mortality and length of hospital stay compared with delayed EN (>48 h) in predicted severe acute gallstone pancreatitis. 19 In 2010, a retrospective investigation performed by Hegazi and colleagues found that the time to start jejunal feeding was much longer in nonsurvivors than in survivors (17 vs 7 days). 20 Because of the retrospective nature of the study, "survivor bias" can not be ruled out, because survivors may simply better tolerate EN feeding. ...
A significant proportion of patients (10%–20%) with acute pancreatitis develop severe acute pancreatitis characterized by pancreatic necrosis, systemic inflammation, and organ failure, commonly requiring intensive care unit (ICU) admission. In this specific population, nutrition therapy is more challenging than that in the general ICU population, primarily because of inevitable gastrointestinal involvement by pancreatic inflammation. In this review, we discussed several key aspects of nutrition therapy in this population, including key pathophysiology that may impede nutrition therapy, the timing and implementation of enteral nutrition and parenteral nutrition, the importance of specific nutrient supplements, and the long‐term outcomes that may be addressed by nutrition therapy.
Introduction
Enteral feeding is essential for hospitalized patients unable to consume oral nutrition. However, it poses a risk of bacterial contamination, leading to infections and increased morbidity and mortality.
Method
Studies have shown that contaminated enteral feeds are associated with longer hospital stays and worsened patient outcomes. Common pathogens include Gram-negative bacilli (e.g., Serratia spp., Klebsiella spp., Enterobacter spp.), coagulase-negative staphylococci, and Clostridium difficile. Preventing contamination requires identifying and mitigating potential routes. This comprehensive approach encompasses careful practices during production, storage, preparation, and administration of enteral feeds.
Result
Early initiation of enteral feeding has also been linked to lower infection rates. Standardized protocols, hand hygiene adherence, routine monitoring for infection signs, and ongoing staff education are crucial for safe enteral feeding. Further research is needed to better understand risk factors for contamination and evaluate the effectiveness of preventive interventions.
Conclusion
Addressing these knowledge gaps can significantly improve the quality of enteral feeding and reduce infection burden in hospitalized patients.
