The simplest case study of the general RC model would include two resources and two strains, one of which (the engineered one) reduces the loss of R 2 . The populations of the wild type and synthetic strains are indicated by N w and N s , respectively. The synthetic would be obtained by a small engineering of the initial strain, here indicated as an open circle (indicating for example an engineered plasmid).

The simplest case study of the general RC model would include two resources and two strains, one of which (the engineered one) reduces the loss of R 2 . The populations of the wild type and synthetic strains are indicated by N w and N s , respectively. The synthetic would be obtained by a small engineering of the initial strain, here indicated as an open circle (indicating for example an engineered plasmid).

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The possibility of abrupt transitions threatens to poise ecosystems into irreversibly degraded states. Recently, it has been proposed the use of engineered microbiomes in endangered ecosystems to prevent them to cross tipping points and avoid collapse. Potential targets for such interventions include some of the most prominent life-support systems...

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... defined above, this engineered microorganism is designed to enhance the stability of one of the resources by reducing its loss. The basic diagram of this model is summarised in Figure 2. In this section we exploit the simplicity of this low-dimensional scenario along with an extra constraint that allows to define basic inequalities required for the synthetic strain to be successful. ...

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