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Fig 1 - The structure and flexibility of conical HIV-1 capsids determined within intact virions

Fig. 1. The structure of the CA hexamer. (A) Computational slice through a representative tomographic reconstruction of HIV-1 virions. Scale bar, 100 nm. Inset shows a computational slice through the top of the core in the boxed virion, indicating that individual hexamers can be resolved. (B) Cryo-ET reconstruction of the mature CA hexameric lattice (gray isosurface) viewed from outside the core. The final structural model of the hexamer is shown, with the NTD in cyan and the CTD in orange. One monomer is highlighted in blue (NTD) and red (CTD). (C) As in (B), viewed perpendicular to the lattice. See also movie S1. 
The structure of the CA hexamer. (A) Computational slice through a representative tomographic reconstruction of HIV-1 virions. Scale bar, 100 nm. Inset shows a computational slice through the top of the core in the boxed virion, indicating that individual hexamers can be resolved. (B) Cryo-ET reconstruction of the mature CA hexameric lattice (gray isosurface) viewed from outside the core. The final structural model of the hexamer is shown, with the NTD in cyan and the CTD in orange. One monomer is highlighted in blue (NTD) and red (CTD). (C) As in (B), viewed perpendicular to the lattice. See also movie S1. 
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